Progressive Lower Extremity Weakness and Axonal Sensorimotor Polyneuropathy from a Mutation in KIF5A (c.611G>A;p.Arg204Gln) by Nivedita U. Jerath, Tiffany Grider, Michael E. Shy

“…Electrodiagnostic testing revealed an axonal sensorimotor polyneuropathy. Genetic testing for HSP in 2003 was negative; repeat testing in 2013 revealed a mutation in KIF5A (c.611G>A;p.Arg204Gln). …”
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Small fiber neuropathy: clinical presentation, diagnostic methods, possibly causes and treatment by E. Paulėkas, D. Garšvienė, K. Petrikonis

Subjects: “…quantitative sudomotor axon reflex test…”
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Post-injury treatment with 7,8-dihydroxyflavone attenuates white matter pathology in aged mice following focal traumatic brain injury by Georgios Michalettos, Fredrik Clausen, Elham Rostami, Niklas Marklund

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Correlation between traumatic brain injury, obesity and insulin-resistance – a case report by Laura De Wilde, Charlotte De Ruysscher, Kristine Oostra

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Diffusion Tensor Imaging as Neurologic Predictor in Patients Affected by Traumatic Brain Injury: Scoping Review by Federica Paolini, Salvatore Marrone, Gianluca Scalia, Rosa Maria Gerardi, Lapo Bonosi, Umberto Emanuele Benigno, Sofia Musso, Alba Scerrati, Domenico Gerardo Iacopino, Francesco Signorelli, Rosario Maugeri, Massimiliano Visocchi

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Presentazione by De Vido, Stefania

“…Axon…”
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Microfluidic Cultures of Basal Forebrain Cholinergic Neurons for Assessing Retrograde Cell Death by Live Imaging by Srestha Dasgupta, Mansi Pandya, Wilma Friedman

“…Neurons are highly polarized cells, with axons that may innervate distant target regions. …”
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Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View by Maria Stankiewicz, Marcin Dąbrowski, Maria Elena de Lima

“…This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap technique on isolated giant axon, patch-clamp on DUM (dorsal unpaired median) neurons, microelectrode technique in situ conditions on axon in connective and DUM neurons in ganglion, and single-fiber oil-gap technique on last abdominal ganglion synapse. …”
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Sugar Antennae for Guidance Signals: Syndecans and Glypicans Integrate Directional Cues for Navigating Neurons by Christa Rhiner, Michael O. Hengartner

“…The neurons extend thin processes, axons, that connect over wide distances with other brain cells to form a complicated neuronal network. …”
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Torsion-Induced Traumatic Optic Neuropathy (TITON): A physiologically relevant animal model of traumatic optic neuropathy. by Annie K Ryan, Brooke I Asemota, Tyler Heisler-Taylor, Claire Mello, Luis Rodriguez, William E Sponsel, Julie Racine, Tonia S Rex, Randolph D Glickman, Matthew A Reilly

“…TON is characterized by axon damage in the optic nerve followed by retinal ganglion cell death in the days and weeks following injury. …”
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Relationship between functional structures and horizontal connections in macaque inferior temporal cortex by Danling Hu, Takayuki Sato, Kathleen S. Rockland, Manabu Tanifuji, Hisashi Tanigawa

“…Using a combination of optical imaging, electrophysiological recording, and anatomical tracing, we investigated the relationship between stimulus-response maps and patterns of horizontal axon terminals in the macaque ITC. In contrast to the “like-to-like” connectivity observed in the early visual cortex, we found that horizontal axons in ITC do not preferentially connect sites with similar object selectivity. …”
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Research Progress on Biomaterials for Spinal Cord Repair by Liao Z, Bao Q, Saijilahu, Chimedtseren C, Tumurbaatar K, Saijilafu

“…In addition, the glial scars and inflammatory responses around the lesion site are another major obstacle for successful axon regeneration after SCI. However, biomaterials are highly biocompatible, and they could provide physical guidance to allow regenerating axon growth over the lesion site and restore functional neural circuits. …”
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Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons by Eun-Hae Jang, Aeri Sim, Sun-Kyoung Im, Eun-Mi Hur

“…Several studies have demonstrated the therapeutic potential of applying microtubule- (MT-) stabilizing agents (MSAs) that cross the blood-brain barrier to promote axon regeneration and prevent axonal dystrophy in rodent models of spinal cord injury and neurodegenerative diseases. …”
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Physiological Properties of Supragranular Cortical Inhibitory Interneurons Expressing Retrograde Persistent Firing by Barbara Imbrosci, Angela Neitz, Thomas Mittmann

“…Despite this well accepted notion, recent research has shown that, under certain circumstances, the axon can also generate APs independent of synaptic inputs at axonal sites distal from the soma. …”
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Peripheral Nerve Regeneration with Acellular Nerve Allografts Seeded with Amniotic Fluid-Derived Stem Cells by Xue Ma, Eileen Elsner, Jiaozhong Cai, Thomas L. Smith, Zhongyu Li

“…Tissue engineering strategies have attempted to mimic regenerating axons’ environment by adding supportive types of cells other than Schwann cell to the nerve allograft. …”
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Reduced Fascicle Area Demonstrated in Ilioinguinal Nerves Resected from Primary Inguinal Herniorrhaphy Patients as Evidence of Compression Neuropathy by Robert Wright, Donald E. Born, Troy Sanders, Jordan Landes, Troy Salisbury, Anjali S. Kumar, Makena Horne

“…Further studies with larger samples are needed to confirm the observed effect of nerve location on the total nerve cross-sectional area and axon loss.…”
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Biomaterial-based strategies: a new era in spinal cord injury treatment by Shihong Zhu, Sijun Diao, Xiaoyin Liu, Zhujun Zhang, Fujun Liu, Wei Chen, Xiyue Lu, Huiyang Luo, Xu Cheng, Qiang Liao, Zhongyu Li, Jing Chen

“…Additionally, these scaffolds should facilitate axon growth and neurogenesis by offering adjustable topography and a range of physical and biochemical cues. …”
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Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells by Sasi Kumar Jagadeesan, Ahmad Galuta, Ryan Vimukthi Sandarage, Eve Chung Tsai

“…Enrichment of pathways related to neurogenesis, axon guidance, and synaptic signaling varied across donors, highlighting the impact of genetic and epigenetic individuality on NSPC behavior.…”
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Neuroprotective and Neurorestorative Processes after Spinal Cord Injury: The Case of the Bulbospinal Respiratory Neurons by Anne Kastner, Valéry Matarazzo

“…Since part of this recovery is dependent on the damaged side of the spinal cord, the present review highlights our current understanding of the anatomical neuroplasticity processes that are developed by the surviving damaged bulbospinal neurons, notably axonal sprouting and rerouting. Such anatomical neuroplasticity relies also on coordinated molecular mechanisms at the level of the axotomized bulbospinal neurons that will promote both neuroprotection and axon growth.…”
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