Low-Dose Taxol Promotes Neuronal Axons Extension and Functional Recovery after Spinal Cord Injury by Baoguo Liu, Sumei Liu, Dejun Sun

“…Axonal regeneration has been the research focus in the field of clinical treatment for spinal cord injury (SCI). …”
Get full text

AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury by Wen-Yuan Li, Ying Wang, Feng-Guo Zhai, Ping Sun, Yong-Xia Cheng, Ling-Xiao Deng, Zhen-Yu Wang

“…DPSN axons mediate and maintain a variety of normal spinal functions. …”
Get full text

GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand by Tomoaki Suzuki, Ken Kadoya, Takeshi Endo, Miwako Yamasaki, Masahiko Watanabe, Norimasa Iwasaki

Subjects: “…axon regeneration…”
Get full text

Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

Get full text

CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation by Minghui Tan, Caihui Cha, Yongheng Ye, Jifeng Zhang, Sumei Li, Fengming Wu, Sitang Gong, Guoqing Guo

“…CRMP2 and CRMP4 also interacted with one another coordinately to promote growth cone development and axonal elongation. Genetic silencing of CRMP2 enhanced, whereas overexpression of CRMP2 suppressed, the inhibitory effects of CRMP4 knockdown on axonal development. …”
Get full text

GPX modulation promotes regenerative axonal fusion and functional recovery after injury through PSR-1 condensation by Su-Hyuk Ko, Kyung-Ah Cho, Xin Li, Qitao Ran, Zhijie Liu, Lizhen Chen

“…Abstract Axonal fusion represents an efficient way to recover function after nerve injury. …”
Get full text

Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats by Yonglin Zhao, Yahui Zhao, Ming Zhang, Junjie Zhao, Xudong Ma, Tingqin Huang, Honggang Pang, Jiaxi Li, Jinning Song

“…Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. …”
Get full text

Involvement of Toll Like Receptor 2 Signaling in Secondary Injury during Experimental Diffuse Axonal Injury in Rats by Yonglin Zhao, Junjie Zhao, Ming Zhang, Yahui Zhao, Jiaxi Li, Xudong Ma, Tingqin Huang, Honggang Pang, Bo Wang, Jinning Song

“…Treatment of diffuse axonal injury (DAI) remains challenging in clinical practice due to the unclear pathophysiological mechanism. …”
Get full text

A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient by Uchechukwu Ibewuike, MBBS, John Kim, MD, Swati Mody, MBBS, Gregory Obala, MD, Ebere Ibezim, MBBS

Subjects: “…Acute motor axonal neuropathy…”
Get full text

Following Spinal Cord Injury Transected Reticulospinal Tract Axons Develop New Collateral Inputs to Spinal Interneurons in Parallel with Locomotor Recovery by Zacnicte May, Keith K. Fenrich, Julia Dahlby, Nicholas J. Batty, Abel Torres-Espín, Karim Fouad

“…The RtST drives the initiation of locomotion and postural control. RtST axons form new contacts with propriospinal interneurons (PrINs) after incomplete spinal cord injury (SCI); however, it is unclear if injured or uninjured axons make these connections. …”
Get full text

Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats by J. Bryan Iorgulescu, Samik P. Patel, Jack Louro, Christian M. Andrade, Andre R. Sanchez, Damien D. Pearse

“…Although SC implants provide a receptive environment for axonal regrowth and support functional recovery in a number of experimental SCI models, axonal regeneration is largely limited to local systems and the behavioral improvements are modest without additional combinatory approaches. …”
Get full text

Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity by Yang Wang, Jianguo Xu, Wanchun You, Haitao Shen, Xiang Li, Zhengquan Yu, Haiying Li, Gang Chen

Subjects: Get full text

Synapse Plasticity in Motor, Sensory, and Limbo-Prefrontal Cortex Areas as Measured by Degrading Axon Terminals in an Environment Model of Gerbils (Meriones unguiculatus) by Janina Neufeld, Gertraud Teuchert-Noodt, Keren Grafen, York Winter, A. Veronica Witte

“…We therefore investigated (pre)synaptic plasticity in various cortices of adult rodents, visualized by secondary lysosome accumulations (LA) in remodeling axon terminals. Twenty-two male gerbils from either enriched (ER) or impoverished rearing (IR) were used for quantification of silver-stained LA. …”
Get full text

Muscarinic acetylcholine type 1 receptor antagonism activates TRPM3 to augment mitochondrial function and drive axonal repair in adult sensory neurons by Sanjana Chauhan, Darrell R. Smith, Shiva Shariati-Ievari, Abhay Srivastava, Sanjiv Dhingra, Michel Aliani, Paul Fernyhough

Subjects: “…Axonal regeneration…”
Get full text

A Case of Acute Motor Sensory Axonal Neuropathy: A Variant of Guillain-Barré Syndrome, with Possible Syndrome of Irreversible Lithium-Effectuated Neurotoxicity by David Y. Liu, Jessica R. Hollenbach, Jason A. Gregorin, Jonathan H. Wynbrandt

“…Acute Motor Sensory Axonal Neuropathy (AMSAN) is a rare and severe variant of Guillain-Barré syndrome (GBS) that has a prolonged recovery course. …”
Get full text

Fetal Spinal Cord Tissue in Mini-Guidance Channels Promotes Longitudinal Axonal Growth after Grafting into Hemisected Adult Rat Spinal Cords by Norman I. Bamber, Huaying Li, Patrick Aebischer, Xiao Ming Xu

“…Solid fetal spinal cord (FSC) tissue, seeded into semipermeable mini-guidance channels, was tested for the ability to promote axonal growth across the gap created by a midthoracic (T8) hemisection in adult rats. …”
Get full text

Correction to: Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity by Yang Wang, Jianguo Xu, Wanchun You, Haitao Shen, Xiang Li, Zhengquan Yu, Haiying Li, Gang Chen

Get full text

The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression by Callan L. Attwell, Inés Maldonado-Lasunción, Ruben Eggers, Bastiaan A. Bijleveld, Ward M. Ellenbroek, Natascha Siersema, Lotte Razenberg, Dédé Lamme, Nitish D. Fagoe, Ronald E. van Kesteren, August B. Smit, Joost Verhaagen, Matthew R. J. Mason

Subjects: “…Axon regeneration…”
Get full text

The role of neurofilament light chain in the context of neurological disorders by V. Taluntienė, R. Motiekaitytė, R. Kizlaitienė, N. Giedraitienė, G. Kaubrys

Subjects: Get full text

Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not sorted into axons by Sofia Lyng Wæver, Kristian Agmund Haanes

“…Results The IHC showed that the key isoform localized within the axons of the mouse TG neurons, is αCGRP and not βCGRP. …”
Get full text