-
881
Interplay of NF-κB and PPAR-γ transcription factors in patients with juvenile systemic lupus erythematosus
Published 2025-01-01“…Objective Juvenile SLE (jSLE) is an autoimmune disease characterised by the presence of high levels of autoantibodies, predominantly targeting nuclear antigens, resulting in a breakdown of self-tolerance. …”
Get full text
Article -
882
Association of PTPN22 Haplotypes (−1123G>C/+1858C>T) with Rheumatoid Arthritis in Western Mexican Population
Published 2017-01-01“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of antibodies against cyclic citrullinated peptide (anti-CCP), a consequence of the breakdown of immune tolerance. …”
Get full text
Article -
883
Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis
Published 2021-03-01“…Introduction Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease of unknown etiology which causes progressive deterioration of the joints, leading to severe pain and functional disability. …”
Get full text
Article -
884
Current Treatment Regimens and Promising Molecular Therapies for Chronic Hepatobiliary Diseases
Published 2025-01-01“…In this review, we highlight the major molecular changes occurring in patients affected by metabolic dysfunction-associated steatotic liver disease, viral hepatitis (Delta virus), and autoimmune chronic liver diseases (autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis). …”
Get full text
Article -
885
Isolated IgA Anti-β2 Glycoprotein I Antibodies in Patients with Clinical Criteria for Antiphospholipid Syndrome
Published 2014-01-01“…Seronegative antiphospholipid syndrome (SNAPS) is an autoimmune disease present in patients with clinical manifestations highly suggestive of Antiphospholipid Syndrome (APS) but with persistently negative consensus antiphospholipid antibodies (a-PL). …”
Get full text
Article -
886
Epidemiological evidence for a hereditary contribution to myasthenia gravis: a retrospective cohort study of patients from North America
Published 2020-09-01“…Furthermore, a high proportion of patients had a personal or family history of autoimmune disease. Taken together, these findings suggest a genetic contribution to the pathogenesis of myasthenia gravis.…”
Get full text
Article -
887
Cold Agglutinin Disease Unfurled in Laboratory and Blood Bank: A Little Poignant Observation Can Speak a Lot!
Published 2024-05-01“…Autoimmune hemolytic anemias (AIHAs) are hemolytic anemias characterized by the production of autoantibodies against surface antigens on red blood cells. …”
Get full text
Article -
888
Mature Ovarian Teratoma: Neurological Implications in a Young Woman
Published 2021-01-01“…Anti-NMDAR encephalitis is an autoimmune syndrome associated with antibodies against NMDA receptors. …”
Get full text
Article -
889
Second Cancers in a Patient with Gastric MALT Lymphoma
Published 2020-01-01“…Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B-cell lymphoma, which is thought to arise from a background of chronic immune stimulation, bacterial, viral, or autoimmune stimuli. Treatment advances have increased the number of MALT lymphoma survivors, but there is still debate as to whether these patients are at a higher risk of developing second cancers. …”
Get full text
Article -
890
Targeting the chemokines in acute graft-versus-host disease
Published 2025-01-01“…Chemokines exert substantial effects across various pathological conditions, including autoimmune diseases, inflammatory processes, tumorigenesis, and metastatic dissemination. …”
Get full text
Article -
891
CFAP43 variant in persistent respiratory symptoms after hematopoietic cell transplantation
Published 2024-11-01“…Abstract We describe a case of RAS-associated autoimmune leukoproliferative disease with primary ciliary dyskinesia (PCD)-like symptoms, such as recurrent pneumonia, sinusitis, and otitis media, that occurred 7 years after hematopoietic cell transplantation. …”
Get full text
Article -
892
Novel perspectives on the pharmacological treatment of thyroid-associated ophthalmopathy
Published 2025-01-01“…Thyroid-associated ophthalmopathy (TAO), an autoimmune disease closely related to thyroid dysfunction, remains a challenging ophthalmic condition among adults. …”
Get full text
Article -
893
Simultaneous treatment with benralizumab and ustekinumab in a patient with severe asthma and ulcerative colitis
Published 2025-01-01“…The burden of autoimmune diseases is rising worldwide. The expansion of the population of patients eligible for severe asthma biological therapy we are seeing in clinical practice could lead to the simultaneous use of different monoclonal antibodies. …”
Get full text
Article -
894
Role of Neutrophils in Psoriasis
Published 2020-01-01“…Emerging evidences have demonstrated that neutrophils may play a role in autoimmune diseases. The neutrophil-to-lymphocyte ratio (NLR), the activity of neutrophils, and the number of NETotic cells were significantly higher in psoriasis patients compared to healthy controls. …”
Get full text
Article -
895
Diagnostic Dilemma of Disseminated Histoplasmosis Mimicking Hemophagocytosis Lymphohistiocytosis in Patient with Rheumatoid Arthritis on Anti-TNF Therapy: Case Report and Review of...
Published 2019-01-01“…Tumor necrosis factor inhibitors (TNFi) have become the cornerstone for the treatment of rheumatoid arthritis and other systemic autoimmune conditions. However, these biologic DMARDs can lead to various opportunistic infections such as viral infection, tuberculosis, and histoplasmosis. …”
Get full text
Article -
896
Cellular Imaging at 1.5 T: Detecting Cells in Neuroinflammation using Active Labeling with Superparamagnetic Iron Oxide
Published 2004-04-01“…The ability to visualize cell infiltration in experimental autoimmune encephalomyelitis (EAE), a well-known animal model for multiple sclerosis in humans, was investigated using a clinical 1.5-T magnetic resonance imaging (MRI) scanner, a custom-built, high-strength gradient coil insert, a 3-D fast imaging employing steady-state acquisition (FIESTA) imaging sequence and a superparamagnetic iron oxide (SPIO) contrast agent. …”
Get full text
Article -
897
An Unusual Case of Systemic Lupus Erythematosus and Hemophagocytic Syndrome
Published 2016-01-01“…Hemophagocytic syndrome (HS) or hemophagocytic lymphohistiocytosis (HLH) is an immune mediated phenomenon that can occur in the setting of an autoimmune disease, chronic immunosuppression, malignancy, or infection. …”
Get full text
Article -
898
Role of Regulatory T Cells in Pathogenesis and Biological Therapy of Multiple Sclerosis
Published 2013-01-01“…It is caused by an autoimmune response to self-antigens in a genetically susceptible individual induced by unknown environmental factors. …”
Get full text
Article -
899
Cronkhite-Canada Syndrome: A Case Report and Review of Literature
Published 2009-01-01“…The disease is characterized by diffuse gastrointestinal polyposis, dystrophic changes of the fingernails, alopecia, cutaneous hyperpigmentation, diarrhea, weight loss, and abdominal pain. (2) The etiology is currently unknown, but an autoimmune process is suspected. The workup is based on history and physical followed by imaging and endoscopy with biopsy to confirm gastrointestinal polyposis. …”
Get full text
Article -
900
Oxidative stress: an overview of past research and future insights
Published 2024-12-01“…The obtained findings suggest that many diseases are linked to OS, including diabetes mellitusinflammation, cancers, autoimmune disorders and neurodegenerative diseases. …”
Get full text
Article