Exosomes: new targets for understanding axon guidance in the developing central nervous system by Mingyu Liu, Mingyu Liu, Teng Teng, Teng Teng, Teng Teng

Subjects: “…axon guidance…”
Get full text

Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury by Ping Li, Zhao-Qian Teng, Chang-Mei Liu

“…This article reviews the role and mechanism of differentially expressed microRNAs in regulating axon regeneration and glial scar formation after spinal cord injury, as well as their therapeutic potential for promoting axonal regeneration and repair of the injured spinal cord.…”
Get full text

Wave fronts in neuronal fields with nonlocalpost-synaptic axonal connections and delayed nonlocal feedbackconnections by Felicia Maria G. Magpantay, Xingfu Zou

“…We consider a neuronal network model with both axonal connections (in the form ofsynaptic coupling) and delayed non-local feedback connections. …”
Get full text

CRMP2 and CRMP4 Are Differentially Required for Axon Guidance and Growth in Zebrafish Retinal Neurons by Zhi-Zhi Liu, Jian Zhu, Chang-Ling Wang, Xin Wang, Ying-Ying Han, Ling-Yan Liu, Hong A. Xu

“…Axons are directed to their correct targets by guidance cues during neurodevelopment. …”
Get full text

Mimicking Axon Growth and Pruning by Photocatalytic Growth and Chemical Dissolution of Gold on Titanium Dioxide Patterns by Fatemeh Abshari, Moritz Paulsen, Salih Veziroglu, Alexander Vahl, Martina Gerken

“…Axon pruning, i.e., the removal of exuberant axonal connections, is essential in network remodeling. …”
Get full text

Reactivation of Denervated Schwann Cells by Embryonic Spinal Cord Neurons to Promote Axon Regeneration and Remyelination by Xinyu Fang, Chaofan Zhang, Chongjing Zhang, Yuanqing Cai, Zibo Yu, Zida Huang, Wenbo Li, Wenming Zhang

“…Thus, the neurons play the role of proximal axons to prevent chronic degeneration and fibrosis of SCs. …”
Get full text

Gap junction intercellular communications regulates activation of SARM1 and protects against axonal degeneration by Wen Jie Zhu, Jun Liu, Wan Hua Li, Zhi Ying Zhao, Chongquan Huang, Jian Yuan Yang, Hon Cheung Lee, Yong Juan Zhao

“…Abstract Sterile alpha and Toll/interleukin-1 receptor motif containing 1 (SARM1), a nicotinamide adenine dinucleotide (NAD)-utilizing enzyme, mediates axon degeneration (AxD) in various neurodegenerative diseases. …”
Get full text

Small Extracellular Vesicles Promote Axon Outgrowth by Engaging the Wnt-Planar Cell Polarity Pathway by Samar Ahmad, Tania Christova, Melanie Pye, Masahiro Narimatsu, Siyuan Song, Jeffrey L. Wrana, Liliana Attisano

Subjects: Get full text

The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury by Shmma Quraishe, Lindsey H. Forbes, Melissa R. Andrews

“…After injury, however, CSPGs and tenascins contribute to the structure of the inhibitory glial scar, which actively prevents axonal regeneration. Myelin sheaths and mature adult oligodendrocytes, despite their important role in signal conduction in mature CNS axons, contribute to the inhibitory environment existing after injury. …”
Get full text

Low-Dose Taxol Promotes Neuronal Axons Extension and Functional Recovery after Spinal Cord Injury by Baoguo Liu, Sumei Liu, Dejun Sun

“…The growth and extension of neuronal axons is a dynamic biological process mediated by the cytoskeleton, and microtubule plays an important role in axonal growth. …”
Get full text

AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury by Wen-Yuan Li, Ying Wang, Feng-Guo Zhai, Ping Sun, Yong-Xia Cheng, Ling-Xiao Deng, Zhen-Yu Wang

“…DPSN axons mediate and maintain a variety of normal spinal functions. …”
Get full text

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats by Marta Zaforas, Esther Benayas, Raquel Madroñero-Mariscal, Ana Domínguez-Bajo, Elena Fernández-López, Yasmina Hernández-Martín, Ankor González-Mayorga, Elena Alonso-Calviño, Eduardo R. Hernández, Elisa López-Dolado, Juliana M. Rosa, Juan Aguilar, María C. Serrano

“…Together with histological features at the lesion site, such as more abundant and larger blood vessels and more abundant, longer and more homogeneously distributed axons, our results corroborate that rGO scaffolds create a permissive environment that allows the invasion of functional axonic processes from neurons located in brainstem nuclei with motor function in a rat model of complete thoracic transection. …”
Get full text

GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand by Tomoaki Suzuki, Ken Kadoya, Takeshi Endo, Miwako Yamasaki, Masahiko Watanabe, Norimasa Iwasaki

Subjects: “…axon regeneration…”
Get full text

Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

Get full text

Fluorescent identification of axons, dendrites and soma of neuronal retinal ganglion cells with a genetic marker as a tool for facilitating the study of neurodegeneration by Puttipong Sripinun, Wennan Lu, Sergei Nikonov, Suhani Patel, Sarah Hennessy, Tianyuan Yao, Qi N. Cui, Brent A. Bell, Claire H. Mitchell

Subjects: “…axons…”
Get full text

CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation by Minghui Tan, Caihui Cha, Yongheng Ye, Jifeng Zhang, Sumei Li, Fengming Wu, Sitang Gong, Guoqing Guo

“…CRMP2 and CRMP4 also interacted with one another coordinately to promote growth cone development and axonal elongation. Genetic silencing of CRMP2 enhanced, whereas overexpression of CRMP2 suppressed, the inhibitory effects of CRMP4 knockdown on axonal development. …”
Get full text

GPX modulation promotes regenerative axonal fusion and functional recovery after injury through PSR-1 condensation by Su-Hyuk Ko, Kyung-Ah Cho, Xin Li, Qitao Ran, Zhijie Liu, Lizhen Chen

“…Abstract Axonal fusion represents an efficient way to recover function after nerve injury. …”
Get full text

Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats by Yonglin Zhao, Yahui Zhao, Ming Zhang, Junjie Zhao, Xudong Ma, Tingqin Huang, Honggang Pang, Jiaxi Li, Jinning Song

“…Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. …”
Get full text

Involvement of Toll Like Receptor 2 Signaling in Secondary Injury during Experimental Diffuse Axonal Injury in Rats by Yonglin Zhao, Junjie Zhao, Ming Zhang, Yahui Zhao, Jiaxi Li, Xudong Ma, Tingqin Huang, Honggang Pang, Bo Wang, Jinning Song

“…Treatment of diffuse axonal injury (DAI) remains challenging in clinical practice due to the unclear pathophysiological mechanism. …”
Get full text

A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient by Uchechukwu Ibewuike, MBBS, John Kim, MD, Swati Mody, MBBS, Gregory Obala, MD, Ebere Ibezim, MBBS

Subjects: “…Acute motor axonal neuropathy…”
Get full text