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  1. 81

    The Protective Role of HLA-DRB113 in Autoimmune Diseases by Andreia Bettencourt, Cláudia Carvalho, Bárbara Leal, Sandra Brás, Dina Lopes, Ana Martins da Silva, Ernestina Santos, Tiago Torres, Isabel Almeida, Fátima Farinha, Paulo Barbosa, António Marinho, Manuela Selores, João Correia, Carlos Vasconcelos, Paulo P. Costa, Berta Martins da Silva

    Published 2015-01-01
    “…Autoimmune diseases (AIDs) are characterized by a multifactorial aetiology and a complex genetic background, with the MHC region playing a major role. …”
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    Article
  2. 82
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    Influence of Rapid Urbanization on Thyroid Autoimmune Disease in China by Yingchao Chen, Bing Han, Jie Yu, Yi Chen, Jing Cheng, Chunfang Zhu, Fangzhen Xia, Ningjian Wang, Yingli Lu

    Published 2021-01-01
    “…Background. The prevalence of autoimmune thyroid diseases (AITDs), especially Hashimoto’s thyroiditis (HT), has increased dramatically in China. …”
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    Article
  4. 84

    The impact of gut microbiome on neuro-autoimmune demyelinating diseases by Pouria Abolfazli, Cristina Nkene Apue Nchama, Brandon Lucke-Wold

    Published 2024-10-01
    “…Gut dysbiosis promotes the generation of proinflammatory Th17 cells, contributing to blood–brain barrier (BBB) disruption and central nervous system (CNS) autoimmunity. In MS, an increased presence of Th17 cells correlates with disease severity, accompanied by elevated levels of Streptococcus and a higher Firmicutes/Bacteroidetes ratio. …”
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    Article
  5. 85

    The Function of T Follicular Helper Cells in the Autoimmune Liver Diseases by Lin Li, Panyang Xu, Qi Zhou, Jiancheng Xu

    Published 2020-01-01
    “…When dysregulated, TFH cells may represent an important mechanism that contributes to a heightened humoral response and autoantibody production in autoimmune liver diseases (AILDs). TFH cells participate in the immune response associated with AILDs by expressing surface receptors such as programmed cell death protein-1, C-X-C motif chemokine receptor 5, and inducible T cell costimulators, as well as cytokines such as interleukin-21. …”
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    Article
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    Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation by Yi Shen, Changli Lu, Ruoting Men, Jianping Liu, Tinghong Ye, Li Yang

    Published 2018-01-01
    “…To study the differences between acute presentation-autoimmune hepatitis (A-AIH) and chronic autoimmune hepatitis (C-AIH). …”
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    Article
  8. 88

    NK Cell Subtypes as Regulators of Autoimmune Liver Disease by Guohui Jiao, Bangmao Wang

    Published 2016-01-01
    “…However, the precise regulatory mechanisms at work in autoimmune liver diseases remain to be identified. In this review, we focus on recent research with NK cells and their potential role in the development of autoimmune liver disease.…”
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  13. 93

    Implication of Cytotoxic Helicobacter pylori Infection in Autoimmune Diabetes by Alessandro P. Delitala, Giovanni M. Pes, Hoda M. Malaty, Gavino Pisanu, Giuseppe Delitala, Maria P. Dore

    Published 2016-01-01
    “…No previous study addressed a possible link between H. pylori infection and latent autoimmune diabetes in adults (LADA). In this study, a correlation among H. pylori infection and the risk of autoimmune diabetes in comparison with T2D was investigated. …”
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    Article
  14. 94

    Isotretinoin as a Possible Environmental Trigger to Autoimmunity in Genetically Susceptible Patients by Jocelyn Nugroho, Bahareh Schweiger

    Published 2017-01-01
    “…Various case reports have noted autoimmune diseases succeeding isotretinoin treatment. …”
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    Article
  15. 95

    Autoimmunity promotes chronic lymphocytic leukemia progression in an indolent disease model by Lisa Pfeuffer, Viola Siegert, Riccardo Trozzo, Katja Steiger, Roland Rad, Jürgen Ruland, Maike Buchner

    Published 2025-02-01
    “…This study investigates the connection between plasma cell-mediated autoimmunity and CLL progression using a mouse model that expresses an active Receptor Activator of NF-κB (RANK) in B cells (RK mice), where autoimmune manifestations coexist with CLL. …”
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    Article
  16. 96

    Paraneoplastic Autoimmunity Associated with Testicular Myeloid Sarcoma and Chronic Myelomonocytic Leukemia by Jeffrey W. Craig, Richard J. Lin

    Published 2013-01-01
    “…Review of the literature identified the association between hematological malignancies, including chronic myelomonocytic leukemia, and paraneoplastic autoimmune phenomena with features similar to polymyalgia rheumatica and rheumatoid arthritis. …”
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    Article
  17. 97

    Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases by Petra Obermayer-Straub, Christian Peer Strassburg, Michael Peter Manns

    Published 2000-01-01
    “…In autoimmune hepatitis (AIH) type 2, liver and/or kidney microsomal (LKM) type 1 autoantibodies are detected and are directed against CYP2D6. …”
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    Article
  18. 98

    A Case of Peripheral Ulcerative Keratitis Associated with Autoimmune Hepatitis by Hamoon Eshraghi, Aria Mahtabfar, Mohammad H. Dastjerdi

    Published 2017-01-01
    “…To describe a case of peripheral ulcerative keratitis in the setting of autoimmune hepatitis and possible overlap syndrome with primary sclerosing cholangitis. …”
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    Article
  19. 99

    A Rare Association of Autoimmune Hemolytic Anemia with Gastric Adenocarcinoma by Kavita Agrawal, Flores Alfonso

    Published 2017-01-01
    “…The impression was autoimmune hemolytic anemia (AIHA). The evaluation of dysphagia with esophagogastroduodenoscopy revealed a single irregular 4 cm malignant appearing ulcerated mass at the incisura angularis of the stomach. …”
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  20. 100

    C-Reactive Protein (CRP) and Autoimmune Disease: Facts and Conjectures by Alexander J. Szalai

    Published 2004-01-01
    “…These latter properties of CRP have long been suspected to contribute to homeostasis and to autoimmune disease. In this article we review and update the evidence generated in CRPtg by our group and in vitro by others' that indicates CRP is more than just an antimicrobial molecule and convenient marker of inflammation - rather, it protects against autoimmunity. …”
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    Article