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Isolated Pauci-Immune Pulmonary Capillaritis Associated with Hydrocarbon Inhalation and Marijuana Smoking: An Unusual Case of Severe Hypoxemia
Published 2020-01-01“…His laboratory evaluation initially showed microscopic hematuria which later cleared, but other tests including serologic autoimmune assessment were negative, and he did not have any traditional risk factors for vasculitis. …”
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1202
Role of Inflammasomes in Neuroimmune and Neurodegenerative Diseases: A Systematic Review
Published 2018-01-01“…Several components of inflammasomes, such as nucleotide-binding oligomerization domain- (NOD-) like receptor, absent in melanoma 2- (AIM2-) like receptors (ALRs), apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), and caspase-1, as well as the upstream factors and downstream effectors, are associated with the initiation and development of MS and its animal model, experimental autoimmune encephalomyelitis. Additionally, inflammasomes affect the efficacy of interferon-β therapy in patients with MS. …”
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1203
Toll-Like Receptor Signaling and Liver Fibrosis
Published 2010-01-01“…Liver fibrosis occurs as a wound-healing scar response following acute and chronic liver inflammation including alcoholic liver disease, non-alcoholic steatohepatitis, hepatitis B and C, and autoimmune hepatitis. Myofibroblasts, mainly transdifferentiated from hepatic stellate cells, are pivotal cell types that produce fibrillar collagen. …”
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1204
Rheumatoid Arthritis Effects on Kidney and Liver and their Correlations with CDAI
Published 2022-11-01“… Rheumatoid arthritis (RA) is a disease characterized by chronic autoimmune inflammation of body joints, causing movement disability, loss of functions, joint damage, and many complications. …”
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1205
New treatment options for generalized myasthenia gravis
Published 2024-02-01“…Myasthenia gravis is an autoimmune disease in which autoantibodies against the postsynaptic membrane proteins of the neuromuscular junction disrupt impulse transmission thus causing pathological muscle weakness and fatigue that worsens throughout the day. …”
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1206
Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells
Published 2016-01-01“…Type 1 diabetes is an autoimmune disease resulting in the permanent destruction of pancreatic islets. …”
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1207
Chronic Gastritis in Dermatitis Herpetiformis: A Controlled Study
Published 2012-01-01“…H. pylori will partly explain this, but corpus atrophy is suggestive of an autoimmune etiology. Atrophic gastritis may increase the risk of gastric cancer. …”
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1208
Enhancing Mesenchymal Stromal Cell Immunomodulation for Treating Conditions Influenced by the Immune System
Published 2019-01-01“…Thus, immunosuppressive treatment with MSCs has been proposed as a potential therapeutic alternative for conditions in which the immune system cells influence outcomes, such as inflammatory and autoimmune diseases. The precise mechanism by which MSCs affect functions of most immune effector cells is not completely understood but involves direct contact with immune cells, soluble mediators, and local microenvironmental factors. …”
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1209
Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report
Published 2024-10-01“…Rare, non-compressive causes of chiasmopathy include, among others, infectious, post-infectious, inflammatory, autoimmune, demyelinating, toxic and ischaemic processes. …”
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1210
Modern methods of studying of human gastro-intestinal microflora
Published 2014-08-01“…New data on relation of disorders of microflora with diseases of cardio-vascular system, disorders of metabolism, autoimmune and allergic diseases have appeared. From the middle of XX century bacteriological method of investigation based on obtaining of pure culture was widely applied in rating of microflora pattern. …”
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1211
Manifestaciones bucales de la enfermedad celíaca en pacientes geriátricos consumidores de gluten
Published 2024-09-01“…<p><strong>Foundation</strong>: Celiac disease is a chronic inflammatory and autoimmune disease that affects genetically susceptible individuals due to a permanent intolerance to gluten. …”
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1212
Graves’ ophthalmopathy: the clinical and psychosocial outcomes of different medical interventions – a systematic review
Published 2024-05-01“…Background Graves’ ophthalmopathy is a complex autoimmune disorder that can significantly affect quality of life (QoL), vision and physical appearance. …”
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1213
What Do Gases in the Large Intestine Have to Do with Health?
Published 2025-02-01“…Celiac disease, an autoimmune condition, causes damage to intestinal villi, impairing digestion and absorption. …”
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1214
J-TAIL-2: A Prospective, Observational Study of Atezolizumab Combined With Carboplatin and Etoposide in Patients With Extensive-Stage SCLC in Japan
Published 2025-03-01“…., Eastern Cooperative Oncology Group performance status 2 or more, interstitial lung disease, autoimmune disease) versus IMpower133-like groups. Results: Overall, 403 patients were included; the median age was 71 years, 16.6% (n = 67) had an Eastern Cooperative Oncology Group performance status 2 or more, 26.8% (n = 108) had brain metastasis, 6.9% (n = 28) had interstitial lung disease, 4.0% (n = 16) had autoimmune disease, and 72.7% (n = 293) were IMpower133-unlike. …”
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1215
Methods of massive parallel reporter assays for investigation of enhancers
Published 2021-06-01“…Alterations of gene regulatory elements may cause various pathologies, including cancer, congenital disorders and autoimmune diseases. The development of high-throughput genomic assays has made it possible to significantly accelerate the accumulation of information about the characteristic epigenetic properties of regulatory elements. …”
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1216
Integrative genetics and multiomics analysis reveal mechanisms and therapeutic targets in vitiligo highlighting JAK STAT pathway regulation of CTSS
Published 2025-01-01“…Abstract Vitiligo is a complex autoimmune disease characterized by the loss of melanocytes, leading to skin depigmentation. …”
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1217
The Composition of Gut Microbiota in Patients Bearing Hashimoto’s Thyroiditis with Euthyroidism and Hypothyroidism
Published 2020-01-01“…Hashimoto’s thyroiditis (HT), a type of autoimmune disease, occurs due to genetic predisposition and environmental factors. …”
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1218
Morphologic Features of Extrahepatic Manifestations of Hepatitis C Virus Infection
Published 2012-01-01“…Other HCV-associated entities include porphyria cutanea tarda, lichen planus, necrolytic acral erythema, membranous glomerulonephritis, diabetic nephropathy, B-cell non-Hodgkin lymphomas, insulin resistance, sialadenitis, sicca syndrome, and autoimmune thyroiditis. This paper highlights the histomorphologic features of these processes, which are typically characterized by chronic inflammation, immune complex deposition, and immunoproliferative disease in the affected organ.…”
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1219
Long-term antibody responses to COVAXIN and COVISHIELD vaccines in rheumatoid arthritis patients and healthy control population – A cross-sectional study
Published 2025-01-01“…Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation and damage in the joints. …”
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1220
Multidose Streptozotocin Induction of Diabetes in BALB/c Mice Induces a Dominant Oxidative Macrophage and a Conversion of TH1 to TH2 Phenotypes During Disease Progression
Published 2005-01-01“…The aim of this study is to investigate the redox status of peritoneal Mp and its cytokine profile during the development of autoimmune diabetes induced by multiple low-dose streptozotocin in BALB/c mice. …”
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