Food-derived peptides with inhibitory capacity for HMG-CoA reductase activity: a potential nutraceutical for hypercholesterolemia by Guillermo Santos-Sánchez, Ana Isabel Álvarez-López, Eduardo Ponce-España, Patricia Judith Lardone, Antonio Carrillo-Vico, Ivan Cruz-Chamorro

“…Statins are the most prescribed lipid-lowering drugs to treat hypercholesterolemia and prevent CVDs. The biochemical mechanism of statins consists of competitive inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase enzyme (HMG-CoAR), the limiting enzyme in cholesterol biosynthesis. …”
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Immunomodulatory Effect of Phage Depolymerase Dep_kpv74 with Therapeutic Potential Against K2-Hypervirulent <i>Klebsiella pneumoniae</i> by Nikolay V. Volozhantsev, Maria A. Makarova, Alena S. Kartseva, Marina V. Silkina, Valentina M. Krasilnikova, Egor A. Denisenko, Alexander I. Borzilov, Victoria V. Firstova

“…The introduction of Dep_kpv74 at the therapeutic dose (10 μg/mouse) or at a 10-fold higher dose did not lead to reliable changes in bloodstream cell content compared with the reference values of intact mice. The biochemical results of the studies indicated that Dep_kpv74 did not exert any toxic effects on liver and kidney functions. …”
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Free fatty acid receptor 2 promotes cardiomyocyte hypertrophy by activating STAT3 and GATA4 by Hui Gao, Kunming Tian, Xiaojun Feng, Mengqing Yan, Chen Gao, Yisheng Jiang, Chenhao Zhu, Huzhe Zhu, Xueping Liu, Yingfu Peng

“…Studies have shown that it is an important way for FAs to exert biological effects through their own receptors besides directly participating biochemical reaction in body. Free fatty acid receptor 2 (FFA2) can be activated by short-chain FAs and is involved in inflammatory reactions and lipid accumulation. …”
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Effects of dietary Bacillus pumilus on the growth, intestinal health, lipid metabolism, and mTOR signaling pathway of juvenile coho salmon (Oncorhynchus kisutch) by Mengjie Guo, Liuqing Meng, Fanghui Li, Yongqiang Liu, Ziqi Zhang, Qin Zhang, Weiguang Kong

“…We then evaluated growth, nutrient metabolism, immune-related serum biochemical markers, enzyme activity, gene expression, and muscle composition. …”
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Isolation and characterization of a novel highly efficient bacterium Lysinibacillus boronitolerans QD4 for quantum dot biosynthesis by Xingyu Gu, Xingyu Gu, Xiaoju Li, Ruijia Zhang, Ruijia Zhang, Ruoli Zheng, Ruoli Zheng, Mingrui Li, Mingrui Li, Rong Huang, Xin Pang

“…Through the physio-biochemical characterization and 16S rRNA-based phylogenetic tree analysis, the strain is identified as Lysinibacillus boronitolerans QD4. …”
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The relationship between anthropometric indices and non-alcoholic fatty liver disease in adults: a cross-sectional study by Mina Radmehr, Reza Homayounfar, Reza Homayounfar, Abolghasem Djazayery

“…General, anthropometric, and dietary assessments were performed using interviews, tools, and valid questionnaires. Biochemical evaluation was also done. Waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), Body mass index (BMI), a body shape index (ABSI), body roundness index (BRI), and visceral fat index (VAI) were also calculated using these measurements and formulas. …”
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Permeability-Enhancing and Protective Effect on Small Intestine of Punicic Acid in Different Forms and Their Nanoemulsions With Low Toxicity by Duan D, Xie H, Jiang J, Yang P, Guo Z, Guo X, Chen X, Yao Q

“…The potential damage on small intestines was assessed by biochemical assay and pathological section.Results: Though the three forms of PA had various strength in enhancing intestinal permeability, the difference was not significant (p > 0.05). …”
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Assessment of Air Pollution Tolerance and Physicochemical Alterations of Alstonia scholaris (L.) R.Br. along Roadsides of Lahore, Pakistan by Zahid Mehmood, Ali Hasnain, Muhammad Luqman, Sohaib Muhammad, Narayan Babu Dhital, Arooba John, Maryam Iqbal, Amna Ejaz, Matiba Tufail, Harma, Hsi-Hsien Yang, Muhammad Umer Farooq Awan

“…Air pollutants also affect the physiological, morphological and biochemical processes in plants such as stomatal function, photosynthesis, respiration, leaf area, chlorophyll content, amino acid, pH and plant growth. …”
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Black Soldier Fly (<i>Hermetia illucens</i>) Larvae as a Protein Substitute in Adverse Food Reactions for Canine Dermatitis: Preliminary Results Among Patients by Nuttawan Srifawattana, Yuthana Phimolsiripol, Pinpanit Boonchuay, Kannika Na-Lampang, Promporn Piboon, Sonthaya Umsumarng, Korakot Nganvongpanit

“…Skin conditions, including dermatological lesions and Pruritus Visual Analog Scale (PVAS) scores, and gastrointestinal signs, including relevant clinical signs, stool consistency, and hematological and biochemical parameters, were monitored. No significant gastrointestinal side effects were observed. …”
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Evaluation of Individual Cardiovascular Risk in Pre-Dialysis CKD Patients by Using the Ratio of Calcium–Phosphorus Product to Estimated Glomerular Filtration Rate (Ca × P/eGFR) by Krasimir Kostov, Tatyana Simeonova, Borislav Ignatov, Tsvetelina Eftimova

“…Methods: Eighty-four CKD patients in stages G1–G4, according to the KDIGO criteria, were classified into CVD (<i>n</i> = 43) and non-CVD (<i>n</i> = 41) groups. Biochemical parameters, including serum creatinine (SCr), blood urea nitrogen (BUN), calcium (Ca), inorganic phosphate (Pi), parathyroid hormone (PTH), alkaline phosphatase (ALP), Ca × P, eGFR, and the Ca × P/eGFR ratio, were measured and calculated. …”
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A Pine Wilt Disease Detection Model Integrated with Mamba Model and Attention Mechanisms Using UAV Imagery by Minhui Bai, Xinyu Di, Lechuan Yu, Jian Ding, Haifeng Lin

“…Manual monitoring, biochemical detection and satellite remote sensing are frequently inadequate for the timely detection and control of pine wilt disease. …”
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Effect Of Exercise Therapy on Lipid Profile and Oxidative Stress Indicators in Patients with Type 2 Diabetes by Madeeha Jadoon, Shazia Zeb, Sajid Razaq, Munazza Khan, Muhammad Shoaib, Sara Mariyum

“…Information was gained through questionnaires, satisfaction surveys, physical assessments, and biochemical assays. Levels of lipid profiles and oxidative stress indicators were determined enzymatically from the sera obtained from the fasting blood samples and by ELISA kits. …”
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Antimicrobial Resistance Patterns of Bacterial Isolates from Blood Culture among HIV/AIDS Patients at Felege Hiwot Referral Hospital, Northwest Ethiopia by Mohabaw Jemal, Teshiwal Deress, Teshome Belachew, Yesuf Adem

“…Identification was performed using colony characteristics and standard biochemical techniques. The antimicrobial susceptibility test was determined by the Kirby–Bauer disc diffusion method. …”
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ucumeropsis mannii seed oil protects against Bisphenol A- induced testicular mitochondrial damages by Patrick Maduabuchi, Aja, Hilary Akobi, Ogwoni, Peter Chinedu, Agu, Ejike Ugbala, Ekpono, Joshua Nonso, Awoke, Oliver Ugochukwu, Ukachi, Obasi Uche, Orji, Boniface Anthony, Ale, Chinonso Peter, Nweke, Esther Ugo, Alum, Darlington C., Chukwu, Christian E., Offor, Atamgba Agbor, Asuk, Ejike, Daniel Eze, Ojochenemi E., Yakubu, J. B., Akob, Onyedika Gabriel, Ani, Chinaza Godswill, Awuchi

“…Remarkably, C. mannii seed oil and bi- sphenol A co-administration significantly reversed the abnormalities observed in the dysregulated biochemical biomarkers. Our findings suggest that C. mannii seed oil has considerable antioxidant potential which can be explored in therapeutic development against systemic toxicity induced by exposure to bisphenol A. …”
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Integrating network analysis and experimental validation to reveal the mechanism of Cuscuta chinensis lam. Extract in the treatment of IgA nephropathy by Xianlong Zhang, Mingjie Liang, Ziyang Lin, Minyi Li, Tingting Duan, Yun Han, Lanqing Meng, Mengqiu Li, Guixuan Lin, Tao Xia, Ying Lai, Boen Liang, Bingqiong Li, Minhua Li, Fengxin Kang, Quan Zhu, Zhenghai Li, Junzheng Yang

“…Sprague-Dawley rats were administered with bovine serum albumin (BSA) with a dose of 800 mg/kg−1 every other day for a period of 12 weeks to obtain IgA nephropathy model. lipopolysaccharide (LPS) was injected through the tail vein at a dose of 0.05 mg at the 6th week, 8th week, and 10th week; 0.1 mL of CCl4 and 0.3 mL of castor oil were injected subcutaneously once a week for 12 weeks; the rats were gavaged with CCLE for 6 weeks from 13th week. Biochemical analysis, tGFR analysis, enzyme-linked immunosorbent assay (ELISA) analysis, periodic acid-Schiff (PAS) staining, Masson staining, and immunofluorescence staining were employed to evaluate the impact of CCLE on IgA nephropathy in rat. …”
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Steatotic liver disease in people with HIV at Tshepong Hospital: A post-mortem analysis by Aqeela Moosa, Ebrahim Variava, Alistair D. Calver, Gajendra Chita, Nadia Sabet, Sharol Ngwenya, Maria Papathanasopoulos, Tanvier Omar

“…Method: We conducted a retrospective cross-sectional study in which liver histology from 59 deceased people who were infected with HIV was assessed for steatosis, and findings correlated with clinical, epidemiological, and biochemical data. Results: Decedents were predominantly men (33/59); 63% (37/59) were virologically supressed. …”
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Correlation between Neutrophil Gelatinase Associated with Lipocaline and Beta-2 Microglobulin with Other Renal Markers in Iraqi Patients with Multiple Myeloma by Inas Nazeeh Abed, Usama Salman Al-timari, Hiba Abid Al-Hussein hassan, Abbas Thamer Dwayyikh

“…Multiple myeloma disease was diagnosed using symptoms, biochemical testing, x-ray, and clinical examination by specialists. …”
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Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…All patients underwent following investigation: physical examination, filling of nutrition diary, CAGE and AUDIT questionnaires, taking occupational history, anthopometrical examination, US of abdominal organs, clinical and biochemical blood tests, assessment of HCVAb and HBsAg. …”
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Evaluation of the rainfed and irrigated conditions on biomass and essential oil yield of German chamomile (Matricaria chamomilla) in response to melatonin foliar application by Hossein Gorgini Shabankareh, Mohammad Reza Asgharipour, Ali Salehi Sardoei, Ahmad Reza Kamaliun, Hamid Mohammadi, Mansour Ghorbanpour

“…Based on these findings, combining rainfed cultivation with melatonin application is a promising and environmentally friendly strategy to enhance drought tolerance, growth, and biochemical content in German chamomile.…”
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Association of anthropometric and obesity indices with abnormal blood lipid levels in young and middle-aged adults by Xiaoling Zhou, Zuoli Zou, Ying Liu, Yuzhong Yan, Jing Wu, Geyao Zhou, Ming Li

“…Methods: From July to November 2022, we distributed health survey questionnaires to the target population in the hospital and collected their biochemical and anthropometric data. Multivariate regression models and Receiver operating characteristic (ROC) curve analysis were used for data analyzing. …”
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