Myeloid Disease with the CSF3R T618I Mutation after CLL by Maria Eduarda Couto, Susana Bizarro, Domingos Sousa, Nelson Domingues, Isabel Oliveira, Gabriela Martins, Manuel R. Teixeira, Mário Mariz

“…He remained in surveillance and suffered 2 episodes of autoimmune hemolytic anemia until 2019. Then, the hemolytic anemia relapsed and a neutrophilia became evident (progressing slowly), as well as a thrombocytopenia and splenomegaly without adenopathy were found. …”
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Elevated Troponin Serum Levels in Adult Onset Still’s Disease by Carlo Umberto Manzini, Lucio Brugioni, Michele Colaci, Maurizio Tognetti, Amelia Spinella, Marco Sebastiani, Dilia Giuggioli, Clodoveo Ferri

“…Diagnosis is based on typical AOSD symptoms after the exclusion of well-known infectious, neoplastic, or autoimmune/autoinflammatory disorders. In the case of abrupt, recent onset AOSD, it could be particularly difficult to make the differential diagnosis and in particular to early detect the possible heart involvement. …”
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Effects of Maillard reaction and its product AGEs on aging and age-related diseases by Huan Peng, Yuqi Gao, Chenye Zeng, Rui Hua, Yannan Guo, Yida Wang, Zhao Wang

“…On the other hand, pathological aging associated with autoimmune and inflammatory diseases, neurodegenerative diseases, diabetes and diabetic nephropathy, cardiovascular diseases and bone degenerative diseases have been mainly proposed. …”
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The Prognostic Value of Total Blood Count Parameter Ratios in Acute Pulmonary Embolism by Aynur Yurtseven, Kerem Ensarioğlu

“…Exclusion criteria included recent infection, autoimmune diseases, or immunosuppressive therapy. Laboratory data, clinical parameters, and outcomes (e.g., hospitalization duration, complications, and mortality) were analyzed. …”
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Vascular Endothelial Growth Factor in Tear Samples of Patients with Systemic Sclerosis by Anikó Rentka, Jolán Hársfalvi, András Berta, Krisztina Köröskényi, Zoltán Szekanecz, Gabriella Szücs, Peter Szodoray, Ádám Kemény-Beke

“…Systemic sclerosis is an autoimmune disease, characterized by widespread small vessel vasculopathy, immune dysregulation with production of autoantibodies, and progressive fibrosis. …”
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Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair by Zongquan Zhang, Guan Wang, Zhuo Zhang, Xiaoya Liang, Guoshuang Wang, Maochang Xu, Xi Yang, Xiaolin Zhong, Chunhong Li, Meiling Zhou

“…Abstract Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by synovial hyperplasia, where inflammatory macrophages within the joint synovium produce multiple inflammatory cytokines, leading to cartilage damage. …”
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Detection and Analysis of Autoantigens Targeted by Autoantibodies in Immunorelated Pancytopenia by Hui Liu, Rong Fu, Yihao Wang, Hong Liu, Lijuan Li, Honglei Wang, Jin Chen, Hong Yu, Zonghong Shao

“…Autoantibody IgG was detected in the BM supernatant of 75% of patients (15/20), which was significantly higher than that in aplastic anemia, myelodysplastic syndrome, or autoimmune hemolytic anemia patients (0%) and normal healthy controls (0%) (P<0.01). …”
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Mast Cell-Mediated Inhibition of Abdominal Neutrophil Inflammation by a PEGylated TLR7 Ligand by Tomoko Hayashi, Shiyin Yao, Brian Crain, Michael Chan, Howard B. Cottam, Fitzgerald Lao, Dennis A. Carson, Maripat Corr

“…To abate the deleterious recruitment of neutrophils in sterile inflammation, we repeatedly administered a TLR7 ligand that hyposensitized to TLR7 and receptors that converged on the MyD88-signaling intermediary and reduced cellular infiltration in murine autoimmune models of multiple sclerosis and arthritis. …”
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Tetracyclines in Rheumatoid Arthritis: Dual Anti-Inflammatory and Immunomodulatory Roles, Effectiveness, and Safety Insights by Mislav Radić, Andrej Belančić, Hana Đogaš, Marijana Vučković, Andrea Gelemanović, Andrea Faour, Ivan Vlak, Josipa Radić

“…Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent inflammation, joint pain, and progressive cartilage and bone erosion. …”
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Histologic evidence of neutrophil extracellular traps and fibrin(ogen) deposition in liver biopsies from patients with inflammatory liver disease by Fien A. von Meijenfeldt, Ton Lisman, Alessandra Pacheco, Yoh Zen, William Bernal

“…Methods: Liver biopsies from patients with inflammatory liver disease (alcoholic steatohepatitis [ASH], autoimmune hepatitis, primary sclerosing cholangitis, metabolic-associated steatohepatitis, and allograft ischemia-reperfusion injury (IRI), each n = 20) were stained for fibrin(ogen), platelets, and NETs. …”
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Analytical validation of a novel bioassay for thyroid-stimulating immunoglobulin by Paul D. Olivo, Hannah Kim, Lynn Miao, Jeffery A. Houtz, George J. Kahaly

“…The Turbo TSI bioassay demonstrated 95.2% (95% CI 83.3-98.1) positive percent agreement and 94.8% (95% CI 90.9-97.1) negative percent agreement with an FDA-cleared bioassay (Thyretain® TSI) using serum from 295 patients with autoimmune thyroid disease.ConclusionsThe Turbo TSI bioassay exhibits excellent analytical performance and a high level of reproducibility. …”
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Pharmacological Inhibition of Glutaminase 1 Normalized the Metabolic State and CD4+ T Cell Response in Sjogren’s Syndrome by Jiayao Fu, Yiping Pu, Baoli Wang, Hui Li, Xiujuan Yang, Lisong Xie, Huan Shi, Zhijun Wang, Junhao Yin, Tianle Zhan, Yanxiong Shao, Changyu Chen, Qi Luo, Jiabao Xu, Zirui Zong, Xindi Wei, Wanwen Xiao, Chuangqi Yu, Lingyan Zheng

“…Previous studies have shown that abnormal metabolic reprogramming in CD4+ T cells could explain the occurrence of several autoimmune disorders, including Sjogren’s syndrome (SS). …”
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Review of Current First-Line Pharmacotherapy Strategies for Thyroid Eye Disease by Julia Ryniecka, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Kulbacka, Michalina Wójcikiewicz, Marta Chuncia-Ileczko, Julia Kacperczyk, Filip Arczewski, Karol Dziedzic

“… Thyroid eye disease (TED) is a challenging autoimmune disorder that often requires therapeutic intervention. …”
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Comparisons of Differentiation Potential in Human Mesenchymal Stem Cells from Wharton’s Jelly, Bone Marrow, and Pancreatic Tissues by Shih-Yi Kao, Jia-Fwu Shyu, Hwai-Shi Wang, Chi-Hung Lin, Cheng-Hsi Su, Tien-Hua Chen, Zen-Chung Weng, Pei-Jiun Tsai

“…Type 1 diabetes mellitus results from autoimmune destruction of β-cells. Insulin-producing cells (IPCs) differentiated from mesenchymal stem cells (MSCs) in human tissues decrease blood glucose levels and improve survival in diabetic rats. …”
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Evaluation of Tele-rheumatology during the COVID-19 Pandemic in Asian Population: A Pilot Study by Amit Sandhu, Amit Agarwal, Paramvir Kaur, Meenakshi Sharma, Harnoor Sra, Manvi Singh, Nishant Jaiswal, Anil Chauhan, Anju Gupta, Meenu Singh

“…Rheumatoid arthritis (RA) is a chronic autoimmune condition associated with a potential for deformities. …”
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Genetic screening strategy for children with hereditary spherocytosis in Jiangxi Province of China by Chongjun Wu, Chongjun Wu, Zhongjin Xu, Zhongjin Xu, Qian Wan, Qian Wan, Feng Chen, Feng Chen, Yao Ye, Yao Ye, Hong Wang, Hong Wang

“…Upon initial diagnosis, the clinical features of HS were not significantly distinct compared to other forms of anemia.ConclusionIn Jiangxi, China, our strategy of genetic screening for these children is feasible after excluding the common causes of anemia, such as nutritional anemia, G-6-PD deficiency, thalassemia, autoimmune hemolytic anemia, and myelopoietic abnormalities in children. …”
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Anti-Osteoporosis Is Imperative in Prevention of Progress of Ankylosing Spondylitis by Zheng B, Yu P, Liu H, Liang Y

“…Bin Zheng,&ast; Panfeng Yu,&ast; Haiying Liu, Yan Liang Spine Surgery, Peking University People’s Hospital, Beijing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yan Liang, Email liangyan_spine@163.comBackground: Ankylosing spondylitis (AS) is a chronic autoimmune disease that affects the spine and peripheral joints, often leading to kyphosis, joint stiffness, and even ankylosis. …”
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COVID-19 encephalopathy with severe neurological symptoms: a clinical case presentation with literature review by G. Baranauskienė, N. Tutlienė, G. Kaubrys

“…However, the most likely etiology of encephalopathy is multifactorial: systemic disease response, inflammation, coagulopathy, direct viral neuroinvasion, endoartheritis, and possibly post-infectious autoimmune mechanisms. For patients with suspected changes in the level of consciousness due to coronavirus infection, it is recommended to perform a thorough examination of the cerebrospinal fluid (CSF), head imaging with a preference for magnetic resonance imaging (MRI), and electroencephalography (EEG) It is worth noting that blood or imaging tests often do not show specific changes in patients with encephalopathy. …”
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Systemic Lupus Erythematosus Presenting as Anorexia Nervosa in a Middle‐Aged Woman: A Rare Case Report and Literature Review by Maen Nizam Baroudi, Anwar I. Joudeh, Mohammed Kays Alattiya, Abdo Qaid Ahmed Lutf, Hassan Abuzaid, Salah Mahdi

“…ABSTRACT Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystemic involvement and unclear etiology. …”
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Combined Treatment with Antiviral Therapy and Rituximab in Patients with Mixed Cryoglobulinemia: Review of the Literature and Report of a Case Using Direct Antiviral Agents-Based A... by Teresa Urraro, Laura Gragnani, Alessia Piluso, Alessio Fabbrizzi, Monica Monti, Elisa Fognani, Barbara Boldrini, Jessica Ranieri, Anna Linda Zignego

“…Mixed cryoglobulinemia (MC) is an autoimmune/B-cell lymphoproliferative disorder associated with Hepatitis C Virus (HCV) infection, manifesting as a systemic vasculitis. …”
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