Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts by Shadrack Donkor, Christopher Larbie, Gustav Komlaga, Benjamin Obukowho Emikpe

“…Hepatoprotective efficacy was assessed by assaying serum biochemical markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (γGT), bilirubin (Bil), antioxidative biomarkers including reduced glutathione (GSH), glutathione peroxidase (GPx), glutathione transferase (GST), superoxide dismutase (SOD), malondialdehyde (MDA), hydrogen peroxidase (H202), and nitric oxide (NO), as well as histological observations. …”
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Impairment of Hepatic and Renal Functions by 2,5-Hexanedione Is Accompanied by Oxidative Stress in Rats by Isaac A. Adedara, Amos O. Abolaji, Blessing E. Odion, Isioma J. Okwudi, Abiola A. Omoloja, Ebenezer O. Farombi

“…Exposure to 2,5-HD caused liver and kidney atrophy evidenced by significant elevation in serum aminotransferases, alkaline phosphatase, albumin, bilirubin, urea, creatinine, and electrolytes levels compared with control. …”
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Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study by Arthur Clement, Lee S Nguyen, Anousone Daulasim, Magali Souibri

“…We aimed to confirm the accuracy of troponin, analysed as time-dependent variable, to predict mortality independently from other biomarkers; and to assess the incidence and prognosis of a 10 times upper normal value threshold (troponin10N) used in the current fourth definition of myocardial infarction.Methods In a prospective cohort of patients who underwent cardiopulmonary bypass cardiac procedures, we assessed the association between serum levels of troponin, creatinine, bilirubin, serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), C-reactive protein (CRP), lactate and in-hospital mortality. …”
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Association between red blood cell distribution width-to-albumin ratio at admission and all-cause mortality in patients with acute pancreatitis based on the MIMIC-III database. by Qingsong Wu, Lianyi Liao, Qingjun Deng

“…Multivariate analysis indicated that potassium levels, total bilirubin, blood urea nitrogen, lactate, partial thromboplastin time, neutrophil and RAR were independently associated with the 28-day mortality. …”
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A Novel Use of Early Radiation Therapy in the Treatment of Hyperbilirubinemia in a Patient with Primary Hepatic Lymphoma and Chronic Hepatitis C by Venkata S. Tammana, Rehana Begum, Patricia Oneal, Hemamalini Karpurapu, Amruta Muley, Sri Lakshmi Hyndavi Yeruva, Jacquelyn Dunmore-Griffith, Eyasu Mekonen, Nabhani Hasan

“…Hence, radiation therapy was given initially to reduce his bilirubin levels and tumor size. The patient was able to complete six cycles of rituximab combined with cyclophosphamide, adriamycin, vincristine, and prednisone (R-CHOP) chemotherapy and achieved a complete response verified by positron emission tomography-computed tomography (PET-CT). …”
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Tuberkulosis Milier dan HIV-AIDS dengan Drug-induced Hepatitis by Hans Wincen W, Zulkarnain Arsyad, Fauzar Fauzar

“…Dari pemeriksaan laboratorium didapatkan nilai SGPT 137 u/L dan SGOT 84 u/L, bilirubin urin (+), Ig M anti HAV negatif, HBsAg non reaktif, Anti HCV 0,09 (<1), rontgen thorak ditemukan kesan TB milier, USG Abdomen kesan hepatitis. …”
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Tacrolimus and mycophenolate mofetil in corticosteroid-resistant hepatitis secondary to tislelizumab: a case report by Chang Jiang, Shanxian Guo

“…Three weeks after the fourth treatment cycle, the patient experienced symptoms, such as decreased appetite, itching, yellow urine, and jaundice, and was diagnosed with IRH, manifested as “Grade 3 total bilirubin increase,” “Grade 3 alanine transaminase increase,” and “Grade 3 aspartate transaminase increase.” …”
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EFFICACY OF THIONONTRITE-S FOR PREVENTION OF METABOLIC LIVER DISEASE IN CATTLE by Ye. V. Tyapkina, M. P. Semenenko, Ye. V.  Kuzminova, A. A.  Abramov

“…The positive effect of thionontrite-S was also observed with regard to pigment metabolism; the concentration of total bilirubin in the experimental group was within physiological limits (4.28 ± 0.55 µM/l), whereas in the control group hyperbilirubinemia was 1.6 times higher than the upper limit of normal. …”
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Shigella sonnei Bacteremia Presenting with Profound Hepatic Dysfunction by Oluwaseun Shogbesan, Andrew Rettew, Bilal Shaikh, Abdullateef Abdulkareem, Anthony Donato

“….), normal alkaline phosphatase, elevated total and direct bilirubin of 8.2 mg/dL and 4.4 mg/dL, albumin of 3.2 g/dL, INR of 2.9, prothrombin time of 31.7, and platelet of 96,000/μL. …”
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Hepatoprotective Effects of Crude Stem Bark Extracts and Solvent Fractions of Cordia africana against Acetaminophen-Induced Liver Injury in Rats by Gudeta Duga Geresu, Shemsu Umer, Mahlet Arayaselassie, Genet Ashebir, Eyasu Makonnen

“…Serum levels of the liver enzymes and total bilirubin (TB), as well as lipid profiles, were determined. …”
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Alpha-Fetoprotein as a Predictive Marker for Patients with Hepatitis B-Related Acute-on-Chronic Liver Failure by Xiaoping Wang, Caifei Shen, Jianjiang Yang, Xianjun Yang, Sen Qin, Haijun Zeng, Xiaoling Wu, Shanhong Tang, Weizheng Zeng

“…Age (HR 1.041), total bilirubin (HR 1.004), log10AFP⁡  (HR 2.155), and INR (HR 1.446) were found to be risk factors of survival. …”
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Development and validation of a machine learning-based prediction model for hepatorenal syndrome in liver cirrhosis patients using MIMIC-IV and eICU databases by Fengwei Yao, Ji Luo, Qian Zhou, Luhua Wang, Zhijun He

“…The final predictive model, based on five key variables—spontaneous bacterial peritonitis, red blood cell count, creatinine, activated partial thromboplastin time, and total bilirubin—showed excellent discrimination, with AUCs of 0.832 (95% CI 0.8069–0.8563) in the training set and 0.8415 (95% CI 0.8042–0.8789) in the validation set. …”
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Glucose-6-phosphate dehydrogenase deficiency with coinherited Gaucher disease: A rare association by Nupur Parakh, Kusha Sharma, Sunita Sharma, Priti Chatterjee, Varinder Singh

“…Peripheral smear showed predominantly microcytic hypochromic anemia with moderate degree of anisocytosis, many nucleated red blood cells, few schistocytes, polychromatophils and corrected reticulocyte count 7.89%. S. Bilirubin was 1.1 mg/dL. Hb high-performance liquid chromatography (HPLC) of the child and his parents was within normal limit. …”
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Mesenchymal Stem Cells Pretreated with HGF and FGF4 Can Reduce Liver Fibrosis in Mice by Sulaiman Shams, Sadia Mohsin, Ghazanfar Ali Nasir, Mohsin Khan, Shaheen N. Khan

“…In vivo data in cytokines pretreated group demonstrated greater homing of MSCs in liver, restored glycogen storage, and significant reduction in collagen, alkaline phosphatase, and bilirubin levels. TUNEL assay and real time PCR also supported our hypothesis. …”
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Improved Outcome of Biliary Atresia with Postoperative High-Dose Steroid by Rui Dong, Zai Song, Gong Chen, Shan Zheng, Xian-min Xiao

“…Intravenous prednisolone administration was started 1 week after surgery, followed by 8 to 12 weeks of oral prednisolone. Total bilirubin (TB) levels (3, 6, and 12 months after surgery), early onset of cholangitis, and two-year native liver survival were evaluated. …”
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Osteosarcopenic Visceral Obesity and Osteosarcopenic Subcutaneous Obesity, Two New Phenotypes of Sarcopenia: Prevalence, Metabolic Profile, and Risk Factors by Simone Perna, Daniele Spadaccini, Mara Nichetti, Ilaria Avanzato, Milena Anna Faliva, Mariangela Rondanelli

“…OSVAT (versus the others) showed a higher level of inflammation (CRP and ESR, p<0.05), bilirubin (p<0.05), and risk of fractures (FRAX index over 15%, p<0.001). …”
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The Role of Gum Arabic for a Protective Kidney Dysfunction Induced Gentamicin on Diabetes Rats by Garsa Ali Alshehry

“…The kidney functions indicated to creatinine, urea, uric acid, blood urea nitrogen, and bilirubin were decreased from 1.34, 0.95, 2.24, 45.61, and 0.66 mg/dl in group (1) to 0.78, 29.84, 2.12, 16.25, and 018 mg/dL in group (4), respectively, when taking Gum Arabic. …”
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Clinical features of pneumatosis intestinalis induced by alpha- glucosidase inhibitor in patients with type 2 diabetes mellitus: a single center retrospective study by Guanlin Wu, Weiheng He, Huimin Rao, Lin Lu, Xinran He, Xuewen Hou

“…Additionally, the prevalence of coronary heart disease and hypertension was markedly higher in patients taking acarbose. Importantly, total bilirubin levels were lower in those with PI who were on acarbose therapy.ConclusionOur findings highlight the need for increased vigilance regarding the potential development of PI in older diabetic patients with cardiovascular conditions following αGI administration. …”
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Prediction and Risk Factors for Prognosis of Cirrhotic Patients with Hepatic Encephalopathy by Ying Peng, Qinglin Wei, Yun Liu, Zhenyu Wu, Hongjia Zhang, Hongbo Wu, Jin Chai

“…In multivariate regression analyses, serum biomarkers neutrophil and total bilirubin (TBIL) were independently correlated with in-hospital death. …”
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The feasibility of using liver function indices and FibroScan in combination to predict the occurrence of anti-tuberculosis drug-induced liver injury in Patients with liver disease by Shaoqiang Wu, Qiaohua Yang, Huai Li, Yongzhong Li

“…Results: Patients who developed DILI showed significantly higher levels of ALT, AST, total bilirubin, GGT, and LSM, with strong positive correlations between these markers and DILI occurrence. …”
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