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21
Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes
Published 2016-01-01“…This principle is illustrated by showing how cocaine abuse can alter the adenosine A2AR-dopamine D2R heterocomplexes and their receptor-receptor interactions and hereby induce neural plasticity in the basal ganglia. Studies with A2AR ligands using cocaine self-administration procedures indicate that antagonistic allosteric A2AR-D2R heterocomplexes of the ventral striatopallidal GABA antireward pathway play a significant role in reducing cocaine induced reward, motivation, and cocaine seeking. …”
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22
Structural Correlates of Neurological Signs in Huntington’s Disease: A Quantitative Approach
Published 1994-01-01“…Huntington's disease (HD) is a genetically transmitted disorder associated with atrophy of the basal ganglia. Studies of the neuroanatomical correlates of HD have focused primarily on the anterior areas of the basal ganglia and on establishing an association between structural changes resulting from the presence and course of the illness. …”
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23
Neonatal Brain MRI and Motor Outcome at School Age in Children with Neonatal Encephalopathy: A Review of Personal Experience
Published 2003-01-01“…Motor outcome appears to be mainly related to the severity of basal ganglia and internal capsule involvement. Severe basal ganglia lesions were always associated with the most severe outcome, microcephaly, tetraplegia, and severe global delay, whereas more discrete basal ganglia lesions were associated with athetoid cerebral palsy, with normal cognitive development or minor neuro-motor abnormalities. …”
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24
Methadone-Induced Toxic Brain Damage
Published 2013-01-01“…To our knowledge this is the first reported case of both cerebellar and basal ganglia involvement in methadone overdose.…”
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25
Cerebral Ultrasound at Term-Equivalent Age: Correlations with Neuro-Motor Outcomes at 12–24 Months Corrected Age
Published 2024-12-01“…<b>Methods:</b> The following were assessed: the Levine Index, the diagonals of the lateral ventricles, the size of the ventricular midbody, the sinocortical distance, the width of the basal ganglia, the cortical depth at the level of the cingular sulcus and the maturation of the gyral folding. …”
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26
Predictors and lesion patterns of dysphagia and swallowing outcomes after acute intracerebral hemorrhage
Published 2025-01-01“…Midline shift and basal ganglia hematoma remained independent predictors of impaired swallowing on day 30. …”
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27
Disrupted Auto-Activation, Dysexecutive and Confabulating Syndrome Following Bilateral Thalamic and Right Putaminal Stroke
Published 2008-01-01“…Quantified ECD SPECT revealed bilateral hypoperfusions in the basal ganglia and thalamus but no perfusion deficits were found at the cortical level. …”
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28
Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm
Published 2025-01-01“…This study investigates the functional network underlying response inhibition in the human brain, particularly the role of the basal ganglia in successful action cancellation. Functional magnetic resonance imaging (fMRI) approaches have frequently used the stop-signal task to examine this network. …”
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29
Characterizing Cerebral Imaging and Electroclinical Features of Five Pseudohypoparathyroidism Cases Presenting with Epileptic Seizures
Published 2022-01-01“…Cerebral CT scans showed extensive brain calcifications in the bilateral basal ganglia (all five cases), cerebellum (cases 1, 3, and 5), thalamus (case 4), and cerebral cortex. …”
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30
Caudate Nucleus Volume Mediates the Link between Cardiorespiratory Fitness and Cognitive Flexibility in Older Adults
Published 2012-01-01“…The basal ganglia play a central role in regulating the response selection abilities that are critical for mental flexibility. …”
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31
Histone Deacetylase Inhibitor Scriptaid Alleviated Neurological Dysfunction after Experimental Intracerebral Hemorrhage in Mice
Published 2018-01-01“…An ICH model was constructed by injecting autologous blood into the right basal ganglia in mice. The animals were administered 3.5 mg/kg of Scriptaid intraperitoneally after ICH. …”
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32
The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients
Published 2013-01-01“…Traditionally, the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia. Recently, however, substantial evidence has emerged for cerebellar involvement. …”
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33
Delta opioid receptors affect acoustic features of song during vocal learning in zebra finches
Published 2025-01-01“…Since the opioid and dopaminergic systems interact, we decided to study whether blocking δ-ORs during the sensitive period led to changes in dopaminoceptive neurons in Area X, a song control nucleus in the basal ganglia. Interestingly, compared with controls, naltrindole-treated birds had higher numbers of DARPP-32-positive medium spiny neurons and potentially excitatory synapses in Area X. …”
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34
Machine learning techniques for independent gait recovery prediction in acute anterior circulation ischemic stroke
Published 2025-02-01“…Results Ten predictors were identified through LASSO regression, including age, gender, periventricular white matter hyperintensities (PVWMH), Montreal Cognitive Assessment (MoCA), National Institutes of Health Stroke Scale (NIHSS), enlarged perivascular spaces in basal ganglia (BG-EPVS), lacunes, parietal infarction, basal ganglia infarction, and Timed Up & Go (TUG) test score. …”
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35
Elsevier's Integrated Neuroscience /
Published 2007Table of Contents: “…Cells of the nervous system -- Electrical signaling by nerve cells -- Synaptic transmission -- Sensory receptors -- General organization of the nervous system -- Development of the nervous system -- Tissues supporting the nervous system -- Imaging the nervous system -- Somatosensory system -- Auditory system -- Vestibular system -- Visual system -- Chemical senses -- Motor neurons and motor units -- Basal ganglia -- Cerebellum -- Control of eye movements -- Homeostasis, motivation, and emotion -- Consciousness and cognition -- Formation, maintenance, and plasticity of neuronal connections -- Case studies -- Case study answers.…”
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36
Alterations of Interhemispheric Functional Connectivity and Degree Centrality in Cervical Dystonia: A Resting-State fMRI Study
Published 2019-01-01“…Reports on microstructural and functional abnormalities in multiple brain regions not limited to the basal ganglia have been increasing in patients with CD. …”
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37
Analysis of intracranial lesions in patients with HIV-associated cryptococcal meningitis
Published 2025-02-01“…They often appear as lacunar infarcts, predominantly in the basal ganglia, and can worsen with treatment initiation, possibly due to higher baseline cytokine levels in cerebrospinal fluid.…”
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38
Study on Lesion Assessment of Cerebello-Thalamo-Cortical Network in Wilson’s Disease with Diffusion Tensor Imaging
Published 2017-01-01“…Besides, lesions in the basal ganglia, thalamus, and cerebellum might disconnect the basal ganglia-thalamo-cortical circuits or dentato-rubro-thalamic (DRT) track and disrupt cerebello-thalamo-cortical network finally, which may cause clinical extrapyramidal symptoms.…”
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39
An Updated Overview of the Magnetic Resonance Imaging of Brain Iron in Movement Disorders
Published 2022-01-01“…Specifically, the iron provides most of the paramagnetic metal signals in the brain and its accumulation seems to play a key role, although not completely explained, in the degeneration of the basal ganglia, as well as other brain structures. Moreover, iron distribution patterns have been implicated in depicting different movement disorders. …”
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40
Emotional Processing following Cortical and Subcortical Brain Damage: Contribution of the Fronto-Striatal Circuitry
Published 1998-01-01“…The present study examined the differential contribution of cortical and subcortical brain structures in emotional processing by comparing patients with focal cortical lesions (n = 32) to those with primarily subcortical dysregulation of the basal ganglia (Parkinson’s disease n = 14). A standardized measure of emotional perception (Tübingen Affect Battery) was used. …”
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