Clinical Outcomes of Hepatic Arterial Infusion Chemotherapy Plus Lenvatinib and Tislelizumab for Treating Hepatocellular Carcinoma and Type IV Portal Vein Tumor Thrombus by Li X, Cao K, Fu Z, Chen X, Zhong J, Liu L, Ding N, Zhang X, Qu Z, Zhu L, Zhai J

“…Xiaowei Li,* Kunkun Cao,* Zhigang Fu,* Xiaoxia Chen, Jiaming Zhong, Li Liu, Ning Ding, Xiaoli Zhang, Zengqiang Qu, Lijun Zhu, Jian Zhai Department II of Interventional Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, 200438, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian Zhai; Lijun Zhu, Department II of Interventional Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, 200438, People’s Republic of China, Email jianzhai1979@126.com; lijun_zhush@163.comPurpose: To assess the activity and toxicity of hepatic arterial infusion chemotherapy (HAIC)+tislelizumab+lenvatinib (HAIC+tisle+len) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) type IV (Vp4 hCC) in a real-world context.Methods: Fifty-five patients, with Vp4 hCC receiving HAIC+tisle+len therapy from April 2021 to December 2022, were analyzed retrospectively. …”
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Improvement of the management system of the pharmaceutical service of the health care institution by Ye.V. Zalyhina

“…A statistically significant negative rank correlation of average strength was observed between the amount of expenses for medical care of one patient and the level of errors in prescribing medicines for the considered period (r= -0.49; 95% CI (-0.67)–(-0.26); p<0.001), which contradicts the generally accepted notion and, according to the authors, is related to the uniqueness of the situation during the considered period (first the pandemic, then the war). …”
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Comparative Efficacy of Esketamine vs Sufentanil with Propofol for Sedation in EUS: A Randomized, Controlled Study by Liu C, Wang Y, Yin Y, Wang P, Ji X, Sun J, Zhao S, Jia Y, Liu S, Zhou Z

“…Cuicui Liu,1,&ast; Yanting Wang,1,&ast; Yanwei Yin,2 Pei Wang,1 Xiangyu Ji,1 Jian Sun,1 Shuo Zhao,1 Yanfang Jia,1 Shanling Liu,1 Zangong Zhou1 1Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China; 2Pain Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zangong Zhou, Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Shinan District, Qingdao, Shandong Province, 266000, People’s Republic of China, Tel +86 532-82912511, Email zhouzangong@qdu.edu.cnPurpose: This randomized, controlled trial aimed to assess the sedative effects of esketamine and sufentanil combined with propofol during EUS.Patients and Methods: Three hundred and forty patients undergone EUS were randomly divided into two groups to receive esketamine 0.25 mg/kg combined with propofol (esketamine group) or sufentanil 0.1 μg/kg combined with propofol (sufentanil group). …”
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Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis by Lin W, Wang Q, Liu J, Tan Q

“…Weiyi Lin,1,2,&ast; Qiuzhou Wang,2,&ast; Jia Liu,1,2 Qiuwen Tan1,2 1Division of Breast Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, People’s Republic of China; 2Breast Center, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Qiuwen Tan, Division of Breast Surgery, Department of General Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Alley, Chengdu City, Sichuan Province, 610041, People’s Republic of China, Email hxtanqiuwen@163.comPurpose: Corticosteroids are recommended as a first-line treatment for idiopathic granulomatous mastitis (IGM), a disease that usually occurs in young women. …”
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Single-Cell RNA-Seq Uncovers Cellular Heterogeneity from Deep Fascia in Necrotizing Fasciitis Patients by Wang T, Zhang L, Chen W, Long Y, Zhang Y, Wang L, Hou Z

“…Tao Wang,1,&ast; Liping Zhang,2,&ast; Wei Chen,3 Yubin Long,3 Yingze Zhang,3– 6 Ling Wang,3 Zhiyong Hou3– 6 1Department of Lower Limb Trauma, Beijing Jishuitan Hospital, Guizhou Hospital, Guiyang, Guizhou, People’s Republic of China; 2Department of Physiology, Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 3Department of Orthopaedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 4Engineering Research Center of Orthopedic Minimally Invasive Intelligent Equipment, Ministry of Education, Shanghai, People’s Republic of China; 5Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, People’s Republic of China; 6NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zhiyong Hou, Department of Orthopaedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. …”
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Global Trends in the Incidence and Primary Causes of Femoral Fractures, Excluding Femoral Neck Fractures: A Global Epidemiological Study by Fu F, Liu B, Pu H, Wang Y, Zhang P, Wei S, Gu H, Zhang Q, Ye H

“…Fanyu Fu,1,&ast; Bo Liu,2,&ast; Haifang Pu,3 Yuebin Wang,3 Pengfei Zhang,1 Song Wei,1 Hao Gu,1 Qian Zhang,4 Hengli Ye5 1College of Physical Education and Health Science, Yibin University, Yibin, 644000, People’s Republic of China; 2Department of Orthopedics and Traumatology, Yibin Hospital of Traditional Chinese Medicine, Yibin, 644600, People’s Republic of China; 3Department of Pain, the Second People’s Hospital of Yibin, Yibin, 644000, People’s Republic of China; 4Department of Rheumatology and Immunology, Taizhou First People’s Hospital, Taizhou, 318020, People’s Republic of China; 5Department of Orthopaedics and Joints, Huangyan Hospital of Traditional Chinese Medicine, Taizhou, 318020, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Hengli Ye, Huangyan Hospital of Traditional Chinese Medicine, 83 Century Avenue, Xinqian Street, Huangyan District, Taizhou, 318020, China, Email dryehengli@126.comPurpose: Fractures pose a significant global health challenge, with varying incidence trends and causes across demographics and regions. …”
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Clinical Activity of Behcet&rsquo;s Disease Associated with SARS-CoV-2 and Herpes Simplex Virus: Insights from Three Case Reports by Bakti FU, Sufiawati I

“…Fitrah Utari Bakti,1,&ast; Irna Sufiawati2,&ast; 1Oral Medicine Residency, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia; 2Department of Oral Medicine, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia&ast;These authors contributed equally to this workCorrespondence: Irna Sufiawati, Department of Oral Medicine, Faculty of Dentistry, Universitas Padjadjaran, Jl. …”
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Association Between Dietary Inflammatory Index and Triglyceride Glucose-Body Mass Index with Iron Deficiency in Reproductive Age Women: Evidence from NHANES 2005-2018 by Ding J, Xu Z, Liang R, Xie S

“…Jia Ding,1,&ast; Zhehao Xu,2,&ast; Ruiyun Liang,3 Shuangfeng Xie1 1Department of Hematopathology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Department of General Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 3Department of Respiratory Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Shuangfeng Xie, Email xiesf@163.comBackground & Aims: There is a growing focus on the role of dietary factors and metabolic conditions in the evolution and progression of iron deficiency (ID), yet few studies have examined the underlying mechanisms. …”
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A simple model of the rheological curve of HPAM solutions at different temperatures by Eduar Pérez, Dario Alviso, Mauricio Carmona, Eduardo Manrique, Guillermo Artana

“…The regression model developed was fitted with a training dataset and has exhibited satisfactory results, as tested with additional experimental datasets from different authors. The metrics used to quantify the agreement of viscosities between the model and experiments demonstrate satisfactory behavior in the shear thinning range of shear rates and the shear range lower than 7.3 s−1.…”
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O debate entre cosmopolitismo, patriotismo e nacionalismo: uma introdução geral ao tema by Mariane Gehlen Perin

“…In regards to nationalism and patriotism, I present Hobsbawm’s analysis. The author, through a critical historical reconstruction of the use of the terms “nation” and “fatherland”, shows that nationalism and patriotism are phenomena originated after the 19th century. …”
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Outcomes of Worsened Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Replacement by Hu Z, Wang C, Luo S, Yang B, Zheng S, Hu X, Sun Y, Chen J, Fu M, Fan R, Luo J, Li J

“…Ziyang Hu,1,&ast; Changjin Wang,2,&ast; Songyuan Luo,2,&ast; Bangyuan Yang,2 Shengneng Zheng,3 Xiaolu Hu,2,4 Yinghao Sun,2 Jiaohua Chen,2 Ming Fu,2 Ruixin Fan,5 Jianfang Luo,2,4 Jie Li2 1Department of Cardiology, Zhongshan Hospital of Traditional Chinese Medicine, Zhongshan, People’s Republic of China; 2Department of Cardiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 3Department of Radiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 4School of Medicine South China University of Technology, Guangzhou, People’s Republic of China; 5Department of Cardiac Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jie Li; Jianfang Luo, Guangdong Provincial People’s Hospital, &num;96 Dongchuan Road, Yuexiu District, Guangzhou, Guangdong, 510080, People’s Republic of China, Tel +86 020 83827812, Email leomoku1981@163.com; jianfangluo@sina.comBackground: Left ventricular ejection fraction (LVEF) worsening after transcatheter aortic valve replacement (TAVR) was common in clinical practice. …”
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Shared Genes and Pathways in Ulcerative Colitis and Ankylosing Spondylitis: Functional Validation and Implications for Diagnosis by Li L, An G, Li F, Zhang D, Zhu X, Liang C, Zhao Y, Xie K, Zhou P, Zhu H, Jin X, Du L

“…Lin Li,&ast; Guangqi An,&ast; Fuzhen Li,&ast; Donghui Zhang, Xinyue Zhu, Chunyu Liang, Yu Zhao, Kunpeng Xie, Pengyi Zhou, Haiyan Zhu, Xuemin Jin,&ast; Liping Du&ast; Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Henan Province Eye Hospital, Henan International Joint Research Laboratory for Ocular Immunology and Retinal Injury Repair, Zhengzhou, Henan, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xuemin Jin; Liping Du, Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450000, People’s Republic of China, Tel +8613603983193 ; +8613838191481, Email jinxuemin@zzu.edu.cn; dulplab@live.cnBackground: Associations between ulcerative colitis (UC) and ankylosing spondylitis (AS) have been reported in multiple studies, but the common etiologies of UC and AS remain unknown. …”
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The Contemporary Critical Reception of Walter Pater: Retrospective and Proleptical Views by Geoffrey Sadock

“…Leading scholars have devoted the better part of their professional lives to him and have become far more reliable and candid authorities than any who wrote between the 1860s and the 1970s.It is high time for scholars concerned about his literary reputation to assess 20th and 21st century perceptions of Pater, to elucidate his continuing hold on the modern literary imagination, and to review the critical tradition of the last 35 years. …”
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Apoptotic Vesicles Attenuate Acute Lung Injury via CD73-Mediated Inhibition of Platelet Activation and NETosis by Tan L, Zhang C, Kou X, Zhao L, Wu D, Li J, Yu C, Xu T, Gao L, Mao X, Zhao C

“…Lingping Tan,1,2,&ast; Chi Zhang,1,2,&ast; Xiaoxing Kou,1– 3 Lu Zhao,4 Di Wu,1– 3 Jinyu Li,1,2 Chuanying Yu,1,2 Tansi Xu,1,2 Li Gao,1,2 Xueli Mao,1– 3 Chuanjiang Zhao1,2 1Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, People’s Republic of China; 3South China Center of Craniofacial Stem Cell Research, Guangzhou, People’s Republic of China; 4Department of Orthodontics, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou, Guangdong, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Chuanjiang Zhao, Department of Periodontology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, 510055, People’s Republic of China, Email zhaochj@mail.sysu.edu.cn Xueli Mao, South China Center of Craniofacial Stem Cell Research, Guanghua School and Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, 510080, People’s Republic of China, Email maoxuel@mail.sysu.edu.cnIntroduction: Acute respiratory distress syndrome (ARDS) is a life-threatening type of acute lung injury (ALI) characterized by elevated mortality rates and long-term effects. …”
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Micro-Electro Nanofibrous Dressings Based on PVDF-AgNPs as Wound Healing Materials to Promote Healing in Active Areas by Liu T, Xie F, Geng L, He R, Sun M, Ni T, Xu P, Xing C, Peng Y, Chen K, Fang Y

“…Tiantian Liu,1,2,&ast; Feifei Xie,3,4,&ast; Lele Geng,1,2 Ruizhe He,1,2 Mengzhe Sun,1,2 Tao Ni,1,2 Peng Xu,1,2 Chao Xing,1,2 Yinbo Peng,1,2 Ke Chen,3,4 Yong Fang1,2 1Department of Burns and Plastic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Institute of Traumatic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 4Shanghai Key Laboratory of Materials Laser Processing and Modification, Shanghai Jiao Tong University, Shanghai, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yong Fang, Department of Burns and Plastic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China, Email fangyong1020@hotmail.com Ke Chen, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, People’s Republic of China, Email chenke83@sjtu.edu.cnPurpose: The purpose of this study is to develop an innovative solution for chronic wounds in high-mobility areas, such as joints, where conventional treatments are hindered by passive healing mechanisms and the need for immobilization. …”
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The Application of Machine Learning Algorithms to Predict HIV Testing in Repeated Adult Population–Based Surveys in South Africa: Protocol for a Multiwave Cross-Sectional Analysis... by Musa Jaiteh, Edith Phalane, Yegnanew A Shiferaw, Refilwe Nancy Phaswana-Mafuya

“…Ethics approval for this study was obtained from the University of Johannesburg Research and Ethics Committee on April 23, 2024 (REC-2725-2024). The authors were given access to all five SABSSM datasets by the HSRC on August 20, 2024. …”
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Efficacy, safety and cost-effectiveness of obinutuzumab in patients with follicular lymphoma: a rapid review by Chao Wang, Yunzhuo Dong, Peng Men, Ruixia Zhang, Ying Xiao, Yishan Bu, Yinpeng Qin, Xinran Zhang, Qianqian Dou, Yiheng Yang, Huier Gao, Yi Zhang

“…The literature was screened based on predefined inclusion and exclusion criteria, and data were meticulously extracted and synthesized by two authors. Simultaneously, the quality of the literature was thoroughly assessed.ResultsObinutuzumab based chemotherapy (the chemotherapy regimen-cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP); cyclophosphamide, vincristine, and prednisone (CVP); or bendamustine) significantly prolonged progression free survival (PFS) compared to other chemotherapy regimen at primary and updated analyses. …”
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Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products by Maihöfner C, Mallick-Searle T, Vollert J, Kalita P, Sood Sethi V

“…Ltd, SingaporeCorrespondence: Vidhu Sood Sethi, GSK Consumer Healthcare Singapore Pte Ltd (Co Regn No. 201309040M), 23 Rochester Park &num;03-02, 139234, Singapore, Tel +6596447203, Email vidhu.x.sethi@haleon.comAbstract: In recent years, regulatory authorities have signaled a willingness to consider real-world evidence (RWE) data to support applications for new claims and indications for pharmaceuticals. …”
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&beta;-Caryophyllene and Statins in Bone Fracture Healing &ndash; A Narrative Review by Marom H, Khan MA, Darvish N, Tornetta III P, Khoury A, Weil YA, Skelley NW, Allison DC, Meiron S, Ehrmann Barr T

“…Hilik Marom,1,&ast; Mansoor A Khan,1,&ast; Nissim Darvish,2,&ast; Paul Tornetta III,3,&ast; Amal Khoury,4,&ast; Yoram A Weil,5,&ast; Nathan WM Skelley,6,&ast; Daniel C Allison,7,&ast; Sahar Meiron,2,&ast; Tami Ehrmann Barr1,&ast; 1R&D, OrthoTreat Ltd, Tel Aviv-Jaffa, Israel; 2Corporate Office, OrthoTreat Ltd, Tel Aviv-Jaffa, Israel; 3Department of Orthopaedic Surgery and Orthopaedic Trauma, Chobanian and Avedisian School of Medicine, Boston Medical Center, Boston, MA, USA; 4Division of Orthopaedic Surgery, Orthopaedic, and Reconstructive Trauma Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; 5Department of Orthopaedics, Hadassah Hebrew University Hospital, Jerusalem, Israel; 6Department of Orthopaedics, Sanford Health, Sioux Falls, SD, USA; 7Department of Orthopaedic Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA&ast;These authors contributed equally to this workCorrespondence: Tami Ehrmann Barr, Email drbarr@orthotreat.ioAbstract: Bone fractures are a leading cause of morbidity and healthcare expenditure globally. …”
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Molecular Characterization and Risk Factors of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolated from Chinese Tertiary Hospital by Zhu R, Li J, Lian S, Li Y, Cai M, Cao Y, Xu X

“…Rongping Zhu,1,&ast; Ju Li,2,&ast; Siyan Lian,2,&ast; Yishan Li,3 Meili Cai,2 Yingping Cao,2 Xiaohong Xu2,4 1Department of Blood Transfusion, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, Fujian, 350001, People’s Republic of China; 2Department of Laboratory Medicine, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, People’s Republic of China; 3Anxi County Traditional Chinese Medicine Hospital, Quanzhou, Fujian, 362000, People’s Republic of China; 4Fujian Medical University Union Clinical College, Fuzhou, Fujian, 350001, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xiaohong Xu; Yingping Cao, Department of Clinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, People’s Republic of China, Tel +86 13959192290 ; +86 13365910806, Email vancy1988@163.com; caoyingping@aliyun.comBackground: Therefore, the objectives of this study were to investigate the prevalence of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) in Fujian Medical University Union Hospital, identify their genetic characters, characterize their resistance profiles, and identify risk factors for their infection to improve prevention and treatment strategies for CR-hvKp in the area.Methods: Between January 2021 and January 2022, clinically identified carbapenem-resistant Klebsiella pneumoniae (CRKp) isolates were collected. …”
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