A Comprehensive Review on the Beneficial Roles of Vitamin D in Skin Health as a Bio-Functional Ingredient in Nutricosmetic, Cosmeceutical, and Cosmetic Applications by Sofia Neonilli A. Papadopoulou, Elena A. Anastasiou, Theodora Adamantidi, Anna Ofrydopoulou, Sophia Letsiou, Alexandros Tsoupras

“…Further research upon vitamin D has exhibited its notable role against skin diseases, such as psoriasis, atopic dermatitis, vitiligo, acne, and rosacea. In this article, a critical review of the most relevant and significant information regarding the relationship between vitamin D and skin health is thoroughly conducted, while emphasis is given to its potential uses and benefits in several cosmetic applications. …”
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Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives by Jia Wu, Yan Wang, Yuqing Wang, Jiawei Ribaudo, Shu Li, Shunyan Hu, Maolin Tang, Yongliang Chen, Yan Long

“…Recently, studies have underscored the pivotal role of EVs in allergic conditions, including asthma, allergic rhinitis, and atopic dermatitis. In this review, we provide a comprehensive overview of recent advances in the separation and characterization of EVs, their roles in allergic diseases, and their diagnostic value as biomarkers. …”
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Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses by Ryutaro Oba, Motomichi Isomura, Akira Igarashi, Kinya Nagata

“…To evaluate the clinical usefulness of these EVs, we measured the serum levels in patients with inflammatory diseases, including Epstein-Barr virus (EBV, n=13) infection, atopic dermatitis (AD, n=10), rheumatoid arthritis (RA, n=20), and osteoarthritis (OA, n=20) and compared the levels with those of healthy adults (n=20). …”
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Global, regional, and national epidemiology of allergic diseases in children from 1990 to 2021: findings from the Global Burden of Disease Study 2021 by Jun Zheng, Yi-jing Jin, Cheng-hai Wang, Chu Feng, Xin-yuan Lai, Shu-qing Hua, Jia-hui Tai

“…Abstract Background Asthma and atopic dermatitis (AD) represent significant global health challenges in children. …”
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Lysosphingolipids in ceramide-deficient skin lipid models by Georgios Paraskevopoulos, Lukáš Opálka, Andrej Kováčik, Anna Paraskevopoulou, Eleni Panoutsopoulou, Irene Sagrafena, Petra Pullmannová, Robert Čáp, Kateřina Vávrová

“…Ceramides are key components of the skin's permeability barrier. In atopic dermatitis, pathological hydrolysis of ceramide precursors - glucosylceramides and sphingomyelin - into lysosphingolipids, specifically glucosylsphingosine (GS) and sphingosine-phosphorylcholine (SPC), and free fatty acids (FFAs) has been proposed to contribute to impaired skin barrier function. …”
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The assessment of the facial skin microbiota in patients with seborrheic dermatitis and metabolic syndrome by Kristina Yu. Molodykh, Elena R. Araviiskaia, Evgeny V. Sokolovskiy, Lyudmila A. Kraeva

“…Currently, the attention of dermatologists is often directed to the study of changes in bacterial colonization of the skin, as one of the important links in the pathogenesis of skin diseases, including psoriasis, atopic dermatitis, acne, and seborrheic dermatitis. In recent years, data have emerged indicating a direct link between changes in the composition of the skin microbiota and obesity, as well as related diseases, primarily type 2 diabetes mellitus. …”
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A Prospective Study Investigating the Health Outcomes of Bitches Neutered Prepubertally or Post-Pubertally by Rachel Moxon, Sarah L. Freeman, Richard M. Payne, Sandra Corr, Gary C. W. England

“…Additionally, PrePN bitches were diagnosed with atopic dermatitis (PrePN: 3.9 ± 0.6 years, PostPN: 1.6 ± 0.3 years; Mann–Whitney U test = 90.5, <i>p</i> = 0.008) and perivulval dermatitis (PrePN: 4.7 ± 0.9 years, PostPN: 0.8 ± 0.1 years; Mann–Whitney U test = 40.0, <i>p</i> = 0.002) at significantly older ages and had lower probabilities of remaining free from otitis externa (χ² = 7.090, D.F. = 1, <i>p</i> = 0.008). …”
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Roads to remission: evolving treatment concepts in type 2 inflammatory diseases by Marek Lommatzsch, Katharina Blumchen, Lisa A. Beck, Jean Bousquet, Guy G. Brusselle, Wytske J. Fokkens, Eckard Hamelmann, Susanne Lau, Hagen Ott, Oliver Pfaar, Hugh A. Sampson, Josef S. Smolen, Christian Taube, Ingo H. Tarner, Martin Wagenmann, Thomas Werfel, Margitta Worm, Harald Renz

“…Summary: Non-communicable diseases (NCDs) characterised by type 2 inflammation, including asthma, allergic rhinitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis, food allergies and eosinophilic esophagitis, are increasing in prevalence worldwide. …”
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مقایسه‌ی اثر درمانی رژیم ترکیبی ملاتونین خوراکی و بتامتازون موضعی با بتامتازون موضعی به تنهایی در درمان آتوپیک درماتیت: کارآزمایی بالینی تصادفی شده... by فریبا ایرجی, امیر حسین سیادت, فاطمه مختاری, سید محسن حسینی, سعید کرمی, سارا سیدیوسفی

“…وضعیت بیماری شرکت‌کنندگان از طریق مقیاس (Scoring Atopic Dermatitis) SCORAD بررسی گردید.یافته‌ها: هر دو گروه درمانی در نمره‌ی SCORAD، وسعت ناحیه‌ی درگیر، شدت بیماری و علائم گزارش شده مانند بی‌خوابی و خارش، تغییرات قابل توجهی را نشان دادند، به طوری که در پایان درمان شاخص SCORAD در گروه مداخله به طور میانگین 14/09 ± 29/44 و در گروه شاهد 16/08 ± 33/56 کاهش یافته بود. …”
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Determinants of prolonged exclusive breastfeeding among children aged 6–23 months in 21 sub-saharan African countries: evidence from nationally representative data by Enyew Getaneh Mekonen

“…Children with prolonged exclusive breastfeeding are more susceptible to anemia, atopic dermatitis, and food allergies. There is no evidence on the pooled prevalence and determinants of prolonged exclusive breastfeeding in sub-Saharan Africa. …”
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Dupilumab in children with eosinophilic esophagitis: a retrospective multicenter study by Mohammed Hasosah, Ghassan Sukkar, Asharf AlSahafi, Ali Zaidan, Nouf Ghous, Abdulmajed Alshahrani, Ziyad Al Zahrani, Naif Hasosah, Mansour Qurashi, Loie Goronfolah, Ali Alsharief, Nagla Kamal

“…It is currently indicated for the treatment of asthma, atopic dermatitis, and EoE. This study aimed to describe children with EoE that is difficult to treat using conventional treatment and to identify symptomatic, histological, and endoscopic improvements after dupilumab treatment. …”
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