Serum ZAG Levels Were Associated with eGFR Mild Decrease in T2DM Patients with Diabetic Nephropathy by Lingling Xu, Weihong Yu, Meng Niu, Caixia Zheng, Bin Qu, Yan Li, Jing Wang, Ping Huang, O. Wang, Fengying Gong

“…A total of 438 T2DM patients (61.3 ± 4.0 y) were recruited and the demographic, anthropometric, and biochemical parameters were all collected. Serum ZAG levels were determined by commercially available ELISA kits. …”
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Effect of Melatonin as an Antioxidant Drug to Reverse Hepatic Steatosis: Experimental Model by Blanca Martínez Soriano, Antonio Güemes, Guillermo Pola, Azucena Gonzalo, Pilar Palacios Gasós, Ana C. Navarro, Roberto Martínez-Beamonte, Jesús Osada, José J. García

“…The effect of melatonin on fat metabolism can be summarized as a decrease in lipid peroxidation and a decrease in oxidative stress, biochemical phenomena intimately related to fat deposition in the hepatocyte. …”
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Lipid Profile in Adolescent Girls with Type 1 Diabetes Mellitus and Hyperandrogenemia by Agnieszka Zachurzok, Grazyna Deja, Aneta Gawlik, Agnieszka Drosdzol-Cop, Katarzyna Klimek, Ewa Malecka-Tendera

“…Lipid levels in 16 diabetic girls with biochemical hyperandrogenemia (T1DM-H) aged 16.3 ± 1.2 years were compared to 38 diabetic girls with normal androgen levels (T1DM-N) aged 15.8 ± 1.2 years. 15 healthy girls served as controls (CG). …”
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Adrenomedullin 2 attenuates anxiety-like behaviors by increasing IGF-II in amygdala and re-establishing blood–brain barrier by Denian Wang, Zhi Yang, Pengfei Wu, Qingyan Li, Chunyan Yu, Ying Yang, Yuefan Du, Mengwei Jiang, Junpeng Ma

“…Based on transcriptome analysis and biochemical analyses, we found that ADM2 facilitates the expression of insulin-like growth factor 2 (IGF-II), which then triggers the activation of the AKT-GSK3β-mTOR signaling pathway via the IGF-II receptor (IGF-IIR), rather than the IGF-I receptor (IGF-IR). …”
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Effects of Artemisia argyi leaf water extract (AWE) on growth performance, muscle quality, intestinal microbial, and metabolomics of common carp (Cyprinus carpio) by Di Sun, Nanyang Zeng, Yingjia Pan, Qingsong Shu, Jixing Zou, Yingshi Huang, Guoxia Wang, Jun Shi

“…The effects of AWE supplementation were assessed through various parameters including growth performance, flesh quality, biochemical indices, tissue structure, intestinal microbiota composition, and metabolomics analysis. …”
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Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells by Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S. Alam, Christina M. Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D. Ashwell, Klaus Strebel, Kyung S. Lee

“…Through affinity purification, biochemical, and cellular analyses, we discover that Vpr, an accessory protein of HIV-1, hijacks the centriole duplication machinery and induces centrosome amplification and aneuploidy. …”
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Acute Exposure to Microcystin-Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters by Luiza Wilges Kist, Angelo Luis Piato, João Gabriel Santos da Rosa, Gessi Koakoski, Leonardo José Gil Barcellos, João Sarkis Yunes, Carla Denise Bonan, Maurício Reis Bogo

“…Behavioral repertoire represents the consequence of a diversity of physiological and biochemical alterations. In this study, we assessed behavioral patterns and whole-body cortisol levels of adult zebrafish (Danio rerio) exposed to cell culture of the microcystin-producing cyanobacterium M. aeruginosa (MC-LR, strain RST9501). …”
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Identification and characterization of Serratia nematophila and Acinetobacter guillouiae from putrid-skin disease lesions in farmed Chinese spiny frog (Quasipaa spinosa) by Ling Guo, Xiyu Jin, Dan Yang, Li Wei, Jie Chen, Zhihua Lin, Li Ma

“…Two pathogenic strains, GL-XJ7 and GL-XJ11, were isolated from disease lesions and identified as Serratia nematophila and Acinetobacter guillouiae, respectively, through morphological, physiological, biochemical, and molecular analyses including 16S rDNA sequencing and phylogenetic tree construction. …”
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Effect of Fish Meal Substitution with Black Soldier Fly (Hermetia illucens) on Growth Performance, Feed Stability, Blood Biochemistry, and Liver and Gut Morphology of Siamese Fight... by Zulhisyam Abdul Kari, Guillermo Téllez-Isaías, Noor Khalidah Abdul Hamid, Nor Dini Rusli, Khairiyah Mat, Suniza Anis Mohamad Sukri, Muhammad Anamul Kabir, Ahmad Razali Ishak, Nazri Che Dom, Abdel-Wahab A. Abdel-Warith, Elsayed M. Younis, Martina Irwan Khoo, Faizuan Abdullah, Md Shahjahan, Md Fazle Rohani, Simon J. Davies, Lee Seong Wei

“…Similar blood haematology and biochemical properties, including corpuscular volume, lymphocytes, white blood cells, red blood cells, haematocrit, albumin, and alkaline phosphatase, were the highest (p<0.05) in the 13% BSFL diet group compared to the other treatment groups. …”
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Effect of Dietary Supplementation of <i>Durvillaea Antarctica</i> Meal on Production and Meat Quality Traits of Lambs by John Quiñones, Rodrigo Huaquipán, Rommy Díaz, Isabela Pérez Núñez, Matías Cortes, Ailín Martínez, Gastón Sepúlveda, Lidiana Velaszquez, David Cancino, Erwin Paz, Néstor Sepulveda

“…The dietary treatments did not significantly affect body weight and blood biochemical parameters. However, changes were observed in meat quality traits, including increased redness and reduced luminosity in the loin for the high inclusion treatment, in addition to slight alterations in pH and lower lipid oxidation in lambs’ meat fed <i>Durvillaea antarctica</i>. …”
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A Study on the Dietary Yeast Polysaccharide Supplementation in Growth Performance, Antioxidant Capacity, and Immunity of Juvenile Largemouth Bass (<i>Micropterus salmoides</i>) by Junjie Qin, Haifeng Mi, Mingchun Ren, Dongyu Huang, Hualiang Liang, Lu Zhang, Tao Teng, Heng Yin

“…There was no significant effect on any of the other growth indicators. Plasma biochemical indices showed that the 0.10Y group exhibited the highest plasma alkaline phosphatase content and the 0.20Y group exhibited the highest plasma glucose content. …”
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Escherichia coli combination with PD-1 blockade synergistically enhances immunotherapy in glioblastoma multiforme by regulating the immune cells by Guochen Li, Haiyan Yang, Tengfei Ke, Na Tan, Xiaolan Du, Xirui Duan, Xinyan Zhou, Guangrong Zheng, Chengde Liao

“…Complete blood cell count, blood biochemical analysis, hematoxylin and eosin (H&E) staining, and agar plate culture were employed to evaluate the biosafety and tumor-targeting capability of E. coli. …”
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Central Precocious Puberty and Response to GnRHa Therapy in Children with Cerebral Palsy and Moderate to Severe Motor Impairment: Data from a Longitudinal, Case-Control, Multicentr... by Patrizia Bruzzi, Maria Francesca Messina, Alessandra Bartoli, Barbara Predieri, Laura Lucaccioni, Simona Filomena Madeo, Alberto Verrotti, Filippo De Luca, Lorenzo Iughetti

“…This is a longitudinal, observational, retrospective, case-control study involving 22 children affected by CPP and CP (group A), 22 paired with CP but without CPP (group B), and 22 children with CPP without CP. Auxological, biochemical, and instrumental data were collected at diagnosis of CPP and at 2 follow-up visits. …”
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Distinct lipidomic profiles but similar improvements in aerobic capacity following sprint interval training versus moderate-intensity continuous training in male adolescents by Wantang Su, Jianming Liu, Jianming Liu, Aozhe Wang, Haifeng Zhang, Yaqi Sun, Zhiyi Yan, Michael Svensson, Ji-Guo Yu, Li Zhao

“…Anthropometric, VO2peak, and serum biochemical data were analyzed using two-way repeated analysis of variance, while targeted lipidomic analysis was performed by principal component analysis and paired-sample t-test.ResultsVO2peak significantly improved from 39.05 ± 8.17 to 47.52 ± 8.51 [F (1, 44) = 14.75, p &lt; 0.05] for MICT and from 40.13 ± 6.37 to 48.42 ± 7.01 [F (1, 44) = 14.75, p &lt; 0.05] for SIT. …”
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Effects of Fermented Soybean Meal Substituting Plant Protein and Fish Meal on Growth, Flesh Quality, and Intestinal Microbiota of Largemouth Bass (Micropterus salmoides) by Beibei Guo, Lingling Huang, Xiaoqin Li, Yunfeng Chen, Tianyu Huang, Lizhou Ma, Xiangjun Leng

“…The flesh superoxide dismutase (SOD) and total antioxidant capacity (TAOC) activities in FSM-20 and FSM-10-FM groups and glutathione peroxidase (GSH-Px) activity in FSM-10-FM group were increased (P<0.05), while the lactic acid content in FSM-20 group was decreased, when compared to FSM-0 group (P<0.05). In serum biochemical indexes, the glucose, total protein, cholesterol and malondialdehyde contents in the three FSM groups, and the triglyceride content in FSM-10-SM and FSM-20 groups were significantly lower than those of FSM-0 group (P<0.05). …”
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Replacing rice straw with peanut vine and Broussonetia papyrifera silage in beef cattle feed reduced the use of soybean meal by Xin Yi, Yueming Li, Yue Liu, Minzhe Zhang, Zhenming Zhou, Qingxiang Meng, Hao Wu

“…The present study investigated whether replacing dietary rice straw with peanut vine (PEV) and Broussonetia papyrifera silage (BPS) reduces the use of soybean meal and explored its effects on the growth performance, blood biochemical indicators, serum metabolomics, and meat quality of fattening bulls. …”
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Humoral and Cellular Immunity After Vaccination Against SARS-CoV-2 in Relapsing-Remitting Multiple Sclerosis Patients Treated with Interferon Beta and Dimethyl Fumarate by Marcin Bazylewicz, Monika Zajkowska, Monika Gudowska-Sawczuk, Rafał Kułakowski, Jan Mroczko, Dagmara Mirowska-Guzel, Joanna Kulikowska-Łoś, Agata Czarnowska, Barbara Mroczko, Jan Kochanowicz, Alina Kułakowska

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Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice by Bing Li, Yu Cheng, Songyan Yu, Li Zang, Yaqi Yin, Jiejie Liu, Lin Zhang, Yiming Mu

“…One week after the sixth infusion, intraperitoneal glucose tolerance tests and insulin tolerance tests were performed and the blood and liver were harvested for biochemical and histopathological examinations. Quantitative real-time reverse transcriptase polymerase chain reaction (qRT-PCR), immunofluorescence staining, and western blot were performed to monitor the expression of the lipid metabolism- and regulatory pathway-related genes. …”
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Vitamin D binding protein genetic isoforms, serum vitamin D, and cancer risk in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. by Stephanie J Weinstein, Dominick Parisi, Alison M Mondul, Tracy M Layne, Jiaqi Huang, Rachael Z Stolzenberg-Solomon, Regina G Ziegler, Mark P Purdue, Wen-Yi Huang, Christian C Abnet, Neal D Freedman, Kai Yu, Demetrius Albanes

“…Associations between vitamin D biochemical status and cancer may be modified by vitamin D binding protein isoforms which are encoded by GC (group-specific component). …”
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Serum levels of oxidative stress, IL-8, and pepsinogen I/II ratio in Helicobacter pylori and gastric cancer patients: potential diagnostic biomarkers by Marwa Nasier-Hussain, Jaleel Najah Samanje, Khatere Mokhtari, Mohsen Nabi-Afjadi, Zeinab Fathi, Asieh Hoseini, Elham Bahreini

“…Methods The study comprised individuals with Helicobacter pylori (H.pylori) infection, gastric cancer patients, and healthy individuals. Biochemical parameters such as FBS (fasting blood sugar), lipid profile, and liver and kidney functional factors were evaluated using colorimetric techniques. …”
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