The responses of vegetation water use efficiency to biomass density and CO2 balance in dryland of Central Asia during 21st century by Alphonse Kayiranga, Xi Chen, Xuexi Ma, Dative Ingabire, Tie Liu, Yaoming Li, Emeka Edwin Igboeli, Eldiiar Duulatov, Hubert Hirwa, Clement Nzabanita, Ping Hu

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SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer by Xudong Li, Jingjing Ge, Mengdi Wan, Tongtong Feng, Xiaoqian Li, Haibo Zhang, Zhangyan Wang, Yongsheng Gao, Meiting Chen, Fei Pan

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Aberrant functional connectome gradient and its neurotransmitter basis in Parkinson's disease by Tao Guo, Cheng Zhou, Jiaqi Wen, Jingjing Wu, Yaping Yan, Jianmei Qin, Min Xuan, Haoting Wu, Chenqing Wu, Jingwen Chen, Sijia Tan, Xiaojie Duanmu, Baorong Zhang, Xiaojun Xu, Minming Zhang, Xiaojun Guan

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NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression by Wenchao Xu, Jianzhou Liu, Qiaofei Liu, Jia Xu, Li Zhou, Zhiyong Liang, Haoran Huang, Bowen Huang, Gary Guishan Xiao, Junchao Guo

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Effects of water flow treatment on muscle quality, nutrient composition and volatile compounds in common carp (Cyprinus carpio) by Lei Wang, Lingran Wang, Chang Liu, Di Feng, Jintai Huang, Zhan Jin, Fangran Ma, Jiaxin Xu, Yuyue Xu, Meng Zhang, Miao Yu, Hongxia Jiang, Zhigang Qiao

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Psychological discomfort in carriers and non-carriers of the Huntington disease mutation and its relationship with disease burden by Y. Rodríguez-Agudelo, M. Chávez-Oliveros, A. Ochoa-Morales, L. Martínez-Ruano, A. Camacho-Molina, F. Paz-Rodríguez

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Geography and age drive racial and ethnic disparities in hospital mortality for paediatric community-acquired pneumonia in the United States: a retrospective population based cohor... by Cody-Aaron L. Gathers, Nadir Yehya, Anireddy Reddy, Paula M. Magee, Vanessa C. Denny, Michelle R. Mayeda, Amanda O’Halloran, Sanjiv D. Mehta, Stephanie Wanamaker, Jessica C. Fowler, Garrett Keim

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Earth–lunar thermal effect on the temperature stability of TianQin telescope and the suppression methods by Wenbo Chang, Yuxiang Wang, Wenhai Tan, Guanhua Wu, Houyuan Chen, Wei Li, Zizheng Li, Fan Zhu, Zhu Li, Xuefeng Zhang, Shanqing Yang

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Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context by Hui Ying, Xueyan Wu, Xiaojing Jia, Qianqian Yang, Haoyu Liu, Huiling Zhao, Zhihe Chen, Min Xu, Tiange Wang, Mian Li, Zhiyun Zhao, Ruizhi Zheng, Shuangyuan Wang, Hong Lin, Yu Xu, Jieli Lu, Weiqing Wang, Guang Ning, Jie Zheng, Yufang Bi

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Révision de l’espèce Homo erectus (Dubois, 1893) by Valéry Zeitoun

“…The reconstruction of this evolutionary pattern should be matched with other data (dating, biogeography) to allow to reconstruct a real evolutionary synopsis.According to several authors (Stringer, 1984; Hublin, 1986; Kennedy, 1991; Brauer and Mbua, 1992) the existence of autapomorphic features for Homo erectus is not proved. …”
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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…It is worth noting that people with COVID-19 like symptoms are instead advised by the competent authorities not to go to hospitals and remain at home and although there is a high chance they are infected are not counted as such. …”

Trifluridine-tipiracil in previously treated patients with oestrogen receptor-positive, HER2-negative metastatic breast cancer (BOOG 2019-01 TIBET trial): a single-arm, multicentre... by Niels A.D. Guchelaar, Ron H.J. Mathijssen, Maaike de Boer, Marlies L. van Bekkum, Joan B. Heijns, Birgit E.P.J. Vriens, Mandy M. van Rosmalen, Lonneke W. Kessels, Lisanne Hamming, Karin J. Beelen, Peter Nieboer, Susan M. van den Berg, Esther Oomen-de Hoop, Rhodé M. Bijlsma, Monique E.M.M. Bos

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Barcelona scale for buccophonatory apraxia: Quantitative assessment tool by N. Montagut, S. Borrego-Écija, J. Herrero, A. Lladó, M. Balasa, E. Muñoz, F. Valldeoriola, R. Sánchez-Valle

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Urethra-sparing prostate cancer radiotherapy: Current practices and future insights from an international survey by Jennifer Le Guévelou, Paul Sargos, Piet Ost, Filippo Alongi, Stefano Arcangeli, Alejandro Berlin, Pierre Blanchard, Anna Bruynzeel, Olivier Chapet, Alan Dal Pra, Robert T. Dess, Matthias Guckenberger, Andrew Loblaw, Amar U. Kishan, Barbara Alicja Jereczek-Fossa, David Pasquier, Mohamed Shelan, Shankar Siva, Alison C. Tree, Costantinos Zamboglou, Stephane Supiot, Vedang Murthy, Thomas Zilli

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Comparison of clinical metagenomics with 16S rDNA Sanger sequencing for the bacteriological diagnosis of culture-negative samples by Camille d’Humières, Skerdi Haviari, Marie Petitjean, Laurène Deconinck, Signara Gueye, Nathan Peiffer-Smadja, Lynda Chalal, Naima Beldjoudi, Geoffrey Rossi, Yann Nguyen, Charles Burdet, Ségolène Perrineau, Diane Le Pluart, Roza Rahli, Michael Thy, Piotr Szychowiak, Xavier Lescure, Véronique Leflon-Guibout, Victoire de Lastours, Etienne Ruppé

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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma by Seema Chugh, Jean C. Tien, Jennifer Hon, Carson Kenum, Rahul Mannan, Yunhui Cheng, Chi Chiang Li, Zainab I. Taher, Andrew D. Delekta, Pushpinder Singh Bawa, Ingrid J. Apel, Stephanie J. Miner, Xuhong Cao, Rohit Mehra, Saravana M. Dhanasekaran, Yuanyuan Qiao, Rajen Mody, Arul M. Chinnaiyan

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Association of clinical signs of possible serious bacterial infections identified by community health workers with mortality of young infants in South Asia: a prospective, observat... by Gary L. Darmstadt, Saifuddin Ahmed, Mohammad Shahidul Islam, Safa Abdalla, Shams El Arifeen, Melissa L. Arvay, Abdullah H. Baqui, Zulfiqar A. Bhutta, Anuradha Bose, Nicholas E. Connor, Belal Hossain, Rita Isaac, Arif Mahmud, Dipak K. Mitra, Luke C. Mullany, Imran Nisar, Kalpana Panigrahi, Pinaki Panigrahi, Qazi Sadeq-ur Rahman, Senjuti Saha, Sajid B. Soofi, Nardos Solomon, Mathuram Santosham, Stephanie J. Schrag, Shamim A. Qazi, Samir K. Saha

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Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212... by Arndt Stahler, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Lothar Müller, Ludwig Fischer von Weikersthal, Karel Caca, Eray Goekkurt, Alexej Ballhausen, Greta Sommerhäuser, Annabel H.S. Alig, Swantje Held, Armin Jarosch, David Horst, Anke Reinacher-Schick, Stefan Kasper, Volker Heinemann, Sebastian Stintzing, Tanja Trarbach, Dominik P. Modest

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Risk of aortic aneurysm or dissection following use of fluoroquinolones: a retrospective multinational network cohort studyResearch in context by Jack L. Janetzki, Jung Ho Kim, Evan Minty, Jung Ah Lee, Daniel R. Morales, Rohan Khera, Chungsoo Kim, Thamir M. Alshammari, Scott L. DuVall, Michael E. Matheny, Thomas Falconer, Seonji Kim, Thanh-Phuc Phan, Phung-Anh Nguyen, Min-Huei Hsu, Jason C. Hsu, Rae Woong Park, Kenneth K.C. Man, Sarah Seager, Mui Van Zandt, James P. Gilbert, Patrick B. Ryan, Martijn J. Schuemie, Marc A. Suchard, George Hripcsak, Nicole Pratt, Seng Chan You

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Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Bet... by Andersson A, Bergqvist J, Schiöler L, Bossios A, Farnebo L, Holmlund T, Janson C, Keceli S, Ljunggren M, Malinovschi A, Memarian E, Nihlén U, Nilsson PM, Pesonen I, Sjöström M, Stenfors N, Sundbom F, Werner M, Torén K, Sköld M, Hellgren J

“…Anders Andersson,1,2,* Joel Bergqvist,3,4,* Linus Schiöler,5 Apostolos Bossios,6,7 Lovisa Farnebo,8,9 Thorbjörn Holmlund,10 Christer Janson,11 Sumru Keceli,12 Mirjam Ljunggren,11 Andrei Malinovschi,13 Ensieh Memarian,14 Ulf Nihlén,15 Peter M Nilsson,16,17 Ida Pesonen,18,19 Marcus Sjöström,10 Nikolai Stenfors,20 Fredrik Sundbom,11 Mimmi Werner,10 Kjell Torén,5,21 Magnus Sköld,22,23 Johan Hellgren24,25 1COPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden; 2COPD Center, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 3Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden; 4Centre for Sleep and Wake Disorders, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 5Occupational and Environmental Medicine, School of Public Health and Community Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 6Karolinska Severe Asthma Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden; 7Division of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; 8Linköping University Faculty of Medicine and Health Sciences, Department of Biomedical and Clinical Sciences, Division of Sensory Organs and Communication, Linköping, Sweden; 9Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Otorhinolaryngology, Linköping, Sweden; 10Department of Clinical Sciences, Otorhinolaryngology, Umeå University, Umeå, Sweden; 11Department of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden; 12Department of Otorhinolaryngology in Linköping, Region Östergötland, Linköping, Sweden; 13Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden; 14Department of Clinical Sciences, IKVM, Internal Medicine, Lund University, Malmö, Sweden; 15Department of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden; 16Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden; 17Clinical Research Unit, Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden; 18Respiratory Medicine Unit, Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden; 19Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden; 20Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden; 21Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden; 22Department of Respiratory Medicine and Allergy, Karolinska University Hospital Solna, Stockholm, Sweden; 23Respiratory Medicine Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; 24Department of Otorhinolaryngology, Head & Neck Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden; 25Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden*These authors contributed equally to this workCorrespondence: Anders Andersson, COPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Bruna Stråket 11B, Göteborg, 413 46, Sweden, Email Anders.Andersson@lungall.gu.sePurpose: Chronic rhinosinusitis (CRS) is related to asthma and chronic obstructive pulmonary disease (COPD). …”
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