Incidence rate and associated patient characteristics of liver disease in Wales 2004–2022: a retrospective population-scale observational study by Ashley Akbari, Andrew Yeoman, Haroon Ahmed, Jingwei Gao, Aled Davies, Thomas Peter Ignatius Pembroke

“…A total of 79 992 individuals (72%) entered the cohort with the underlying aetiology of liver disease, including alcohol-related liver disease, non-alcoholic fatty liver disease (NAFLD), viral hepatitis, metabolic, haemochromatosis and autoimmune liver diseases. NAFLD has contributed to most of the change in incidence.Conclusions We observed increasing incidence rates of liver disease in Wales, with NAFLD showing a particularly sharp increase and frequently identified as an underlying condition. …”
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Possible Implication of Local Immune Response in Darier's Disease: An Immunohistochemical Characterization of Lesional Inflammatory Infiltrate by Clelia Miracco, Francesco Pietronudo, Vasileios Mourmouras, Michele Pellegrino, Monica Onorati, Maria Grazia Mastrogiulio, Luca Cantarini, Pietro Luzi

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Lack of Antilipoprotein Lipase Antibodies in Takayasu's Arteritis by Jozélio Freire de Carvalho, Rosa Maria Rodrigues Pereira, Vilma Santos Trindade Viana, Eloísa Bonfá, Yehuda Shoenfeld

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A 19-year-old Patient with Recurrent Pruritus and Jaundice by K. S. Nezhdanov, E. N. Shirokova, Yu. O. Shulpekova, A. S. Ostrovskaya, M. S. Zharkova, V. T. Ivashkin

“…Workup was negative for viral hepatitis, autoimmune liver diseases, obstructive choledochal lesions, storage diseases, although mutation in gene ABCB11 was found. …”
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Haemophagocytic Lymphohistiocytosis with Leptospirosis: A Rare but Devastating Complication by B. M. Munasinghe, A. G. Arambepola, N. Pathirage, U. P. M. Fernando, N. Subramaniam, S. Nimalan, T. Gajanthan

“…Secondary haemophagocytic lymphohistiocytosis (sHLH), often associated with an array of infections, malignancies, and autoimmune diseases, is rarely seen with leptospirosis, which carries a relatively poor prognosis even with modern state-of-the-art medical care. …”
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Atypical Sjögrenʼs Syndrome Initially Presenting as Lymphocytic Interstitial Pneumonitis followed by Immune Thrombocytopenia by Maham Mehmood, Abhishrut Jog, Masooma Niazi, Arlene Tieng, Giovanni Franchin

“…Sjögrenʼs syndrome is an autoimmune disease characterized primarily by decreased exocrine gland function leading to eye and mouth dryness. …”
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Profiling Serum Cytokines and Anticytokine Antibodies in Psoriasis Patients by Dan Hong, Xiuting Liu, Xiaonan Qiu, Siyao Lu, Yanyun Jiang, Guozhen Tan, Zhenrui Shi, Liangchun Wang

“…Anticytokine autoantibodies (ACAAs) were detected in various autoimmune diseases but remained largely unknown in psoriasis. …”
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CLINICAL CHARACTERISTICS OF DEBUT AND RISK FACTORS OF PEDIATRIC MULTIPLE SCLEROSIS by Валерий Иванович Ларькин, Игорь Иванович Ларькин, Татьяна Аркадьевна Морозова, Степан Евгеньевич Аполлонов

“…Risk factors for MS: family history of MS and autoimmune diseases (AID) in 25 %, obesity in 25 %, concomitant AIDS in 10 %. …”
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Characterization of novel human endogenous retrovirus structures on chromosomes 6 and 7 by Nicholas Pasternack, Nicholas Pasternack, Ole Paulsen, Avindra Nath

“…We examined a cohort of 222 individuals for HML-2 proviruses 6q14.1 and 7p22.1a, two loci that are capable of producing full-length viral proteins and have been previously implicated in several cancers, autoimmune disorders and neurodegenerative diseases, using long-read DNA sequencing. …”
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Quality of Life in Patients with Melasma by Reza Almasi Ghale, Maryam Nasimi, Saeideh Alidoost, Marjan Talebi, Rouzbeh Almasi Ghale, Mehregan Rahmani, Farkhondeh Pouresmaeili

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Safety, Tolerability, and Pharmacokinetics of NIM‐1324 an Oral LANCL2 Agonist in a Randomized, Double‐Blind, Placebo‐Controlled Phase I Clinical Trial by Andrew Leber, Raquel Hontecillas, Nuria Tubau‐Juni, Josep Bassaganya‐Riera

“…ABSTRACT NIM‐1324 is an oral investigational new drug for autoimmune disease that targets the Lanthionine Synthetase C‐like 2 (LANCL2) pathway. …”
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RNAI-MEDIATED SILENCING OF MATRIX METALLOPROTEINASE 1 IN EPIDERMAL KERATINOCYTES INFLUENCES THE BIOLOGICAL EFFECTS OF INTERLEUKIN 17A by J. A. Mogulevtseva, A. V. Mezentsev, S. A. Bruskin

“…Matrix metalloproteinases (MMPs) are important for the pathogenesis of psoriasis and other autoimmune disorders. In the extracellular matrix, accumulation of proinflammatory cytokines, such as interleukin 17A (IL-17A), leads to induction of several MMPs, including MMP1. …”
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A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte by Letizia Mezzasoma, Cinzia Antognelli, Vincenzo Nicola Talesa

“…Dysregulation of both IL-1β and its related pathways is involved in inflammatory/autoimmune disorders and in a wide range of other diseases. …”
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Clinical Characterization of Patients with Chronic Spontaneous Urticaria according to Anti-TPO IgE Levels by Jorge Sánchez, Andres Sánchez, Ricardo Cardona

“…Chronic spontaneous urticaria (CSU) is a heterogeneous disease with some frequent comorbidities like autoimmune diseases, drug reactions, and inducible urticaria. …”
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Navigating large-volume subcutaneous injections of biopharmaceuticals: a systematic review of clinical pipelines and approved products by Philip Green, Andreas Schneider, Jakob Lange

“…These LVSCs are designed to target cancer and a range of non-cancer chronic disease states, including autoimmune, neurological, and cardiovascular diseases. …”
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Synthesis of Interleukin-10 in Patients with Ulcerative Colitis and Helicobacter pylori Infection by Jesús K. Yamamoto-Furusho, Gabriela Fonseca-Camarillo, Carlos A. Barrera-Ochoa, Janette Furuzawa-Carballeda

“…Epidemiological evidence suggests a relationship between Helicobacter pylori infection with the development of autoimmune diseases. H. pylori elicit a chronic systemic inflammatory response with the secretion of proinflammatory cytokines. …”
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Osteoprotegerin as an Emerging Biomarker of Carotid Artery Stenosis? A Scoping Review with Meta-Analysis by Jerzy Chudek, Marta Pośpiech, Anna Chudek, Michał Holecki, Monika Puzianowska-Kuźnicka

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Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus by Mohammad-Amin Khajezadeh, Gholamreza Zamani, Bobak Moazzami, Zahra Nagahi, Mahdie Mousavi-Torshizi, Vahid Ziaee

“…Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by multisystem involvement, including the nervous system. …”
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Shigella sonnei Bacteremia Presenting with Profound Hepatic Dysfunction by Oluwaseun Shogbesan, Andrew Rettew, Bilal Shaikh, Abdullateef Abdulkareem, Anthony Donato

“…Workup for infectious, autoimmune and medication-induced hepatitis, Wilson’s disease, and hemochromatosis was negative. …”
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Glucose-6-phosphate dehydrogenase deficiency with coinherited Gaucher disease: A rare association by Nupur Parakh, Kusha Sharma, Sunita Sharma, Priti Chatterjee, Varinder Singh

“…Few cases of GD with autoimmune hemolytic anemia have been reported. However, literature on GD with concomitant nonimmune hemolytic anemia is scarce. …”
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