Case report: Long-term efficacy and safety of semaglutide in the treatment of syndromic obesity in Prader Willi syndrome - case series and literature review by Andrijana Koceva, Andrijana Koceva, Katarina Mlekuš Kozamernik, Katarina Mlekuš Kozamernik, Andrej Janež, Andrej Janež, Rok Herman, Rok Herman, Simona Ferjan, Simona Ferjan, Mojca Jensterle, Mojca Jensterle

“…As hyperphagia, satiety dysfunction and consequent food-seeking behaviors are intrinsic to PWS, obesity management can be challenging.Case seriesWe present a long-term follow-up of treatment with GLP-1 receptor agonist (GLP-1 RA) semaglutide in three patients with PWS without diabetes, one of whom had previously undergone metabolic surgery. …”
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A Novel Nitronyl Nitroxide with Salicylic Acid Framework Attenuates Pain Hypersensitivity and Ectopic Neuronal Discharges in Radicular Low Back Pain by Wen-Juan Han, Lei Chen, Hai-Bo Wang, Xiang-Zeng Liu, San-Jue Hu, Xiao-Li Sun, Ceng Luo

“…Furthermore, SANR-induced behavioral analgesia is found to be mediated, at least in partial, by a reduction of ectopic spontaneous discharges in injured DRG neurons. …”
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A Case of Rafiq Syndrome (MAN1B1-CDG) in a Palestinian Child, With Brief Literature Review of 44 Cases by Reema Iskafi MD, Bahaa AbuRahmeh MD, Roa’a Aljuneidi MD, Hidaya AlShweiki MD, Siraj Abdelnabi MD, Anas Abukhalaf MBBS, Bara’ Maraqa PBoS

“…In this study, we discuss a 5-year-old male from Palestine who presented with developmental delay, hypotonia, characteristic facial dysmorphisms, impulsive behaviors, inability to speak, cryptorchidism, and other manifestations. …”
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Variation in energetic balance among free-ranging polar bears during the spring mating and foraging season by Anthony M. Pagano, Stephen N. Atkinson, Louise C. Archer

“…The marked variation in mass gains or losses highlights the varying behavioral and physiological limitations that influence foraging success within this apex carnivore during a season when two key life history events converge wherein feeding is often reduced during mating activities despite the importance of the spring hyperphagia period to long-term energy balance.…”
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Electric Vehicles Charging Scheduling Strategy Based on Time Cost of Users and Spatial Load Balancing in Multiple Microgrids by Jiaqi Zhang, Yongxiang Xia, Zhongyi Cheng, Xi Chen

“…Uncontrolled charging behaviors of large-scale EV fleets will exacerbate loads imbalanced in a multi-microgrid (MMG). …”
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OHMi Estarreja: an ecosystem highly anthropized where contamination is the unifying element towards interdisciplinarity by Bedell, Jean-Philippe, Guihard-Costa, Anne-Marie, Paiva, Cristiana, Machado, Diogo, Cachada, Anabela, Patinha, Carla, Durães, Nuno, Sousa, Ana Catarina, Beurier, Anne-Gaëlle, Ferreira da Silva, Eduardo

“…Another OHMi Estarreja originality is that human health projects are being carried out at the local level, under a double geochemical and socio-behavioral approach. Lastly, the Estarreja region is also part of one of the most important wetland ecosystems from Portugal, the Baixo Vouga Lagunar. …”
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Analyzing Geospatial and Socioeconomic Disparities in Breast Cancer Screening Among Populations in the United States: Machine Learning Approach by Soheil Hashtarkhani, Yiwang Zhou, Fekede Asefa Kumsa, Shelley White-Means, David L Schwartz, Arash Shaban-Nejad

“…MethodsData on mammography screening at the census tract level for 2018 and 2020 were collected from the Behavioral Risk Factor Surveillance System. We developed a large-scale dataset of social determinants of health, comprising 13 variables for 72,337 census tracts. …”
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Diet, Physical Activity, Weight Status, and Culture in a Sample of Children from the Developing World by Pamela S. Gaskin, Pamela Lai, Devon Guy, JaDon Knight, Maria Jackson, Anders L. Nielsen

“…We describe the food and activity preferences and adult encouragement of active and sedentary behaviors for children 9–11 years in relation to weight status and the cultural context. …”
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7,8-Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone-Induced Neurotoxicity in Rodents by Shuke Nie, Kai Ma, Mingkuan Sun, Matthew Lee, Yang Tan, Guiqin Chen, Zhentao Zhang, Zhaohui Zhang, Xuebing Cao

“…The results revealed that treatment with 7,8-DHF improved PD model’s behavioral performance and reduced dopaminergic neuron loss in the SN and striatum, associated with the activation of TrkB receptors and its signaling cascades, and reduced p-MAPK, p-α-synuclein, and p-tau. …”
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Situation Awareness-Based Safety Assessment Method for Human–Autonomy Interaction Process Considering Anchoring and Omission Biases by Shengkui Zeng, Qidong You, Jianbin Guo, Haiyang Che

“…In SAB-TDM, SA perception and comprehension affected by anchoring bias are quantified with the Adaptive Control of Thought-Rational (ACT-R) theory and Anchoring Adjustment Model (AAM); behavioral utility prediction affected by omission bias is quantified with Prospect Theory. …”
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Effects of Ficus umbellata (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats by Stéphane Zingue, Harquin Simplice Foyet, Sefirin Djiogue, Yannick Ezo’o Ezo’o, Hervé Hervé Ngatanko Abaïssou, Pafroumi Fachagbo, Dieudonné Njamen

“…Before and after the memory impairment with scopolamine (2 mg/kg BW), animals underwent behavioral evaluations on Y- and radial mazes. As results, age and ovariectomy did not induce significant changes in the reference memory errors. …”
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Experimental Study on the Effects of Stress-Induced Damage on the Microstructure and Mechanical Properties of Soft Rock by Hao Wang, Yong-Yan Wang, Zhuo-Qun Yu, Jian-Guang Li

“…Studying the microstructures and mechanical behaviors of stress-damaged rocks can help better guide construction and reduce construction risks for geotechnical engineering projects. …”
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Case study of a neuroendocrine tumor of uncertain origin: single-cell transcriptomics unravels potential primary location by Frolova Tatyana, Ekaterina Avsievich, Diana Salimgereeva, Zoia Antysheva, Alesia Maluchenko, Denis Maksimov, Ilia Feidorov, Mark Voloshin, Olga Glazova, Natalia Bodunova, Nikolay Karnaukhov, Pavel Volchkov, Julia Krupinova

“…Neuroendocrine tumors are rare neoplasms with diverse clinical behaviors. Determining their primary origin remains challenging in cases of non-organ-confined NETs. …”
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Clinical features and predictors of atrial fibrillation in patients with light‐chain or transthyretin cardiac amyloidosis by Maria Papathanasiou, Aiste‐Monika Jakstaite, Sara Oubari, Johannes Siebermair, Reza Wakili, Julia Hoffmann, Alexander Carpinteiro, Tim Hagenacker, Andreas Thimm, Christoph Rischpler, Lukas Kessler, Tienush Rassaf, Peter Luedike

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Determinants of the Continuum of Maternal Healthcare Services in Northwest Ethiopia: Findings from the Primary Health Care Project by Asmamaw Atnafu, Adane Kebede, Bisrat Misganaw, Destaw Fetene Teshome, Gashaw Andargie Biks, Getu Debalkie Demissie, Haileab Fekadu Wolde, Kassahun Alemu Gelaye, Mezgebu Yitayal, Tadesse Awoke Ayele, Telake Azale, Terefe Derso, Tsegaye Gebremedhin, Endalkachew Dellie

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Differentiating Between Perfluorohexyloctane Ophthalmic Solution and Water-Free Cyclosporine Ophthalmic Solution 0.1% for Dry Eye Disease: A Review of Preclinical and Clinical Char... by Laura M. Periman, Darrell E. White, Douglas Katsev

“…The structure of these SFAs determines their differing behaviors and functions. The longer chain length of PFHO results in a slower evaporation rate and facilitates formation of a stable monolayer on the ocular surface. …”
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Quelles balises curriculaires en éducation à la prospective territoriale durable ? Valeurs d’émancipation et finalités d’implications politiques des jeunes dans les études de cas e... by Angela Barthes, Sylviane Blanc-Maximin, Elisabeth Dorier

“…It is a question of promoting collective management of the public affairs of young people without introducing into individual behavioral normalisations. The curriculum guidelines are based on the epistemological framework of "educations for", that of critical thinking, and on an adaptation of the common base of knowledge of skills and culture (MEN, 2015). …”
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Financing the future: insights into sustainable energy investments through scientific mapping and meta-analysis by Mustafa Raza Rabbani, Madiha Kiran, Zakir Hossen Shaikh

“…The insights from this study aim to inspire and equip readers as they embark on their inquiries into the connections between energy investment, policy, finance, and behavioral sciences. Following identifying research gaps, this paper outlines potential future research directions. …”
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Causes and Intervention Strategies to Reduce Childhood Obesity in Ambato by Carlos David Castañeda Guillot, Diego Fernando Vaca Sánchez, María Augusta Reyes Pérez

“…<br /><strong>Results:</strong> obese patients predominated in an age range of 13 years or more and were female. 86 % of patients showed excessive consumption of sweets and snacks, spending more than 30 hours a week in front of digital devices, and 73.1 % showed inappropriate family behaviors. An educational program was proposed with 5 sessions that includes: objectives, content and specific evaluations. …”
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Cats and dogs cross the line: domestic breeds follow Rensch’s rule, their wild relatives do not by C. J. Bidau, P. A. MartÍnez

“…The domestication syndrome already recognized by Darwin shows that domesticated species acquire a number of novel morphological, physiological and behavioral characteristics not present in their wild ancestors. …”
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