Showing 21 - 40 results of 535 for search '"autophagy"', query time: 0.07s Refine Results
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    Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival by Luke R. K. Hughson, Vincent I. Poon, Jaeline E. Spowart, Julian J. Lum

    Published 2012-01-01
    “…Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of autophagy. These selective forms of autophagy, including mitophagy, nucleophagy, and ubiquitin-mediated autophagy, counteract apoptotic signals by removing damaged cellular structures and by reprogramming cellular energy metabolism to cope with therapeutic stress. …”
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    Article
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    The Role of Autophagy and Related MicroRNAs in Inflammatory Bowel Disease by Shiyuan Wang, Yan Huang, Cili Zhou, Huangan Wu, Jimeng Zhao, Luyi Wu, Min Zhao, Fang Zhang, Huirong Liu

    Published 2018-01-01
    “…Related studies have shown that miR-142-3p, miR-320, miR-192, and miR-122 target NOD2, an IBD-relevant autophagy gene, to modulate autophagy in IBD. miR-142-3p, miR-93, miR-106B, miR-30C, miR-130a, miR-346, and miR-20a regulate autophagy by targeting ATG16L1 through several different pathways. miR-196 can downregulate IRGM and suppress autophagy by inhibiting the accumulation of LC3II. …”
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    Autophagy-associated signal pathways of functional foods for chronic diseases by Jinfeng Xie, Jiling Liang, Ning Chen

    Published 2019-03-01
    “…Keywords: Autophagy, Chronic diseases, Resveratrol, Epigallocatechin-3-gallate, Curcumin, Trehalose…”
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    Article
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    Three-Axis Model for Atg Recruitment in Autophagy against Salmonella by Takeshi Noda, Shun Kageyama, Naonobu Fujita, Tamotsu Yoshimori

    Published 2012-01-01
    “…In this paper, we will discuss how the autophagy machinery is recruited in proximity to Salmonella. …”
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    Diversity in the Regulation of Autophagy and Mitophagy: Lessons from Parkinson's Disease by Charleen T. Chu

    Published 2011-01-01
    “…Selective mitochondrial degradation through autophagy (mitophagy) has emerged as an important homeostatic mechanism in a variety of organisms and contexts. …”
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    Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy by Tom Verfaillie, Maria Salazar, Guillermo Velasco, Patrizia Agostinis

    Published 2010-01-01
    “…The UPR is tailored essentially to reestablish ER homeostasis also through adaptive mechanisms involving the stimulation of autophagy. However, when persistent, ER stress can switch the cytoprotective functions of UPR and autophagy into cell death promoting mechanisms. …”
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    Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction by Zhendong Feng, Han Xue Jiang, Huiyang Chen, Yu Ning Liu, Yahui Wang, Rui Bing Yang, Xueting Han, Chen Hui Xia, Ze Bing Zhu, Hongcai Shang, Aiming Wu, Wei Jing Liu

    Published 2020-01-01
    “…Understanding the multifactorial changes involved in the kidney and heart after acute myocardial infarction (AMI) is prerequisite for further mechanisms and early intervention, especially autophagy changes. Here, we discussed the role of adaptive autophagy in the heart and kidney of rats with AMI. …”
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    Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection. by Jacques Augenstreich, Anna T Phan, Charles N S Allen, Anushka Poddar, Hanzhang Chen, Lalitha Srinivasan, Volker Briken

    Published 2025-01-01
    “…Autophagy plays a crucial role in the host response to Mycobacterium tuberculosis (Mtb) infection, yet the dynamics and regulation of autophagy induction on Mtb-containing vacuoles (MCVs) remain only partially understood. …”
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    A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease by Patricia Gómez-Suaga, Elena Fdez, Marian Blanca Ramírez, Sabine Hilfiker

    Published 2012-01-01
    “…Apart from cytotoxicity, changes in autophagy have been consistently reported in the context of G2019S mutant LRRK2. …”
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    Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy by Constanza J. Cortes, Kefeng Qin, Eric M. Norstrom, William N. Green, Vytautas P. Bindokas, James A. Mastrianni

    Published 2013-01-01
    “…In autophagy deficient (ATG5−/−) mouse embryonic fibroblasts, or in normal cells treated with the autophagy-inhibitor 3-MA, Mut-PrP colocalization with lysosomes was reduced to a similar extent. …”
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    Autophagy Mediates MMP-2 Expression in Glaucomatous Trabecular Meshwork Cells by Yan-Ling Xiao, Xiao-Rui Wang, Kejing Ye, Wan-Zhu Chen, Bing-Ru Zheng, Yi-Hong Huang, Yu-Yu Wu

    Published 2022-01-01
    “…Cellular mRNA and protein were measured at different 3-MA concentrations and starvation time periods. The level of autophagy was accessed by monodansylcadaverine fluorescent staining and expression of specific autophagy-related genes, light chain 3 (LC3), and Beclin1. …”
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