Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats by Awyed Batah Almutairi, Abdulaziz Arif A. Alshammari, Arshad Husain Rahmani, Ali Yousif Babiker, Long Chiau Ming, Maha A. Aldubayan, Ahmad H. Alhowail, Vasudevan Mani

“… Cyclosporine A (CYP-A), a potent immunosuppressive agent, significantly impacts organ transplantation and the treatment of autoimmune disorders, and its ability to control autoimmune reactions and prevent organ rejection has made it indispensable in contemporary medicine. …”
Get full text

pVAXhsp65 Vaccination Primes for High IL-10 Production and Decreases Experimental Encephalomyelitis Severity by Sofia Fernanda Gonçalves Zorzella-Pezavento, Fernanda Chiuso-Minicucci, Thais Graziela Donegá França, Larissa Lumi Watanabe Ishikawa, Larissa Camargo da Rosa, Priscila Maria Colavite, Bianca Balbino, Camila Marques, Maura Rosane Valerio Ikoma, Ana Paula Masson, Célio Lopes Silva, Alexandrina Sartori

“…Experimental autoimmune encephalomyelitis (EAE) is a demyelinating pathology of the central nervous system (CNS) used as a model to study multiple sclerosis immunopathology. …”
Get full text

Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D by Yang Qin, Li Liu, Yanwen Zhang, Xiaowei Chen, Jiani Zhang, Sunwang Ling, Jianguang Wang, Xinyu Yang

Get full text

Clinical Correlations of Novel Autoantibodies in Patients with Dry Eye by Sezen Karakus, Alan N. Baer, Esen K. Akpek

“…Whether these patients have an early stage of SS or a different type of autoimmune condition may be determined through longitudinal studies.…”
Get full text

Hemophagocytic lymphohistiocytosis secondary to refractory acute myeloid leukemia resolved after second line treatment with azacitidine plus venetoclax by Claudio Fozza

“…Secondary HLH typically occurs in conjunction with severe infections, malignancies or autoimmune disorders and intensive chemotherapy, potentially complicating treatment of acute myeloid leukemia (AML) in around 10% of cases. …”
Get full text

Urticarial Vasculitis-Associated Intestinal Ischemia by Uni Wong, Harris Yfantis, Guofeng Xie

“…UV is often idiopathic but can also present in the context of autoimmune disorders such as systemic lupus erythematosus, drug reactions, infections, or a paraneoplastic syndrome. …”
Get full text

Dermatomyositis Sine Myositis with Membranoproliferative Glomerulonephritis by Mohammad Bagher Owlia, Roya Hemayati, Shokouh Taghipour Zahir, Mohammad Moeini Nodeh

“…Dermatomyositis (DM) is an autoimmune disease that is characterized by involvement of proximal musculature and skin. …”
Get full text

Nonbacterial thrombotic endocarditis as a cause of systemic embolism by N.D. Oryshchyn

“…Presented case demonstrates need for awareness regarding nonbacterial thrombotic endocarditis in patients with systemic embolism and in specific groups of patients (autoimmune diseases and oncology).…”
Get full text

A Case of Acquired Hemophilia A in a Patient with Exposure to COVID-19 by Jorge D. Guerra, Jasmine Gowarty, Jordan Buess, James Mason, Kathleen Halka

“…Acquired Hemophilia A (AHA) is a very rare autoimmune condition involving immune-mediated depletion of Factor VIII, resulting in spontaneous hemorrhage. …”
Get full text

Celiac Disease Presenting as Fever of Unknown Origin by Megan J. Cooney, Wael El-Matary

“…Celiac disease (CD) is a common autoimmune enteropathy that occurs, in affected individuals, with exposure to gluten in the diet and improves with removal of dietary gluten. …”
Get full text

Acquired von Willebrand Syndrome in IgM Monoclonal Gammopathy as the Presentation of Lymphoplasmacytic Lymphoma by Zachary Wolfe, Bradley Lash

“…Most commonly implicated are lymphoproliferative, myeloproliferative, cardiovascular, and autoimmune disorders. Unlike inherited von Willebrand disease (vWD), AVWS tends to present at an older age and without a family history of vWD. …”
Get full text

Acute Respiratory Failure due to Neuromyelitis Optica Treated Successfully with Plasmapheresis by Massa Zantah, Timothy B. Coyle, Debapriya Datta

“…Neuromyelitis Optica (NMO) is a demyelinating autoimmune disease involving the central nervous system. …”
Get full text

Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms by Przemysław Borowy, Olga Wcisłek, Julia Płonczyńska, Mateusz Heba, Bogdan Batko

“…Bullous pemphigoid (BP) is a chronic autoimmune skin disease. It is characterized by the presence of well-tense blisters in the area of erythematous-oedematous eruptions, as well as in the unaffected skin that often develops lesions triggered by medications or focal points. …”
Get full text

Updates in the management of connective tissue disease-associated interstitial lung disease by Chengappa Kavadichanda, G S R S N K Naidu

“…The occurrence of interstitial lung disease (ILD) in a setting of a well-defined autoimmune disease or in the presence of autoantibodies is being increasingly recognized. …”
Get full text

Orbital Pseudotumor as an Extrahepatic Complication of Chronic HCV Infection by Owen Huang, Tina Shah, Divya Sundarapandiyan, Matthew J. Akiyama

“…He was found to have an HCV infection for unknown duration upon further investigation. All other workup (autoimmune, rheumatic, and infectious) was unrevealing. …”
Get full text

Pregnancy counseling in rheumatic diseases: Where science meets the steps by Anu Balakrishnan, Pankti Mehta, Latika Gupta

“…The knowledge, as well as practices of contraception in autoimmune diseases, are low and varied in various populations. …”
Get full text

Successful treatment of stiff-person syndrome with plasmapheresis: case report and literature review by M. Nasvytis, R. Kaladytė Lokominienė

“… Stiff-person syndrome (SPS) is a rare neurologic disease, most often caused by autoimmune process during which antibodies against glutamic acid decarboxylase (anti-GAD65) are synthesised. …”
Get full text

Hypothyroidism Complicating Nephropathy in a Diabetes Patient by Jayaprakash Sahoo, Ilangovan Veerappan, Anila Abraham, Somasundaram Hariharan

“…We describe a patient with type 2 diabetes mellitus and autoimmune hypothyroidism who presented with elevated serum creatinine possibly due to subclinical rhabdomyolysis induced by hypolipidemic drug therapy in the background of diabetic nephropathy. …”
Get full text

Behçet Disease-Like Symptoms with a Novel COPA Mutation by E. Anderson, J. Hatch, J. Cardinal, D. Langguth, D. Coman

“…These mutations lead to endoplasmic reticulum stress and autoimmune response with upregulation of Th17 cytokines. …”
Get full text

Value of EEG in the differentiation of glial tumor and encephalitis: a case report and review of literature by M. Jokubaitis, R. Mameniškienė, A. Barkauskienė, J. Valaikienė

“…The article also reviews similar cases described in the literature and EEG changes characteristic of infectious and autoimmune encephalitis. …”
Get full text