Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model by Musaad A. Alshammari, Mohammad R. Khan, Fawaz Alasmari, Abdulaziz O. Alshehri, Rizwan Ali, Mohamed Boudjelal, Khalid A. Alhosaini, Abdurahman A. Niazy, Tahani K. Alshammari

“…The axon initial segment (AIS), the site of action potential initiation in neurons, is a critical determinant of neuronal excitability. …”
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Diabetes insipidus and Guillain-Barré-like syndrome following CAR-T cell therapy: a case report by Christian Koch, Patrick Roth, Juliane Fleischer, Todor Popov, Karl Frontzek, Bettina Schreiner, Markus G. Manz, Simone Unseld, Antonia M. S. Müller, Norman F. Russkamp

“…Muscle-nerve biopsy and nerve conduction studies confirmed an axonal pattern of nerve damage. T cell-rich infiltrates and detection of the CAR transgene in muscle-nerve sections imply a direct or indirect role of CAR-T cell-mediated inflammation. …”
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Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy by Zekai Cui, Xiaoxue Li, Yiwen Ou, Xihao Sun, Jianing Gu, Chengcheng Ding, Zhexiong Yu, Yonglong Guo, Yuqin Liang, Shengru Mao, Jacey Hongjie Ma, Hon Fai Chan, Shibo Tang, Jiansu Chen

“…Transcriptomic analysis revealed that HG downregulated genes associated with axon and synapse formation while upregulating immune response and oxidative stress pathways, with C-C Motif Chemokine Ligand 5 (CCL5) identified as a key hub gene in DK pathogenesis. …”
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Evolution in optical molecular imaging techniques guided nerve imaging from 2009 to 2023: a bibliometric and visualization analysis by Wenkai Liang, Yan Liu, Erlong Jia, Xiaofeng Yang, Shufeng Han, Jinzheng Wei, Jinzheng Wei, Wei Zhao

“…The main cluster of keywords in this field includes “axonal regeneration,” “mouse,” and “optical coherence tomography.”ConclusionThis bibliometric investigation offers a comprehensive portrayal of the structure of knowledge and the progression patterns, presents an all-encompassing synthesis of findings, discerns and illustrates the forefront within OMI guided nerve imaging for the first time. …”
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Decoding cyanide toxicity: Integrating Quantitative Structure-Toxicity Relationships (QSTR) with species sensitivity distributions and q-RASTR modeling by Kabiruddin Khan, Ramin Abdullayev, Gopala Krishna Jillella, Varun Gopalakrishnan Nair, Mahmoud Bousily, Supratik Kar, Agnieszka Gajewicz-Skretna

“…Key molecular descriptors, including topological, geometrical, and electronic properties, were computed using ALOGPS 2.1, ChemAxon, and Elemental-Descriptor 1.0. Three machine learning methods MLR, PLS, and kNN were employed to develop predictive models. …”
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Spinal Reflex Recovery after Dorsal Rhizotomy and Repair with Platelet-Rich Plasma (PRP) Gel Combined with Bioengineered Human Embryonic Stem Cells (hESCs) by Mateus Vidigal de Castro, Moníze Valéria Ramos da Silva, Gabriela Bortolança Chiarotto, Maria Helena Andrade Santana, Ângela Cristina Malheiros Luzo, Sergiy Kyrylenko, Alexandre Leite Rodrigues de Oliveira

“…Altogether, the results indicate that the combination of hESCs with PRP gel promoted substantial and prominent axonal regeneration processes after DRZ. Thus, the repair of dorsal roots, if done appropriately, may be considered an approach to regain sensory-motor function after dorsal root axotomy.…”
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An Unusual Case of Peripheral Nerve Vasculitis by S. Wang, Arsany A., D. Feinstein, P. Traisak, H. Eid, M. Karpoff

“…EMG showed distal, symmetric, and axonal polyneuropathy affecting the upper and lower extremities and acute denervation in more distal muscles. …”
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Neuroplasticidad en adolescente con agenesia del cuerpo calloso asociado a epilepsia by Dámaris González Vidal, Osvaldo Ramón Aguilera Pacheco, Margarita Isabel Chávez Isla

“…La agenesia del cuerpo calloso es una malformación del sistema nervioso central que se produce por falta del desarrollo o del entrecruzamiento de los axones provenientes de la corteza cerebral, lo que puede asociarse a otras malformaciones o ser producto de lesiones destructivas con atrofia. …”
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Electroacupuncture-Regulated miR-34a-3p/PDCD6 Axis Promotes Post-Spinal Cord Injury Recovery in Both In Vitro and In Vivo Settings by Lili Ma, Lizhong Ma, Yu Yang, Ting Chen, Limin Wang, Qilong Deng

“…Notably, in the post-SCI rat model, exogenous miR-34a-3p agomir obviously inhibited the expression of PDCD6 at the protein level and promoted neuronal proliferation, motoneurons regeneration, and axonal myelination. The restorations at cellular level might contribute to the improved hindlimbs functions of post-SCI rats, which was manifested by the Basso-Beattie-Bresnahan (BBB) locomotor test. …”
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Construction of an lncRNA-mediated ceRNA network to investigate the inflammatory regulatory mechanisms of ischemic stroke. by Meimei Xu, Shan Yuan, Xing Luo, Mengsi Xu, Guangze Hu, Zhe He, Xinyuan Yang, Rui Gao

“…These molecules were shown to participate extensively in post-stroke processes, including angiogenesis, axonal regeneration, inflammatory responses, microglial activation, blood-brain barrier (BBB) disruption, apoptosis, autophagy, ferroptosis, and thrombocytopenia. …”
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Aspectos clínicos y epidemiológicos del síndrome de Guillain-Barré by Jhofre Ariel Cedeño Laz

“…Las variantes más comunes de este síndrome son la polineuropatía inflamatoria aguda desmielinizante y la neuropatía axonal motora aguda, ambos con características clínicas diferentes. …”
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Intraparenchymal Neural Stem/Progenitor Cell Transplantation for Ischemic Stroke Animals: A Meta-Analysis and Systematic Review by Hailong Huang, Kun Qian, Xiaohua Han, Xin Li, Yifeng Zheng, Zhishui Chen, Xiaolin Huang, Hong Chen

“…Intriguingly, endogenous apoptosis inhibition and axonal regeneration played the most critical role in intraparenchymal NSPC transplantation among the cellular mechanisms. …”
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Evaluation of transcriptomic changes after photobiomodulation in spinal cord injury by Andrew R. Stevens, Mohammed Hadis, Hannah Alldrit, Michael R. Milward, Valentina Di Pietro, Deena M. A. Gendoo, Antonio Belli, William Palin, David J. Davies, Zubair Ahmed

“…Abstract Spinal cord injury (SCI) is a significant cause of lifelong disability, with no available disease-modifying treatments to promote neuroprotection and axon regeneration after injury. Photobiomodulation (PBM) is a promising therapy which has proven effective at restoring lost function after SCI in pre-clinical models. …”
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Post-traumatic pituitary stalk transection syndrome (PSTS) expeditiously manifested after a fall from a height combined with acute traumatic spinal cord injury: a rare case report... by Yohei Ishiki, Atsuko Tamaki, Ken-ichiro Honma, Ken Yonaha, Takamitsu Yabiku, Taiki Teruya, Moriyuki Uehara, Yoshiro Nakayama, Rei Chinen, Tsugumi Uema, Sawako Nakachi, Shiki Okamoto, Hiroaki Masuzaki

“…MRI revealed loss of the pituitary stalk, whilst the hyperintense signal from distal axon of hypothalamus was still identified. Based on these findings, she was diagnosed as PSTS. …”
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White matter hyperintensities and cholinergic degeneration as Lewy body disease by Sungwoo Kang, Seun Jeon, Yeoju Kim, Su‐Hee Jeon, Minsun Choi, Young‐gun Lee, Mijin Yun, Byoung Seok Ye

“…Anterior periventricular WMHs may represent axonal alterations caused by the interplay between Lewy body‐related degeneration and vascular pathologies.…”
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Acute therapeutic effects and pathophysiology of eosinophilic granulomatosis with polyangiitis neuropathy by Fumitaka Shimizu, Mariko Oishi, Toshihiko Maeda, Yukio Takeshita, Hideaki Nishihara, Ryota Sato, Takashi Kanda, Masayuki Nakamori, Michiaki Koga, Miwako Fujisawa, Yuki Mizumoto, Nanami Yamanaka, Takashi Nawata, Tatsuya Okafuji, Susumu Fujikawa, Kinya Matsuo, Joe Nemoto, Masaya Honda

“…Intrafascicular oedema was found in 95% of all patients.Discussion Our results suggest three pathological pathways: (1) ischaemic peripheral nerve due to vasculitis mainly in ANCA-positive cases, (2) direct infiltration and degranulation of eosinophils in ANCA-negative cases and (3) progression of axonal ischaemia due to intrafascicular oedema in both cases. …”
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Understanding Autoimmune Mechanisms in Multiple Sclerosis Using Gene Expression Microarrays: Treatment Effect and Cytokine-related Pathways by A. Achiron, M. Gurevich, D. Magalashvili, I. Kishner, M. Dolev, M. Mandel

“…Multiple sclerosis (MS) is a central nervous system disease in which activated autoreactive T-cells invade the blood brain barrier and initiate an inflammatory response that leads to myelin destruction and axonal loss. The etiology of MS, as well as the mechanisms associated with its unexpected onset, the unpredictable clinical course spanning decades, and the different rates of progression leading to disability over time, remains an enigma. …”
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Application of stem cells alone and in combination with low-level laser therapy for sciatic nerve repair in rats by Mohsen Shalalvand, Hamidreza Mahaseni Aghdam, Ahmad Asghari, Siamak Nehzat, Fatemeh Shahsavari, Rojin Ardalani

“…At both 5 and 12 weeks, axonal count and nerve repair scores showed no significant differences among the three groups (P > 0.05). …”
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Alterations of Dopamine-Related Transcripts in A11 Diencephalospinal Pathways after Spinal Cord Injury by Shunyi Zhao, Jaclyn H. DeFinis, Shaoping Hou

“…However, dopamine-β-hydroxylase (DBH), D1 receptors, and DA-associated transcription factors did not change following SCI. Furthermore, axon degeneration below the lesion substantially reduced mRNA levels of TH and D2 in the L1 spinal segment. …”
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Polarity and migration of cranial and cardiac neural crest cells: underlying molecular mechanisms and disease implications by Esteban Salinas, Esteban Salinas, Francis Ruano-Rivadeneira, Juan Ignacio Leal, Teresa Caprile, Marcela Torrejón, Cecilia Arriagada, Cecilia Arriagada

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