Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis by Mario Enrique Baltazares-Lipp, Juan Ignacio Soto-González, Carlos Manuel Aboitiz-Rivera, Héctor A. Carmona-Ruíz, Benito Sarabia Ortega, Ruben Blachman-Braun

“…Despite treatment, the patient deceased seven days after admission. Autopsy confirmed the diagnosis of Löffler endocarditis.…”
Get full text

Aspergillus Thyroiditis: A Complication of Respiratory Tract Infection in an Immunocompromised Patient by Madiha M. Alvi, David S. Meyer, Nicholas J. Hardin, James G. deKay, Annis M. Marney, Matthew P. Gilbert

“…The patient’s condition deteriorated rapidly over his brief hospital course and he expired. Autopsy showed fungal thyroiditis secondary to disseminated invasive Aspergillus. …”
Get full text

A Case of Waterhouse-Friderichsen Syndrome Resulting from an Invasive Pneumococcal Infection in a Patient with a Hypoplastic Spleen by Kazumasa Emori, Nobuhiro Takeuchi, Junichi Soneda

“…The following day, blood cultures revealed the presence of Streptococcus pneumoniae. An autopsy revealed a hypoplastic spleen and a bilateral adrenal hemorrhage, indicating acute adrenal insufficiency caused by sepsis. …”
Get full text

A Case of Disseminated Cryptococcal Infection and Concurrent Lung Tuberculosis in a Patient under Steroid Therapy for Interstitial Pneumonia by Aoi Kuroda, Sadatomo Tasaka, Kazuma Yagi, Takao Mochimaru, Tetsuo Tani, Ho Namkoong, Kyuto Tanaka, Yusuke Suzuki, Mami Hatano, Naoki Hasegawa, Yasunori Okada, Tomoko Betsuyaku

“…Based on the patient’s clinical course, serial computed tomography images, and autopsy results, we believe that the preceding several months of corticosteroid treatment might have contributed to these coinfections in the lungs already vulnerable due to underlying fibrosis.…”
Get full text

Features of diagnosis and treatment of gastrointestinal stromal tumors by N. I. Bogomolov, T. V. Burdinskaya, M. A. Goncharova, A. G. Goncharov, N. N. Tomskikh

“…In the remote period after surgery one patient died due to tumor metastasis, in 7 patients GIST was primarily diagnosed at the autopsy. Targeted therapy by tyrosine kinase inhibitors was carried out for 14 patients. …”
Get full text

Fatal Multiorgan Failure Associated with Disseminated Herpes Simplex Virus-1 Infection: A Case Report by Michael Glas, Sigrun Smola, Thorsten Pfuhl, Juliane Pokorny, Rainer M. Bohle, Arno Bücker, Jörn Kamradt, Thomas Volk

“…Post-mortem polymerase chain reaction analyses confirmed a disseminated infection with HSV-1 involving various organs and tissues but excluding the central nervous system. Autopsy revealed a predominantly retroperitoneal diffuse large B-cell lymphoma as the suspected origin of immunosuppression underlying herpes simplex dissemination.…”
Get full text

Maternal Hypertension and Early Atherosclerotic Lesions in Aortas of Deceased Fetuses and Neonates by Janet María Capote-Santa Cruz Pacheco, Carmen Teresa Peraza Méndez, Marlene Ferrer Arrocha, Lisandra Álvarez de la Nuez, Belkis Ortega de la Campa, Mirian Castro Ortega

“…<br /><strong>Method:</strong> a descriptive cross-sectional study was carried out that included fetuses older than 22 weeks and deceased neonates born to hypertensive mothers, who underwent autopsy in the pathological anatomy department of the Eusebio Hernández Pérez Gynecobstetric University Hospital, in the period between January 2021 and December 2022, with a total of 18. …”
Get full text

Congenital Chylothorax: Case Report by Egemen Tolunay, Bulut Varlı, Fırat Tülek, Emre Pabuçcu, Şerife Esra Çetinkaya, Korhan Kahraman, Acar Koç

“…Rarely, congenital malformations of the thoracic duct and variational changes of embryonic lymphatic network were reported after autopsy. Some cases of chylothorax are found to be associated with Turner, Down and Noonan syndromes. …”
Get full text

Systemic Lupus Erythematosus (SLE) with Acute Nephritis, Antineutrophil Cytoplasmic Antibody- (ANCA-) Associated Vasculitis, and Thrombotic Thrombocytopenic Purpura (TTP): A Rare C... by Sohail Farshad, Christopher Kanaan, Solomiia Savedchuk, Dillon S. Karmo, Alexandra Halalau, Abhishek Swami

“…Laboratory tests later showed ADAMTS13 activity less than 10% consistent with TTP and p-antineutrophil cytoplasmic antibody (ANCA) positivity. Autopsy revealed small-vessel vasculitis of the visceral organs. …”
Get full text

Spontaneous Complete Regression of Colon Cancer Liver Metastases in a Lung Transplant Patient: A Case Report by Koen Zwart, Dieuwertje Ruigrok, Magda de Graaf-Bos, Roel Goldschmeding, Miriam Koopman, Guus M. Bol

“…Unfortunately, the patient developed rejection of her lung transplant and succumbed to pulmonary disease six months following her cancer diagnosis. The autopsy confirmed the primary colon tumor location and complete regression of >40 liver metastases. …”
Get full text

Pedunculated Cecal Lipoma Causing Colo-Colonic Intussusception: A Rare Case Report by Stefanos Atmatzidis, Grigoris Chatzimavroudis, Aristidis Patsas, Basilis Papaziogas, Spiros Kapoulas, Stelios Kalaitzis, Ananias Ananiadis, John Makris, Konstantinos Atmatzidis

“…Colonic lipomas are uncommon nonepithelial neoplasms that are typically sessile, asymptomatic and incidentally found during endoscopy, surgery, or autopsy. We present a very rare case of a 34-year-old female patient with symptomatic pedunculated cecal lipoma causing intermittent colo-colonic intussusception. …”
Get full text

INFLUENCE OF EXO- AND ENDOGENOUS FACTORS ON THE MORPHOLOGICAL AND FUNCTIONAL STATE OF THE SPLEEN AS AN IMPORTANT MEDICAL AND SOCIAL PROBLEM OF THE HEALTH CARE SYSTEM by O.V. Mamai, S.M. Bilash, R.M. Grinko

“…Changes in the spleen are also known to occur in the setting of death from anaphylaxis, drowning, and sepsis. Autopsy of the spleen plays an important role in toxicological research. …”
Get full text

Diaphragmatic Amyloidosis Causing Respiratory Failure: A Case Report and Review of Literature by Aleksey Novikov, Horatio Holzer, Robert A. DeSimone, Ghaith Abu-Zeinah, David J. Pisapia, Tomer M. Mark, Raymond D. Pastore

“…Despite treatment attempts, the patient passed away in the intensive care unit from hypercapnic respiratory failure. Autopsy revealed dense diaphragmatic amyloid deposits without phrenic nerve infiltration or demyelination or lung parenchymal involvement. …”
Get full text

Mediators of monocyte chemotaxis and matrix remodeling are associated with mortality and pulmonary fibroproliferation in patients with severe COVID-19. by Sarah E Holton, Mallorie Mitchem, Hamid Chalian, Sudhakar Pipavath, Eric D Morrell, Pavan K Bhatraju, Jessica A Hamerman, Cate Speake, Uma Malhotra, Mark M Wurfel, Steven E Ziegler, Carmen Mikacenic

“…Pulmonary fibrosis following COVID-19 pneumonia has been described at autopsy and following lung transplantation. We hypothesized that protein mediators of tissue remodeling and monocyte chemotaxis are elevated in the plasma and endotracheal aspirates of critically ill patients with COVID-19 who subsequently develop features of pulmonary fibroproliferation. …”
Get full text

TDP-43 as a potential retinal biomarker for neurodegenerative diseases by Margit Glashutter, Margit Glashutter, Printha Wijesinghe, Joanne A. Matsubara, Joanne A. Matsubara

“…A major limitation of human autopsy studies is the lack of corresponding brain pathology assessments to confirm TDP-43 proteinopathy diagnosis and staging. …”
Get full text

Immunohistochemistry for (Pro)renin Receptor in Humans by Satoshi Morimoto, Noriko Morishima, Daisuke Watanabe, Yoichiro Kato, Noriyuki Shibata, Atsuhiro Ichihara

“…Systemic immunohistochemical examination of (pro)renin receptor expression was performed in whole body organs of autopsy cases. (Pro)renin receptor immunostaining was observed in the cytoplasm of cells in almost all human organs. …”
Get full text

Doble mecanismo de sofocación homicida. A propósito de un caso by Yaima González Cabrera, Yunier Riverol González, Dayami Llanes Pulido

“…According to police data, it was learned that her husband left the house, returning 24 hours later, realizing that she was tied by the neck to a rope that was hanging from a beam on the ceiling, and a cloth was inserted into her mouth. she. During the autopsy, hemorrhagic infiltrates were found in the skull, neck, and bilateral supraclavicular region; the hyoid bone was fractured in the greater horn and an ecchymosis at the base of the tongue. …”
Get full text

Inverse Relationship Between Leydig Cell Density and Metastatic Potential of Prostatic Adenocarcinoma by W. John Wang, Y. Albert Yeh, Paul Stout, Kang Fan

“…Thirty‐eight age‐compatible autopsy cases who died of unrelated causes served as normal controls. …”
Get full text

Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death by Jialin Dai, Jiangjin Liu, Qiong Zhang, Yang An, Bing Xia, Changwu Wan, Yuanyuan Zhang, Yanni Yu, Jie Wang

“…It provides a proteomic analysis of human left anterior descending coronary artery from subjects diagnosed with SCD through histological examination and cases of nondisease accidental deaths through autopsy. A total of 2784 proteins were obtained from label-free quantitative proteomic analysis. …”
Get full text

A Gastrointestinal Stromal Tumor of the Stomach Demonstrating a Stepwise Progression from Low- to High-Grade Malignancy by Takahiko Nakajima, Tomonori Ushijima, Atsushi Kihara, Kenichiro Murata, Toshiro Sugiyama, Koichi Tsuneyama, Johji Imura, Junichi Fukushima, Hajime Horiuchi

“…The patient followed an unfavorable clinical course and died of liver dysfunction 55 months after surgery. Autopsy was performed. By comparing the immunohistochemical profiles of primary and metastatic tumors, it was established that only the tumor cells with highly aggressive characteristics had metastasized.…”
Get full text