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    Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

    Published 2025-01-01
    “…Hui Liu,1,* Siyun Liu,1,* Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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    Family Function and Self-Management of Patients With Early Chronic Kidney Disease: The Mediating Roles of Self-Perceived Burden and Ego Depletion by Cui Y, Liu N, Guo Z, Liu Q, Zhang M, Li J, Mu H, Zhang Y, Chen X

    Published 2025-01-01
    “…Yi Cui,1 Na Liu,1 Zhihua Guo,2 Qin Liu,1 Man Zhang,3 Jiayao Li,1 Hezi Mu,4 Yinling Zhang,1,* Xia Chen5,* 1Department of Nursing, Air Force Medical University, Xi’an, People’s Republic of China; 2Department of Military Medical Psychology, Air Force Medical University, Xi’an, People’s Republic of China; 3Department of Nursing, Shaanxi Provincial People’s Hospital, Xi’an, People’s Republic of China; 4Department of Orthopedics, The Second Affiliated Hospital of Air Force Medical University, Xi’an, People’s Republic of China; 5Department of Nursing, Peking University Shenzhen Hospital, Shenzhen, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yinling Zhang, Department of Nursing, Air Force Medical University, Xi’an, 710000, People’s Republic of China, Email zyl-ylz@163.com Xia Chen, Department of Nursing, Peking University Shenzhen Hospital, Shenzhen, 518036, People’s Republic of China, Email 1328219974@qq.comBackground: Effective self-management in the early stage of chronic kidney disease (CKD) is key to delaying disease progression. …”
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