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1041
New T-lymphocyte subpopulations and their characteristics: Challenges to the classical division of lymphocyte function
Published 2024-11-01“…Furthermore, the discovery of CD20 + T cells challenges traditional views, offering new avenues for immunotherapy in cancer, autoimmune disorders, and infectious diseases. These findings expand our understanding of T-lymphocyte biology and suggest targets for more effective therapeutic interventions. …”
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1042
Correlates of Protection for M Protein-Based Vaccines against Group A Streptococcus
Published 2015-01-01“…Group A streptococcus (GAS) is known to cause a broad spectrum of illness, from pharyngitis and impetigo, to autoimmune sequelae such as rheumatic heart disease, and invasive diseases. …”
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1043
Immune Disorders in Hashimoto’s Thyroiditis: What Do We Know So Far?
Published 2015-01-01“…Recent research has demonstrated an increasing role of newly discovered cells such as Th17 (CD4+IL-17+) or T regulatory cells (CD4+CD25+highFoxP3+) in the induction of autoimmune disorders. The process of programmed cell death also plays an equally important role in the pathogenesis and the development of hypothyroidism.…”
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1044
Pure White Cell Aplasia and Necrotizing Myositis
Published 2016-01-01“…PWCA has been associated with autoimmune, drug-induced, and viral exposures. Here, we report a case of a 74-year-old female who presented with severe proximal weakness without pain and was found to have PWCA with nonspecific inflammatory necrotizing myositis and acute liver injury on biopsies. …”
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1045
Case Study: Chronic Recurrent Multifocal Osteomyelitis in the Femoral Diaphysis of a Young Female
Published 2012-01-01“…Instead it is more likely the result of genetic, autoimmune, or autoinflammatory causes. Although CRMO has a benign course and responds well to anti-inflammatory medications, it can have a very aggressive clinical and imaging presentation overlapping with infectious osteomyelitis and malignancy. …”
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1046
Two Patients with Therapy-Resistant Pemphigus Vulgaris and Severe Underlying Disease Showing Good Response to a New IVIg Preparation
Published 2025-01-01“…Abstract Pemphigus vulgaris is a severe and often therapy-resistant bullous autoimmune disease. Standard therapy with steroids often administered together with another immunosuppressant does not respond in all patients or may not be a good therapeutic option in patients with severe underlying diseases. …”
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1047
Pulmonary Alveolar Proteinosis in Setting of Inhaled Toxin Exposure and Chronic Substance Abuse
Published 2018-01-01“…PAP is categorized into three types: hereditary, autoimmune, and secondary. We report a case of secondary PAP in a 47-year-old man, whose risk factors include occupational exposure to inhaled toxins, especially aluminum dust, the use of anabolic steroids, and alcohol abuse, which in mice leads to alveolar macrophage dysfunction through a zinc-dependent mechanism that inhibits granulocyte macrophage-colony stimulating factor (GM-CSF) receptor signalling. …”
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1048
Understanding Muscle Dysfunction in Chronic Fatigue Syndrome
Published 2016-01-01“…Literature was examined following searches of PUB MED, MEDLINE, and Google Scholar, using key words such as CFS/ME, immune, autoimmune, mitochondria, muscle, and acidosis. Results. …”
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1049
Systemic Treatments for Noninfectious Vitreous Inflammation
Published 2013-01-01“…Vitreous inflammation, or vitritis, may result from many causes, including both infectious and noninfectious, including rheumatologic and autoimmune processes. Vitritis is commonly vision threatening and has serious sequelae. …”
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1050
Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR-γ Functional Module of Autophagy in Rheumatoid Arthritis
Published 2019-01-01“…Dysregulated autophagy leads to autoimmune diseases including rheumatoid arthritis (RA). …”
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1051
Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
Published 2021-01-01“…Erythema multiforme is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus, medications, autoimmune diseases, and malignancies, but the most common cause is infection by herpes simplex virus. …”
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1052
Successful Treatment of Hemophagocytic Lymphohistiocytosis Associated with Lupus Nephritis by Using Mycophenolate Mofetil
Published 2017-01-01“…HLH associated with autoimmune diseases is often refractory to corticosteroid treatment; thus, additional immunosuppressive drugs, such as cyclosporine, cyclophosphamide, or tacrolimus, are required. …”
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1053
Ferroptosis: A New Pathway in the Interaction between Gut Microbiota and Multiple Sclerosis
Published 2025-01-01“…Multiple sclerosis (MS) is a chronic autoimmune disorder marked by neuroinflammation, demyelination, and neuronal damage. …”
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1054
Emergency Splenectomy in a patient with primary immune thrombocytopenia and hemoperitoneum
Published 2013-08-01“…Primary immune thrombocytopenia is an acquired autoimmune disease, with a very variable clinical course, which causes an accelerated destruction by antibodies and an impaired platelet production. …”
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1055
Emerging therapeutics in idiopathic inflammatory myopathy
Published 2020-01-01“…Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of systemic autoimmune diseases characterized mainly by inflammation of muscle tissue. …”
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1056
The Microbiome in Connective Tissue Diseases and Vasculitides: An Updated Narrative Review
Published 2017-01-01“…The PubMed database was searched for articles using combinations of words or terms that included systemic lupus erythematosus, systemic sclerosis, autoimmune myositis, Sjögren’s syndrome, undifferentiated and mixed CTD, vasculitis, microbiota, microbiome, and dysbiosis. …”
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1057
Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study
Published 2019-01-01“…Psoriasis, an autoimmune disease, affects a vast number of peoples around the world. …”
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1058
Kikuchi-Fujimoto Disease: A Case Report and Literature Review
Published 2012-01-01“…No definite aetiology of KFD is known despite autoimmune and infection factors being suggested. The diagnostic hallmark is histological findings from lymph nodes. …”
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1059
A Paraneoplastic Syndrome Characterized by Extremity Swelling with Associated Inflammatory Infiltrate Heralds Aggressive Transformation of Myelodysplastic Syndromes/Myeloproliferat...
Published 2012-01-01“…There has been a long history of reports describing a variety of paraneoplastic phenomena associated with myelodysplastic syndromes, particularly those with autoimmune manifestations. We report here a series of patients with an antecedent myelodysplastic syndrome (MDS) or myeloproliferative neoplasm (MPN) that underwent aggressive transformation to acute myeloid leukemia (AML). …”
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1060
Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab
Published 2023-01-01“…An extensive laboratory workup, including uveitis workup, onconeuronal and retinal antibodies, ruled out a paraneoplastic autoimmune disorder and a granulomatous disease. Furthermore, a B-scan was performed to exclude a posterior scleritis. …”
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