Smoking cessation is a protective factor for lung cancer onset and mortality: a population-based prospective cohort study by Wei Yin, Zhuochen Lin, Wei-Jie Gong, Wen-Xuan Wang, Ying-Ying Zhu, Yi-Lin Fu, Han Yang, Jin-Xin Zhang, Peng Lin, Ji-Bin Li

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A generative model for evaluating missing data methods in large epidemiological cohorts by Lav Radosavljević, Stephen M. Smith, Thomas E. Nichols

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Distinctive blood and salivary proteomics signatures in Qatari individuals at high risk for cardiovascular disease by Ghada Yousif, Selvasankar Murugesan, Mohamed Nadhir Djekidel, Annalisa Terranegra, Giusy Gentilcore, Jean Charles Grivel, Souhaila Al Khodor

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Association between triglyceride-glucose (TyG) related indices and cardiovascular diseases and mortality among individuals with metabolic dysfunction-associated steatotic liver disease: a cohort study of UK Biobank by Yanan Qiao, Yue Wang, Cheng Chen, Yueqing Huang, Chunhua Zhao

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Association between major depressive disorder or depressive symptoms and the risk of vascular complications among patients with type 2 diabetes, and the mediating role of metabolic biomarkers: an analysis of the UK Biobank cohortResearch in context by Guochen Li, Yongfu Yu, Chunqing Lin, Shichen Zheng, Hong Tu, Wanghong Xu

“…Findings: Of the total 23,856 patients with T2DM in the UK Biobank, 13,706 participants (61% males) were eligible and included in this study. …”
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Beverage consumption modifies the risk of type 2 diabetes associated with ambient air pollution exposure by Chaonan Fan, Wenjuan Wang, Wenxue Xiong, Zhiyao Li, Li Ling

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Future risk of falls induced by ankle-foot sprains history: An observational and mendelian randomization study by Xiao'ao Xue, Weichu Tao, Qianru Li, Yi Li, Yiran Wang, Le Yu, Xicheng Gu, Tian Xia, Rong Lu, Ru Wang, He Wang, Yinghui Hua

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Multi-modal characterisation of early-stage, subclinical cardiac deterioration in patients with type 2 diabetes by Ambre Bertrand, Andrew Lewis, Julia Camps, Vicente Grau, Blanca Rodriguez

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A novel framework for assessing causal effect of microbiome on health: long-term antibiotic usage as an instrument by Nele Taba, Krista Fischer, Estonian Biobank Research Team, Elin Org, Oliver Aasmets

“…We apply the AB-IVR method on the Estonian Biobank data and show that the microbiome has a causal role in numerous diseases including migraine, depression and irritable bowel syndrome. …”
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SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection by Richard C. Crist, Samar N. Chehimi, Saurabh S. Divakaran, Michael J. Montague, Sébastien Tremblay, Noah Snyder-Mackler, Martin O. Bohlen, Kenneth L. Chiou, Trish M. Zintel, Cayo Biobank Research Unit, Michael L. Platt, Halvor Juul, Guido Silvestri, Matthew R. Hayes, Dennis L. Kolson, Benjamin C. Reiner

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Risk factors affecting polygenic score performance across diverse cohorts by Daniel Hui, Scott Dudek, Krzysztof Kiryluk, Theresa L Walunas, Iftikhar J Kullo, Wei-Qi Wei, Hemant Tiwari, Josh F Peterson, Wendy K Chung, Brittney H Davis, Atlas Khan, Leah C Kottyan, Nita A Limdi, Qiping Feng, Megan J Puckelwartz, Chunhua Weng, Johanna L Smith, Elizabeth W Karlson, Regeneron Genetics Center, Penn Medicine BioBank, Gail P Jarvik, Marylyn D Ritchie

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Human Papillomavirus and Coronary Artery Disease in Climacteric Women: Is There an Association? by Luciane Maria Oliveira Brito, Haissa Oliveira Brito, Rita da Graça Carvalhal Frazão Corrêa, Clariano Pires de Oliveira Neto, Joyce Pinheiro Leal Costa, Sally Cristina Moutinho Monteiro, Flávia Castello Branco Vidal, Maria do Desterro Soares Brandão Nascimento, José Albuquerque de Figueiredo Neto, Rui Miguel Gil da Costa, Leonardo Victor Galvão-Moreira, Ismael Dale Cotrim Guerreiro da Silva

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Multi-omics analysis reveals the interplay between intratumoral bacteria and glioma by Ting Li, Zhanyi Zhao, Meichang Peng, Lu Zhang, Cheng Wang, Feiyang Luo, Meiqin Zeng, Kaijian Sun, Zhencheng Fang, Yunhao Luo, Yugu Xie, Cui Lv, Jiaxuan Wang, Jian-Dong Huang, Hongwei Zhou, Haitao Sun

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Rapid Detection of the mt3243A > G Mutation Using Urine Sediment in Elderly Chinese Type 2 Diabetic Patients by Yinan Zhang, Xiujuan Du, Xinqian Geng, Chen Chu, Huijuan Lu, Yixie Shen, Ruihua Chen, Pingyan Fang, Yanmei Feng, Xiaojie Zhang, Yan Chen, Yanping Zhou, Congrong Wang, Weiping Jia

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De Novo Mutation of m.3243A>G together with m.16093T>C Associated with Atypical Clinical Features in a Pedigree with MIDD Syndrome by Zhixin Jiang, Yinan Zhang, Jingbin Yan, Fengwen Li, Xinqian Geng, Huijuan Lu, Xiaoer Wei, Yanmei Feng, Congrong Wang, Weiping Jia

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Gene Expression Differences Predict Treatment Outcome of Merkel Cell Carcinoma Patients by Loren Masterson, Bryan J. Thibodeau, Laura E. Fortier, Timothy J. Geddes, Barbara L. Pruetz, Rajwant Malhotra, Richard Keidan, George D. Wilson

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Dental problems and oral microbiome alterations in ulcerative colitis by Robert Kucharski, Robert Kucharski, Bartosz Kamil Sobocki, Ewa Stachowska, Nikola Bulman, Leszek Kalinowski, Leszek Kalinowski, Karolina Kaźmierczak-Siedlecka

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The causal association of cheese intake with type 2 diabetes mellitus: results from a two-sample Mendelian randomization study by Tao Zhong, Yu-qing Huang, Guiming Wang

“…Material and methods Summary cheese intake statistics were obtained from UK Biobank and publicly available genome-wide association studies (GWAS) for type 2 diabetes from IEU OpenGWAS, FinnGen Biobank, EBI GWAS, and Biobank Japan. …”
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Associations between changes in the gut microbiota and liver cirrhosis: a systematic review and meta-analysis by Ye Liu, Ziwei Chen, Chang Li, Tianhan Sun, Xuanmei Luo, Boyue Jiang, Meilan Liu, Qing Wang, Tong Li, Jianfu Cao, Yayu Li, Yuan Chen, Lu Kuai, Fei Xiao, Hongtao Xu, Hongyuan Cui

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Causal linkage between adult height and kidney function: An integrated population-scale observational analysis and Mendelian randomization study. by Sehoon Park, Soojin Lee, Yaerim Kim, Yeonhee Lee, Min Woo Kang, Kwangsoo Kim, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim

“…In addition, similar results were obtained by two-sample MR of eGFRcystatinC (adjusted beta -1.303, standard error 0.140, P < 0.001) and CKDcystatinC (adjusted beta 0.153, standard error 0.025, P < 0.001) in UK Biobank. In conclusion, the results of this study suggest that a taller adult height is causally linked to worse kidney function in middle-aged to elderly individuals, independent of the effect of body mass index.…”
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