Risk factors for hepatocellular carcinoma: an umbrella review of systematic review and meta-analysis by Jie Wang, Kaijie Qiu, Songsheng Zhou, Yichao Gan, Keting Jiang, Donghuan Wang, Haibiao Wang

“…Smoking, obesity, non-alcoholic fatty liver disease, diabetes, low platelet, elevated liver enzymes and liver fluke infection increase HCC risk, while coffee consumption, a healthy diet, and bariatric surgery lower it. Medications like metformin, glucagon-like peptide-1 receptor agonists (GLP-1 RAs), aspirin, statins, and selective serotonin reuptake inhibitors reduce HCC risk, while acid suppressive agents, particularly proton pump inhibitors, elevate it. …”
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Semaglutide and laparoscopic sleeve gastrectomy in an adolescent with congenital adrenal hyperplasia due to 21-hydroxylase: a case report by Alaina P. Vidmar, Linus Kaiser, Matthew J. Martin, Stuart Abel, Aimee G. Kim, Madeleine Weitzner, Cynthia E. Muñoz, Lynda K. Fisher, Mimi S. Kim, Kamran Samakar

“…The successful outcomes from both pharmacotherapy and bariatric surgery suggest that tailored obesity management strategies can optimize health in this unique population, reinforcing the need for further research into comprehensive obesity care in individuals with congenital adrenal hyperplasia.…”
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Mouse Models of Nonalcoholic Steatohepatitis: Head-to-Head Comparison of Dietary Models and Impact on Inflammation and Animal Welfare by Andreas Kroh, Vanina Ivanova, Hannah Drescher, Julia Andruszkow, Thomas Longerich, Jochen Nolting, Roman Eickhoff, D. Heise, Karl P. Rheinwalt, Ulf P. Neumann, Florian T. Ulmer

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Quantile-Dependent Expressivity of Serum Uric Acid Concentrations by Paul T. Williams

“…This is consistent with the larger genetic effect size of (1) the SLC2A9 rs11722228 polymorphism in gout patients vs. controls, (2) the ABCG2 rs2231142 polymorphism in men vs. women, (3) the SLC2A9 rs13113918 polymorphism in obese patients prior to bariatric surgery vs. two-year postsurgery following 29 kg weight loss, (4) the ABCG2 rs6855911 polymorphism in obese vs. nonobese women, and (5) the LRP2 rs2544390 polymorphism in heavier drinkers vs. abstainers. …”
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Comparison of clinician- and patient-reported outcome measures in 95 abdominoplasty cases using BODY-Q and MCCRO-Q by Samuel Thomas Kitching, Claudia Rocco, Rachel Harwood, Gary Ross

“…Clinicians reported better outcomes in patients who achieved massive weight loss through diet and exercise as opposed to bariatric surgery (p=0.044). Patients who underwent concomitant surgical operation had significantly improved clinician-scored outcomes (p=0.047), and patients with post-operative complications achieved worse clinician-scored outcomes (p=0.036). …”
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Combined detection of inflammatory proteins is beneficial for diagnosing the papillary thyroid carcinoma and nodular goiter by Yongqin Pan, Mingxi Xu, Tsz Hong Chong, Siping Xie, Kunsong Huang, Guanghao Wang, Yuhua Ma, Jinyi Li, Wah Yang

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Prevention Of Breast and Endometrial cancer using Total Diet Replacement (PROBE-TDR) trial: protocol for a randomised controlled trial by Robert Clarke, Emma J Crosbie, Basil G Issa, John Belcher, Helen Clarke, Anthony Howell, Michelle Harvie, Hannah Harrison, Cheryl Lombardelli, Suzanne Krizak, Katharine Sellers, Yit Y Lim, Caroline Parkin, Shruthi Patel, Anthony J Maxwell, Julie Wisely, Sacha J Howell

“…Introduction Obesity and overweight are strong potentially modifiable risk factors for postmenopausal breast and endometrial cancer. Bariatric surgery can achieve considerable weight loss and risk reduction of weight-related cancer but is unlikely to be a feasible cancer prevention strategy. …”
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Socio-Demographic and Preoperative Clinical Factors Associated With 5-Year Weight Trajectories After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy by Sahil Patel, MD, Chen Jiang, PhD, Brandon Cowan, MD, Jie Yin, MS, Catherine Schaefer, PhD, Sanjoy Dutta, MD, Rouzbeh Mostaedi, MD, Hélène Choquet, PhD

“…To determine whether socio-demographic and preoperative clinical factors contribute to the percent total body weight loss (%TBWL) after bariatric surgery (BS). Background:. BS is the most effective long-term treatment for medically complicated obesity. …”
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A woman’s place is in theatre: women’s perceptions and experiences of working in surgery from the Association of Surgeons of Great Britain and Ireland women in surgery working grou... by Maria Irene Bellini, Yitka Graham, Catherine Hayes, Roxanna Zakeri, Rowan Parks, Vassilios Papalois

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Nutritional and General Awareness of Vitamin D Status among Adult Population in Sulaymaniyah Governorate, Kurdistan Region, Iraq: A Cross-Sectional Study by Reder Rafiq Mohammed Salih, Fadhluddin Nasruddin Shakor, Dalia Ardal Ali, Rafiq Mohammed Salih Rashid

“…In addition, less than 10% of individuals attributed vitamin D shortage to kidney and liver problems, fat malabsorption, obesity, and bariatric surgery. Nevertheless, more than two-thirds (83.3%) of participants defined the positive role of vitamin D in preventing osteoporosis and immune system strengthening (61%). …”
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Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis by Sergio Bergese, Richard Berkowitz, Paul Rider, Martin Ladouceur, Suzanne Griffith, Alvaro Segura Vasi, Kristina Cochrane, Linda Wase, Mark A. Demitrack, Ashraf S. Habib

“…Patients at 18 years of age or older, who underwent colorectal, orthopedic, cardiothoracic, bariatric, or general surgeries between June 2015 and May 2017 in 11 sites participating in the ATHENA trial who received postoperative analgesia either with IV oliceridine or with IV conventional opioids (e.g., morphine alone or in combination with other opioids) (CO cohort); and had a hospital stay >48 hours, were included in this retrospective analysis. …”
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Serum Lactate Dehydrogenase Is a Novel Predictor for the Severity in the Patients With MAFLD: A Cross-Sectional Study in Hefei, China by Yu L, Bao S, Zhu F, Xu Y, Zu F, Liu Y, Jiang R, Chen S, Chen W

“…Liang Yu,1,* Shiming Bao,2,* Feng Zhu,3,* Yanyan Xu,1 Fuqiang Zu,1 Yanwei Liu,1 Runbeng Jiang,1 Wei Chen,4 Song Chen5 1Department of General Surgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department of Emergency Surgery, Tongling People’s Hospital, Tongling, People’s Republic of China; 3Department of General Surgery, Tongling People’s Hospital, Tongling, People’s Republic of China; 4Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 5Department of General Surgery, the Affiliated Chuzhou Hospital of Anhui Medical University (The First People’s Hospital of Chuzhou), Chuzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Song Chen, Department of General Surgery, the Affiliated Chuzhou Hospital of Anhui Medical University (The First People’s Hospital of Chuzhou), Chuzhou, People’s Republic of China, Email chensong101425@163.com Wei Chen, Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China, Email 13665560109@163.comBackground & Aims: The aim of this study was to assess the association between the level of lactate dehydrogenase (LDH) and the severity of metabolic syndrome (MetS) and Metabolic Associated Fatty Liver Disease (MAFLD) and the potential diagnostic value of LDH for identifying at-risk metabolic associated steatohepatitis (MASH).Methods: This cross-sectional, real-world retrospective study enrolled a total of 1118 obese patients in the department of bariatric surgery at the Second Affiliated Hospital of Anhui Medical University from January 1, 2018, to December 31, 2021. …”
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Surgeon Preference and Clinical Outcome of 3D Vision Compared to 2D Vision in Laparoscopic Surgery: Systematic Review and Meta-Analysis of Randomized Trials by Rawin Amiri, BSc, Maurice J. W. Zwart, PhD, Leia R. Jones, BSc, Mohammad Abu Hilal, PhD, FRCS, Harrie P. Beerlage, PhD, FEBU, Mark I. van Berge Henegouwen, PhD, Wytze W. Lameris, PhD, Willem A. Bemelman, PhD, Marc G. Besselink, MD, MSc, PhD

“…This benefit was mostly seen in bariatric surgery (−16.3%; 95% CI, −1.28 to −0.21; P = 0.006; 2 studies; n = 58; I2 = 0%) and general surgery (−6.7%; 95% CI, −0.34 to −0.01; P = 0.036; 9 studies; n = 1056; I2 = 41%). …”
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Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis by Beatriz Cicuéndez, Alfonso Mora, Juan Antonio López, Andrea Curtabbi, Javier Pérez-García, Begoña Porteiro, Daniel Jimenez-Blasco, Pedro Latorre-Muro, Paula Vo, Madison Jerome, Beatriz Gómez-Santos, Rafael Romero-Becerra, Magdalena Leiva, Elena Rodríguez, Marta León, Luis Leiva-Vega, Noemi Gómez-Lado, Jorge L. Torres, Lourdes Hernández-Cosido, Pablo Aguiar, Miguel Marcos, Martin Jastroch, Andreas Daiber, Patricia Aspichueta, Juan Pedro Bolaños, Jessica B. Spinelli, Pere Puigserver, José Antonio Enriquez, Jesús Vázquez, Cintia Folgueira, Guadalupe Sabio

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Sucrose-preferring gut microbes prevent host obesity by producing exopolysaccharides by Hidenori Shimizu, Junki Miyamoto, Keiko Hisa, Ryuji Ohue-Kitano, Hiromi Takada, Mayu Yamano, Akari Nishida, Daiki Sasahara, Yuki Masujima, Keita Watanabe, Shota Nishikawa, Sakura Takahashi, Takako Ikeda, Yuya Nakajima, Naofumi Yoshida, Chiaki Matsuzaki, Takuya Kageyama, Ibuki Hayashi, Akari Matsuki, Ryo Akashi, Seiichi Kitahama, Masako Ueyama, Takumi Murakami, Shinsuke Inuki, Junichiro Irie, Noriko Satoh-Asahara, Hirokazu Toju, Hiroshi Mori, Shinji Nakaoka, Tomoya Yamashita, Atsushi Toyoda, Kenji Yamamoto, Hiroaki Ohno, Takane Katayama, Hiroshi Itoh, Ikuo Kimura

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Global burden of metabolic dysfunction-associated steatotic liver disease, 2010 to 2021 by Gong Feng, Giovanni Targher, Christopher D. Byrne, Yusuf Yilmaz, Vincent Wai-Sun Wong, Cosmas Rinaldi Adithya Lesmana, Leon A. Adams, Jerome Boursier, George Papatheodoridis, Mohamed El-Kassas, Nahum Méndez-Sánchez, Silvia Sookoian, Laurent Castera, Wah-Kheong Chan, Feng Ye, Sombat Treeprasertsuk, Helena Cortez-Pinto, Hon Ho Yu, Won Kim, Manuel Romero-Gómez, Atsushi Nakajima, Khin Maung Win, Seung Up Kim, Adriaan G. Holleboom, Giada Sebastiani, Ponsiano Ocama, John D. Ryan, Monica Lupșor-Platon, Hasmik Ghazinyan, Mamun Al-Mahtab, Saeed Hamid, Nilanka Perera, Khalid A. Alswat, Qiuwei Pan, Michelle T. Long, Vasily Isakov, Man Mi, Marco Arrese, Arun J. Sanyal, Shiv Kumar Sarin, Nathalie Carvalho Leite, Luca Valenti, Philip N. Newsome, Hannes Hagström, Salvatore Petta, Hannele Yki-Järvinen, Jörn M. Schattenberg, Marlen I. Castellanos Fernández, Isabelle A. Leclercq, Gulnara Aghayeva, Abdel-Naser Elzouki, Ali Tumi, Ala I. Sharara, Asma Labidi, Faisal M. Sanai, Khaled Matar, Maen Al-Mattooq, Maisam Waid Akroush, Mustapha Benazzouz, Nabil Debzi, Maryam Alkhatry, Salma Barakat, Said A. Al-Busafi, John Rwegasha, Wah Yang, Agyei Adwoa, Christopher Kenneth Opio, Mohammadjavad Sotoudeheian, Yu Jun Wong, Jacob George, Ming-Hua Zheng

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