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    A Prospective, Crossover, Randomized, Double-Blind Clinical Study Comparing the Effectiveness and Ocular Comfort of 0.1% Hyaluronic Acid and 0.3% Hyaluronic Acid in Patients With D... by Kim SJ, Yoo WS, Kwon LH, Kim RB, Yoon HJ, Yoon KC

    Published 2025-02-01
    “…Seong-Jae Kim,1,* Woong-Sun Yoo,1,* Lee-Ha Kwon,1 Rock Bum Kim,2,3 Hyeon-Jeong Yoon,4 Kyung Chul Yoon4 1Department of Ophthalmology, Institute of Medical Science, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, South Korea; 2Regional Cardiocerebrovascular Disease Center, Gyeongsang National University Hospital, Jinju, South Korea; 3Department of Preventive Medicine, Institute of Medical Science, Gyeongsang National University College of Medicine, Jinju, South Korea; 4Department of Ophthalmology, Chonnam National University Medical School, Gwangju, South Korea*These authors contributed equally to this workCorrespondence: Kyung Chul Yoon, Department of Ophthalmology, Chonnam National University Medical School, #42 Jebong-ro, Dong-gu, Gwangju, 61469, South Korea, Tel +82-62-220-6753, Fax +82-62-227-1642, Email kcyoon@jnu.ac.krPurpose: Report the clinical effects and discomfort of using 0.1% hyaluronic acid (HA [Kynex 1®, Alcon, Seoul, S. …”
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    The Comparison of Cost-Effectiveness Between Magnetic Resonance Spectroscopy and Provocative Discography in the Identification of Chronic Low Back Pain Surgery Candidates by Wilson L, Beall DP, Eastlack RK, Berven S, Lotz JC

    Published 2025-01-01
    “…A non-invasive alternative using Magnetic Resonance Spectroscopy (MRS) offers a potential solution.Context/Purpose: We assess cost-effectiveness of MRS with NOCISCAN diagnostic algorithm compared to PD for identifying lumbar discs requiring surgical intervention.Study Design/Setting: We conducted cost-effectiveness analysis using modelling.Patient Sample: We used data from a clinical study of 139 CLBP patients who met criteria for and received PD of lumbar spine and presented with an ODI score ≥ 40; comparing PD and MRS-based diagnostics.Outcome Measures: We considered diagnostic costs, adverse events, surgical costs and outcomes based on a 15-point improvement on the Oswestry Disability Index.Methods: Incremental cost-effectiveness ratios (ICERS) and probabilistic sensitivity analyses were determined. Some authors have consulted for Aclarion.Results: Mean total cost per PD patient was $59,711, and $57,998 for MRS, demonstrating $1712 cost savings per MRS diagnosed patient. …”
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