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181
Myocarditis with neurological and dermatological involvement in idiopathic Hypereosinophilic syndrome: Case report
Published 2025-03-01“…The clinical manifestations are highly variable, ranging from mild or asymptomatic presentations to acute fulminant myocarditis or chronic restrictive cardiomyopathy.We report a case of idiopathic hypereosinophilic syndrome, characterized by eosinophilic myocarditis, alongside axonal and dermatological involvement. During the follow-up period, the patient demonstrated significant clinical and echocardiographic improvement under corticotherapy and heart failure management, including normalization of eosinophil counts.…”
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182
Management of Cerebellar Tonsillar Herniation following Lumbar Puncture in Idiopathic Intracranial Hypertension
Published 2015-01-01“…We hypothesize that the changes in brain compliance that are thought to occur in the setting of idiopathic intracranial hypertension are protective against further neuronal injury due to axonal stretch following decompressive craniectomy.…”
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183
The role of olfactory transport in the penetration of manganese oxide nanoparticles from blood into the brain
Published 2019-07-01“…In this study, we show a significant contribution of axonal transport to NP accumulation patterns in the brain, both from the nasal cavity and from the vascular bed. …”
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184
Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells
Published 2025-01-01“…Enrichment of pathways related to neurogenesis, axon guidance, and synaptic signaling varied across donors, highlighting the impact of genetic and epigenetic individuality on NSPC behavior.…”
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185
The Role of Optical Coherence Tomography Angiography in Optic Nerve Head Edema: A Narrative Review
Published 2022-01-01“…ONH vessel abnormalities are among the earliest signs of impaired axonal transportation. Optical coherence tomography angiography (OCTA) is a noninvasive method for imaging ONH and peripapillary vessels and has been used extensively for studying vascular changes in ONH disorders, including ONH edema. …”
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186
Chemokines and Chemokine Receptors in Multiple Sclerosis
Published 2014-01-01“…Multiple sclerosis is an autoimmune disease with classical traits of demyelination, axonal damage, and neurodegeneration. The migration of autoimmune T cells and macrophages from blood to central nervous system as well as the destruction of blood brain barrier are thought to be the major processes in the development of this disease. …”
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187
Biomarkers of Guillain-Barré Syndrome: Some Recent Progress, More Still to Be Explored
Published 2015-01-01“…Guillain-Barré syndrome (GBS), the axonal subtype of which is mainly triggered by C. jejuni with ganglioside-mimicking lipooligosaccharides (LOS), is an immune-mediated disorder in the peripheral nervous system (PNS) accompanied by the disruption of the blood-nerve barrier (BNB) and the blood-cerebrospinal fluid barrier (B-CSF-B). …”
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188
Arachidonic Acid Derivatives and Their Role in Peripheral Nerve Degeneration and Regeneration
Published 2012-01-01“…After peripheral nerve injury, a process of axonal degradation, debris clearance, and subsequent regeneration is initiated by complex local signaling, called Wallerian degeneration (WD). …”
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189
Optic neuritis and multiple sclerosis association
Published 2020-09-01“…Typical ON is often associated with MS due to the predominant inflammation and demyelination processes in the brain leading to axonal loss. The close relation between these two conditions in etiology and pathogenesis is a key to finding the earliest and the most accurate diagnostic possibilities, which is linked to a better understanding of the ongoing mechanisms. …”
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190
NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway
Published 2025-01-01“…We quantified retinal ganglion cell (RGC) density and optic nerve axonal degeneration, gliosis, and T-cell infiltration in Nlrx1 −/− and wild-type (WT) EAE mice and found increased RGC loss and axonal injury in Nlrx1 −/− mice compared to WT mice in both active immunization EAE and spontaneous opticospinal encephalomyelitis (OSE) models. …”
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191
A case of familial systemic sclerosis
Published 2024-12-01“…We present the case of a 27-year-old male who was examined and found to have bilateral sensory axonal neuropathy, proximal muscle weakness and limb abnormality. …”
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192
Modeling the Encephalopathy of Prematurity in Animals: The Important Role of Translational Research
Published 2012-01-01“…Nevertheless, animal models that simultaneously address oligodendrocyte, neuronal, and axonal injury carry the potential to decipher shared mechanisms and synergistic treatments to ameliorate the global consequences of the encephalopathy of prematurity.…”
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193
An MRI Deep Brain Adult Template With An Advanced Atlas-Based Tool For Diffusion Tensor Imaging Analysis
Published 2024-11-01“…It is open-source and gives users high resolution image datasets to describe nuclear-based and axonal architecture, combining pioneering and recent knowledge. …”
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194
T118M Variant of PMP22 Gene Presents with Painful Peripheral Neuropathy and Varying Charcot-Marie-Tooth Features: A Case Series and Review of the Literature
Published 2018-01-01“…Electrophysiological studies revealed polyneuropathy with axonal and demyelinating features in one case, but there were minimal electrophysiological changes in the other two cases. …”
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195
Influences of physical stimulations on the migration and differentiation of Schwann cells involved in peripheral nerve repair
Published 2025-12-01“…At the tissue level, axonal regeneration has become a research spotlight in peripheral nerve repair. …”
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196
Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM
Published 2025-01-01“…Abstract Netrin-1 (NTN1) is a laminin-related secreted protein involved in axon guidance and cell migration. Previous research has established a significant connection between NTN1 and nervous system development. …”
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197
The Citron homology domain of MAP4Ks improves outcomes of traumatic brain injury
Published 2025-11-01“…The mitogen-activated protein kinase kinase kinase kinases (MAP4Ks) signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following insults. …”
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198
Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia
Published 2025-01-01“…High-resolution live imaging reveals that caspase-3 activation promotes synapse-selective complement-dependent microglial phagocytosis without axonal shearing. Furthermore, activity-dependent caspase-3 activation at inhibitory presynapses induces microglial phagocytosis in mice and increases seizure susceptibility. …”
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199
A riboflavin-responsive neuronopathy with unique characteristics: Brown-Vialetto- Van Laere syndrome
Published 2022-06-01“… Brown-Vialetto-Van Laere syndrome (BVVLS) is a rare disease characterized by progressive axonal neuropathy, optic atrophy, hearing loss, bulbar dysfunction, and respiratory failure associated with mutations in the SLC52A2 and SLC52A3 genes that code for the human riboflavin transporters RFVT2 and RFVT3, respectively. …”
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200
A riboflavin-responsive neuronopathy with unique characteristics: Brown-Vialetto- Van Laere syndrome
Published 2022-06-01“… Brown-Vialetto-Van Laere syndrome (BVVLS) is a rare disease characterized by progressive axonal neuropathy, optic atrophy, hearing loss, bulbar dysfunction, and respiratory failure associated with mutations in the SLC52A2 and SLC52A3 genes that code for the human riboflavin transporters RFVT2 and RFVT3, respectively. …”
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