Immune modulation effects of curcumin in pristane-induced lupus mice by Handono Kalim, Kusworini Handono, Takhta Khalasha, Mirza Zaka Pratama, Tri Wahyudi Iman Dantara, Ayu Pramitha Wulandari, Fahimma Albinsaid, Sofi Nur Fitria, Muhammad Vardian Mahardika

“…Meanwhile, intraperitoneal (i.p.) injection of the hydrocarbon oil pristane into normal mice leads to a lupus-like autoimmune syndrome. We aimed to investigate the effects of curcumin on systemic lupus erythematosus (SLE) clinical manifestation, adaptive immune system components, proinflammatory cytokines, and autoantibody production in pristane-induced lupus mice. …”
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Comparison of mNGS with conventional methods for diagnosis of cryptococcal meningitis: a retrospective study by Zai-Jie Jiang, Jian-Chen Hong, Bi-Wei Lin, Wei-Qing Zhang, Qi-Chao Fan, Bi-Hui Yang, Xiang-Ping Yao

“…Patients with bacterial tuberculous or viral meningitis were used as mNGS-positive controls and one autoimmune encephalitis patient was used as an mNGS-negative control. …”
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Healthcare Utilization and Costs Among US Adolescents With Alopecia Areata by Markqayne Ray, Elyse Swallow, Kavita Gandhi, Christopher Carley, Vanja Sikirica, Travis Wang, Nicolae Done, James Signorovitch, Arash Mostaghimi

“…**Background:** Alopecia areata (AA) is an autoimmune disease of hair loss affecting people of all ages. …”
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Identification of a pathogenic founder variant in the WFS1 gene that causes Wolfram syndrome in the Druze population by Inbal Halabi, Inbal Halabi, Yardena Tenenbaum-Rakover, Yardena Tenenbaum-Rakover, Lena Sagi-Dain, Lena Sagi-Dain, Lena Sagi-Dain, Ilana Koren, Ilana Koren, Ilana Koren

“…The identified variant should be considered for genetic testing in individuals of Druze ancestry diagnosed with young-onset non-autoimmune diabetes. Early diagnosis of WS is important for therapeutic approaches, especially since novel medications are becoming available.…”
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Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome: Focusing on inflammation and molecular mechanisms by Mohammad Yasin Zamanian, Hamidreza Zafari, Maria K. Osminina, Alla A. Skakodub, Raed Fanoukh Aboqader Al‐Aouadi, Maryam Golmohammadi, Nikta Nikbakht, Iman Fatemi

“…Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects approximately 0.46% of the global population. …”
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Serum calprotectin and renal function decline in ANCA-associated vasculitides: a post hoc analysis of MAINRITSAN trial by Xavier Romand, Benjamin Terrier, Athan Baillet, Philippe Gaudin, Loic Guillevin, Christian Pagnoux, Minh Vu Chuong, Marie Hélène Paclet

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Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals by Eleuza Rodrigues Machado, Núbia Oliveira Matos, Sinione Morais Rezende, Daniela Carlos, Thauana Cristina Silva, Leônia Rodrigues, Maria Jarlene Rodrigues Almeida, Maria Regina Fernandes de Oliveira, Maria Imaculada Muniz-Junqueira, Rodrigo Gurgel-Gonçalves

“…The lower frequency of A. lumbricoides found in type 1 diabetes may be related to a strong Th2 response to parasites. Autoimmune response developed in type 1 diabetic individuals characterized by the production of Th1 cytokines could explain low frequency of G. lamblia. …”
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Inflammatory Biomarkers and Lipid Parameters May Predict an Increased Risk for Atrial Arrhythmias in Patients with Systemic Sclerosis by Veronika Sebestyén, Dóra Ujvárosy, Balázs Ratku, Hajnalka Lőrincz, Sára Csiha, Dóra Tari, Gyöngyike Majai, Sándor Somodi, Gabriella Szűcs, Mariann Harangi, Zoltán Szabó

“…Background/Objectives: Autoimmune inflammation enhances the electrical instability of the atrial myocardium in patients with systemic sclerosis (SSc); thus, atrial arrhythmia risk is increased, which might be predicted by evaluating the P wave interval and dispersion of a 12-lead surface electrocardiogram (ECG). …”
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Diagnostic delay of myositis: protocol for an integrated systematic review by Christine Phillips, Matthew Cook, Anne Parkinson, Jane Desborough, Tergel Namsrai, Anita Chalmers, Christine Lowe

“…Introduction Idiopathic inflammatory myopathies (IIM). described as ‘inflammatory myositis’, are a heterogeneous group of rare muscular autoimmune diseases characterised by skeletal muscle inflammation. …”
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Immunological Aspects of Fulminant Type 1 Diabetes in Chinese by Zhen Wang, Ying Zheng, Yiting Tu, Zhijie Dai, Jian Lin, Zhiguang Zhou

“…We also detected a significant increase for IFN-γ expression in FT1D PBMCs as compared with that of healthy controls. Conclusion. Autoimmune responses might be involved in the pathogenesis of Chinese FT1D.…”
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Analysis of the Expression and Function of Immunoglobulin-Like Transcript 4 (ILT4, LILRB2) in Dendritic Cells from Patients with Systemic Lupus Erythematosus by Paola del Carmen Guerra-de Blas, Yael Sebastián Villaseñor-Talavera, Daniela de Jesús Cruz-González, Lourdes Baranda, Lesly Doníz-Padilla, Carlos Abud-Mendoza, Roberto González-Amaro, Adriana Elizabeth Monsiváis-Urenda

“…ILT4 was shown not to have a crucial role in regulating the maturation and function of DC from healthy controls but is partially involved in the maturation process and immunogenic capability of DC from SLE patients, suggesting that other inhibitory receptors, involved in the regulation of DC tolerogenic function, may be impaired in this autoimmune disease.…”
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The Role of Pyroptosis‐Related Gene Signature and Immune Infiltration in Juvenile Dermatomyositis by Qiao W, Zhu C, Huang D, Liu Y, Wang Z, Zhu T, Song Q, Yang X, Wang Y, Wang Y

“…Weizhou Qiao,1,* Cuiping Zhu,2,* Dan Huang,1 Yue Liu,1 Zengkai Wang,1 Tianjie Zhu,1 Qingyu Song,1 Xu Yang,1 Yueying Wang,1 Yushuang Wang1 1Department of Clinical Laboratory, Central Hospital of Dalian University of Technology, Dalian, 116033, People’s Republic of China; 2Blood Purification Center, Central Hospital of Dalian University of Technology, Dalian, 116033, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weizhou Qiao, Department of Clinical Laboratory, Central Hospital of Dalian University of Technology, No. 826, Southwest Road, Shahekou District, Dalian, Liaoning, 116033, People’s Republic of China, Email qiaoweizhou2024@163.comObjective: Juvenile dermatomyositis (JDM) is a complex autoimmune disease, and its pathogenesis remains poorly understood. …”
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Butyric Acid Modulates Gut Microbiota to Alleviate Inflammation and Secondary Bone Loss in Ankylosing Spondylitis by Ke You, Lianjun Yang, Zhihai Su, Jun Shen, Xinyang Fan, Yuanqing Guo, Zhen Yuan, Hai Lu

“…<b>Background:</b> Ankylosing spondylitis (AS) is a chronic inflammatory and autoimmune disease that primarily affects the sacroiliac joints and axial skeleton. …”
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Multi-disciplinary treatment of broncho-esophageal fistula in a high-risk single-lung patient by Rune Haaverstad, Kjell Ovrebo, Lorentz Sandvik, Håvard Seland, Gunnar Reksten Husebø, Vegard Skalstad Ellensen, Marit Farstad, Eivind Strandenes, Rajinder Sharma, Marianne Øksnes, Anders Kjellevold Storesund, Solveig Moss Kolseth

“…Case presentation BEF presented in a 40-year-old female patient 8 years after curative treatment with pneumonectomy and radio-chemotherapy for advanced lung cancer. She had autoimmune comorbidity, a single lung, vocal cord paralysis and an extremely hostile thorax. …”
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Severe Guillain-Barré syndrome with concurrent optic neuritis in a pediatric patient: a case report by Xin Xue, Yingcun Bao, Yakun Yu, Qun Li, Mei Liu, Xiaoling Li

“…It also underscores the need for awareness of overlapping central and peripheral autoimmune neuropathies to improve diagnostic accuracy and patient outcomes.…”
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Feature selection enhances peptide binding predictions for TCR-specific interactions by Hamid Teimouri, Hamid Teimouri, Zahra S. Ghoreyshi, Zahra S. Ghoreyshi, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Jason T. George, Jason T. George, Jason T. George, Jason T. George

“…Accurate prediction of peptide binding to TCRs is essential for advancing immunotherapy, vaccine design, and understanding mechanisms of autoimmune disorders.MethodsThis study presents a theoretical approach that explores the impact of feature selection techniques on enhancing the predictive accuracy of peptide binding models tailored for specific TCRs. …”
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Resistance Exercise Reduces Skeletal Muscle Cachexia and Improves Muscle Function in Rheumatoid Arthritis by Salaheddin Sharif, James M. Thomas, David A. Donley, Diana L. Gilleland, Daniel E. Bonner, Jean L. McCrory, W. Guyton Hornsby, Hua Zhao, Mathew W. Lively, Jo Ann A. Hornsby, Stephen E. Alway

“…Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune, inflammatory disease associated with cachexia (reduced muscle and increased fat). …”
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Sjögren’s Syndrome: Concerted Triggering of Sicca Conditions by Zygmunt Mackiewicz, Justyna Mażul, Ieva Narkevičiūtė, Irena Dumalakienė, Irena Butrimienė, Rita Vilienė, Indrė Stankevičienė, Diana Mieliauskaitė

“…The aim of this study was to evaluate the expression of persistence of mumps virus and some cells that interact with viral infection in the focus of the autoimmune epithelitis and peripheral blood of Sjögren’s syndrome patients in comparison to patients with rheumatoid arthritis (RA) and nonautoimmune sicca syndrome (nSS). …”
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Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model by Akiko Nishidate, Kana Takemoto, Yuki Imura, Mikako Murase, Ryu Yamanaka, Manami Kikuchi, Junpei Anan, Sayuka Kato, Airi Akatsuka, Sachiko Mochizuki, Yuzo Koda

“…Abstract Idiopathic inflammatory myopathies (IIMs) are a group of autoimmune disorders characterized by immune cell infiltration of muscle tissue accompanied by inflammation. …”
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Real-world clinical experience with secukinumab in psoriatic arthritis: an observational study and a literature review by Eleonora Celletti, Giulio Gualdi, Emanuela Sabatini, Francesco Cipollone, Fabio Lobefaro, Paolo Amerio

“…The major comorbidities recorded were fibromyalgia (33% of patients), recurrent bilateral anterior uveitis, and autoimmune thyroiditis with hypothyroidism (both 13% of the patients). …”
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