Showing 201 - 220 results of 535 for search '"autophagy"', query time: 0.06s Refine Results
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    Ginkgolide B Protects Cardiomyocytes from Angiotensin II-Induced Hypertrophy via Regulation of Autophagy through SIRT1-FoxO1 by Qingyuan Jiang, Ming Lu, Jinyu Li, Zhongsheng Zhu

    Published 2021-01-01
    “…GB further increased Ang II-induced autophagy in H9c2 cells and modulated expressions of autophagy-related proteins Beclin1 and P62. …”
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    ROS-ERK Pathway as Dual Mediators of Cellular Injury and Autophagy-Associated Adaptive Response in Urinary Protein-Irritated Renal Tubular Epithelial Cells by Jian-kun Deng, Xueqin Zhang, Hong-luan Wu, Yu Gan, Ling Ye, Huijuan Zheng, Zebing Zhu, Wei Jing Liu, Hua-feng Liu

    Published 2021-01-01
    “…Interestingly, we also found that the increased expression of microtubule-associated protein 1 light chain 3 (LC3)-II (a key marker of autophagy) and the decreased expression of p62 (autophagic substrate) induced by urinary proteins were reversed by U0126, suggesting autophagy was activated by ERK pathway. …”
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  5. 205

    Staphylococcus aureus blocks host autophagy through circSyk/miR-5106/Sik3 axis to promote progression of bone infection. by Zhihao Chen, Qiyuan Jin, Jinqi Zhong, Zonggang Xie, Qi Chen, Liubing Li, Jijie Li, Chenhao Zhao, Junfeng Wang, Xiaoying Tang, Mingxiao Han, Ru Li, Ziyuan Li, Zelei Tong, Min Wang, Hong Du, Haifang Zhang

    Published 2025-01-01
    “…Bone infections are mainly caused by S. aureus and require extensive surgical intervention and long-term antibiotic therapy. The host autophagy response is critical to the elimination of S. aureus infections. …”
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    UBE2T/CDC42/CD276 signaling axis mediates brain metastasis of triple-negative breast cancer via lysosomal autophagy by Lin Li, Rong Fu, Yan Chen, Jin Yao, Xiaobing Jiang, Tao Liang, Jun jun Li, Qian zhi Chen, Liang Liang Shi, Ming Xing Xie, Xin Wei Qiao, Qi Hong Cheng, Min Jie Wang

    Published 2025-02-01
    “…Mechanistically, UBE2T directly interacts with CDC42, promoting its K48-linked polyubiquitination and proteasomal degradation, thereby inhibiting CDC42 from degrading CD276 via the autophagy-lysosomal pathway, indirectly upregulating CD276 and thereby impairing the CD8+ T cells function, ultimately mediating tumor immune escape and BrM. …”
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    Hydroxychloroquine Potentiates Apoptosis Induced by PPARα Antagonist in 786-O Clear Cell Renal Cell Carcinoma Cells Associated with Inhibiting Autophagy by Ruizhe Mao, Jian Shi, Xuyi Ma, Haiyan Xu

    Published 2021-01-01
    “…The findings also revealed that the PPARα antagonist GW6471 can lower cell viability and induce autophagy in the 786-O ccRCC cell line. This autophagy can be inhibited by hydroxychloroquine. …”
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