Autoantibodies in Systemic Autoimmune Disorders by Michael Mahler, Silvia Pierangeli, Pier-Luigi Meroni, Marvin J. Fritzler

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An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders by Mohammed Alghamdi, Doaa Alasmari, Amjad Assiri, Ehab Mattar, Abdullah A. Aljaddawi, Sana G. Alattas, Elrashdy M. Redwan

“…A defect in the clearance system either in terms of efficiency or capacity may occur due to massive cell death, which may result in the accumulation and leakage of PAD enzymes and the citrullinated peptide from the necrotized cell which could be recognized by the immune system, where the immunological tolerance will be avoided and the autoimmune disorders will be subsequently triggered. The induction of autoimmune responses, autoantibody production, and cytokines involved in the major autoimmune diseases will be discussed.…”
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Polycystic Ovary Syndrome May Be an Autoimmune Disorder by Hifsa Mobeen, Nadeem Afzal, Muhammad Kashif

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Takotsubo Cardiomyopathy and Autoimmune Disorders: A Systematic Scoping Review of Published Cases by Mohsen Farjoud Kouhanjani, Seyed Ali Hosseini, Seyedeh Maryam Mousavi, Zahra Noroozi, Paniz Sadeghi, Armita Jokar-Derisi, Mohammad Saleh Jamshidi Mouselou, Meysam Ahmadi, Armin Attar

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Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives by Giuseppe Lopalco, Luca Cantarini, Antonio Vitale, Florenzo Iannone, Maria Grazia Anelli, Laura Andreozzi, Giovanni Lapadula, Mauro Galeazzi, Donato Rigante

“…A complex web of dynamic relationships between innate and adaptive immunity is now evident for many autoinflammatory and autoimmune disorders, the first deriving from abnormal activation of innate immune system without any conventional danger triggers and the latter from self-/non-self-discrimination loss of tolerance, and systemic inflammation. …”
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Utility of CD64 expression on neutrophils as a marker to differentiate infectious versus noninfectious disease flares in autoimmune disorders by Ashutosh K Mangalam, Rajwardhan Yadav

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Prevalence of Urticarial Diseases in Patients with Coeliac Disease by Eli Magen, Eugene Merzon, Ilan Green, Shlomo Vinker, Ariel Israel

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Myasthenia gravis complicated by pure red cell aplasia with clonal large granular lymphocytosis in the absence of thymoma: a rare case report and literature review by Lijun Du, Yiping Liu, Qiaolin Zhou, Fang Xu

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Distal muscle weakness as the main onset symptom in thymoma-associated myasthenia gravis: a case report and literature review by Xuan Wu, Xiao-tian Xu, Lin Zhou, Kai Qiao, Chong-bo Zhao, Su-shan Luo

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CAR T cells for treating autoimmune diseases by Dimitrios Mougiakakos, Ulrike Koehl, Stephan Fricke, Ulrich Blache, Sandy Tretbar

“…Autoimmune disorders occur when immune cells go wrong and attack the body’s own tissues. …”
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Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets by Sanya Arshad, Benjamin Cameron, Alok V. Joglekar

“…Abstract T cells mediate pathogenesis of several autoimmune disorders by recognizing self-epitopes presented on Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) complex. …”
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Bardet-Biedl Syndrome, Crohn Disease, Primary Sclerosing Cholangitis, and Autoantibody Positive Thyroiditis: A Case Report and A Review of a Cohort of BBS Patients by Ugur Halac, Denise Herzog

“…Although the disease has been described in a patient with psoriasis, individuals with BBS are not known to be at risk of developing autoimmune disorders. Our objective was to describe a 14-year-old patient with BBS who presented with Crohn disease (CD), primary sclerosing cholangitis (PSC), and thyroiditis in the context of a cohort review at Sainte-Justine Hospital and to alert clinicians to the increased risk of autoimmune disorders in these patients. …”
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Peroxisome Proliferator-Activated Receptor-γ in Thyroid Autoimmunity by Silvia Martina Ferrari, Poupak Fallahi, Roberto Vita, Alessandro Antonelli, Salvatore Benvenga

“…However, further studies are ongoing to explore the use of new PPAR-γ agonists in the treatment of thyroid autoimmune disorders.…”
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Human immune system: Exploring diversity across individuals and populations by Kim Han Hoang Nguyen, Nghi Vinh Le, Phuc Hoang Nguyen, Hien Hau Thi Nguyen, Duy Mai Hoang, Chien Dinh Huynh

“…The presence of genetic diversity, particularly across different ethnic and racial groups, significantly contributes to the impact of incidence of diseases, disease susceptibility, autoimmune disorders, and cancer risks in specific regions and certain populations. …”
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Keeping an Eye on Crohn’s Disease: Orbital Myositis as the Presenting Symptom by Carol A Durno, Robert Ehrlich, Robert Taylor, J Raymond Buncic, Peter Hughes, Anne Marie Griffiths

“…Episodic periorbital swelling due to presumed orbital inflammation and myositis caused intermittent apparent proptosis and was the presenting symptom of ileocecal Crohn's disease (CD) in a teenage female with a family history of autoimmune disorders and CD. Orbital myositis, a very rare extraintestinal manifestation of inflammatory bowel disease (IBD), likely represents a process of impaired immunoregulation related to the underlying intestinal inflammation. …”
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Hemophagocytic lymphohistiocytosis secondary to refractory acute myeloid leukemia resolved after second line treatment with azacitidine plus venetoclax by Claudio Fozza

“…Secondary HLH typically occurs in conjunction with severe infections, malignancies or autoimmune disorders and intensive chemotherapy, potentially complicating treatment of acute myeloid leukemia (AML) in around 10% of cases. …”
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Urticarial Vasculitis-Associated Intestinal Ischemia by Uni Wong, Harris Yfantis, Guofeng Xie

“…UV is often idiopathic but can also present in the context of autoimmune disorders such as systemic lupus erythematosus, drug reactions, infections, or a paraneoplastic syndrome. …”
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Acquired von Willebrand Syndrome in IgM Monoclonal Gammopathy as the Presentation of Lymphoplasmacytic Lymphoma by Zachary Wolfe, Bradley Lash

“…Most commonly implicated are lymphoproliferative, myeloproliferative, cardiovascular, and autoimmune disorders. Unlike inherited von Willebrand disease (vWD), AVWS tends to present at an older age and without a family history of vWD. …”
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Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis by Parvin Mansouri, Farahnaz Bidari‐Zerehpoosh, Nikoo Mozafari

“…ABSTRACT Tumor necrosis factor‐alpha (TNF‐α) inhibitors are commonly used for management of various autoimmune disorders but can rarely cause isolated cutaneous lupus. …”
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Multicentric Castleman’s Disease, Associated with Idiopathic Thrombocytopenic Purpura by Ruchi Sood, Harris C. Taylor, Hamed Daw

“…We present the third known association between MCD and previous immune thrombocytopenia in the absence of HIV and HHV-8 infection and review its association with other autoimmune disorders and attendant implications for pathogenesis. …”
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