Rab21-Targeted Nano Drug Delivery System-Based FFPG for Efficient Paclitaxel Delivery to Inhibit Lung Cancer Progression by Jing Wang, Xueying Yan, Wenfei Wang, Shu Wang, Hongxiang Jiang, Xinhua Zhu, Zhehui Li, Defu Cai, Yonggang Xia

“…Dynamic light scattering, zeta potential, and transmission electron microscopy were used for physical characterization. The release behavior of the NDDS was simulated by dialysis. The uptake of the NDDS was observed by confocal microscopy and flow cytometry. …”
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Can serum orexin levels be used as a marker in childhood epilepsy? by Mutluay Arslan, Canan Üstün, Ayşe Nur Coşkun, Hasan Çelik, Hacı Nadir Yalçın, Eda Karaismailoğlu, Erdim Sertoğlu, Bülent Ünay

“…Orexins are excitatory peptides and associated with energy homeostasis, eating and drinking behaviors, sleep regulation, sleep-wake periods, analgesia, and cognitive activities such as attention, learning, and memory. …”
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Heat transportation of 3D chemically reactive flow of Jeffrey nanofluid over a porous frame with variable thermal conductivity by Nahid Fatima, Aaqib Majeed, Taoufik Saidani, Nouman Ijaz, Kamal Barghout, Nidal Abu-Libdeh

“…This research advances the understanding of non-Newtonian thermally radiative flow with variable thermal conductivity, elucidating the complex behavior of such fluids and providing valuable insights for engineering applications.…”
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Protocol for a nested case-control study: identifying neuroimaging biomarkers for the progression of subclinical depression and qi-stagnation constitution to major depressive disor... by Jing Wang, Chengfeng Zhang, Yueqi Zhang, Yuanyuan Liu, Jingli Zhang, Xingwei Fang, Wangyang Xia, Yanzhao Xie, Zhongli Lan, Jinhui Wang, Jinhui Wang, Jinhui Wang, Jinhui Wang, Min Lu, Jun Chen, Jun Chen

“…BackgroundMajor depressive disorder (MDD) frequently results in suboptimal treatment outcomes and elevated recurrence rate, with patients frequently engaging in self-harm and suicidal behavior, thereby placing a heavy burden on families and society. …”
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Water security in North Carolina’s most economically insecure county: a case study by Hana C Long, Beverly Collins-Hall, Kaelan Moore, Bethany Cutts, Jacqueline MacDonald Gibson

“…Semi-structured interviews conducted with community members were analyzed to identify concerns about drinking water security (including safety, affordability, and reliability), perceptions of water quality, averting behaviors taken due to water insecurity, and ideas for improving water security. …”
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Application of artificial intelligence brain structure-based paradigm to predict the slip condition impact on magnetized thermal Casson viscoplastic fluid model under combined temp... by Umar Farooq, Shan Ali Khan, Haihu Liu, Muhammad Imran, Lotfi Ben Said, Aleena Ramzan, Taseer Muhammad

“…In this article, computational ANN paradigms are utilized in the analysis of boundary layer flow and heat transfer of magnetized Casson fluid over a nonlinearly stretching elastic sheet under velocity slip conditions. Casson fluid behavior under the influence of magnetohydrodynamics with the influence of heat generation, temperature-dependent dynamic viscosity, variable thermal conductivity, and viscous dissipation are considered in this study. …”
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Japi 2.0, a gaming platform to stimulate cognitive and non-cognitive skills in early childhood: protocol for a pilot randomized controlled trial by Jorge Gaete, Saray Ramírez, Cristian A. Rojas-Barahona, Valentina Romo, Natalia Ríos, Ricardo Araya

“…This platform stimulates cognitive and non-cognitive skills with the final objective of reducing emotional and behavioral problems in early childhood. Evaluating the acceptability and feasibility of this technological solution for children is expected to produce relevant information about these novel designs. …”
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Detection and Classification of Teacher-Rated Children’s Activity Levels Using Millimeter-Wave Radar and Machine Learning: A Pilot Study in a Real Primary School Environment by Tianyi Wang, Takuya Sakamoto, Yu Oshima, Itsuki Iwata, Masaya Kato, Haruto Kobayashi, Manabu Wakuta, Masako Myowa, Tokomo Nishimura, Atsushi Senju

“…Traditional assessments of children’s health and behavioral issues primarily rely on subjective evaluation by adult raters, which imposes major costs in time and human resource to the school system. …”
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Composite Flours Based on Black Lentil Seeds and Sprouts with Nutritional, Phytochemical and Rheological Impact on Bakery/Pastry Products by Christine (Neagu) Dragomir, Sylvestre Dossa, Călin Jianu, Ileana Cocan, Isidora Radulov, Adina Berbecea, Florina Radu, Ersilia Alexa

“…For use in baking/pastries, the composite flours were tested from the point of view of rheological behavior using the MIXOLAB system, and the profiles obtained were compared with those of bread and biscuit. …”
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Health Risk Assessment of Chemicals: From Bulk to Nano by Soqrat Omari Shekaftik, Jamal Biganeh, Maedeh Hosseinzadeh, Hamidreza Jafari Nodoushan, Neda Mehrparvar

“…The preference for qualitative over quantitative methods in the risk assessment of activities involving nanomaterials stems from substantial uncertainties, limited data availability, and the unique and complex behaviors of nanomaterials in the workplaces. Conclusion: Overall, the evolution of health risk assessment methods reflects a continuous drive towards greater accuracy, reliability, and relevance. …”
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Dynamic rationing using agent-based modeling of the assembly process of equipment for nuclear power plants by I. A. Loskutov, D. A. Skvortsova, V. G. Iskandarova

“…The components of programs implemented in the C# language are shown, descriptions of classes are described, their actions to simulate the behavior of agents of a production system. The class diagram shows the selected classes and the relationships between them in terms of inheritance. …”
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Comparative profitability of agroecological practices in Ethiopian wheat farming by Stanley Karanja Ng’ang’a, Sylvester Ochieng Ogutu, Degefie Tibebe, Devinia Akinyi, Jonathan Mockshell

“…Other factors, including social and behavioral aspects, influence farmer decisions. Future research should integrate these dimensions to develop comprehensive strategies for promoting agroecological practices.ConclusionAdopting agroecological practices has clear economic benefits for Ethiopian wheat farmers, with certified seeds emerging as the most profitable option. …”
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Prognostic implications of immune classification based on PD-L1 expression and tumor-infiltrating lymphocytes in endocervical adenocarcinoma by Li-Jun Wei, Zi-Yun Wu, Li-Yan Wu, Ying-Wen Wu, Hao-Yu Liang, Rong-Zhen Luo, Li-Li Liu

“…Given the variability in pathological features and clinical behavior between the subtypes, evaluating their respective immune microenvironments is essential. …”
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Knowledge, Awareness, and Influence of the COVID-19 Pandemic on Students of Biomedical Faculties: A Cross-Sectional Study by Bruno Špiljak, Luka Šimunović, Ana Marija Miličević, Marko Granić, Lana Bergman, Jasminka Peršec

“…This study aimed to explore and compare differences in knowledge, awareness, behavior, and the psychological impact of the pandemic among students of biomedical faculties at the University of Zagreb. …”
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Exploring mental health in veterinary students: common stressors and effective coping strategies: a narrative review by Rahib K. Islam, Emily K. Cobb, Hannah K. McCowan, Kylie Watson, Kaustuv Bhattacharya, Kaustuv Bhattacharya, Anjali Chandra, Warda Mohiuddin, Karen Gruszynski, Karen Gruszynski, Amanda H. Wilkerson, John J. Dascanio, Robert E. Davis, Vinayak K. Nahar, Vinayak K. Nahar

“…Effective coping strategies included exercise and social activities; whereas, harmful behaviors like substance misuse exacerbated mental health issues. …”
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Microstructural modifications in bitumens rejuvenated by oil from pyrolysis of waste tires by Michela Alfe, Valentina Gargiulo, Giovanna Ruoppolo, Francesco Cammarota, Pietro Calandra, Cesare Oliviero Rossi, Valeria Loise, Michele Porto, Roberto Di Capua, Paolino Caputo

“…Bitumen was aged by the rolling thin-film oven test procedure and blended with the WT pyrolysis oil at three different concentrations (1%, 3%, and 6% w/w) to evaluate the rheological behaviors. The blends were also investigated using atomic force microscopy, and the asphaltenic fraction was assessed via optical microscopy.Results and discussionAll the data consistently indicate that oil addition not only reduces the viscosity of bitumen and restores it to values close to the original unaged bitumen but also changes the intermolecular structure to recover the self-assembly pattern typical of the unaged sample. …”
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Assessment of heavy metal contamination in surface sediments: Seasonal influence in the Majes-Camaná basin of the Arequipa region, Peru by María Claudia Cáceres Obada, María Eduarda Fernanda Zegarra Oliveira, Naysha Yamelit Meza Elguera, Stephanie Elena Sosa Pulcha, Abdel Alejandro Portocarrero Banda, Jhon Alfredo Quispe Ortiz, Verónica Salinas Murillo, Hugo Guillermo Jiménez Pacheco

“…Additionally, the general behavior for both periods follow the order: Zn > Cu > Cr > Ni > As > Pb > Cd. …”
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Toxic Assessment of Heavily Traffic-related Fine Particulate Matter Using an in-vivo Wild-type Caenorhabditis elegans Model by Meng-Ching Chung, Kuo-Lin Huang, Japheth L. Avelino, Lemmuel L. Tayo, Chih-Chung Lin, Ming-Hsien Tsai, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang

“…In the present study, the toxicity of traffic-related-air-pollutant (TRAP) PM2.5 was evaluated in the animal model Caenorhabditis elegans (C. elegans) using different toxicological endpoints such as lethality, survivability (lifespan), behavioral (head thrashing and body bending), and reproduction (brood size). …”
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Investigating dynamic brain functional redundancy as a mechanism of cognitive reserve by Julia Schwarz, Franziska Zistler, Adriana Usheva, Anika Fix, Sebastian Zinn, Juliana Zimmermann, Franziska Knolle, Franziska Knolle, Gerhard Schneider, Rachel Nuttall

“…In this study we aimed to investigate whether BFR modulates the association between age-related brain changes and cognitive performance across a broad range of cognitive domains.MethodsAn open-access neuroimaging and behavioral dataset (n = 301 healthy participants, 18–89 years) was analyzed. …”
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An online intervention relationship enhancement couple therapy program versus systematic desensitization on sexual performance anxiety in women undergoing infertility treatment wit... by Maryam Afzal Dehkordi, Tahmineh Farajkhoda, Mahdi Khanabadi, Farimah Shamsi

“…RECT (couple relationship-centered) by empowering 10 interpersonal skills, and SD (personal-oriented) by learning step-by-step how fight-or-flight response is replaced by relaxation response, helping women perform more adaptive behaviors regarding sexual anxiety. RECT increased spouse satisfaction significantly compared to SD, indicating that males need to participate in positive relationship changes. …”
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