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Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets
Published 2025-01-01“…Abstract T cells mediate pathogenesis of several autoimmune disorders by recognizing self-epitopes presented on Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) complex. …”
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62
Safety of Cyclophosphamide Therapy in Autoimmune Rheumatic Diseases
Published 2019-01-01“…It is used as a drug of choice in many organ-threatening manifestations of systemic autoimmune rheumatic diseases (AIRDs) such as lupus nephritis, antineutrophil cytoplasmic antibody-associated vasculitis, classical polyarteritis nodosa, and myositis. …”
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63
Insulin Autoimmune Syndrome: A Systematic Review
Published 2023-01-01“…Insulin autoimmune syndrome (IAS) is a rare endocrine disorder characterized by recurrent episodes of severe hypoglycemia, markedly elevated serum insulin, and positive insulin autoantibodies. …”
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The Microbiota Determines Susceptibility to Experimental Autoimmune Uveoretinitis
Published 2016-01-01“…We found that GF mice and mice where the microbiota was reduced one week before EAU induction were protected from severe autoimmune inflammation. GF mice had lower numbers of infiltrating macrophages and significantly less T cell infiltration in the retina than CV mice with EAU. …”
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Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
Published 2015-01-01“…Therefore, the mechanism of GM-CSF-producing CD4+ T cell differentiation and the role of GM-CSF in the development of autoimmune and inflammatory diseases are gaining increasing attention. …”
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Daratumumab for autoimmune diseases: a systematic review
Published 2023-12-01“…Objective Refractory autoimmune diseases remain a significant challenge in clinical practice and new therapeutic options are needed. …”
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68
Autoimmune Polyglandular Syndrome Type 3 with Anorexia
Published 2012-01-01“…According to these findings, he was diagnosed with autoimmune polyglandular syndrome type 3 with SPIDDM, pernicious anemia, and Hashimoto's thyroiditis. …”
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Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis
Published 2015-01-01“…In both autoimmune liver disease and chronic viral hepatitis, the injury results from an immune-mediated cytotoxic T cell response to liver cells. …”
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70
An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders
Published 2019-01-01“…The induction of autoimmune responses, autoantibody production, and cytokines involved in the major autoimmune diseases will be discussed.…”
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71
The Histone Modification Code in the Pathogenesis of Autoimmune Diseases
Published 2017-01-01“…The pathogenesis of autoimmune diseases is extremely complex and remains largely unknown. …”
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72
Polycystic Ovary Syndrome May Be an Autoimmune Disorder
Published 2016-01-01“…There is an association between PCOS and autoimmune diseases such as ANA and anti-TPO that have been documented in systemic lupus erythematosus and Hashimoto thyroiditis, respectively, and it is suspected that there are autoantibodies that might affect the long term clinical management of these patients. …”
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Exploring Systemic Autoimmunity in Thyroid Disease Subjects
Published 2018-01-01“…Individuals with one autoimmune disease are at risk of developing a second autoimmune disease, but the pathogenesis or the sequential occurrence of multiple autoimmune diseases has not been established yet. …”
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Oral manifestations of autoimmune connective tissue diseases
Published 2018-01-01Subjects: “…Autoimmune…”
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Autoimmune Gastritis: Focus on Endoscopic and Morphological Characteristics
Published 2024-03-01Subjects: “…autoimmune gastritis…”
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76
The Autoimmune Profiles in the Etiopathogenesis of Granulomatous Lobular Mastitis
Published 2025-03-01Subjects: Get full text
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Notch Signaling Pathway Promotes Th17 Cell Differentiation and Participates in Thyroid Autoimmune Injury in Experimental Autoimmune Thyroiditis Mice
Published 2023-01-01“…To investigate whether the Notch signaling pathway participates in the occurrence and development of experimental autoimmune thyroiditis (EAT) by affecting the differentiation and function of Th17 cells. …”
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Peroxisome Proliferator-Activated Receptor-γ in Thyroid Autoimmunity
Published 2015-01-01“…On the contrary, pioglitazone has not shown these effects until now; this favors pioglitazone for a possible use in patients with thyroid autoimmunity. However, further studies are ongoing to explore the use of new PPAR-γ agonists in the treatment of thyroid autoimmune disorders.…”
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A Role for Folate in Microbiome-Linked Control of Autoimmunity
Published 2021-01-01“…The microbiome exerts considerable control over immune homeostasis and influences susceptibility to autoimmune and autoinflammatory disease (AD/AID) such as inflammatory bowel disease (IBD), multiple sclerosis (MS), type 1 diabetes (T1D), psoriasis, and uveitis. …”
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Osteopontin Bridging Innate and Adaptive Immunity in Autoimmune Diseases
Published 2016-01-01“…This review describes the OPN structure, isoforms, and functions and its role in regulating the crosstalk between innate and adaptive immunity in autoimmune diseases.…”
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