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Mechanisms of Copper-Induced Autophagy and Links with Human Diseases
Published 2025-01-01Subjects: “…autophagy…”
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22
Liposomal Formulation of Hydroxychloroquine Can Inhibit Autophagy In Vivo
Published 2024-12-01Subjects: Get full text
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23
GDF11 restores the impaired function of EPCs-MA by promoting autophagy: GDF11 ameliorates endothelial progenitor cell aging by promoting autophagy
Published 2025-01-01Subjects: Get full text
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24
Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival
Published 2012-01-01“…Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of autophagy. These selective forms of autophagy, including mitophagy, nucleophagy, and ubiquitin-mediated autophagy, counteract apoptotic signals by removing damaged cellular structures and by reprogramming cellular energy metabolism to cope with therapeutic stress. …”
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25
The Role of Autophagy and Related MicroRNAs in Inflammatory Bowel Disease
Published 2018-01-01“…Related studies have shown that miR-142-3p, miR-320, miR-192, and miR-122 target NOD2, an IBD-relevant autophagy gene, to modulate autophagy in IBD. miR-142-3p, miR-93, miR-106B, miR-30C, miR-130a, miR-346, and miR-20a regulate autophagy by targeting ATG16L1 through several different pathways. miR-196 can downregulate IRGM and suppress autophagy by inhibiting the accumulation of LC3II. …”
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26
Arabidopsis multiomics reveals the role of autophagy in root microbiome assembly
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27
Autophagy-associated signal pathways of functional foods for chronic diseases
Published 2019-03-01“…Keywords: Autophagy, Chronic diseases, Resveratrol, Epigallocatechin-3-gallate, Curcumin, Trehalose…”
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28
Autophagy in brain tumors: molecular mechanisms, challenges, and therapeutic opportunities
Published 2025-01-01Subjects: “…Autophagy…”
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29
Three-Axis Model for Atg Recruitment in Autophagy against Salmonella
Published 2012-01-01“…In this paper, we will discuss how the autophagy machinery is recruited in proximity to Salmonella. …”
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30
Diversity in the Regulation of Autophagy and Mitophagy: Lessons from Parkinson's Disease
Published 2011-01-01“…Selective mitochondrial degradation through autophagy (mitophagy) has emerged as an important homeostatic mechanism in a variety of organisms and contexts. …”
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31
Oxidative Stress and Autophagy: Unraveling the Hidden Threat to Boars’ Fertility
Published 2024-12-01Subjects: Get full text
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32
Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
Published 2010-01-01“…The UPR is tailored essentially to reestablish ER homeostasis also through adaptive mechanisms involving the stimulation of autophagy. However, when persistent, ER stress can switch the cytoprotective functions of UPR and autophagy into cell death promoting mechanisms. …”
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33
Plants and fungi metabolites as novel autophagy inducers and senescence inhibitors
Published 2024-07-01Subjects: “…autophagy…”
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34
Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction
Published 2020-01-01“…Understanding the multifactorial changes involved in the kidney and heart after acute myocardial infarction (AMI) is prerequisite for further mechanisms and early intervention, especially autophagy changes. Here, we discussed the role of adaptive autophagy in the heart and kidney of rats with AMI. …”
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Investigation of the Effect of Astaxanthin on Autophagy in Renal Ischemia-reperfusion Modeled Rats
Published 2024-06-01Subjects: Get full text
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36
Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection.
Published 2025-01-01“…Autophagy plays a crucial role in the host response to Mycobacterium tuberculosis (Mtb) infection, yet the dynamics and regulation of autophagy induction on Mtb-containing vacuoles (MCVs) remain only partially understood. …”
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Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change
Published 2024-01-01“…Autophagy starts from the moment of induction during the formation of a phagophore. …”
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38
A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease
Published 2012-01-01“…Apart from cytotoxicity, changes in autophagy have been consistently reported in the context of G2019S mutant LRRK2. …”
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Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy
Published 2013-01-01“…In autophagy deficient (ATG5−/−) mouse embryonic fibroblasts, or in normal cells treated with the autophagy-inhibitor 3-MA, Mut-PrP colocalization with lysosomes was reduced to a similar extent. …”
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Autophagy Mediates MMP-2 Expression in Glaucomatous Trabecular Meshwork Cells
Published 2022-01-01“…Cellular mRNA and protein were measured at different 3-MA concentrations and starvation time periods. The level of autophagy was accessed by monodansylcadaverine fluorescent staining and expression of specific autophagy-related genes, light chain 3 (LC3), and Beclin1. …”
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