Advance in identified targets of berberine by Penghai Sun, Ziyuan Wang, Yinchao Ma, Yuan Liu, Yintong Xue, Yan Li, Xiang Gao, Yuedan Wang, Ming Chu, Ming Chu, Ming Chu, Ming Chu

Subjects: “…berberine…”
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Berberine-induced browning and energy metabolism: mechanisms and implications by Aslıhan Alpaslan Ağaçdiken, Zeynep Göktaş

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Development of Bioadhesive Microspheres for Oral Bioavailability Enhancement of Berberine Hydrochloride by Ye Zhang, Hongming Liu

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Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model by Yaoyi Zhang, Shuai Lv, Pinyuan Huang, Lingmin Xiao, Nan Lin, En Huang

“…Abstract Research indicated that berberine (BBR) plays a protective role in modulating Alzheimer’s disease (AD). …”
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Interaction of Herbal Compounds with Biological Targets: A Case Study with Berberine by Xiao-Wu Chen, Yuan Ming Di, Jian Zhang, Zhi-Wei Zhou, Chun Guang Li, Shu-Feng Zhou

“…Berberine is one of the main alkaloids found in the Chinese herb Huang lian (Rhizoma Coptidis), which has been reported to have multiple pharmacological activities. …”
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Neuroprotective Effects of Metformin and Berberine in Lipopolysaccharide-Induced Sickness-Like Behaviour in Mice by Triveni Kodi, Sharanya Praveen, Sravan Kumar Paka, Runali Sankhe, Adarsh Gopinathan, Nandakumar Krishnadas, Anoop Kishore

“…Similarly, the reported anti-inflammatory activities of berberine could be partially attributed to its ability to activate AMPK. …”
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Molecular Basis of Inhibitory Activities of Berberine against Pathogenic Enzymes in Alzheimer's Disease by Hong-Fang Ji, Liang Shen

“…The natural isoquinoline alkaloid berberine possesses potential to treat Alzheimer's disease (AD) by targeting multiple pathogenic factors. …”
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Studies on the Dual Cytotoxicity and Antioxidant Properties of Berberis vulgaris Extracts and Its Main Constituent Berberine by Lamyae El khalki, Mounir Tilaoui, Abdeslam Jaafari, Hassan Ait Mouse, Abdelmajid Zyad

“…The present study attempts to investigate the cytotoxic activity of ethanol and ethyl acetate extracts of the Moroccan Berberis vulgaris and its major component berberine, together with exploring their antioxidant properties. …”
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Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways by Li Jia, Kuijin Xue, Junheng Liu, Ola A. Habotta, Lianhai Hu, Ahmed E. Abdel Moneim

“…Berberine (BER), a natural isoquinoline alkaloid, has been demonstrated to have appreciable anticolitis effects. …”
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The potential therapeutic role of berberine in treating epilepsy focusing on temporal lobe epilepsy: State of art and ongoing perspective by Bshra A. Alsfouk, Hayder M. Al-Kuraishy, Ali K. Albuhadily, Ali I. Al-Gareeb, Ahmed M. Abdelaziz, Athanasios Alexiou, Marios Papadakis, Mubarak Alruwaili, Gaber El-Saber Batiha

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Berberine decorated zinc oxide loaded chitosan nanoparticles a potent anti cancer agent against breast cancer by Fatemeh Esnaashari, Hojjatolah Zamani, Hossein Zahmatkesh, Mojtaba Soleimani, Golnesa Amirian Dashtaki, Behnam Rasti

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Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4 by Ming Zhang, Chun-Mei Wang, Jing Li, Zhao-Jie Meng, Sheng-Nan Wei, Ji Li, Richard Bucala, Yu-Lin Li, Li Chen

“…Endothelial dysfunction is a critical factor during the initiation of cardiovascular complications in diabetes. Berberine can ameliorate endothelial dysfunction induced by diabetes. …”
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Evaluation of the Antioxidant Properties and Biological Effects of a Novel Combined Barberry Root–Propolis Extract on HEK293T Cells by Dana Marcinčáková, Nikola Hudáková, Michal Miłek, Mária Kolesárová, Małgorzata Dżugan, Dasa Cizkova, Jaroslav Legáth

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Advances in the biosynthesis of naturally occurring benzylisoquinoline alkaloids by Wanli Zhao, Jihua Liu, Yu Chen

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Biomarker discovery and phytochemical interventions in Alzheimer's disease: A path to therapeutic advances by Mithila Debnath, Mahir Azmal, Rashid Taqui, Moshiul Alam Mishu, Ajit Ghosh

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Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus by Maheswata Sahoo, Lingaraja Jena, Sangeeta Daf, Satish Kumar

“…Amongst these four drugs, berberine has shown highest binding affinity of –5.8 kcal/mol and it is binding around the active site region of the receptor. …”
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Molecular and cellular aspects of the impact of secondary metabolites from common barberry and hybrid goat’s rue on the HeLa cell line by E. Yu. Zlatnik, Ya. S. Enin, O. N. Burov, E. S. Bondarenko, A. B. Sagakyants, D. S. Kutilin, Yu. V. Dzigunova, O. G. Ishonina, E. V. Shalashnaya, N. D. Ushakova

“…All compounds used in the experiment exhibited a cytotoxic effect on the HeLa cell line. Berberine alkaloid showed the most pronounced cytotoxic effect on the HeLa line as recorded by all methods used in the study. …”
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Effect of magnetization on antibacterial, lipid-lowering and antioxidant activities of isoquinoline alkaloids by Xueting Feng, Weijie Li, Xiaoling Wang, Jie Tang, Shun Yao

“…Therefore, the antibacterial, lipid-lowering and antioxidant activities of five isoquinoline alkaloids (berberine, tetrahydroberberine, palmatine, tetrahydropalmatine and tetrahydropapavine) before and after magnetization were compared in this study, and the results showed that the relevant activities were enhanced after magnetization. …”
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Poly(lactic-co-glycolic acid) Nanoparticles Loaded with Callistemon citrinus Phenolics Exhibited Anticancer Properties against Three Breast Cancer Cell Lines by Rashid Ahmed, Muhammad Tariq, Irfan S. Ahmad, Hanafy Fouly, Fakhar-i-Abbas, Anwarul Hasan, Mosbah Kushad

“…Nanoencapsulated phenolics from C. citrinus extract, berberine, and combination of both enhanced their bioactivity against the three breast cancer cell lines by nearly 2-fold. …”
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A new strategy for pharmacodynamic substance screening and research on gut microbiota pathway mechanisms based on UPLC-Q-orbitrap-MS and 16S rRNA by Zhiying Yu, Tong Li, Jie Yang, Jianghua He, Weijiang Zhang, Siyuan Li, Yunpeng Qi, Yihui Yin, Ling Dong, Wenjuan Xu

“…The primary prototype components are flavonoids and alkaloids, including puerarin (PUE), baicalin (BAI), and berberine (BER). The metabolism was predominantly sulfonation. …”
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