SYNERGISTIC EFFECT OF QUERCETIN AND EPIGALLOCATECHIN-3-GALLATE AS AGENTS TO PREVENT CONNECTIVE TISSUE DISINTEGRATION IN THE PERIODONTIUM OF RATS UNDER SYSTEMIC AND LOCAL ADMINISTR... by A.M. Yelins’ka, V.O. Kostenko

“…The aim of the present study was to investigate the co-effect produced by water-soluble form of quercetin and epigallocatechin-3-gallate (EGCG) on biochemical markers of periodontal organic matrix depolimerization under systemic administration and local application of S. typhi lipopolisaccharide (LPS). …”
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Molecular Detection and Multidrug Resistance of Shigella spp. Isolated from Wild Waterfowl and Migratory Birds in Bangladesh by Jarna Karmoker, Md. Saiful Islam, Md. Liton Rana, Md. Ashek Ullah, Fahim Haque Neloy, Nahian Muniath Oishy, Pritom Kumar Pramanik, Mahbubul Pratik Siddique, Sukumar Saha, Md. Tanvir Rahman

“…Shigella spp. were isolated and identified by culturing, staining, and biochemical tests followed by polymerase chain reaction (PCR). …”
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Anthocyanins as functional food components by R. S. Yudina, E. I. Gordeeva, O. Yu. Shoeva, M. A. Tikhonova, E. K. Khlestkina

“…To date, the structure and functions of anthocyanins in plant cells have been well studied, and the pathway of their biosynthesis is one of the most fully characterized pathways of secondary metabolite biosynthesis at both the biochemical and genetic levels. Along with these fundamental achievements, we are beginning to realize the potential of anthocyanins as compounds of industrial importance, as pigments themselves, as well as components of functional food that contribute to the prevention and reduction of risk of chronic diseases. …”
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PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways by Jordi Camps, Anabel García-Heredia, Anna Rull, Carlos Alonso-Villaverde, Gerard Aragonès, Raúl Beltrán-Debón, Esther Rodríguez-Gallego, Jorge Joven

“…Recent evidence suggests that PON1 and the monocyte chemoattractant protein-1 (MCP-1) are involved in coordinating the inflammatory response in damaged tissues; PPAR may be central in the regulation of these biochemical pathways. This article reviews the state of knowledge on PON1 biochemistry and function, the influence of genetic variation, and the regulation of PON1 expression by pharmaceutical compounds that increase PPAR activity. …”
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In Vitro Induction of Hypertrophic Chondrocyte Differentiation of Naïve MSCs by Strain by Thomas Jörimann, Priscilla Füllemann, Anita Jose, Romano Matthys, Esther Wehrle, Martin J. Stoddart, Sophie Verrier

“…This suggests that, under mechanical strain, hypertrophic differentiation is hindered by TGFβ1, while chondrogenesis is promoted. Biochemical analyses further confirmed these findings. …”
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β-Glucan-modified nanoparticles with different particle sizes exhibit different lymphatic targeting efficiencies and adjuvant effects by Wen Guo, Xinyue Zhang, Long Wan, Zhiqi Wang, Meiqi Han, Ziwei Yan, Jia Li, Ruizhu Deng, Shenglong Li, Yuling Mao, Siling Wang

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Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model by Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi

“…After 12 weeks, blood samples and the liver were collected for biochemical analysis. Results. The induction of prediabetes resulted in increased release of liver enzymes (AST and ALT), increased liver glycogen and triglyceride, lipid peroxidation, and decreased sterol regulatory element-binding protein (SREBP1c) and antioxidant enzymes. …”
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Comparative Evaluation of Salt Tolerance in Four Self-Rooted Hazelnut (<i>Corylus avellana</i> L. and <i>Corylus americana</i> Walter) Cultivars by Xavier Rius-Garcia, María Videgain-Marco, José Casanova-Gascón, Luis Acuña-Rello, Pablo Martín-Ramos

“…This research assessed their morphological, physiological, and biochemical responses through an analysis of their growth parameters, photosynthetic efficiency, visual symptoms, and ion content. …”
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Antimicrobial Usage by Small-Scale Commercial Poultry Farmers in Mid-Western District of Masindi Uganda: Patterns, Public Health Implications, and Antimicrobial Resistance of E. co... by Majalija Samuel, Tony Fredrick Wabwire, Gabriel Tumwine, Peter Waiswa

“…Fecal swabs from chickens were inoculated onto a MacConkey agar, and E. coli was confirmed by standard biochemical tests. Antimicrobial susceptibility was determined by the disk diffusion method for 7 antibiotics. …”
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Impact of geographical variation on nutritional and antioxidant properties of Basella alba L. from Sri Lanka by Lakshanee Weerasinghe Dahanayaka, Mapa Mudiyanselage Sumudu Tharangani Mapa, Chamila Chathuranga Kadigamuwa, Dhanushka Udayanga

“…Cluster analysis categorized samples into four groups, linking biochemical traits to agro-climatic zones. The principal component analysis and cluster analysis showed a close relationship between some locations due to their high antioxidant and phytochemical accumulation. …”
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Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer by Sangavi Eswaran, Samatha Bhat, Dinesh Upadhya, Roshan Mascarenhas, Shama Prasada Kabekkodu

“…DOC2B-SiHa and vector-SiHa EVs were co-incubated separately with recipient cell and subjected to various cellular and biochemical experiments. For the first time, we demonstrated that DOC2B localizes to EVs, and its transfer to EV may require intracellular calcium. …”
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Development of therapeutic supplement using roasted-cashew-nut to protect cerebral vasoconstriction injury triggered by mixture of petroleum hydrocarbons in the hypothalamus and hi... by J.K. Akintunde, V.O. Akomolafe, R.N. Ugbaja, A.M. Olude, A.D. Folayan

“…Cell pathological evaluation was done using hematoxylin and eosin staining and visualized under the microscope. Biochemical and molecular markers of brain vasoconstriction injury (BVI) were evaluated using spectrophotometer and RT-PCR analyzer, respectively. …”
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Comparison of Perinatal, Newborn, and Audiometry Results of COVID-19 Pregnant Women by Mehmet Yilmaz, Şerif Aksin, Deniz Balsak, Fazil Avci, Osman Özdoğru, Bekir Helvacıoğlu, Mahmut Erdemoğlu, Yasemin Aboalhasan, Gülsüm Doğan

“…In general, gestational week, age, parity, biochemical parameters, duration of hospital stay, week of delivery, fetal weight, and apgar scores were compared between pregnant women with COVID-19 and normal. …”
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Occurrence and Determination of Antimicrobial Resistant Escherichia coli Isolates in Fish and Vegetables as Indicator Organism of Faecal Contamination in Dar es Salaam, Tanzania by Francis Mwanza, Erick Vitus Gabriel Komba, Dominic Mukama Kambarage

“…Confirmed isolates on biochemical tests were tested for resistance against six antibiotics using the disc diffusion method. …”
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The Role of Nutrition Across Production Stages to Improve Sow Longevity by Matheus Saliba Monteiro, Rafaella Fernandes Carnevale, Bruno Bracco Donatelli Muro, Ana Lígia Braga Mezzina, Bruno Braga Carnino, André Pegoraro Poor, Carlos Emilio Cabrera Matajira, Cesar Augusto Pospissil Garbossa

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Association of Serum Melatonin Level with Mild Cognitive Impairment in Type 2 Diabetic Patients: A Cross-Sectional Study by Jichen Zhang, Jiancan Lu, Hongling Zhu, Xinglu Zhou, Xijuan Wei, Mingjun Gu

“…Their blood sample was examined for the level of melatonin and other biochemical parameters. Results. Melatonin concentration was decreased in MCI patients to non-MCI patients (P < 0.001). …”
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Peptide Design for Enhanced Anti-Melanogenesis: Optimizing Molecular Weight, Polarity, and Cyclization by Putri SA, Maharani R, Maksum IP, Siahaan TJ

“…Selvi Apriliana Putri,1 Rani Maharani,1 Iman Permana Maksum,1 Teruna J Siahaan2 1Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Bandung, 40173, Indonesia; 2Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USACorrespondence: Iman Permana Maksum, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Bandung, 40173, Indonesia, Email iman.permana@unpad.ac.idAbstract: Melanogenesis is a biochemical process that regulates skin pigmentation, which is crucial role in protecting against ultraviolet radiation. …”
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Dichotomitin promotes osteoblast differentiation and improves osteoporosis by inhibiting oxidative stress by Meichun Han, Weibin Du, Lei Zhang, Zhenwei Wang, Shengqiang Fang, Yang Zheng, Renfu Quan

“…Micro-CT evaluated the femoral, while histological examination assessed tibial tissues. Serum osteogenic biochemical markers were measured. In vitro, osteogenic differentiation was induced with varying concentrations of DH, followed by ALP and ARS staining. …”
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Significance of siderophore-producing cyanobacteria on enhancing iron uptake potentiality of maize plants grown under iron-deficiency by Mandees Bakr Brick, Mervat H. Hussein, Amr M. Mowafy, Ragaa A. Hamouda, Amr M. Ayyad, Dina A. Refaay

“…Abstract Background In response to iron deficiency and other environmental stressors, cyanobacteria producing siderophores can help in ameliorating plant stress and enhancing growth physiological and biochemical processes. The objective of this work was to screen the potential of Arthrospira platensis, Pseudanabaena limnetica, Nostoc carneum, and Synechococcus mundulus for siderophore production to select the most promising isolate, then to examine the potentiality of the isolated siderophore in promoting Zea mays seedling growth in an iron-limited environment. …”
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Developing novel Lin28 inhibitors by computer aided drug design by Victor M. Matias-Barrios, Mariia Radaeva, Graciella Rosellinny, Qiongqiong Jia, Ning Xie, Monica Villanueva, Hanadi Ibrahim, Jason Smith, Martin Gleave, Nada Lallous, Suzana K. Straus, Artem Cherkasov, Xuesen Dong

“…In this contribution, we applied computer-aided drug design (CADD) in combination with quantitative biochemical and biological assays. These efforts led to the discovery of Ln268 as a drug candidate that can block Lin28 from binding to its RNA substrates and inhibit Lin28 activities. …”
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