Autophagy in Inflammatory Diseases by Alexander J. S. Choi, Stefan W. Ryter

“…Autophagy provides a mechanism for the turnover of cellular organelles and proteins through a lysosome-dependent degradation pathway. …”
Get full text

Selective Autophagy in Drosophila by Ioannis P. Nezis

“…Autophagy is an evolutionarily conserved process of cellular self-eating and is a major pathway for degradation of cytoplasmic material by the lysosomal machinery. …”
Get full text

Autophagy inhibitor 3-methyladenine mitigates the severity of colitis in aged mice by inhibiting autophagy by Ailing Liu, Hongying Wang, Hong Lv, Hong Yang, Yue Li, Jiaming Qian

Subjects: “…Cell autophagy…”
Get full text

Receptor Proteins in Selective Autophagy by Christian Behrends, Simone Fulda

“…Autophagy has long been thought to be an essential but unselective bulk degradation pathway. …”
Get full text

Histone demethylases in autophagy and inflammation by Yaoyao Ma, Wenting Lv, Yi Guo, Tong Yin, Yujie Bai, Ziqi Liu, Chao Chen, WenjuanYang, Jiayi Feng, Wenbin Qian, Ruiling Tang, Yanting Su, Shigang Shan, Huifen Dong, Yongfen Bao, Lihua Qu

Subjects: Get full text

Zymophagy: Selective Autophagy of Secretory Granules by Maria I. Vaccaro

“…In this work, we revise the molecules and mechanisms that mediate zymophagy, a selective autophagy of secretory granules.…”
Get full text

The Impact of Autophagy on Cell Death Modalities by Stefan W. Ryter, Kenji Mizumura, Augustine M. K. Choi

“…Autophagy represents a homeostatic cellular mechanism for the turnover of organelles and proteins, through a lysosome-dependent degradation pathway. …”
Get full text

The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy by Kosuke Yamahara, Mako Yasuda, Shinji Kume, Daisuke Koya, Hiroshi Maegawa, Takashi Uzu

“…Autophagy activity is regulated by both nutrient state and intracellular stresses. …”
Get full text

Lipophagy: Connecting Autophagy and Lipid Metabolism by Rajat Singh, Ana Maria Cuervo

“…This paper focuses on the characteristics of this new type of selective autophagy and the cellular consequences of the mobilization of intracellular lipids through this process. …”
Get full text

Autophagy in Immune-Related Renal Disease by Xin Ye, Xu-jie Zhou, Hong Zhang

“…Autophagy is an important biology process, central to the maintenance of biology process in both physiological and pathological situations. …”
Get full text

Impaired Autophagy of GABAergic Interneurons in Neuropathic Pain by Yuhua Yin, Min-Hee Yi, Dong Woon Kim

“…These impairments in GABAergic interneurons may be associated with dysfunctional autophagy, resulting in neuropathic pain. Here, we review an emerging number of investigations that suggest a pivotal role of impaired autophagy of GABAergic interneurons in NP. …”
Get full text

Canonical and noncanonical autophagy: involvement in Parkinson’s disease by Maria Sakurai, Tomoki Kuwahara

Subjects: “…noncanonical autophagy…”
Get full text

Autophagy-lysosome pathway in insulin & glucagon homeostasis by Yi Wu, Yi Wu, Yi Wu, Hui Wang, Huoyan Xu

Subjects: Get full text

Autophagy in Macrophages: Impacting Inflammation and Bacterial Infection by Ali Vural, John H. Kehrl

“…Innate immune responses include the rapid induction of transcriptional networks that trigger the production of cytokines, chemokines, and cytotoxic molecules; the mobilization of cells including neutrophils and other leukocytes; the engulfment of pathogens by phagocytosis and their delivery to lysosome for degradation; and the induction of autophagy. Autophagy is a catabolic process that normally maintains cellular homeostasis in a lysosome-dependent manner, but it also functions as a cytoprotective response that intersects with a variety of general stress-response pathways. …”
Get full text

Aging, cancer, and autophagy: connections and therapeutic perspectives by Begoña Zapatería, Esperanza Arias, Esperanza Arias

“…The interplay between aging, cancer, and autophagy reveals key insights into tumorigenesis, cellular senescence, and proteostasis dysfunction. …”
Get full text

The regulatory role of cystatin C in autophagy and neurodegeneration by T. A. Korolenko, A. B. Shintyapina, A. B. Pupyshev, A. A. Akopyan, G. S. Russkikh, M. A. Dikovskaya, V. A. Vavilin, E. L Zavjalov, M. A. Tikhonova, T. G. Amstislavskaya

Subjects: Get full text

Autophagy: More Than a Nonselective Pathway by Fulvio Reggiori, Masaaki Komatsu, Kim Finley, Anne Simonsen

“…The key actors mediating the biogenesis of these carriers are the autophagy-related genes (ATGs). For a long time, it was assumed that autophagy is a bulk process. …”
Get full text

Correction: In search of autophagy biomarkers in breast cancer: Receptor status and drug agnostic transcriptional changes during autophagy flux in cell lines. by PLOS ONE Staff

Get full text

Host Cell Autophagy in Immune Response to Zoonotic Infections by Panagiotis Skendros, Ioannis Mitroulis

“…Autophagy is a fundamental homeostatic process in which cytoplasmic targets are sequestered within double-membraned autophagosomes and subsequently delivered to lysosomes for degradation. …”
Get full text

Inducers of Autophagy and Cell Death: Focus on Copper Metabolism by Weikang Ling, Shuo Li, Yang Zhu, Xin Wang, Dongmei Jiang, Bo Kang

Subjects: Get full text