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481
The Videofluorographic Swallowing Study in Rheumatologic Diseases: A Comprehensive Review
Published 2017-01-01“…Inflammation in autoimmune diseases may lead to serious damage to other organs including the gastrointestinal tract. …”
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482
Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus
Published 2025-02-01“…Notably, CSTB has emerged as a differential biomarker, distinguishing between these two autoimmune diseases.…”
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483
Gut Microbiome: An Intersection between Human Genome, Diet, and Epigenetics
Published 2024-01-01“…Specific genetic variants in genes that are responsible for maintaining the composition of the gut commensal, such as genes of the immune system, are described to result in gut dysbiosis that can lead to the development of several autoimmune diseases such as inflammatory bowel disease and type-1 diabetes. …”
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484
Oral supplementation with propionate is reflected in the serum of healthy individuals
Published 2025-01-01“…Supplementing PA has shown benefits for autoimmune diseases. A comprehensive understanding of the PA pharmacokinetics is essential for the optimal design and execution of studies utilizing orally administered PA. …”
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485
Roles of Lymphocyte Kv1.3-Channels in the Pathogenesis of Renal Diseases and Novel Therapeutic Implications of Targeting the Channels
Published 2015-01-01“…Using selective channel inhibitors in experimental animal models, in vivo studies then revealed the clinically relevant relationship between the channel expression and the pathogenesis of autoimmune diseases. In renal diseases, in which “chronic inflammation” or “the overstimulation of cellular immunity” is responsible for the pathogenesis, the overexpression of Kv1.3-channels in lymphocytes promotes their cellular proliferation and thus contributes to the progression of tubulointerstitial fibrosis. …”
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486
Polycystic Ovary Syndrome May Be an Autoimmune Disorder
Published 2016-01-01“…There is an association between PCOS and autoimmune diseases such as ANA and anti-TPO that have been documented in systemic lupus erythematosus and Hashimoto thyroiditis, respectively, and it is suspected that there are autoantibodies that might affect the long term clinical management of these patients. …”
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487
Whole Exome Sequencing and Molecular Modeling of a Missense Variant in TNFAIP3 That Segregates with Disease in a Family with Chronic Urticaria and Angioedema
Published 2018-01-01“…Variants in TNFAIP3 have been associated with multiple autoimmune diseases, susceptibility to allergy and asthma, and periodic fever syndromes, suggesting that this variant could potentially play a role in disease.…”
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488
Innate and Adaptive Cell Populations Driving Inflammation in Dry Eye Disease
Published 2018-01-01“…In its secondary form, DED is often associated with autoimmune diseases such as Sjögren’s syndrome and rheumatoid arthritis. …”
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489
Exploring the interactions of rapamycin with target receptors in A549 cancer cells: insights from molecular docking analysis
Published 2025-01-01“…This could also facilitate in understanding the possible action mechanisms of rapamycin in other diseases such as neurovegetative diseases, autoimmune diseases, etc.…”
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490
Successful Modified Therapy in a Patient with Probable Infection-Associated Hemophagocytic Lymphohistiocytosis
Published 2019-01-01“…In adults, HLH is typically a complication of infections, autoimmune diseases, and malignancies. While the disease is often fatal, classic management of HLH revolves around early diagnosis and initiation of protocolized therapy. …”
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491
A Comprehensive Dataset on Microbiome Dynamics in Rheumatoid Arthritis from a Large-Scale Cohort Study
Published 2025-02-01“…This large-scale dataset is expected to be a foundation for collaborative research, advancing our understanding of the microbiome’s systemic effects in RA and other autoimmune diseases and potentially guiding new therapeutic approaches.…”
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492
Hemophagocytic Lymphohistiocytosis Associated with Respiratory Syncytial Virus Infection in an Immunocompetent Elderly Patient
Published 2020-01-01“…The secondary form presents later in life and is associated with several conditions mainly malignancy, autoimmune diseases, viral or bacterial infections, and hematological diseases. …”
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493
Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis
Published 2015-01-01“…The discovery of the T helper (Th) 17 lineage, involved in the protection against fungal and extracellular bacterial infections, has profoundly revolutionized our current understanding of T cell-mediated responses in autoimmune diseases, including multiple sclerosis (MS). …”
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494
Atypical Celiac Disease: From Recognizing to Managing
Published 2012-01-01“…The availability of high-sensitive and specific serologic tests such as antitissue transglutuminase, antiendomysium, and more recent antideamidated, gliadin peptide antibodies permits to efficiently uncover a large portion of the submerged CD iceberg, including individuals having conditions associated with a high risk of developing CD (type 1 diabetes, autoimmune diseases, Down syndrome, family history of CD, etc.), biologic abnormalities (iron deficiency anemia, abnormal transaminase levels, etc.), and extraintestinal symptoms (short stature, neuropsychiatric disorders, alopecia, dental enamel hypoplasia, recurrent aphtous stomatitis, etc.). …”
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495
The Association of −330 Interleukin-2 Gene Polymorphism with Its Plasma Concentration in Iranian Multiple Sclerosis Patients
Published 2014-01-01“…The cytokine genes are involved in autoimmune diseases such as MS. In this study, we report the influence of −330 interleukin-2 (IL2) gene polymorphism on its plasma levels in a group of Iranian MS patients. …”
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496
Autoimmune Polyendocrine Syndrome 3 Onset with Severe Ketoacidosis in a 74-Year-Old Woman
Published 2015-01-01“…It is noteworthy that an APS3 acute episode occurred in an asymptomatic elder woman for any autoimmune diseases.…”
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497
Antigenic Complementarity in the Origins of Autoimmunity: A General Theory Illustrated With a Case Study of Idiopathic Thrombocytopenia Purpura
Published 2006-01-01“…Finally, we argue that Koch's postulates are inadequate for establishing disease causation for multiple-antigen diseases and discuss the possibility that current research has failed to elucidate the causes of human autoimmune diseases because we are using the wrong criteria.…”
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498
The Roles of Thyroid and Thyroid Hormone in Pancreas: Physiology and Pathology
Published 2018-01-01“…Afterwards, epidemiological investigations and animal test research found a link between autoimmune diseases, thyroid dysfunction, and pancreas pathology; however, the underlying mechanisms remain unknown. …”
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499
sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway
Published 2023-01-01“…Collectively, our study revealed the impact of sNASP gene mutation on the sensitivity of TLR4 receptors in mouse peritoneal macrophages and shed light on potential mechanisms underlying inflammation in autoimmune diseases.…”
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500
The Expression of Selected Proapoptotic Molecules in Dermatitis Herpetiformis
Published 2012-01-01“…The role of the process of apoptosis is investigated in the pathogenesis of many autoimmune diseases; however at present, there is not much information about its role in dermatitis herpetiformis. …”
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