Incidence of alexithymia in worsening symptoms and quality of life of Systemic Lupus Erythematosus patients (SLE) by Fabio Rapisarda, Concetta Mezzatesta, Antonina Butticè, Alessandro Raffa, Stefano Boca

“…Background and Objectives: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease affecting connective tissues, with the potential to impact various organs and systems, thereby limiting the quality of life for affected individuals given that it influences their psychological well-being. …”
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Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

“…They have increasingly gained recognition for their novel roles in the immune system, especially under autoimmune conditions. Conventional machine learning approaches such as principal component analysis have been employed in single-cell RNA sequencing (scRNA-seq) analysis to characterize DNT cells. …”
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Beclin-1 as a potential prognostic marker in correlation with E-cadherin in oral lichen planus and oral squamous cell carcinoma: an immunohistochemical analysis by Heba N. Shalash, Radwa R. Hussein, Fatma Seragel-Deen

“…Background/aim Oral lichen planus (OLP) is a chronic, unexceptional, frequent disease of inflammatory origin, autoimmune background with unspecified etiology. Also it has been regarded as an oral potentially malignant disorder and reflects the potential hazard of malignant transformation into oral squamous cell carcinoma (OSCC). …”
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Intravenous Immunoglobulin Therapy Administered Early after Narcolepsy Type 1 Onset in Three Patients Evaluated by Clinical and Polysomnographic Follow-Up by Elisabeth Ruppert, Hélène Zagala, Juliette Chambe, Henri Comtet, Ulker Kilic-Huck, François Lefebvre, Marc Bataillard, Carmen Schroder, Laurent Calvel, Patrice Bourgin

“…Patients have a selective degeneration of hypocretin-producing neurons in the dorsolateral posterior hypothalamus with growing evidence supporting the hypothesis of an autoimmune mechanism. Few case studies that reported intravenous immunoglobulin therapy (IVIg) suggest the efficacy of IVIg when administered early after disease onset, but the results are controversial. …”
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Exploring the comorbidity mechanisms between atherosclerosis and hashimoto’s thyroiditis based on microarray and single-cell sequencing analysis by Yirong Ma, Shuguang Wu, Junyu Lai, Qiang Wan, Jingxuan Hu, Yanhong Liu, Ziyi Zhou, Jianguang Wu

“…Hashimoto’s thyroiditis (HT) is an autoimmune disorder marked by chronic inflammation and destruction of thyroid tissue. …”
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Peroxiredoxin 6 Attenuates Alloxan-Induced Type 1 Diabetes Mellitus in Mice and Cytokine-Induced Cytotoxicity in RIN-m5F Beta Cells by Elena G. Novoselova, Olga V. Glushkova, Sergey M. Lunin, Maxim O. Khrenov, Svetlana B. Parfenyuk, Tatyana V. Novoselova, Mars G. Sharapov, Vladimir I. Novoselov, Evgeny E. Fesenko

“…Type 1 diabetes is associated with the destruction of pancreatic beta cells, which is mediated via an autoimmune mechanism and consequent inflammatory processes. …”
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Ultrasonic color Doppler imaging to assess the efficacy of orbital decompression in Graves’ ophthalmopathy by A.A. Kalandari, A.G. Nosova, N.Yu. Kutrovskaya, O.V. Levchenko

“…Changes in linear blood flow velocity in the superior ophthalmic vein are an additional diagnostic criterion for the severity of autoimmune disorder in these patients. Abnormalities of venous blood flow promote non-inflammatory edema of retrobulbar fat, proptosis, and orbital compression. …”
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The Effectiveness of Mindfulness-Based Stress Reduction Therapy on Disease signs and Symptoms and Psychological Distress in Women with Oral Lichen Planus by Fatemeh Sarebannezhad, Abdollah Omidi, Zahra Zanjani, Elaheh Ghasemzadeh Hoseini, Narges Gholizadeh

“…Background and purpose: Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease that, although not typically life-threatening, can lead to significant psychosocial consequences. …”
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How do serum cytokine levels change in myocarditis and inflammatory dilated cardiomyopathy relative to healthy individuals? A protocol for a systematic review and meta-analysis by Romuald Wojnicz, Piotr Lewandowski, Maciej Baron, Marcin A Rojek, Marcin Goławski, Karol Krystek, Magdalena Żegleń, Pascal Zytkiewicz, Jakub Kancerek, Klaudia Gabriela Lis, Jakub Warecki, Jakub Kufel, Kamila Kuśpiel

“…Introduction Myocarditis is an inflammatory heart disease resulting from infections, toxic exposures or autoimmune reactions. Irrespective of the factors responsible for this disease, cytokines play an important role in regulating the immunological response involved in its development and progression. …”
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Diagnostics and treatment of cardiac achalasia and cardiospasm: guidelines of the Russian gastroenterological association by V. T. Ivashkin, A. S. Trukhmanov, E. A. Godzhello, I. V. Mayev, Yu. V. Evsyutina, T. L. Lapina, O. A. Storonova

“…Three main hypotheses of disease etiology are discussed: genetic, contagious and autoimmune. Clinical symptoms of disease: difficulty of passage of solid and liquid food through the esophagus, vomiting, in certain cases - chest pain; severe disease is accompanied by cough and weight loss. …”
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New Potential Weapons for Refractory Scleritis in the Era of Targeted Therapy by Claudia Fabiani, Jurgen Sota, Maite Sainz-de-la-Maza, Laura Pelegrín, Giacomo Emmi, Giuseppe Lopalco, Florenzo Iannone, Lorenzo Vannozzi, Silvana Guerriero, Maria Chiara Gelmi, Donato Rigante, Gian Marco Tosi, José Hernández-Rodríguez, Luca Cantarini

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Clinical features of autonomic dysfunction in children with anti-N-methyl-D aspartic receptor encephalitis by Dongqing Li, Jing Sun, Guannan Li, Shuo Miao, Jian Yang, Jianzhao Zhang

“…Abstract Background Anti-N-methyl-D-aspartic receptor encephalitis (Anti-NMDAR encephalitis) is the most prevalent form of autoimmune encephalitis in pediatric patients. Autonomic dysfunction is a frequent symptom of Anti-NMDAR encephalitis, yet it often goes unnoticed by pediatricians. …”
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A higher incidence of cardiovascular complications in hyperthyroid patients with Graves’ disease in comparison to hyperthyroid patients with subacute thyroiditis by Ana Šešek, Simona Gaberšček, Katja Zaletel, Edvard Pirnat, Katica Bajuk Studen

“…However, in Graves’ disease, there is an autoimmune process in the thyroid, and in subacute thyroiditis, hyperthyroidism is accompanied by systemic inflammation. …”
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Autoinflammatory diseases. Part 1: concept, classification, immunobiology, diagnosis by O.V. Shvaratska, M.V. Kalichevska, O.V. Klymenko, O.M. Taran, O.V. Klimova, Y.V. Vilenskyi, T.M. Plekhanova, T.K. Mavropulo

“…Recently, some molecular mechanisms typical for autoinflammation have also been recognized in the pathogenesis of several autoimmune and immunodeficiency states. This scientific review aimed to systematize current ideas about autoinflammatory diseases to increase medical professionals’ awareness regarding the issue, which is significantly lower than that of other categories of immune dysfunction. …”
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Prognostic Factors for Clinical Response in Systemic Lupus Erythematosus Patients Treated by Allogeneic Mesenchymal Stem Cells by Lihui Wen, Myriam Labopin, Manuela Badoglio, Dandan Wang, Lingyun Sun, Dominique Farge-Bancel

“…Systemic lupus erythematosus (SLE) is an autoimmune disease with a broad range of clinical manifestations and a heterogeneous disease course. …”
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New onset of isolated adrenocorticotropin deficiency associated with encephalopathy following coronavirus disease 2019 in a healthy elderly man by Yusuke Yamasaki, Ichiro Horie, Riyoko Shigeno, Shinpei Nishikido, Toshiyuki Ikeoka, Takuro Hirayama, Yohei Tateishi, Akira Tsujino, Atsushi Kawakami

“…His encephalopathy might have developed via a disturbance of the autoimmune system, or a metabolic effect associated with adrenal insufficiency, although the time lag between the hyponatremia’s improvement and the patient’s neurological response to the steroid was incompatible with common cases of delirium concurrent with adrenal insufficiency. …”
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Unveiling Cuproptosis-Driven Molecular Clusters and Immune Dysregulation in Ankylosing Spondylitis by Wei B, Wang S, Li S, Gu Q, Yue Q, Tang Z, Zhang J, Liu W

“…Bowen Wei,1,2,* Siwei Wang,1,2,* Suiran Li,1,2,* Qingxiang Gu,3 Qingyun Yue,4 Zhuo Tang,1,2 Jiamin Zhang,1,2 Wei Liu1,2 1Department of Rheumatism and Immunity, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China; 2National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, People’s Republic of China; 3Center of Preventive Treatment of Disease, Cangzhou Hospital of Integrated Traditional Chinese and Western of Hebei Province, Cangzhou, Hebei, People’s Republic of China; 4School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Liu, Email fengshiliuwei@163.comBackground: Ankylosing spondylitis (AS) is a chronic autoimmune disease characterized by inflammation of the sacroiliac joints and spine. …”
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Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction by Veronica Marcos, Zhe Zhou-Suckow, Ali Önder Yildirim, Alexander Bohla, Andreas Hector, Ljubomir Vitkov, Wolf Dietrich Krautgartner, Walter Stoiber, Matthias Griese, Oliver Eickelberg, Marcus A. Mall, Dominik Hartl

“…On the other hand, excessive NET formation has been linked to the pathogenesis of autoinflammatory and autoimmune disease conditions. We quantified free DNA structures characteristic of NETs in airway fluids of CF patients and a mouse model with CF-like lung disease. …”
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Biosimilars in Focus: Evaluating Their Role Compared to Adalimumab in Clinical Practice by Dorota Waz, Michał Mazur, Jakub Szarłowicz, Zofia Goliszek, Karolina Łucja Sobek, Wiktoria Tabin-Barczak, Aldona Sokołowska, Klaudia Fikas, Kamil Chwaliszewski, Sebastian Samuła

“…Introduction and Purpose: Adalimumab, a TNF-α inhibitor, is a cornerstone treatment for autoimmune and inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. …”
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Effects of different doses of glucose and fructose on central metabolic pathways and intercellular wireless communication networks in humans by Dingqiang Lu, Yujiao Liu, Miao Zhao, Shuai Yuan, Danyang Liu, Xinqian Wang, Yixuan Liu, Yifei Zhang, Ming Li, Yufeng Lü, Guangchang Pang, Ruijuan Ren

“…Therefore, excessive intake of fructose should be reduced to avoid excessive inflammatory responses, allergic reactions and autoimmune diseases.…”
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