Camrelizumab-Related Lethal Arrhythmias and Myasthenic Crisis in a Patient with Metastatic Thymoma by Bo Zhang, Laxman Gyawali, Zengzhang Liu, Huaan Du, Yuehui Yin

“…However, ICI therapy has also been associated with various immune-related adverse events (irAEs), especially for patients with preexisting autoimmune status, which sometimes can be life-threatening. …”
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IPEX Syndrome with Normal FOXP3 Protein Expression in Treg Cells in an Infant Presenting with Intractable Diarrhea as a Single Symptom by Ali Al Maawali, Beata Derfalvi, Johan Van Limbergen, Andrew Issekutz, Thomas Issekutz, Hasan Ghandourah, Mohsin Rashid

“…This can lead to quantitative or functional deficiency of regulatory T cells (Treg), thereby affecting their immune-suppressive actions which can in turn cause autoimmune and inflammatory disorders. We describe an infant with IPEX syndrome with unremarkable maternal family history whose only presentations were severe diarrhea and malnutrition. …”
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siRNA therapeutics for effective management of rheumatoid arthritis by Vishakha R. Chakole, Tathagata Dutta, Priyankar Sen

“…This property makes siRNA a valuable tool for developing RNAi therapeutics, particularly for managing conditions like osteoporosis, cancer, genetic disorders, and autoimmune disorders. Rheumatoid arthritis (RA) is a significant autoimmune disorder. …”
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Clinical and Biochemical Features Used to Classify Type-1 and Type-2 Diabetes: A Scoping Review by Ulagamadesan Venkatesan, Anandakumar Amutha, Ranjit Mohan Anjana, Ranjit Unnikrishnan, Bagavandas Mappillairajan, Viswanathan Mohan

“…While age at diagnosis, autoimmune markers, and beta-cell function are among the crucial clinical parameters, biochemical indicators like C-peptide levels and antibody analyses play a pivotal role. …”
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PD-1 Blockade in Advanced Melanoma in Patients with Hepatitis C and/or HIV by Diwakar Davar, Melissa Wilson, Chelsea Pruckner, John M. Kirkwood

“…Given hypothesized risk of triggering exacerbations of autoimmune diseases and/or chronic viral infections, clinical trials (including regulatory studies) evaluating checkpoint blocking antibodies PD-1 and CTLA-4 have excluded patients with autoimmune diseases, chronic hepatitis B/C virus (HBV/HCV), and/or human immunodeficiency virus (HIV) infections. …”
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Autologous Serum Skin Test versus Autologous Plasma Skin Test in Patients with Chronic Spontaneous Urticaria by Aysegul Alpay, Nilgün Solak Tekin, Ishak Özel Tekin, H. Cevdet Altinyazar, Rafet Koca, Saniye Çınar

“…Previous studies indicate that 25–45% of chronic urticaria patients have an autoimmune etiology. Autologous serum skin test (ASST) and autologous plasma skin test (APST) are simple tests for diagnosing chronic autoimmune urticaria (CAU). …”
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IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome by Shujuan Li, Ming Yu, Haifeng Li, Hongliang Zhang, Yanfang Jiang

“…Guillain-Barré syndrome (GBS) is an acute autoimmune-mediated inflammatory demyelinating disease that causes rapidly progressing paralysis and occasionally respiratory failure. …”
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Association of Cytotoxic T Lymphocyte Antigen-4 Gene Polymorphisms with Psoriasis Vulgaris: A Case-Control Study in Turkish Population by Hatice Gül Dursun, Hüseyin Osman Yılmaz, Recep Dursun, Sevsen Kulaksızoğlu

“…Psoriasis is a common, chronic, and autoimmune skin disease in which dysregulation of immune cells, particularly T cells, is thought to play an important role in the pathogenesis. …”
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Disparate Intent-to-Treat Outcomes for Pediatric Liver Transplantation Based on Indication by Anna Lang, Cameron Goff, Ashley Montgomery, Jake Lynn, Spoorthi Kamepalli, John Goss, Abbas Rana

“…Hepatoblastoma (hazard ratio (HR): 3.73), autoimmune cirrhosis (HR: 1.86), and AHN (HR: 1.77) were associated with significantly increased intent-to-treat mortality. …”
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In silico data mining of large-scale databases for the virtual screening of human interleukin-2 inhibitors by Halim Sobia Ahsan, Zaheer-Ul-Haq, Khan Ajmal, Al-Rawahi Ahmed, Al-Harrasi Ahmed

“…Uncontrolled activated T cells play a key role in the pathophysiology by stimulating inflammation and autoimmune diseases like arthritis, psoriasis and Crohn’s disease. …”
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Variations in Rodent Models of Type 1 Diabetes: Islet Morphology by Lesya Novikova, Irina V. Smirnova, Sonia Rawal, Abby L. Dotson, Stephen H. Benedict, Lisa Stehno-Bittel

“…This study focused on 1 toxin-induced and 2 autoimmune rodent models of T1D: BioBreeding Diabetes Resistant rats, nonobese diabetic mice, and Dark Agouti rats treated with streptozotocin. …”
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Correlation between Maternal Vitamin D and Thyroid Function in Pregnancy with Maternal and Neonatal Outcomes: A Cross-Sectional Study by Salma Ahi, Mohsen Adelpour, Iman Fereydooni, Naser Hatami

“…We evaluated thyroid function tests and thyroid autoantibodies (TPOAb and TGAb), as well as the serum level of 25OHD, to determine the relationship between vitamin D level and autoimmune or non-autoimmune thyroid disease in pregnancy. …”
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Autoantibody to MDM2: A Potential Serological Marker of Systemic Lupus Erythematosus by Yuan Liu, Liping Dai, Weihong Liu, Guixiu Shi, Jianying Zhang

“…Systemic lupus erythematosus (SLE) is one of the systemic autoimmune diseases characterized by the polyclonal autoantibody production. …”
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IMPASSIVE DICTATING: A Mnemonic Acronym for Systematically Generating Differential Diagnoses by Ho M, Coloma M, Ngo R, Santhakumar J

“…IMPASSIVE DICTATING is an acronym for pathophysiologies to consider in a differential diagnosis: immune reactions and dysregulation, metabolic, psychiatric, allergic, structural, social, infectious, vascular, endocrine/exocrine, degenerative, iatrogenic, congenital, traumatic, autoimmune, toxic, idiopathic, neoplastic, and genetic. …”
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Hydroxychloroquine and Fabry Disease: Three Case Reports Examining an Unexpected Pathologic Link and a Review of the Literature by Rouhin Sen, Kathleen Borghoff, Kirk W. Foster, Stanley J. Radio, Alan Erickson, Michelene Hearth-Holmes

“…Hydroxychloroquine is an effective and widely used treatment in multiple autoimmune connective tissue diseases that gained a lot of publicity in the coronavirus disease 2019 (COVID-19) pandemic. …”
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Association of disease activity with programmed cell death 1 and its ligand programmed cell death ligand 1 expressions in lupus patients by Eman Eissa, Rania Kandil, Nehal El-Ghobashy, Walaa Abdelfattah, Zainab Hammouda, Sara Medhat Gadelsayed, Faten Bayoumi

“…Background: Programmed cell death 1(PD-1)/programmed cell death ligand 1 (PD-L1) pathway is an immune checkpoint implicated in immune tolerance and involved in the pathogenesis of several autoimmune diseases. Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple immune dysregulation. …”
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IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-γ occurs via the G-protein pathway by S. Vassiliadis, G. K. Papadopoulos

“…Major histocompatibility complex (MHC) class II antigen expression has been implicated in the pathogenesis of autoimmune type 1 diabetes. In this study we examined the role of various cytoldnes that may induce MHC class II surface antigen expression, using the rat insulinoma line RIN-5AH as a pertinent model system. …”
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Hemophagocytic Lymphohistiocytosis in a Patient with Classical Hodgkin Lymphoma by G. Hyun, K. J. Robbins, N. Wilgus, L. Grosso, S. D. Goyal

“…Extensive work-up for autoimmune and infectious etiologies was unremarkable. …”
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Selective Subnormal IgG1 in 54 Adult Index Patients with Frequent or Severe Bacterial Respiratory Tract Infections by James C. Barton, Luigi F. Bertoli, J. Clayborn Barton, Ronald T. Acton

“…Associated disorders included the following: autoimmune conditions 50.0%; hypothyroidism 24.1%; atopy 38.9%; and other allergy 31.5%. …”
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The Impact of T Cell Vaccination in Alleviating and Regulating Systemic Lupus Erythematosus Manifestation by Liuye Huang, Yuan Yang, Yu Kuang, Dapeng Wei, Wanyi Li, Qin Yin, Juan Pang, Zhongwei Zhang

“…Systemic lupus erythematosus (SLE) is an autoimmune disease identified by a plethora of production of autoantibodies. …”
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