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18821
The long-term impact of childhood sexual assault on depression and self-reported mental and physical health
Published 2025-01-01“…This study quantifies the impact of CSA on the likelihood of being diagnosed with depression in adulthood, as well as its influence on poor mental and physical health days.MethodsWe analyzed data from the Behavioral Risk Factor Surveillance System (BRFSS) (2016–2023), comprising 321,106 respondents. …”
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18822
On the Subject, Purpose and Method of Religious Education as a Practical Metaphysics
Published 2024-10-01“…And pedagogy, on the other hand, depends on the paradigm of existence, human being and behavior that finds its meaning in natural sciences such as physics and biology, human sciences, especially psychology, and educational sciences, which have been established depending on the natural state in which modernity is formed. …”
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18823
Management of mangrove landscape and ecosystem for ecotourism
Published 2024-10-01“…Through thorough study and analysis of both human behavior and natural processes, effective management strategies can be developed to support ecotourism initiatives. …”
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18824
Mental health phenotypes of well-controlled HIV in Uganda
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18825
Function mechanism of turbulent eddy and process intensification of particle-bubble collision in fine mineral flotation
Published 2024-12-01“…In this study, the microscale dynamic behavior of fluids, particles, and bubbles in an isotropic turbulent field was measured using high-frequency particle image velocimetry and high-speed microscopic camera technology. …”
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18826
Associations between Prospective Memory, Executive Function and Physical Activity in Schoolchildren
Published 2025-01-01“…Executive function such as working memory or inhibition are responsible for goal-directed behavior and cognitive control processes. Those cognitive abilities are critical for successfully coping with everyday challenges from school age to late adulthood (Diamond, 2013). …”
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18827
Design and Validation of Policy Making Model with Open Government Approach
Published 2024-06-01“…These include structural factors such as information technology integration, policy-making processes, technical and operational support, financial and budget considerations, and organizational structure. Behavioral factors encompass leadership and management styles, human resources management, educational initiatives, and organizational justice practices. …”
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18828
Early Prediction of Abdominal Aortic Aneurysm Rupture Risk Using Numerical Biomechanical Analysis
Published 2024-12-01“…<b>Objective</b>: We aimed to predict patient-specific rupture risks and growth behaviors in abdominal aortic aneurysm (AAA) patients using biomechanical evaluation with finite element analysis to establish an additional AAA repair threshold besides diameter and sex. …”
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18829
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18830
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18831
Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia
Published 2025-01-01“…This study aims to explore the depression-like behavior, sleep changes, central oxidative stress response, pineal mitochondrial autophagy damage, melatonin secretion, histopathological changes of the pineal gland, and the expression of Pink1/Parkin signaling-related factors in CUMS+SD rats. …”
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18832
Ameliorating potential effects of natural biological formulations and biostimulants on plant health and quality attributes in coriander-fenugreek intercropped strawberry (Fragaria...
Published 2025-02-01“…This study inferred that application of bio-organic inputs sources which can boost up cropping behavior, post harvest soil indicators, native microbial properties and enzymatic activity in rhizosphere, and thus can have the potential to improve crop resilience and soil productivity on sustainable basis.…”
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18833
Enhancing surveillance for dengue fever in Oyo State, Nigeria – a one health approach
Published 2025-01-01“…In Oyo State, Nigeria, the true burden of DF remains unknown due to underdiagnosis and misdiagnosis as malaria, exacerbated by poor health-seeking behavior, weak surveillance systems, and inadequate health infrastructure. …”
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18834
Protein kinase inhibitors as targeted therapy for glioblastoma: a meta-analysis of randomized controlled clinical trials
Published 2025-02-01“…Upon disease progression, the anti-vascular endothelial growth factor-A (VEGF-A) monoclonal antibody bevacizumab, can be considered.Given the limited efficacy of pharmacological treatments, particularly for the recurrent disease, several molecularly targeted interventions have been explored, such as small-molecule protein kinase inhibitors (PKIs), inhibiting tyrosine kinase growth factor receptors and downstream signaling pathways involved in GBM angiogenesis and infiltrative behavior.This meta-analysis, based on searches in PubMed and Web Of Science, evaluated 12 randomized controlled trials (RCTs) examining PKIs in patients with newly diagnosed or recurrent GBM. …”
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18835
The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity
Published 2025-01-01“…Importantly, tPA deficiency protects DA-neurons from degeneration, prevents behavioral deficits, and reduces microglia activation and T-cell infiltration induced by α-synuclein overexpression. …”
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18836
Effects of non-pharmacological interventions on the depressive outcomes in people with mild cognitive impairment: an overview of systematic reviews
Published 2025-01-01“…Three SRs focused on cognitive interventions (general, computer-based, cognitive stimulation/rehabilitation), six reviews on physical activity (Tai Chi, exercise therapy, dance), three on psychosocial interventions including cognitive behavioral therapy (CBT), mindfulness-based intervention (MBI) and type not specified, one on music therapy, and one on health education; moreover, there were two SRs on multimodal NPIs. …”
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18837
MicroRNA-132, Delivered by Mesenchymal Stem Cell-Derived Exosomes, Promote Angiogenesis in Myocardial Infarction
Published 2018-01-01“…Considering that microRNA-132 (miR-132) regulates endothelial cell behavior during angiogenesis and the safe and efficacious delivery of microRNAs in vivo is rarely achieved, an ideal vehicle for miR-132 delivery could bring the promise for ischemic diseases. …”
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18838
PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way
Published 2022-10-01“…The dynamics of the in vivo behaviors of NDCs were assessed based on multiorgan changes in PD-L1 levels.Results The screened PD-L1 nanobodies were characterized as tumor-targeting and alleviated T-cell immunosuppression. …”
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18839
Role of BDNF-TrkB signaling in the improvement of motor function and neuroplasticity after ischemic stroke in rats by transcranial direct current stimulation
Published 2025-01-01“…Methods: A middle cerebral artery occlusion-reperfusion(MCAO/R) model was established in rats to observe tDCS effects on brain damage. Behavioral tests, the modified neurologic severity score(mNSS), and the Hoffman reflex / the M wave(Hmax/Mmax) ratio helped assess motor function and neurologic deficits. …”
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18840
Enhanced fibrotic potential of COL1A1hiNR4A1low fibroblasts in ischemic heart revealed by transcriptional dynamics heterogeneity analysis at both bulk and single-cell levels
Published 2025-01-01“…BackgroundFibroblasts in the fibrotic heart exhibit a heterogeneous biological behavior. The specific subsets of fibroblasts that contribute to progressive cardiac fibrosis remain unrevealed. …”
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