Circulating Interleukin-6 (but Not Other Immune Mediators) Associates with Criteria for Fried’s Frailty among Very Old Adults by Gilberto Santos Morais Junior, Diego Ignacio Valenzuela Perez, Audrey Cecília Tonet-Furioso, Lucy Gomes, Karla Helena Coelho Vilaça, Vicente Paulo Alves, Clayton Franco Moraes, Otávio Toledo Nóbrega

“…One hundred and sixty-one very old patients (aged ≥80 years) devoid of cognitive decline were eligible for analyses. Clinical and biochemical data along with physical and cognitive assessments encompassing dual-energy X-ray scans and hand dynamometry were adopted to investigate frailty criteria, while circulating immune mediators (IFNγ, IL-2, IL-4, IL-6, IL-10, and TNFα) were assessed using high-throughput flow cytometry. …”
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Acute and prolonged toxicity assessment of Cannabis sativa extract in rodents and lagomorphs by Alana C. Costa, Arquimedes Gasparotto, Jr., Alana A.K. Garcia, Cícero A.C. Pereira, Emerson L.B. Lourenço, Helena P.G. Joaquim

“…Although liver enzymes were elevated at the highest doses, other biochemical and hematological parameters remained unchanged. …”
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Two Cysteines in Raf Kinase Inhibitor Protein Make Differential Contributions to Structural Dynamics In Vitro by Hyun Sang Cho, Mohammad Faysal Al Mazid, Eun-Young Lee, Md Abu Rayhan, Hyoun Sook Kim, Byung Il Lee, Hye Jin You

“…Mutation of alanine or serine instead of cysteine in RKIP proteins did not affect the biochemical characteristics, while dynamic light scattering and liquid chromatography (LC) quadrupole time-of-flight (Q-TOF) mass spectrometry (MS) suggested distinct peaks in solution, which were identified via LC–MS/MS analyses, and further clarified the role of cysteine in RKIP dimerization. rhRKIP dimer formation was abrogated by a 32-aa peptide mimicking the region between two RKIP proteins for dimerization. …”
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Hypoglycemic Effects and Myocardial Protection of Sanghuangporus vaninii Polysaccharide on Diabetes Rats by Yue CHANG, Yue WU, Jianfeng GUO, Weiyuan ZHAO, Yuantian LU, Di LIU

“…Following 4 weeks of continuous intervention by gavage, the weights and multiple physiological and biochemical indicators of rats were measured and recorded, and performed pathological observations of the pancreatic and myocardial tissues of rats. …”
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The Calicophoron daubneyi genome provides new insight into mechanisms of feeding, eggshell synthesis and parasite-microbe interactions by Shauna M. Clancy, Mark Whitehead, Nicola A. M. Oliver, Kathryn M. Huson, Jake Kyle, Daniel Demartini, Allister Irvine, Fernanda Godoy Santos, Paul-Emile Kajugu, Robert E. B. Hanna, Sharon A. Huws, Russell M. Morphew, J. Herbert Waite, Sam Haldenby, Mark W. Robinson

“…Finally, although extracellular digestion of rumen ciliates occurs within the C. daubneyi gut, unique ultrastructural and biochemical adaptations of the gastrodermal cells suggest that adult flukes also acquire nutrients via uptake of volatile fatty acids from rumen fluid. …”
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Melatonin Enhances Maize Germination, Growth, and Salt Tolerance by Regulating Reactive Oxygen Species Accumulation and Antioxidant Systems by Wei-Qing Li, Jia-Yu Li, Shao-Jie Bi, Jia-Yue Jin, Zhong-Ling Fan, Zi-Lin Shang, Yi-Fei Zhang, Yan-Jie Wang

“…Melatonin (MT) is a crucial hormone that controls and positively regulates plant growth under abiotic stress, but the biochemical and physiological processes of the combination of melatonin seed initiation and exogenous spray treatments and their effects on maize germination and seedling salt tolerance are not well understood. …”
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Characterization and structural analysis of a versatile aromatic prenyltransferase for imidazole-containing diketopiperazines by Wenxue Wang, Peng Wang, Chuanteng Ma, Kang Li, Zian Wang, Yuting Liu, Lu Wang, Guojian Zhang, Qian Che, Tianjiao Zhu, Yuzhong Zhang, Dehai Li

“…Here, we discover a dimethylallyl tryptophan synthase family prenyltransferase, AuraA, that catalyzes the rare dimethylallylation on the imidazole moiety in the biosynthesis of aurantiamine. Biochemical assays validate that AuraA could accept both cyclo-(L-Val-L-His) and cyclo-(L-Val-DH-His) as substrates, while the prenylation modes are completely different, yielding C2-regular and C5-reverse products, respectively. …”
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Viscosol Treatment Ameliorates Insulin-Mediated Regulation of Dyslipidemia, Hepatic Steatosis, and Lipid Metabolism by Targeting PTP1B in Type-2 Diabetic Mice Model by Idrees Raza, Aamir Sohail, Hamza Muneer, Hajra Fayyaz, Zia Uddin, Amany I. Almars, Waheeb S. Aggad, Hailah M. Almohaimeed, Imran Ullah

“…We found the retrieval of normal morphology of adipocytes and hepatocytes in the compound-treated group. The biochemical parameters showed the gradual reduction of LDL, VLDL, TC, and TG in the serum of the compound-treated group. …”
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Prediction models of iron level in beef muscle tissue toward ecological well-being by K. Narozhnykh

“…BACKGROUND AND OBJECTIVES: Elemental status is associated with the biochemical processes occurring in the body. Beef, consumed worldwide, is an excellent source of iron in terms of quantity and bioavailability, providing up to 18 percent of the daily requirement. …”
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Comprehensive review of mapping climate change impacts on tea cultivation: bibliometric and content analysis of trends, influences, adaptation strategies, and future directions by Altyeb Ali Abaker Omer, Altyeb Ali Abaker Omer, Chun-Hua Zhang, Chun-Hua Zhang, Jie Liu, Jie Liu, Zhi-guo Shan, Zhi-guo Shan

“…The results show significant progress in understanding the physiological, biochemical, and molecular responses of tea plants to climate-induced stressors, including antioxidant mechanisms, secondary metabolite regulation, and genomic adaptations. …”
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Comprehensive multi-omics, behavioral and morphological analysis of the hazards of nano-plastics in mice with internal carotid artery occlusion by Lu Wang, Jia-Qi Ma, Li-Jia Song, Xiao-Peng Qu, Yue Zhang, Hai-Ming Fan, Chao Wang, Long-Long Zheng, Guo-Dong Gao, Yan Qu, Liang-Liang Shen, Bei Liu

“…The findings helped explain the differences in the underlying biochemical responses at the microscopic level in mice after NP exposure. …”
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Assessing clenbuterol’s modulation of metabolic and inflammatory pathways in Nile tilapia (Oreochromas niloticous) fed high fat diet by Aya G. Rashwan, Doaa H. Assar, Abdallah S. Salah, Muyassar H. Abualreesh, Shimaa M. R. Salem, Norah Althobaiti, Zizy I. Elbialy

“…Abstract This study was performed to reveal the metabolic effects and molecular mechanisms that govern the dietary incorporation of clenbuterol on growth performance, haemato-biochemical changes, histological alteration, and gene expression regulating glucose and lipid metabolism in normal and high-fat diets fed in Nile tilapia (Oreochromis niloticus). …”
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Cardiovascular Risk and Metabolic Syndrome Characteristics in Patients with Nonfunctional Pituitary Macroadenoma by Guadalupe Vargas-Ortega, Baldomero González-Virla, Lourdes Balcázar-Hernández, Oriana Nieto-Guzmán, Ana Pamela Garrido-Mendoza, Marco Antonio Flores-Maya, Victoria Mendoza-Zubieta

“…Prevalence of diabetes, hypertension, high cholesterol, obesity, and cardiovascular risk and its relationship with the clinical and biochemical characteristics. Results. The prevalence of diabetes, hypertension, high cholesterol, and obesity at diagnosis was 30%, 27%, 48%, and 85% and did not change upon the last visit. …”
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Pharmacogenetics: Influence of CYP2C9*2 and *3 alleles polymorphisms on Iraqi type 2 diabetic patients by Ghada S. Rasool, Asmaa A. Hussien, Suhad R. Al-Tayie, Salwa J. Al-Awadi, Hussein OM Al-Dahmoshi

“…Fasting serum glucose, fasting insulin, and glycated hemoglobin (HbA1c) levels were measured as part of the biochemical analysis. Results: The CYP2C9 gene variants were analyzed in a study group. …”
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Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins by Stella W. L. Milferstaedt, Marie Joest, Lennard L. Bohlender, Sebastian N. W. Hoernstein, Buğra Özdemir, Eva L. Decker, Chris van der Does, Ralf Reski

“…FtsZ proteins are GTPases sharing structural and biochemical similarities with eukaryotic tubulin. In the moss Physcomitrella, the morphology of the FtsZ polymer networks varies between the different FtsZ isoforms. …”
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Dietary Fiber-Rich <i>Spartina anglica</i> Improves Intestinal Health and Antioxidant Capacity of Zhedong White Geese by Xiao Zhou, Li Wang, Jiuli Dai, Huiyan Jia, Kai Shi, Jian Zhao, Shufang Chen

“…SA supplementation did not significantly influence serum biochemical parameters or organ indices but increased cecum length (<i>p</i> < 0.05). …”
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Association between obstructive sleep apnea and hyperuricemia/gout in the general population: a cross-sectional study by Suyeon Park, Seong-Hyeok Bak, Hyun-Sook Kim, Kyung-Ann Lee

“…Anthropometric, socioeconomic, health-related variables, and biochemical measurements, including serum uric acid (SUA) levels, were included in the analysis. …”
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Mechanistic insights into Y-Box binding protein-1 mediated regulation of lipid metabolism and oxidative stress in NAFLD via INHBE/TNF-β pathway by Zhi Ren, Rui Wang, Jun Wei, Zhenzeng Ma, Xiquan Ke

“…Quantitative real-time PCR (QRT-PCR), Western blotting, flow cytometry, and various biochemical assays were used to evaluate gene expression, lipid accumulation, and oxidative stress. …”
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Integrating Metabolomics and Genomics to Uncover the Impact of Fermented Total Mixed Ration on Heifer Growth Performance Through Host-Dependent Metabolic Pathways by Zhenzhen Hu, Minyu Zuo, Shixuan Ding, Yifan Zhong, Mingyuan Xue, Huichao Zheng

“…At the end of trial, blood and urine samples were collected to measure biochemical indexes and metabolomics. The results showed that high rice straw content and ZF diets could increase blood glucose and non-protein nitrogen in heifers, that is, blood glucose and urea nitrogen levels in HSF and ZF groups were higher than those in LSF and MSF groups (<i>p</i> < 0.05). …”
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Risk Factors for Cognitive Impairment in Patients with Type 2 Diabetes by Lin Sun, Xue Diao, Xiaokun Gang, You Lv, Xue Zhao, Shuo Yang, Ying Gao, Guixia Wang

“…Data regarding demographic characteristics, clinical features of diabetes, biochemical markers, and metabolomics were collected. …”
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