Polydeoxyribonucleotide Dermal Infiltration in Male Genital Lichen Sclerosus: Adjuvant Effects during Topical Therapy by Luigi Laino, Silvia Suetti, Isabella Sperduti

“…Lichen sclerosus (LS) is an autoimmune inflammatory skin disease that leads to tissue sclerosis. …”
Get full text

Mathematical insights on psoriasis regulation: Role of Th1 and Th2 cells by Amit Kumar Roy, Priti Kumar Roy, Ellina Grigorieva

“…Psoriasis is an autoimmune disorder, characterized by hyper-proli-feration of Keratinocytes for the abnormal activation of T Cells, Dendritic Cells (DCs) and cytokine signaling. …”
Get full text

Methadone-Induced Delayed Posthypoxic Encephalopathy: Clinical, Radiological, and Pathological Findings by Manoj Mittal, Yunxia Wang, Alan Reeves, Kathy Newell

“…Extensive work up was negative for any metabolic, infectious or autoimmune disorder. Brain biopsy showed significant axonal injury in the white matter. …”
Get full text

Modulatory Function of Invariant Natural Killer T Cells in Systemic Lupus Erythematosus by Yi-Ping Chuang, Chih-Hung Wang, Ning-Chi Wang, Deh-Ming Chang, Huey-Kang Sytwu

“…Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease with complex immunological and clinical manifestations. …”
Get full text

Successful case of using suture-mediated system Perclose ProGlide in TAVI by B. M. Todurov, M. B. Todurov, A. V. Khokhlov, M. V. Stan, K. L. Berestova, O. V. Zelenchuk, A. V. Besaga, S. R. Maruniak

“…This clinical case describes the performance of TAVI in a patient with liver cirrhosis, autoimmune hepatitis, coagulopathy, and secondary anemia. …”
Get full text

Case report: Primary cardiac synovial sarcoma with suspected connective tissue disease diagnosed by EBUS-TBMB by Yanmei Feng, Chunxia Wu, Jing Chi, Linying Li, Pu Wang, Rui Guo

“…Although biomarkers of autoimmune diseases, such as antinuclear antibodies (ANAs), have been reported as potential indicators of certain tumors, the association between PCSS and ANAs remains unclear. …”
Get full text

Shifting the paradigm of type 1 diabetes: a narrative review of disease-modifying therapies by Alexander J. O’Donovan, Seth Gorelik, Seth Gorelik, Laura M. Nally

“…A new diagnosis of type 1 diabetes (T1D) may be accompanied by numerous lifelong financial, emotional, and physical challenges, thus advancements in therapies that can delay the onset of clinical disease are crucial. T1D is an autoimmune condition involving destruction of pancreatic beta cells leading to insulin deficiency, hyperglycemia, and long-term insulin dependence. …”
Get full text

Hashimoto’s Encephalopathy Presenting with Unusual Behavioural Disturbances in an Adolescent Girl by Murugan Selvaraj Karthik, Kulothungan Nandhini, Viswanath Subashini, Ramasamy Balakrishnan

“…Hashimoto’s encephalopathy (HE) is a rare autoimmune disorder with neurological and neuropsychiatric manifestations and elevated titres of anti-thyroid antibodies. …”
Get full text

Bioinformatic analysis of ferroptosis related biomarkers and potential therapeutic targets in vitiligo by Linli Liu, Lingli Deng, Li Guan, Yuan Hu, Qianying Li, Chunshui Yu

“…Abstract Vitiligo is a complex autoimmune skin disorder characterized by depigmentation and immune dysregulation. …”
Get full text

Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women by Leonie Fleige, Silvia Capellino

“…Another contributing factor appears to be sex, as sex-specific differences in the dopaminergic pathway are described in the neurological context as well as in autoimmune diseases. However, a deeper understanding of these differences in peripheral immune cells remains limited. …”
Get full text

Mannose-binding lectin gene sequence data in Kelantan population by Muhamad Aidil Zahidin, Noor Haslina Mohd Noor, Muhammad Farid Johan, Abu Dzarr Abdullah, Zefarina Zulkafli, Hisham Atan Edinur

“…Human MBL deficiency is associated with immunodeficiencies, and its variants have been linked to autoimmune and infectious diseases. Despite this significance, gene studies concerning MBL sequencing are uncommon in Malaysia. …”
Get full text

Characteristics of primary biliary cirrhosis in British Columbia's First Nations population by Laura Arbour, Rosemarie Rupps, Leigh Field, Paul Ross, Anders Erikson, Harvey Henderson, Warren Hill, Eric M Yoshida

“…Primary biliary cirrhosis (PBC) is a rare, autoimmune liver disorder characterized by progressive destruction of intrahepatic bile ducts, that results in portal inflammation, scarring, cirrhosis and, eventually, liver failure. …”
Get full text

Chylous Ascites and Pleural Transudate: Rare Presentations in Systemic Lupus Erythematosus in Old Age by Guan-Liang Chen, Deng-Ho Yang, Wen-Hsiu Hsu

“…Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder with involvement of multiple organs. …”
Get full text

Resolution of Crizotinib-Associated Fulminant Hepatitis following Cessation of Treatment by Gregory W. Charville, Sukhmani K. Padda, Richard K. Sibley, Ajithkumar Puthillath, Paul Y. Kwo

“…There was no evidence of an infectious or autoimmune etiology. It was discovered that the patient was taking a 500 mg once daily dose of crizotinib, in lieu of the intended dose of 250 mg twice daily. …”
Get full text

Case report: Scleromalacia caused by rheumatoid arthritis combined with high intraocular pressure, first discovered due to ocular trauma by Yanyan Zhang, Yanyan Wang, Ruihao Xu, Tianyu Wang, Yuhao Zhang, Jinghai Mao, Quanyong Yi

“…This case once again underscores the importance of clinicians paying close attention to the impact of systemic autoimmune diseases on ocular health.…”
Get full text

PBC: Animal Models of Cholangiopathies and Possible Endogenous Viral Infections by Masashi Ninomiya, Yoshiyuki Ueno, Tooru Shimosegawa

“…Primary Biliary Cirrhosis (PBC) is considered an autoimmune disease characterized by immune-mediated destruction of the intrahepatic bile ducts and its characteristic serologic marker, the anti-mitochondrial antibody (AMA). …”
Get full text

CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct t... by Mercedes Zubiaur, Laura C. Terrón-Camero, Fernando Gordillo-González, Eduardo Andrés-León, Alicia Barroso-del Jesús, Luz María Canet-Antequera, María M. Pérez Sánchez-Cañete, África Martínez-Blanco, Marilú Domínguez-Pantoja, María Botia-Sánchez, Sonia Pérez-Cabrera, Nerea Bello-Iglesias, Antonio Alcina, Ana-Clara Abadía-Molina, Fuencisla Matesanz, Esther Zumaquero, Ramón Merino, Jaime Sancho

“…This study aimed to elucidate the transcriptomic signatures and dysregulated pathways associated with the autoimmune response in Cd38-/- mice compared to wild-type (WT) mice within the bm12 chronic graft-versus-host disease (cGVHD) lupus model. …”
Get full text

Identification of strengths and weaknesses of the healthcare system for persons living with rare diseases in Catalonia (Spain), and recommendations to improve its comprehensive att... by José Hernández-Rodríguez, Fernando Martínez-Valle, Xènia Acebes, Carmen Alerany, Jordi Antón, Gonzalo Calvo, Marian Corral, Jordi Cruz, M. Antònia Mangues-Bafalluy, José Mateo, Josefa Rivera, Albert Salazar, Roser Francisco, Cristina Mallol, Rita Reig-Viader, Ariadna Tigri-Santiña, Assumpta Ricart, Francesc Palau

Get full text

Results from Ad Hoc and Routinely Collected Data among Celiac Women with Infertility or Pregnancy Related Disorders: Italy, 2001–2011 by Francesca Fortunato, Domenico Martinelli, Rosa Prato, Biagio Pedalino

“…Celiac disease (CD) is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals. …”
Get full text

Association of Autoantibodies to BP180 with Disease Activity in Greek Patients with Bullous Pemphigoid by Aikaterini Patsatsi, Aikaterini Kyriakou, Aikaterini Pavlitou-Tsiontsi, Anastasia Giannakou, Dimitrios Sotiriadis

“…39 bullous pemphigoid (BP) patients were studied to assess the clinical significance of anti-BP180 and anti-BP230 circulating autoantibodies of BP and correlate their titers with the clinical scores of the BP Disease Area Index (BPDAI) and the Autoimmune Bullous Skin Disorder Intensity Score (ABSIS) as well as with the intensity of pruritus measured by the BPDAI pruritus component. …”
Get full text