Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Liver Failure Undergoing Plasma Exchange: A Single-Center Retrospective Study by Di Jin, Kai Kang, Bing-zhu Yan, Jian-nan Zhang, Jun-bo Zheng, Zhi-hui Wang, Di Wu, Yu-jia Tang, Xin-tong Wang, Qi-qi Lai, Yang Cao, Hong-liang Wang, Yang Gao

“…Baseline and clinical data were collected and calculated on admission to ICU before PE, including gender, age, height, weight, body mass index (BMI), etiology, total bilirubin, direct bilirubin, indirect bilirubin, prothrombin activity, model for end-stage liver disease (MELD) score, and sequential organ failure assessment (SOFA) score. …”
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Recipient Hyperbilirubinemia May Reduce Ischemia-Reperfusion Injury but Fails to Improve Outcome in Clinical Liver Transplantation by Mihai Oltean, Christian Barrenäs, Paulo Ney Martins, Gustaf Herlenius, Bengt Gustafsson, Styrbjörn Friman, William Bennet

“…Background. Exogenous bilirubin may reduce experimental ischemia-reperfusion injury (IRI) due to its antioxidant properties. …”
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Marked Direct Hyperbilirubinemia due to Ceftriaxone in an Adult with Sickle Cell Disease by Daniyeh Khurram, Leonid Shamban, Robert Kornas, Maryann Paul

“…It was predominantly conjugated bilirubin, with preadmission bilirubin levels of 3-4 mg/dL. …”
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Association between blood test indicators and atrial fibrillation in elderly patients aged 65 and above in the Central Jiangsu region: a cross-sectional study by Hao Liang, Shuai Zhang, Ye Zhu

“…Restricted cubic spline regression analysis showed a significant nonlinear relationship between direct bilirubin and AF (P for nonlinear < 0.001). The ROC curve analysis indicates that albumin, direct bilirubin, and uric acid all have good association strength with AF in elderly patients, with direct bilirubin showing the strongest association effect (AUC (95% CI) = 0.728 (0.686, 0.769)). …”
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Hyperbilirubinemia: Does It Matter? by Lajos Okolicsanyi, Giulia Martina Cavestro, Claudia Guatti-Zuliani

“…Serum bilirubin concentrations are increased in several hematological and hepatic disorders; however, hyperbilirubinemia, often of familial origin, may occur without overt signs of hemolysis or evident liver disease. …”
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Clinical characteristics of hereditary spherocytosis with red blood cell membrane protein gene variants by Jingying Cheng, Liqiang Zhang, Jiafeng Yao, Shasha Zhao, Jin Jiang

“…No statistical differences in hemoglobin levels, MCV, MCH, MCHC, or reticulocytes were observed across the various genetic variant groups. Bilirubin levels were remarkably elevated in patients with HS variants, and those with SPTB-HS had significantly higher bilirubin levels, including total bilirubin (p = 0.033) and indirect bilirubin (p = 0.018) compared to those with SPTA1-HS. …”
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Reproducibility of BiliCare™ Transcutaneus Bilirrubin Meter in Mexican Newborns by David Oldak, Gabriela García, Estela E. Gonzalez, Enver Aillon, Juan C. Falcon, Ernesto Ayala, Bernardo Oldak

“…BiliCare™ transcutaneous bilirubin measurement instrument has very good intra- and interdevice reproducibility; also correlation of TcS with serum bilirubin gave statistically the same results.…”
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Potential of albumin dialysis at terminal liver failure in patients with chronic liver diseases by O. E. Nikiforova, Ye. N. Bessonova, O. M. Lesnyak, O. A. Stroganova

“…Study results (triple decrease of bilirubin level and significant decrease of creatinine&gt; &lt;0,01). …”
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Spectrophotometric and enzymatic methods for biochemical analysis of blood sera from farm animals by D. S. Bolshakov, T. B. Nikeshina

“…Conventional and present-day principles of spectrophotometric and enzymatic determination of major biochemical values of animal blood serum (plasma) are described in the paper: total protein, albumin, urea, uric acid, creatinine, bilirubin (total and conjugated bilirubin), glucose, lactic acid, triglycerides, Cholesterine, phospholipids, calcium, magnesium, phosphorus, potassium, sodium, ferrum, chlorides, alkaline phosphatase, lactate dehydrogenase, creatine kinase, a-amylase, aspartate aminotransferase, alanine aminotransferase, Cholinesterase, γ-glutamyltransferase and hemoglobin.…”
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Neonatal and Maternal Risk Factors for Indirect Hyperbilirubinemia: A Cross-Sectional Study from Bahrain by Hasan M. Isa, Noor Y. AlBuainain, Fatema Y. Bunajem, Abdulrahman S. Masood, Yusuf A. Bucheery

“…The median indirect bilirubin level at presentation was 218 (interquartile range, 174-270) μmol/L. …”
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Computer-Aid System for Automated Jaundice Detection by Ahmad Yaseen Abdulrazzak, Saleem Latif Mohammed, Ali Al-Naji, Javaan Chahl

“…Severe cases of jaundice may cause acute bilirubin encephalopathy due to the toxicity of bilirubin to the cells of the brain, which may lead to kernicterus. …”
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Efficacy and Safety Concerns with Sn-Mesoporphyrin as an Adjunct Therapy in Neonatal Hyperbilirubinemia: A Literature Review by Prakar Poudel, Sudhir Adhikari

“…The rationale logic of heme oxygenase enzyme inhibition to lower bilirubin levels is intriguing. In compliance with that rationale, metalloporphyrin was discovered. …”
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Prognostic factors for survival in patients with advanced cholangiocarcinoma treated with percutaneous transhepatic drainage by Tomas Rohan, Barbora Cechova, Peter Matkulcik, Matej Straka, Jan Zavadil, Michal Eid, Michal Uher, Marek Dostal, Tomas Andrasina

“…A multivariate analysis showed that mass forming tumor with mass larger than 5 cm and presence of metastasis at the time of PTBD served as a negative prognostic factor (p = 0.002), better survival was associated with lower preprocedural bilirubin and lower CRP (p = 0.003). Multivariate analysis identified two significant risk factors for 3-month mortality: mass-forming tumors and bilirubin levels exceeding 185 µmol/L. …”
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Status survey of uncrossmatched type O suspended RBCs in patients with emergency transfusion by PENG Zhuoyue, XU Shilan, YANG Xinxin, CHEN Chunxia, TAN Bin

“…There was no significant difference in total bilirubin (TBIL), indirect bilirubin (IBIL) and lactate dehydrogenase (LDH) before and after blood transfusion (P>0.05). …”
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Bilothorax: A Case Report and Systematic Literature Review of the Rare Entity by Roshan Acharya, Smita Kafle, Yub Raj Sedhai, Dhan Bahadur Shrestha, Kevin Walsh, Wasif Elahi Shamsi, Suraj Gyawali, Nikita Acharya, Anthony Lukas Loschner, Edmundo Raul Rubio

“…The mean pleural fluid and serum bilirubin levels were 72 mg/dL and 61 mg/dL, respectively, with a mean pleural fluid-to-serum bilirubin ratio of 3.47. …”
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A 19-year-old Patient with Recurrent Pruritus and Jaundice by K. S. Nezhdanov, E. N. Shirokova, Yu. O. Shulpekova, A. S. Ostrovskaya, M. S. Zharkova, V. T. Ivashkin

“…Blood chemistry results revealed an elevation of total bilirubin (up to 634 μmol/L), direct bilirubin (up to 354 μmol/L), bile acids (up to 510 μmol/L) and normal gamma glutamyl transferase level. …”
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The molecular prevalence of Theileria equi in the Arabian stallion in Egypt with special reference to biochemical parameters by Noora F. Thabet, Omaima M. Kandil, Omnia M. Kandil, Khalid M. Fararh

“…Serum analysis revealed significant changes in the infected group's liver and kidney function parameters. Total bilirubin, direct bilirubin, indirect bilirubin, GGT, GOT (AST), urea, and creatinine were significantly increased in the serum of the infected group compared with the healthy group; total protein, albumin, and globulin were found to be decreased in the serum of the infected group when compared to the healthy group. …”
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Bile cast nephropathy (cholemic nephropathy) associated with hepatitis A-induced acute liver failure and haemolysis in a patient with glucose-6-phosphate dehydrogenase deficiency by Ali Hamdan, Johny Salem, Karam Karam, Maria Ziadeh, Pierre Hani

“…Laboratory results showed severe haemolysis and elevated bilirubin (70 µmol/l); hepatitis A serology was positive. …”
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Iodine-131 Combined With Plasma Exchange Treatment in Graves’ Hyperthyroidism Patients With Severe Liver Injury Whose Average Model for End-Stage Liver Disease Scores >20 by Xin-Fang Zhu, Rong-Rong Ding, Bing-Yao Wang, Yun-hui Yang, Fu-Xia Ta, Yuan Wang, Qing-Mei Gao, Qi Zhang, Rong Xia, Xing-Guang Luo, Xuan Wang, Jian-Ming Zheng, Hui-Qing Zhu

“…The level of total bilirubin at 3 months post-131I treatment was significantly lower than pre-131I treatment (P = .0200), the same was the level of direct bilirubin (P = .0200). …”
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Early Hepatic Dysfunction in a Large Animal Model of Nonhypotensive Sepsis by Stephen Sullivan, Michael Troster, Adam Linton

“…By 24 h there was a significant drop in albumin and alkaline phosphatase with increases in aspartate aminotransferase (AST), lactate dehydrogenase and bilirubin. By 48 h the alkaline phosphatase had returned to presepsis levels, the bilirubin continued to rise, the AST and lactate dehydrogenase had plateaued while the alhumin remained low. …”
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