The Impact of Transcriptomics on the Fight against Tuberculosis: Focus on Biomarkers, BCG Vaccination, and Immunotherapy by Carlos Rodrigo Zárate-Bladés, Celio Lopes Silva, Geraldo A. Passos

“…This paper analyzes how transcriptomics are supporting the translation of basic research into therapies by resolving three key issues in the fight against TB: (a) the discovery of biomarkers, (b) the explanation of the variability of protection conferred by BCG vaccination, and (c) the development of new immunotherapeutic strategies to treat TB.…”
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OUTSOURCING OF R&D AND INNOVATION ACTIVITIES IN SMEs: EVIDENCE FROM SLOVENIA by Barbara Bradač Hojnik, Miroslav Rebernik

“…When comparing the type of R&D and innovation activities that are outsourced, the results show that SMEs mainly outsource experimental development, followed by basic research and applied research. However, they mostly outsource R&D and innovation activities to universities and independent research organisations and only occasionally to private organisations from industry and individual researchers. …”
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Research Status of Clustered Regulary Interspaced Short Palindromic Repeats Technology in the Treatment of Human Papillomavirus (HPV) Infection Related Diseases by Minxue Tang MD

“…Research Design: This article provides an overview of the advancements made in utilizing the CRISPR-Cas9 system as a research tool for HPV-related treatments while summarizing its application status in basic research, diagnosis, and treatment of HPV. Data Collection: Furthermore, it discusses the future prospects for this technology within emerging areas of HPV research and precision medicine in clinical practice, while highlighting technical challenges and potential directions for future development.…”
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A Group Rotate-Vector Algorithm for Mixed-Variable Optimization Problems by Zhongming Li, Lutao Yan, Haiyuan Li, Lianxin Wang

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Myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment and their targeting in cancer therapy by Shuyan He, Lu Zheng, Chunjian Qi

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Microservice-Based Platform for Space Situational Awareness Data Analytics by Wanjie Lu, Qing Xu, Chaozhen Lan, Liang Lyu, Yang Zhou, Qunshan Shi, Yinghao Zhao

“…However, researchers cannot flexibly and conveniently apply the research results to practical applications due to the lack of basic research platforms for SSA. Inspired by X as a Service (XaaS), we propose the microservice-based platform for SSA data analytics to provide a scaffold-like platform for researchers. …”
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Development and regional characteristics of the Hungarian information and communication sector (ICT) by Gábor Nagy, Imre Kanalas

“…The rising ICT sector and new elements of information society implied a special interest not only from basic research, but even applied research areas, for example the emerging role of ICTs in regional development and regional policies and some sectoral policies (economy, education, health etc.). …”
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On the Usage of GPUs for Efficient Motion Estimation in Medical Image Sequences by Jeyarajan Thiyagalingam, Daniel Goodman, Julia A. Schnabel, Anne Trefethen, Vicente Grau

“…Images are ubiquitous in biomedical applications from basic research to clinical practice. With the rapid increase in resolution, dimensionality of the images and the need for real-time performance in many applications, computational requirements demand proper exploitation of multicore architectures. …”
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Translating Research into Clinical Scale Manufacturing of Mesenchymal Stromal Cells by Karen Bieback, Sven Kinzebach, Marianna Karagianni

“…However, translating basic research into routine therapies is a complex multistep process which necessitates product regulation. …”
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Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Develop... by Elie El Agha, Saverio Bellusci

“…Basic research on embryonic lung development offers unique opportunities to make important discoveries that will impact human health. …”
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Probiotics to Prevent the Need for, and Augment the Use of, Antibiotics by Gregor Reid

“…It is to our discredit that basic research on microbial ecology has been stalled in Canada for the past 20 years. …”
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Can Squid Game Series Be Watched Through Social Darwinism? A Semiotic Review by Hasan Tutar

“…The semiotic method was used in the research due to its suitability for the subject’spurpose, context, and basic research question. The sample of the study was determined according to thepurposive sampling technique. …”
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Author Correction: Siliceous zeolite-derived topology of amorphous silica by Hirokazu Masai, Shinji Kohara, Toru Wakihara, Yuki Shibazaki, Yohei Onodera, Atsunobu Masuno, Sohei Sukenaga, Koji Ohara, Yuki Sakai, Julien Haines, Claire Levelut, Philippe Hébert, Aude Isambert, David A. Keen, Masaki Azuma

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Are in-medium quark-gluon showers strongly coupled? results in the large-N f limit by Peter Arnold, Omar Elgedawy, Shahin Iqbal

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EFFECT OF WIKI AS A TEACHING TOOL ON CRITICAL THINKING AND PERFORMANCE LEVEL OF KATA EMPI IN KARATE FOR UNIVERSITY STUDENTS by Ahmed Almahallawy, Eman Almahallawy, Shady Fathalla

“…Sample from the youth of Al-Arish Sports Club under (16) years old, and it consisted of (20 youths) representing a percentage (87%) of the research community as the basic research sample, and they were divided into two groups, one of which was experimental and consisted of (10 youth). and a control group consisting of (10 youth), and the exploratory study was conducted on a sample of (6 youth) representing a percentage (23%), to conduct the scientific transactions for the tests under discussion, and the researcher excluded the players who mastered the performance of kata (Empi) and their number reached (4 youth). …”
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Intestinal organoids: The path towards clinical application by Hady Yuki Sugihara, Ryuichi Okamoto, Tomohiro Mizutani

“…Despite significant contributions to basic research, challenges remain to develop intestinal organoids into clinical tools for diagnosis, prognosis, and therapy. …”
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Amniotic Fluid Stem Cells: Future Perspectives by Margit Rosner, Katharina Schipany, Bharanidharan Shanmugasundaram, Gert Lubec, Markus Hengstschläger

“…Today, amniotic fluid stem (AFS) cells are widely accepted as a new powerful tool for basic research as well as for the establishment of new stem-cell-based therapy concepts. …”
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Glial cells improve Parkinson’s disease by modulating neuronal function and regulating neuronal ferroptosis by Mengzhu Li, Mengxuan Chen, Haiyan Li, Da Gao, Lijun Zhao, Meiling Zhu

“…This opens up a new pathway for basic research and therapeutic strategies in Parkinson’s disease.…”
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How to increase the prestige of a scientist in the Russian Federation by O. M. Makhalina, V. N. Mahalin

“…Proposals for staffing scientific activities and increasing the prestige of the scientist’s work are formulated: increase of the cost of science; elimination of the problem of the scientific personnel’s aging; significant increase in the material support of the scientific personnel; expansion of the possibilities of using grant financing for basic research. Special attention is paid to solving the tasks of improving scientific activity, which are formulated in national projects.…”
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Lessons to be Learned for Gastroenterology from Recent Issues in Clinical Trial Methodology by C Ohmann, J Albrecht

“…Randomized trials are the preferred tool for patient-oriented research, and their main role is to enable the transfer of results from basic research to routine application. While the need for randomized trials is evident, conducting these trials is becoming increasingly difficult and complex. …”
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