Statins as Modulators of Regulatory T-Cell Biology by David A. Forero-Peña, Fredy R. S. Gutierrez

“…On the other hand, the induction and activity of regulatory T cells (Treg) are key processes in the prevention of pathology during chronic inflammatory and autoimmune diseases. Hence, strategies oriented towards the therapeutic expansion of Tregs are gaining special attention among biomedical researchers. …”
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CD19-directed chimeric antigen receptor T-cell therapy: what can we learn from the haematologist? by Marie José Kersten, Maria Theresa Kuipers

“…CD19-directed chimeric antigen receptor (CAR) T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for patients with autoimmune diseases. By selectively depleting CD19-positive B-cells, this therapy brings a new approach in resetting immune dysregulation and potentially providing long-term remission for patients with a refractory disease. …”
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Lipid metabolism in myeloid cell function and chronic inflammatory diseases by Ayaka Ito, Ayaka Ito, Ayaka Ito, Takayoshi Suganami, Takayoshi Suganami, Takayoshi Suganami, Takayoshi Suganami

“…Understanding the mechanism by which lipids regulate immune cell function might provide novel therapeutic insights into chronic inflammatory diseases, including metabolic diseases, autoimmune diseases and cancer. (143 words)…”
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Role of RING-Type E3 Ubiquitin Ligases in Inflammatory Signalling and Inflammatory Bowel Disease by Liguo Zhu, Ying Li, Longyuan Zhou, Guang Yang, Ying Wang, Jing Han, Li Li, Shenghong Zhang

“…These processes also occur in autoimmune diseases, especially inflammatory bowel disease (IBD). …”
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Targeting Toll-Like Receptors for Treatment of SLE by Christopher G. Horton, Zi-jian Pan, A. Darise Farris

“…Genome-wide association studies, single nucleotide polymorphism analyses as well as experimental mouse models have provided evidence of TLR signaling involvement in SLE and other autoimmune diseases. Since activation of these receptor pathways promotes autoimmune phenotypes, inhibitory drugs that target these pathways constitute important new therapeutic strategies for the treatment of systemic autoimmunity.…”
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Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia by Irene Mavroudi, Helen A. Papadaki

“…Increasing interest on the field of autoimmune diseases has unveiled a plethora of genetic factors that predispose to these diseases. …”
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Case report: Scleromalacia caused by rheumatoid arthritis combined with high intraocular pressure, first discovered due to ocular trauma by Yanyan Zhang, Yanyan Wang, Ruihao Xu, Tianyu Wang, Yuhao Zhang, Jinghai Mao, Quanyong Yi

“…This case once again underscores the importance of clinicians paying close attention to the impact of systemic autoimmune diseases on ocular health.…”
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Successful Management of Acquired Hemophilia A Associated with Bullous Pemphigoid: A Case Report and Review of the Literature by Quentin Binet, Catherine Lambert, Laurine Sacré, Stéphane Eeckhoudt, Cedric Hermans

“…About half the cases are associated with pregnancy, postpartum, autoimmune diseases, malignancies, or adverse drug reactions. …”
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Type 2 Inflammatory Responses in Autoimmune Demyelination of the Central Nervous System: Recent Advances by Massimo Costanza

“…However, growing evidence suggests that cells and mediators typically associated with type 2 inflammation are involved in several physiopathological conditions, such as defense against toxic substances, anticancer immunity, and autoimmune diseases. In neuromyelitis optica, an autoimmune demyelinating disorder of the spinal cord and optic nerve, eosinophils extensively infiltrate lesions in the central nervous system (CNS) and promote tissue pathology in experimental models of this disease. …”
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Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets by Sanya Arshad, Benjamin Cameron, Alok V. Joglekar

“…Recent advances in immunopeptidomics have started to unravel the repertoire of antigenic epitopes presented on MHC. In several autoimmune diseases, immunopeptidomics has led to the identification of novel autoantigens and has enhanced our understanding of the mechanisms behind autoimmunity. …”
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Role of Adaptive Immunity in Alcoholic Liver Disease by Emanuele Albano

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Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review by Miaomiao Yang, Jiannan Liu

“…Potential mechanisms for the development of dermatomyositis and novel insights neoplastic autoimmune diseases were proposed.…”
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Mycoplasma Pneumonia: An Unrecognized Cause of Fever of Unknown Origin in an Adult by Fatima Ali-Ahmed, Alexandra Halalau

“…She had no respiratory symptoms or family history of autoimmune diseases. A chest X-ray was negative for pneumonia or hilar adenopathy. …”
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Unexpected cause of headache in a patient with Noonan syndrome: aseptic meningitis by Hacer Efnan Melek Arsoy, Öner Özdemir, Ümmügülsüm Dikici, Ece Tüsüz Önata, Recep Polat

“…Malignancies, autoimmune diseases, viral and fungal infections, as well as aseptic meningitis due to certain drugs are frequently seen. …”
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Isotretinoin as a Possible Environmental Trigger to Autoimmunity in Genetically Susceptible Patients by Jocelyn Nugroho, Bahareh Schweiger

“…Various case reports have noted autoimmune diseases succeeding isotretinoin treatment. Case Report. …”
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Severe Late-Onset Drug-Induced Immune Thrombocytopenia Following IFN β-1a Treatment: A Case Report of a 52-Year-Old Woman with Relapse-Remitting Multiple Sclerosis by Christophe Cisarovsky, Marie Théaudin, Pierre-Alexandre Bart, Grégoire Stalder, Lorenzo Alberio

“…Blood work showed an isolated severe thrombocytopenia and ruled out other autoimmune diseases, viral infections, intravascular hemolysis, and renal impairment. …”
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Interactions of the Intestinal Epithelium with the Pathogen and the Indigenous Microbiota: A Three-Way Crosstalk by C. V. Srikanth, Beth A. McCormick

“…Even slight perturbations in this equilibrium may be detrimental to the host leading to severe bacterial infection or even autoimmune diseases like inflammatory bowel disease. Several experimental model systems, including germ-free mice and antibiotic-treated mice, have been used by various researchers to study this complex relationship. …”
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Multiple Transverse Colonic Perforations Associated with Slow-Release Nonsteroidal Anti-Inflammatory Drugs and Corticosteroids: A Case Report by Nobuki Shioya, Shigehiro Shibata, Masahiro Kojika, Shigeatsu Endo

“…The present case highlights the need for exercising caution while prescribing slow-release nonsteroidal anti-inflammatory drugs with corticosteroids to patients with autoimmune diseases, as such treatment may exacerbate intestinal epithelial abnormalities.…”
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Gut microbiota-derived metabolites and chronic inflammatory diseases by Alejandra Vargas, Benjamin L. Robinson, Kevin Houston, Ana Rosa Vilela Sangay, Michael Saadeh, Steve D’Souza, David A. Johnson

“…Disruption of this microbial balance, known as dysbiosis, has been increasingly implicated in the pathogenesis of chronic inflammatory conditions, including cardiovascular, gastrointestinal, and autoimmune diseases, as well as metabolic disorders such as diabetes and obesity. …”
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Chemogenomics for steroid hormone receptors (NR3) by Espen Schallmayer, Laura Isigkeit, Lewis Elson, Susanne Müller, Stefan Knapp, Julian A. Marschner, Daniel Merk

“…Although several NR3 ligands such as glucocorticoids are invaluable drugs, this family is only partially explored, for example, in autoimmune diseases and neurodegeneration, but may hold therapeutic potential in new areas. …”
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