Globular-shaped Aβ oligomers have diverse mechanisms for promoting Aβ aggregations with the facilitation of fibril elongation by Hiroto Nakano, Sadao Hikishima, Makoto Mori, Jota Minamikawa, Daiki Muramatsu, Yasuhiro Sakashita, Tokuhei Ikeda, Moeko Noguchi-Shinohara, David B. Teplow, Kenjiro Ono

Get full text

Protective Effect of Rosmarinic Acid on Endotoxin-Induced Neuronal Damage Through Modulating GRP78/PERK/MANF Pathway by Li Q, Zheng JW, Wang ZY, Liao SP, Zhu L, Wang X, Wan LH

“…Qian Li,1,* Jing-Wen Zheng,1,* Zi-Yao Wang,1 Shi-Ping Liao,2 Ling Zhu,1 Xia Wang,3,* Li-Hong Wan1,4,* 1Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 2Functional Laboratory, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 3Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 4NHC Key Laboratory of Chronobiology (Sichuan University), West China School of Basic Medical Sciences & Forensic Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li-Hong Wan, Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 3-17 Renmin South Road, Sichuan, 610041, People’s Republic of China, Tel +86-28-85501278, Email wanlihong1976@sina.com Xia Wang, Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China, Email 80832491@qq.comObjective: Neuronal damage is criminal to cognitive dysfunction, closely related to endoplasmic reticulum stress (ERS). …”
Get full text

Impact of Heat on Human and Animal Health in India: A Landscape Review by Sandul Yasobant, K. Shruti Lekha, Poonam Trivedi, Shruti Krishnan, Chinmayee Kator, Harleen Kaur, Mudita Adaniya, Anish Sinha, Deepak Saxena

Get full text

Exotic Laguncularia racemosa drives rapid shifts in pond-to-mangrove restoration communities by Lin Zhang, Yamian Zhang, Yijuan Deng, Pingping Guo, Wenqing Wang, Mao Wang

Get full text

Impact of Initial Heart Rate, Diastolic Pressure, and Pulse Pressure on Prognostic Outcomes in Heart Failure Patients with Mildly Reduced Ejection Fraction by Hu H, Liu Z, Zeng J, Jiang M

“…Hailong Hu,1,* Zhican Liu,2,* Jianping Zeng,1 Mingyan Jiang2 1Department of Cardiology, Xiangtan Central Hospital, The Affiliated Hospital of Hunan University, Xiangtan, 411100, People’s Republic of China; 2Department of Pulmonary and Critical Care Medicine, Xiangtan Central Hospital, The Affiliated Hospital of Hunan University, Xiangtan, 411100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mingyan Jiang, Director of Department of Pulmonary and Critical Care Medicine, Xiangtan Central Hospital, The Affiliated Hospital of Hunan University, Xiangtan, 411100, People’s Republic of China, Email jiangmingyan1979@163.com Jianping Zeng, Director of Heart Center, Xiangtan Central Hospital, Xiangtan, 411100, People’s Republic of China, Email 571725929@qq.comBackground: Heart rate, diastolic pressure, and pulse pressure are key modifiable factors influencing heart failure prognosis. …”
Get full text

Intrahospital dissemination of multidrug-resistant Acinetobacter baumannii at a teaching hospital in Northeast of Mexico by Samantha Villarreal-Cruz, Adrián Camacho-Ortiz, Samantha Flores-Treviño, Licet Villarreal-Treviño, Paola Bocanegra-Ibarias

Get full text

Increase in disturbance-induced canopy gaps leads to reorganization of Central European bird communities by Anne Graser, Claudia Frank, Friederike Kunz, Andreas Schuldt, Cornelius Senf, Christoph Sudfeldt, Sven Trautmann, Johannes Kamp

Get full text

Development of VTOL-configured unmanned aquatic vehicle for underwater welding applications: An innovative design and multi-perspective computational investigations by Janani Priyadharshini Veeraperumal Senthil Nathan, Manikandan Arumugam, Mahendran Rajendran, Laxana Sourirajan, Gopinath Vinayagam, Akhila Ajith Pisharam, Sundhar Baskar, Beena Stanislaus Arputharaj, Subhav Singh, Khristina Maksudovna Vafaeva, Vijayanandh Raja

Get full text

Migration, race, and gender: the policing of subversive solidarity actors in Morocco by Sébastien Bachelet, Maria Hagan

“…While some interviewees demonstrated an awareness of both intersectional differences and overlapping experiences, we call for solidarity actors to mobilise these differences and experiences to strengthen their action on migration issues and their ability to withstand intimidation from state authorities.…”
Get full text

Dual inhibition of BET and EP300 has antitumor activity in undifferentiated pleomorphic sarcomas and synergizes with ferroptosis induction by Stéphanie Verbeke, Aurélien Bourdon, Mathilde Lafon, Vanessa Chaire, Bertolo Frederic, Amina Naït Eldjoudi, Marie-Alix Derieppe, Francis Giles, Antoine Italiano

Get full text

Investigating the triple-frequency ultrasound-assisted fermented rice lees: Impact on physicochemical, structural, morphological, and metabolic properties by Mian Shamas Murtaza, Sanabil Yaqoob, Bismillah Mubeen, Aysha Sameen, Mian Anjum Murtaza, Abdur Rehman, Tawfiq Alsulami, Sameh A. Korma, Ibrahim Khalifa, Yong Kun Ma

Get full text

Formation of advanced glycation end products in raw and subsequently boiled broiler muscle: biological variation and effects of postmortem ageing and storage by Suhong Huang, Xiaoli Dong, Yali Zhang, Yuru Chen, Yajie Yu, Ming Huang, Yuandong Zheng

Get full text

Decoding mutational signatures in breast cancer: Insights from a multi-cohort study by Margaux Betz, Andréa Witz, Julie Dardare, Cassandra Michel, Vincent Massard, Romain Boidot, Pauline Gilson, Jean-Louis Merlin, Alexandre Harlé

Get full text

Efficient virtual machine placement in cloud computing environment using BSO-ANN based hybrid technique by Pradeep Singh Rawat, Sachin Gaur, Varun Barthwal, Punti Gupta, Debjani Ghosh, Deepak Gupta, Joel JP C. Rodrigues

Get full text

The effect of rust layer damage on the corrosion resistance of Q420 bridge steels by Zexian Wang, Weichen Xu, Binbin Zhang, Junyi Gao, Canming Li, Guobao Li, Rongling Zhang, Baorong Hou

Get full text

Density functional theory calculation for understanding the roles of biochar in immobilizing exchangeable Al3 + and enhancing soil quality in acidic soils by Debo He, Xinyi Liu, Dongni Hu, Ping Lei, Jinbo Zhang, Zhixin Dong, Bo Zhu

Get full text

Appropriate nitrogen application under ridge-furrow plastic film mulching planting optimizes spring maize growth characteristics by improving soil quality in the Loess Plateau of C... by Fan Zhang, Mengru Chen, Yingying Xing, Xiukang Wang

Get full text

Effects of ALA-PDT on the murine footpad model of Fonsecaea monophora infection and its related mechanisms in vivo by Xuelin Wu, Wenyi Chen, Muhammad Danish Yaqoob, Kangxing Liu, Yanqing Hu, Yan Lu, Yongxuan Hu

Get full text

Exploring environmental risk in soils: Leveraging open data for non-sampling assessment? by Silvia Aparisi-Navarro, Maria Moncho-Santonja, Beatriz Defez, Carla Candeias, Fernando Rocha, Guillermo Peris-Fajarnés

Get full text

The effects of magnitude of calcium decline at the onset of lactation on serotonin dynamics and the serotonin-calcium axis by M.K. Connelly, R.M. Rodney, J. Kuehnl, J.P.N. Andrade, F. Sonnewend Andrade, S. Henschel, E. Block, I.J. Lean, L.L. Hernandez

Get full text