Successful Modified Therapy in a Patient with Probable Infection-Associated Hemophagocytic Lymphohistiocytosis by Carl L. Kay, Matthew J. Rendo, Paul Gonzales, Sead G. Beganovic, Magdalena Czader

“…In adults, HLH is typically a complication of infections, autoimmune diseases, and malignancies. While the disease is often fatal, classic management of HLH revolves around early diagnosis and initiation of protocolized therapy. …”
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An update on oral manifestations of systemic disorders in dogs and cats by Claire Dosenberry, Boaz Arzi, Carrie Palm, Natalia Vapniarsky, Maria Soltero-Rivera

“…A wide range of systemic ailments may lead to lesions in the oral cavity, including immune-mediated diseases, adverse drug reactions, viral and bacterial infections, and metabolic and autoimmune diseases. A complete history and thorough physical examination (including a fundic examination) should be obtained in affected patients. …”
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Single-Cell Transcriptome Analysis Profile of Meniscal Tissue Macrophages in Human Osteoarthritis by Jingbin Zhou, Zhihong Zhao, Chen He, Feng Gao, Yu Guo, Feng Qu, Yujie Liu

“…Unlike rheumatoid arthritis and other autoimmune diseases, inflammation in OA is chronic and, in relatively low grade, mainly mediated by the innate immune system, especially macrophages. …”
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Life-Threatening Intrapulmonary Hemorrhage due to Vancomycin-Induced Thrombocytopenia: A Case Report by Haneen Abdalhadi, Yazan Fahmawi, Abhijin Das, Brian Fouty

“…Workup was negative for thrombotic thrombocytopenic purpura, disseminated intravascular coagulopathy, atypical hemolytic uremic syndrome, heparin-induced thrombocytopenia, and autoimmune diseases. All recently started medications were discontinued, and the patient was started empirically on methylprednisolone and intravenous immunoglobulin. …”
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Promising Neutrophil-Associated Biomarkers in Lung Diseases of Patients with Antisynthetase Syndrome and Dermatomyositis by Lei Liu, Jundi Wang, Peiyu Zhang, Wenjia Sun, Xiuliang Zhu, Xiujuan Sun, Jing Xue, Huaxiang Wu

“…Antisynthetase syndrome (ASS) and dermatomyositis (DM) are serious autoimmune diseases, with lungs being the most frequently involved organ and sometimes fatal. …”
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Secukinumab-Induced Inflammatory Bowel Disease in a Patient Treated for Chronic Plaque Psoriasis and Psoriatic Arthritis: A Case Report and Review of the Role of Novel Biologic Age... by K. M. Darch, T. L. Holland, L. J. Spelman

“…Chronic plaque psoriasis and psoriatic arthritis are common autoimmune inflammatory conditions, often existing as comorbidities that have a significant impact on a patient’s quality of life. …”
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Hsp70 and Its Molecular Role in Nervous System Diseases by Giuseppina Turturici, Gabriella Sconzo, Fabiana Geraci

“…Hsp70 functions as a chaperone and protects neurons from protein aggregation and toxicity (Parkinson disease, Alzheimer disease, polyglutamine diseases, and amyotrophic lateral sclerosis), protects cells from apoptosis (Parkinson disease), is a stress marker (temporal lobe epilepsy), protects cells from inflammation (cerebral ischemic injury), has an adjuvant role in antigen presentation and is involved in the immune response in autoimmune disease (multiple sclerosis). The worldwide incidence of neurodegenerative diseases is high. …”
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Lupus Enteritis as an Initial Presentation of Systemic Lupus Erythematosus by Sisira Sran, Manpreet Sran, Narmisha Patel, Prachi Anand

“…Systemic lupus erythematosus (SLE) is an autoimmune disorder which can affect multiple organs and clinical presentation is often a myriad of symptoms; therefore, the index of suspicion should rise when evaluating patients with multiorgan symptomatology. …”
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Self-Management in Daily Life with Psoriasis: An Integrative Review of Patient Needs for Structured Education by Gitte Susanne Rasmussen, Helle Terkildsen Maindal, Kirsten Lomborg

“…As psoriasis increasingly gains recognition as a serious chronic autoimmune skin disease with long-term impairment on the life course, and not mainly a cosmetic problem, nurses are highly challenged to develop efficient education to support patient self-management. …”
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Neuropsychiatric Lupus and Lupus Nephritis Successfully Treated with Combined IVIG and Rituximab: An Alternative to Standard of Care by Mohamed M. Cheikh, Abdullah K. Bahakim, Moayad K. Aljabri, Saad M. Alharthi, Sanad M. Alharthi, Abdullah K. Alsaeedi, Saad F. Alqahtani

“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unpredictable course and flares. …”
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Embolic Stroke as the Initial Manifestation of Systemic Lupus Erythematosus by Reshma M. Khan, Rajaie Namas, Sachin Parikh, Bernard Rubin

“…She underwent transesophageal echocardiogram (TEE), which showed severe mitral regurgitation and thickening of mitral valve leaflets consistent with Libman-Sacks endocarditis. Autoimmune workup was positive for IF-ANA, anti-RNP, and anti-Smith antibody. …”
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Acute Kidney Injury, Recurrent Seizures, and Thrombocytopenia in a Young Patient with Lupus Nephritis: A Diagnostic Dilemma by Hector Alvarado Verduzco, Anjali Acharya

“…PRES has been associated with multiple conditions such as autoimmune disorders, pregnancy, organ transplant, and thrombotic microangiopathy (TMA). …”
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Performance of classification criteria for Behcet's disease in an Egyptian cohort by Mohamed Ahmed Hussein, Mona I Ellawindi, Gaafar Ragab

“…It included 256 patients classified as BD based on expert opinion and 205 patients with other autoimmune and/or autoinflammatory diseases with symptoms similar to BD. …”
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COVID-19-Induced Fatal Thrombotic Thrombocytopenic Purpura in a Healthy Young Patient by Mariana Codevila Buere Pereira, Bruna Ruschel, Bruna Schneider, Vitor Salomão Gonçalves Melo de Melgar, Tatiana Helena Rech

“…Since the global coronavirus disease 2019 (COVID-19) pandemic began, findings indicate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might induce autoimmune disorders. Thrombotic thrombocytopenic purpura (TTP) is a devastating disease if not emergently treated. …”
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Peripheral Ulcerative Keratitis with Pyoderma Gangrenosum by Adrián Imbernón-Moya, Elena Vargas-Laguna, Antonio Aguilar, Miguel Ángel Gallego, Claudia Vergara, María Fernanda Nistal

“…Its cause is still unknown although it is often associated with autoimmune conditions. Pyoderma gangrenosum should be included in the differential diagnosis of peripheral ulcerative keratitis. …”
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TRIM21-mediated PRMT1 degradation attenuates colorectal cancer malignant progression by Menghan Cao, Zhiying Shao, Xingyou Qian, Miaolei Chen, Chuyin Deng, Xintian Chen, Tingting Tang, Kaixu Zhang, Sufang Chu, Junnian Zheng, Jin Bai, Zhongwei Li

“…Abstract Tripartite motif-containing 21 (TRIM21) plays a crucial role in antiviral responses and autoimmune diseases. While the impact of TRIM21 on cancer has been studied in various tumors, its role in colorectal cancer (CRC) remains unclear. …”
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Particularities and management of late-onset rheumatoid arthritis by Enrique Martínez González, Liena Perdomo Roselló, Reiny Lorena Rosquete Ávila

“…Introduction: rheumatoid arthritis is an autoimmune disease with articular and extra-articular involvement. …”
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Two rare localizations of chondrosarcoma: cervical and thoracic spine by Sameh Sayhi, Maha Rebai, Ahmed Harbaoui, Sameh Achoura, Arij Ezzouhour Yahyaoui, Nadia Ben Abdelhafidh

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Case Report: Atypical post-COVID Cogan's syndrome [version 2; peer review: 2 approved] by Sayhi Sameh, Chaima Zitouni, Mayssa Bouzidi, Wafa Sleimi, Sameh Mezri

“…Background Cogan’s syndrome is a rare autoimmune disorder characterized by ocular inflammation, vestibulocochlear dysfunction, and systemic vasculitis. …”
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Outcome measurement in SLE patient: Indonesian version of RAND SF-36 summary scores and some scales were not reliable by Anggraini Kartika Sari Prita, Amelia Kharina, Cahyani Frameiza

“…Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can attack many organs with varying degrees of severity. …”
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