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21341
Examining the Prevalence and Associated Factors of Sexually Transmitted Infections in People Living With HIV/AIDS at a Community Health Center in Bandung City, Indonesia
Published 2025-02-01“…Sani Nuraeni,1,* Sofa Dewi Alfian,2,3 Irma Melyani Puspitasari2,3,* 1Master of Pharmacy Program, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 3Center of Excellence for Pharmaceutical Care Innovation (PHARCI), Universitas Padjajdjaran, Sumedang, Indonesia*These authors contributed equally to this workCorrespondence: Irma Melyani Puspitasari, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia, Tel +62 22 84288888 Ext 3510, Email irma.melyani@unpad.ac.idPurpose: This study aims to investigate the prevalence of sexually transmitted infections (STIs) and associated factors among people living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) (PLWHA) registered in a community health center (CHC) with HIV/AIDS support and treatment services in Indonesia.Methods: A cross-sectional study that included all PLWHA data from medical records registered in a CHC with HIV/AIDS support and treatment services was conducted in Bandung City, Indonesia, between March 2019 and March 2024. …”
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21342
FEAR OF SOCIAL ALIENATION OF LOVE AS GENDER CHARACTERISTICS
Published 2019-06-01“…Theoretical basis. The authors determine that in the gender approach the subject, who is cognized, has specific desires and interests. …”
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21343
Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease
Published 2025-02-01“…Haichen Wang,1,* Feifei Zhou,2,* Mengdan Shen,1 Ronglin Ma,1 Qiang Yu1 1Department of Gastroenterology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, 215002, People’s Republic of China; 2Department of Gastroenterology, Suzhou City Wuzhong District Chengnan Street Community Health Service Center, Suzhou, Jiangsu, 215002, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qiang Yu; Ronglin Ma, Email yuqiang0102sz@163.com; maronglin573@163.comAbstract: Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, primarily arises from defects in the colonic barrier, imbalances of the gut microbiota, and immune response issues. …”
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21344
DIGITISATION OF LEGAL ALGORITHMS TO PREVENT PUBLIC PROCUREMENT CORRUPTION
Published 2024-12-01“…The absence of confidence in public authorities' effective utilisation of budgetary funds engenders inherent justifications for entrepreneurs, their employees, and other members of the public to conceal resources from irresponsible or negligent public officials, particularly in the context of cryptocurrency assets. …”
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21345
Increased Co-Expression of PD-L1 and CTLA-4 Predicts Poor Overall Survival in Patients with Acute Myeloid Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation
Published 2025-01-01“…Cunte Chen,1,2,* Kangjie Qiu,2,* Jie Chen,3,* Shunqing Wang,1 Yuping Zhang,1 Caixia Wang,1 Yangqiu Li2 1Department of Hematology, Guangzhou First People’s Hospital, Institute of Blood Transfusion and Hematology, Guangzhou Medical University, Guangzhou, 510180, People’s Republic of China; 2Institute of Hematology, School of Medicine, Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, People’s Republic of China; 3Department of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yangqiu Li, Institute of Hematology, School of Medicine, Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, 510632, People’s Republic of China, Email yangqiuli@hotmail.com Caixia Wang, Department of Hematology, Guangzhou First People’s Hospital, Institute of Blood Transfusion and Hematology, Guangzhou Medical University, Guangzhou, 510180, People’s Republic of China, Email wangcx225@163.comPurpose: Our previous study has demonstrated that high expression of immune checkpoints (ICs) was significantly associated with adverse clinical outcomes in patients with acute myeloid leukemia (AML). …”
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21346
Measuring. Monitoring. Management. Control
Published 2024-12-01“…To solve this problem, the authors propose the combination and integration of non-precision measurements, which, in turn, requires determining the threshold values of measurement errors. …”
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21347
Impact of Herpesvirus Detection via Metagenomic Next-Generation Sequencing in Patients with Lower Respiratory Tract Infections
Published 2025-01-01“…., Ltd, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Gai, WillingMed Technology (Beijing) Co., Ltd, No. 156 Jinghai 4th Road, Beijing Economic and Technological Development Zone, Beijing, 101103, People’s Republic of China, Email weigai@willingmed.com Huaying Wang, The Affiliated People’s Hospital of Ningbo University, Yinzhou People’s Hospital, No. 251, Baizhang East Road, Ningbo, 315040, People’s Republic of China, Email yingmeire@163.comPurpose: This study aimed to investigate the impact of herpesvirus detection by metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) on lower respiratory tract infections (LRTIs) patients’ lung microbiome composition and prognosis.Patients and methods: We initially enrolled 234 hospitalized patients with LRTIs who underwent BALF mNGS between February 2022 and May 2023. …”
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21348
How Does Indonesian Chronic Disease Patient Adhere to Their Treatment? A Cross-Sectional Analysis of 11,408 Subjects
Published 2025-01-01“…Ivan Surya Pradipta,1,2,* Kevin Aprilio,1,2,* Yozi Fiedya Ningsih,1,2 Mochammad Andhika Aji Pratama,2 Vesara Ardhe Gatera,3 Sofa Dewi Alfian,1,2 Aulia Iskandarsyah,4 Rizky Abdulah1,2 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 2Drug Utilization and Pharmacoepidemiology Research Group, Center of Excellence in Higher Education for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 3Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 4Department of Clinical Psychology, Faculty of Psychology, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia*These authors contributed equally to this workCorrespondence: Ivan Surya Pradipta, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jalan Ir. …”
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21349
LBP-CD155 Liposome Nanovaccine Efficiently Resist Colorectal Cancer and Enhance ICB Therapy
Published 2025-01-01“…Yajuan Yan,1,* Ting Duan,1,* Xiaonan Xue,1,* Xiaojuan Yang,2 Miao Liu,2 Bin Ma,3,4 Xiangguo Duan,2 Chunxia Su1 1Department of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2Department of Inspection, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 3Department of Surgery, The First People’s Hospital of Yinchuan, Yinchuan, Ningxia, People’s Republic of China; 4The Second School of Clinical Medicine, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chunxia Su; Xiangguo Duan, Email chunxiasu@qq.com; duanxiangguo@nxmu.edu.cnBackground: Colorectal cancer (CRC) is a highly malignant and aggressive gastrointestinal tumor. …”
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21350
Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis
Published 2025-02-01“…Li Huang,1– 3,* Tong Zhang,4,* Yuanyuan Zhu,5 Xueling Lai,6 Hualin Tao,1– 3 Yuhan Xing,5 Zhaoyinqian Li1– 3 1Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, Sichuan, People’s Republic of China; 3Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, Sichuan, People’s Republic of China; 4Department of Laboratory Medicine, Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 5School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, People’s Republic of China; 6Shenzhen Guangming Maternal & Child Healthcare Hospital, Shenzhen, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaoyinqian Li, Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, Sichuan, 646000, People’s Republic of China, Email lizhaoyinqian@swmu.edu.cn Yuhan Xing, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, People’s Republic of China, Email xingyh8@mail.sysu.edu.cnAbstract: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications which exerts detrimental effects on mothers and children. …”
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21351
UPLC-ESI-MS/MS Profile and Antioxidant, Cytotoxic, Antidiabetic, and Antiobesity Activities of the Aqueous Extracts of Three Different Hibiscus Species
Published 2020-01-01“…The aqueous extracts of Hibiscus calyphyllus (HcA), Hibiscus micranthus (HmA), and Hibiscus deflersii (HdA) growing in Saudi Arabia did not receive enough attention in phytochemical and biological studies. This inspired the authors to investigate the phytochemicals of these extracts for the first time using UPLC-ESI-MS/MS in negative and positive ionization modes. …”
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21352
CECT-Based Radiomic Nomogram of Different Machine Learning Models for Differentiating Malignant and Benign Solid-Containing Renal Masses
Published 2025-01-01“…Lu Qian,1,* BinHai Fu,2,* Hong He,2 Shan Liu,1 RenCai Lu2 1Department of Pathology, the First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, 650032, People’s Republic of China; 2Department of Nuclear Medicine, The First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, 650032, People’s Republic of China*These authors contributed equally to this workCorrespondence: RenCai Lu, Department of Nuclear Medicine, The First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Kunming, Yunnan, 650032, People’s Republic of China, Tel +86 087163614503, Email lrc_09@126.comObjective: This study aimed to explore the value of a radiomic nomogram based on contrast-enhanced computed tomography (CECT) for differentiating benign and malignant solid-containing renal masses.Materials and Methods: A total of 122 patients with pathologically confirmed benign (n=47) or malignant (n=75) solid-containing renal masses were enrolled in this study. …”
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21353
Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Chenxin Ke,1,* Yuefeng Yu,1,* Jiang Li,1 Yuetian Yu,1 Ying Sun,1 Yuying Wang,1 Bin Wang,1 Yingli Lu,1 Mengjun Tang,2 Ningjian Wang,1 Yi Chen1 1Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of China; 2Orthopedic Department, Taizhou Hospital of Zhejiang Province, Zhejiang University, Taizhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yi Chen, Email chenyi9h@126.com; Ningjian Wang, Email wnj486@126.comBackground: The blood proteome is a major source of biomarkers and therapeutic targets. …”
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21354
The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma
Published 2025-02-01“…Yintao Wu,* Jianyong Zhu,* Hong Zhang, Nianxin Xia Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nianxin Xia, Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China, Email doctorxnx@163.comPurpose: This study was developed to compare the efficacy of combined D-TACE-HAIC + lenvatinib + PD-1 inhibitor treatment to that of TACE + sorafenib treatment for patients with intermediate and advanced HCC.Patients and Methods: Here, a retrospective analysis of patients with unresectable HCC who underwent transarterial chemoembolization (TACE) from March 2018 to March 2022 at the our hospital was conducted. …”
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21355
Specificity of psychological readiness for changes and personality’s maturity of the employees of the state criminal and executive service
Published 2018-11-01“…The scientific novelty of the research is determined by the fact that the author established, for the first time, the features of psychological readiness for changes of the employees of the Criminal and Executive Service of Ukraine in the context of personal maturity. …”
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21356
Statistical match reports of the 2022 volleyball World Championship in the context of network analysis with Gephi
Published 2023-12-01“…The HITS (Hyperlink-Induced Topic Search) metric assesses the node significance in the graph in terms of hubs and authorities. High HITS values pinpoint pivotal players acting as hubs, signifying their numerous connections with fellow teammates. …”
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21357
Tumor-Stroma Ratio is a Critical Indicator of Peritoneal Metastasis in Gastric Cancer
Published 2025-01-01“…Lin Zhong,1,* Hongyun Huang,2,* Dong Hou,1,* Shihai Zhou,3 Yu Lin,4 Yue Yu,4 Jinhao Yu,1 Fanghai Han,5 Lang Xie6 1Department of Gastrointestinal Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 510120, People’s Republic of China; 2Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100010, People’s Republic of China; 3Department of Tumor Surgery, Zhongshan City People’s Hospital, Zhongshan, Guangdong, 528403, People’s Republic of China; 4Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, People’s Republic of China; 5Department of Gastrointestinal Surgery, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, 5181025, People’s Republic of China; 6Department of General surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lang Xie; Fanghai Han, Email langxiezj@hotmail.com; fh_han@163.comObjective: This study aims to investigate the correlation between the tumor-stroma ratio (TSR) and peritoneal metastasis (PM) in gastric cancer (GC) and constructs a diagnostic model based on preoperative examination data.Methods: To determine the feasibility of obtaining TSR in GC patients through preoperative examinations, the consistency of TSR between endoscopic biopsy tissues and postoperative histopathological tissues was evaluated. …”
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21358
Evaluation of Common and Atypical Clinical Presentations of Tinea Faciei: A Cross-sectional Study from Barabanki, Uttar Pradesh, India
Published 2025-01-01“…Conclusion: The present study offers important insights into various aspects of tinea faciei, including its occurrence, epidemiology, risk factors, and the role of steroid abuse. The authors have described various common and atypical clinical morphologies and distributions of tinea faciei and recognising these atypical signs can help clinicians diagnose the condition early and initiate timely treatment. …”
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21359
Genetic evidence for the causal effects of air pollution on the risk of respiratory diseases
Published 2025-01-01“…Strengthening comprehensive air pollution regulations by relevant authorities could potentially mitigate the risk of these diseases.…”
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21360
Bimodal Patterns of Locomotor Activity and Sleep in Drosophila: A Model for Their Simulation
Published 2025-01-01“…Arcady A Putilov,1,* Evgeniy G Verevkin,1,* Dmitrii V Petrovskii,2,* Lyudmila P Zakharenko2,* 1Independent Research Group “biomedical Systems Math-Modeling”, Berlin, 12489, Germany; 2Department of Insect Genetics, Institute of Cytology and Genetics of the Siberian Branch, the Russian Academy of Sciences, Novosibirsk, 630090, Russia*These authors contributed equally to this workCorrespondence: Arcady A Putilov, Independent Research Group “Biomedical Systems Math-Modeling, 11, Nipkowstr, Berlin, 12489, Germany, Tel/Fax +0049-30-53674643, Email arcady.putilov@gmail.comPurpose: Two previously proposed modelling approaches to explain the bimodal pattern of activity and/or sleep in Drosophila melanogaster are based on 1) the concept of morning and evening oscillators underlying the peaks of activity in the morning and evening, respectively, and 2) the concept of two cycles of buildup and decay of sleep pressure, gated only by the circadian oscillator. …”
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