Axon regeneration: an issue of translation by Schaeffer, Julia, Belin, Stephane

Subjects: “…Axon regeneration…”
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Sporadic ALS hiPSC-derived motor neurons show axonal defects linked to altered axon guidance pathways by Lisha Ye, Katarina Stoklund Dittlau, Adria Sicart, Rekin'’s Janky, Philip Van Damme, Ludo Van Den Bosch

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Axon Guidance Mechanisms for Establishment of Callosal Connections by Mitsuaki Nishikimi, Koji Oishi, Kazunori Nakajima

“…Midline populations express and secrete guidance molecules, and “pioneer” axons as well as interactions between the medial and lateral axons are also involved in the axon pathfinding of the callosal neurons. …”
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Automated quantification of axonal and myelin changes in contusion, dislocation, and distraction spinal cord injuries: Insights into targeted remyelination and axonal regeneration by Xuan Li, Yuan He, Fangyao Chen, Xin Tong, Yunlong Fan, Yuzhe Langzhou, Jie Liu, Kinon Chen

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Axonal excitability and conduction alterations caused by levobupivacaine in rat by Tuncer Seçkin, Tuncer Peker Tülay, Burat İlksen, Kiziltan Erhan, İlhan Barkin, Dalkiliç Nizamettin

“…In this study, effects of the long-acting amide-type local anesthetic levobupivacaine on axonal conduction and excitability parameters of the rat sciatic nerve were thoroughly examined both in vitro and in vivo. …”
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The stability of stationary fronts for a discrete nerve axon model by Christopher E. Elmer

“…We consider the stability of single-front stationary solutions to a spatially discrete reaction-diffusion equation which models front propagation in a nerve axon. The solution's stability depends on the coupling parameter, changing from stable to unstable and from unstable to stable at a countably infinite number of values of this diffusion coefficient.…”
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Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System by Ilse Bollaerts, Jessie Van houcke, Lien Andries, Lies De Groef, Lieve Moons

“…Here, we review the current knowledge on how acute inflammation is intertwined with axonal regeneration, an important component of CNS repair. …”
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Yersiniosis and acute secondary axonal sensorimotor polyneuropathy: a case report by A. Daškevičiūtė, R. Mameniškienė

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Myelin ensheathment and drug responses of oligodendrocytes are modulated by stiffness of artificial axons. by Mingyu Yang, Calliope J L Martin, Kavin Kowsari, Anna Jagielska, Krystyn J Van Vliet

“…Myelination is a key biological process wherein glial cells such as oligodendrocytes wrap myelin around neuronal axons, forming an insulative sheath that accelerates signal propagation down the axon. …”
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Live imaging of excitable axonal microdomains in ankyrin-G-GFP mice by Christian Thome, Jan Maximilian Janssen, Seda Karabulut, Claudio Acuna, Elisa D'Este, Stella J Soyka, Konrad Baum, Michael Bock, Nadja Lehmann, Johannes Roos, Nikolas A Stevens, Masashi Hasegawa, Dan A Ganea, Chloé M Benoit, Jan Gründemann, Lia Y Min, Kalynn M Bird, Christian Schultz, Vann Bennett, Paul M Jenkins, Maren Engelhardt

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Stress landscape of folding brain serves as a map for axonal pathfinding by Akbar Solhtalab, Ali H. Foroughi, Lana Pierotich, Mir Jalil Razavi

“…Simulations incorporating axon bundle reorientation and stress-induced growth reveal potential mechanical mechanisms that lead to higher axon bundle density in gyri (ridges) compared to sulci (valleys). …”
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Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer by Leopold Harnoncourt, Martin Schmoll, Christopher Festin, Laurenz Pflaum, Markus Breuss, Johanna Klepetko, Dominik C. Dotzauer, Florian J. Jaklin, Udo Maierhofer, Philipp Tratnig-Frankl, Oskar C. Aszmann, Oskar C. Aszmann

“…In these cases, supercharged end-to-side (SETS) nerve transfers preserve the continuity of the original nerves while facilitating additional axonal support to mitigate muscle atrophy. This approach enhances functional recovery and has been demonstrated to be effective in both preclinical models and clinical settings. …”
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Autophagy regulation and function in axon regeneration: new insights from Caenorhabditis elegans by Su-Hyuk Ko, Lizhen Chen

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Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient by L. M. Oliveira, R. G. Cury, L. H. Castro, R. Nitrini

“…Electrodiagnostic studies were consistent with acute motor sensory axonal neuropathy (AMSAN), and imaging showed a longitudinally extensive tumefactive contrast-enhancing hyperintense spinal cord lesion extending from T6 to the cone. …”
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Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury by Ping Li, Zhao-Qian Teng, Chang-Mei Liu

“…This article reviews the role and mechanism of differentially expressed microRNAs in regulating axon regeneration and glial scar formation after spinal cord injury, as well as their therapeutic potential for promoting axonal regeneration and repair of the injured spinal cord.…”
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Wave fronts in neuronal fields with nonlocalpost-synaptic axonal connections and delayed nonlocal feedbackconnections by Felicia Maria G. Magpantay, Xingfu Zou

“…We consider a neuronal network model with both axonal connections (in the form ofsynaptic coupling) and delayed non-local feedback connections. …”
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CRMP2 and CRMP4 Are Differentially Required for Axon Guidance and Growth in Zebrafish Retinal Neurons by Zhi-Zhi Liu, Jian Zhu, Chang-Ling Wang, Xin Wang, Ying-Ying Han, Ling-Yan Liu, Hong A. Xu

“…Axons are directed to their correct targets by guidance cues during neurodevelopment. …”
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Reactivation of Denervated Schwann Cells by Embryonic Spinal Cord Neurons to Promote Axon Regeneration and Remyelination by Xinyu Fang, Chaofan Zhang, Chongjing Zhang, Yuanqing Cai, Zibo Yu, Zida Huang, Wenbo Li, Wenming Zhang

“…In peripheral nerve injuries (PNIs) in which proximal axons do not regenerate quickly enough, significant chronic degeneration of Schwann cells (SCs) can occur at the distal stump of the injured nerve and obstruct regeneration. …”
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Gap junction intercellular communications regulates activation of SARM1 and protects against axonal degeneration by Wen Jie Zhu, Jun Liu, Wan Hua Li, Zhi Ying Zhao, Chongquan Huang, Jian Yuan Yang, Hon Cheung Lee, Yong Juan Zhao

“…Abstract Sterile alpha and Toll/interleukin-1 receptor motif containing 1 (SARM1), a nicotinamide adenine dinucleotide (NAD)-utilizing enzyme, mediates axon degeneration (AxD) in various neurodegenerative diseases. …”
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The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury by Shmma Quraishe, Lindsey H. Forbes, Melissa R. Andrews

“…After injury, however, CSPGs and tenascins contribute to the structure of the inhibitory glial scar, which actively prevents axonal regeneration. Myelin sheaths and mature adult oligodendrocytes, despite their important role in signal conduction in mature CNS axons, contribute to the inhibitory environment existing after injury. …”
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