Suggested Topics within your search.
Showing 481 - 500 results of 674 for search '"autoimmune disease"', query time: 0.05s Refine Results
  1. 481
  2. 482
  3. 483

    Gut Microbiome: An Intersection between Human Genome, Diet, and Epigenetics by Abdullahi Y. Muhammad, Malik Amonov, Atif A. Baig, Farrukh J. Alvi

    Published 2024-01-01
    “…Specific genetic variants in genes that are responsible for maintaining the composition of the gut commensal, such as genes of the immune system, are described to result in gut dysbiosis that can lead to the development of several autoimmune diseases such as inflammatory bowel disease and type-1 diabetes. …”
    Get full text
    Article
  4. 484

    Oral supplementation with propionate is reflected in the serum of healthy individuals by Maximilian Schröder, Arijan Pasic, Frank Hirche, Svitlana Rozanova, Melissa Sgodzai, Barbara Gisevius, Lea Horstkemper, Ralf Gold, Katrin Marcus, Kalliopi Pitarokoili, Jeremias Motte, Katalin Barkovits, Gabriele Stangl, Anna Lena Fisse

    Published 2025-01-01
    “…Supplementing PA has shown benefits for autoimmune diseases. A comprehensive understanding of the PA pharmacokinetics is essential for the optimal design and execution of studies utilizing orally administered PA. …”
    Get full text
    Article
  5. 485

    Roles of Lymphocyte Kv1.3-Channels in the Pathogenesis of Renal Diseases and Novel Therapeutic Implications of Targeting the Channels by Itsuro Kazama

    Published 2015-01-01
    “…Using selective channel inhibitors in experimental animal models, in vivo studies then revealed the clinically relevant relationship between the channel expression and the pathogenesis of autoimmune diseases. In renal diseases, in which “chronic inflammation” or “the overstimulation of cellular immunity” is responsible for the pathogenesis, the overexpression of Kv1.3-channels in lymphocytes promotes their cellular proliferation and thus contributes to the progression of tubulointerstitial fibrosis. …”
    Get full text
    Article
  6. 486

    Polycystic Ovary Syndrome May Be an Autoimmune Disorder by Hifsa Mobeen, Nadeem Afzal, Muhammad Kashif

    Published 2016-01-01
    “…There is an association between PCOS and autoimmune diseases such as ANA and anti-TPO that have been documented in systemic lupus erythematosus and Hashimoto thyroiditis, respectively, and it is suspected that there are autoantibodies that might affect the long term clinical management of these patients. …”
    Get full text
    Article
  7. 487

    Whole Exome Sequencing and Molecular Modeling of a Missense Variant in TNFAIP3 That Segregates with Disease in a Family with Chronic Urticaria and Angioedema by Antoneicka L. Harris, Patrick R. Blackburn, John E. Richter, Jennifer M. Gass, Thomas R. Caulfield, Ahmed N. Mohammad, Paldeep S. Atwal

    Published 2018-01-01
    “…Variants in TNFAIP3 have been associated with multiple autoimmune diseases, susceptibility to allergy and asthma, and periodic fever syndromes, suggesting that this variant could potentially play a role in disease.…”
    Get full text
    Article
  8. 488

    Innate and Adaptive Cell Populations Driving Inflammation in Dry Eye Disease by José L. Reyes, Danielle T. Vannan, Bertus Eksteen, Imelda Juárez Avelar, Tonathiu Rodríguez, Marisol Ibet González, Alicia Vázquez Mendoza

    Published 2018-01-01
    “…In its secondary form, DED is often associated with autoimmune diseases such as Sjögren’s syndrome and rheumatoid arthritis. …”
    Get full text
    Article
  9. 489

    Exploring the interactions of rapamycin with target receptors in A549 cancer cells: insights from molecular docking analysis by Sanjeev K. Ganesh, C. Subathra Devi

    Published 2025-01-01
    “…This could also facilitate in understanding the possible action mechanisms of rapamycin in other diseases such as neurovegetative diseases, autoimmune diseases, etc.…”
    Get full text
    Article
  10. 490

    Successful Modified Therapy in a Patient with Probable Infection-Associated Hemophagocytic Lymphohistiocytosis by Carl L. Kay, Matthew J. Rendo, Paul Gonzales, Sead G. Beganovic, Magdalena Czader

    Published 2019-01-01
    “…In adults, HLH is typically a complication of infections, autoimmune diseases, and malignancies. While the disease is often fatal, classic management of HLH revolves around early diagnosis and initiation of protocolized therapy. …”
    Get full text
    Article
  11. 491

    A Comprehensive Dataset on Microbiome Dynamics in Rheumatoid Arthritis from a Large-Scale Cohort Study by Jing Li, Jun Xu, Jiayang Jin, Congmin Xu, Yuzhou Gan, Yifan Wang, Ruiling Feng, Wenqiang Fan, Yingni Li, Xiaozhen Zhao, Yucui Li, Shushi Gong, Linchong Su, Yueming Cai, Lianjie Shi, Xiaolin Sun, Yang Xiang, Qingwen Wang, Ru Li, Jinxia Zhao, Yulan Liu, Junjie Qin, Zhanguo Li, Jing He

    Published 2025-02-01
    “…This large-scale dataset is expected to be a foundation for collaborative research, advancing our understanding of the microbiome’s systemic effects in RA and other autoimmune diseases and potentially guiding new therapeutic approaches.…”
    Get full text
    Article
  12. 492

    Hemophagocytic Lymphohistiocytosis Associated with Respiratory Syncytial Virus Infection in an Immunocompetent Elderly Patient by Ralph Kamel, Rubal Sharma, Divya Asti, Arshpal Gill, Yevgeniy Skaradinskiy

    Published 2020-01-01
    “…The secondary form presents later in life and is associated with several conditions mainly malignancy, autoimmune diseases, viral or bacterial infections, and hematological diseases. …”
    Get full text
    Article
  13. 493

    Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis by Elisabetta Volpe, Luca Battistini, Giovanna Borsellino

    Published 2015-01-01
    “…The discovery of the T helper (Th) 17 lineage, involved in the protection against fungal and extracellular bacterial infections, has profoundly revolutionized our current understanding of T cell-mediated responses in autoimmune diseases, including multiple sclerosis (MS). …”
    Get full text
    Article
  14. 494

    Atypical Celiac Disease: From Recognizing to Managing by B. Admou, L. Essaadouni, K. Krati, K. Zaher, M. Sbihi, L. Chabaa, B. Belaabidia, A. Alaoui-Yazidi

    Published 2012-01-01
    “…The availability of high-sensitive and specific serologic tests such as antitissue transglutuminase, antiendomysium, and more recent antideamidated, gliadin peptide antibodies permits to efficiently uncover a large portion of the submerged CD iceberg, including individuals having conditions associated with a high risk of developing CD (type 1 diabetes, autoimmune diseases, Down syndrome, family history of CD, etc.), biologic abnormalities (iron deficiency anemia, abnormal transaminase levels, etc.), and extraintestinal symptoms (short stature, neuropsychiatric disorders, alopecia, dental enamel hypoplasia, recurrent aphtous stomatitis, etc.). …”
    Get full text
    Article
  15. 495

    The Association of −330 Interleukin-2 Gene Polymorphism with Its Plasma Concentration in Iranian Multiple Sclerosis Patients by Arezou Sayad, Abolfazl Movafagh

    Published 2014-01-01
    “…The cytokine genes are involved in autoimmune diseases such as MS. In this study, we report the influence of −330 interleukin-2 (IL2) gene polymorphism on its plasma levels in a group of Iranian MS patients. …”
    Get full text
    Article
  16. 496

    Autoimmune Polyendocrine Syndrome 3 Onset with Severe Ketoacidosis in a 74-Year-Old Woman by Stefano Benedini, Antonietta Tufano, Elena Passeri, Marco Mendola, Livio Luzi, Sabrina Corbetta

    Published 2015-01-01
    “…It is noteworthy that an APS3 acute episode occurred in an asymptomatic elder woman for any autoimmune diseases.…”
    Get full text
    Article
  17. 497

    Antigenic Complementarity in the Origins of Autoimmunity: A General Theory Illustrated With a Case Study of Idiopathic Thrombocytopenia Purpura by Robert Root-Bernstein, Jacob Couturier

    Published 2006-01-01
    “…Finally, we argue that Koch's postulates are inadequate for establishing disease causation for multiple-antigen diseases and discuss the possibility that current research has failed to elucidate the causes of human autoimmune diseases because we are using the wrong criteria.…”
    Get full text
    Article
  18. 498

    The Roles of Thyroid and Thyroid Hormone in Pancreas: Physiology and Pathology by Chaoran Chen, Zhenxing Xie, Yingbin Shen, Shu Fang Xia

    Published 2018-01-01
    “…Afterwards, epidemiological investigations and animal test research found a link between autoimmune diseases, thyroid dysfunction, and pancreas pathology; however, the underlying mechanisms remain unknown. …”
    Get full text
    Article
  19. 499

    sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway by Yatao Bao, Meng Lian, Yong Chen, Xiaotian Gu, Kunyu Cao, Xiaoping Du, Jiyu Ju

    Published 2023-01-01
    “…Collectively, our study revealed the impact of sNASP gene mutation on the sensitivity of TLR4 receptors in mouse peritoneal macrophages and shed light on potential mechanisms underlying inflammation in autoimmune diseases.…”
    Get full text
    Article
  20. 500

    The Expression of Selected Proapoptotic Molecules in Dermatitis Herpetiformis by Zebrowska Agnieszka, Erkiert-Polguj Anna, Wagrowska-Danilewicz Malgorzata, Danilewicz Marian, Sysa-Jedrzejowska Anna, Anna Cynkier, Waszczykowska Elzbieta

    Published 2012-01-01
    “…The role of the process of apoptosis is investigated in the pathogenesis of many autoimmune diseases; however at present, there is not much information about its role in dermatitis herpetiformis. …”
    Get full text
    Article