Clinical Application of Development of Nonantibiotic Macrolides That Correct Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases by Carmen Rodriguez-Cerdeira, Elena Sanchez-Blanco, Alberto Molares-Vila

“…There are new applications for these macrolides that have been available for several years and have been applied to skin and hair disorders such as atopic dermatitis, oral lichen planus, vitiligo, chronic autoimmune urticaria, rosacea, alopecia areata, pyoderma gangrenosum, Behcet’s disease, neutrophilic dermatosis, and lupus erythematosus. …”
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Very Elevated IgE, Atopy, and Severe Infection: A Genomics-Based Diagnostic Approach to a Spectrum of Diseases by A. Chin, S. Balasubramanyam, C. M. Davis

“…We present a 6-year-old male patient with markedly elevated IgE and severe atopic dermatitis presenting with staphylococcal bacteremia found to have a heterozygous variant in FLG (p.S3247X) and multiple variants of unknown significance in BCL11B, ZAP70, LYST, and PTPRC. …”
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The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier? by Lorena S. Telofski, A. Peter Morello, M. Catherine Mack Correa, Georgios N. Stamatas

“…Additionally, a brief discussion of the properties of the skin barrier in premature neonates and infants with abnormal skin conditions (i.e., atopic dermatitis and eczema) is included. As infant skin continues to mature through the first years of life, it is important that skin care products (e.g., cleansers and emollients) are formulated appropriately. …”
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Skin Biophysical Characteristics in Patients with Keratoconus: A Controlled Study by Reza M. Robati, Bahram Einollahi, Hoda Einollahi, Shima Younespour, Shahed Fadaifard

“…Individuals with connective tissue disorders that affect the skin such as Marfan’s syndrome and Ehlers-Danlos syndrome or patients with atopic dermatitis show an increased prevalence of keratoconus. …”
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Examining allergy related diseases in Africa: A scoping review protocol. by Max Yang Lu, Nadia Shobnam, Alicia A Livinski, Sarini Saksena, Dylan Salters, Michelle Biete, Ian A Myles

“…Worldwide prevalence of allergic diseases has grown to an estimated 262 million for asthma, 400 million for allergic rhinitis (or hay fever), 171 million with atopic dermatitis (or eczema), and over 200 million for food allergy. …”
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Cupping Therapy May be Harmful for Eczema: A PubMed Search by Kam Lun E. Hon, David Chi Kong Luk, Kin Fon Leong, Alexander K. C. Leung

“…Using search words of  “cupping,” “eczema,” and “atopic dermatitis,” only two reports were found on PubMed. …”
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Nasal hyperreactivity and inflammation in allergic rhinitis by I. M. Garrelds, C. de Graaf-in't Veld, R. Gerth van Wijk, F. J. Zijlstra

“…The most important clinical manifestations of IgE-dependent reactions are allergic conjunctivitis, allergic rhinitis, allergic asthma and atopic dermatitis. However, this review will be restricted to allergic rhinitis. …”
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Allergic Contact Dermatitis Reaction to Permanent Tattoo Containing Paraphenylenediamine: A Case Report by Eliot Parascandolo, Samuel Puglisi, Miguel Marenco, Gregory Puglisi

“…A 30-year-old female with a past history of atopic dermatitis and psoriasis presented with a 2-week history of cutaneous reaction to a recent tattoo. …”
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Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin by Michał Biernacki, Elżbieta Skrzydlewska

“…Therefore, it is believed that dysregulation of eicosanoid levels may contribute to the development of skin diseases, such as psoriasis or atopic dermatitis, which in turn suggests that targeted control of the generation of specific eicosanoids may have diagnostic significance and beneficial therapeutic effects. …”
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Development and Validation of a Liquid Chromatography-Mass Spectrometry Assay for Determination of Cromolyn Sodium in Skin Permeation Studies by Miranda Kay Holman, Stacy D Brown, Dorcas Frempong, Ashana Puri, Steven Dinh

“…A topical system would sustain its delivery and may be designed for treatment of atopic dermatitis. Established HPLC protocols for detection of CS are time consuming and intensive, indicating the need for a more streamlined method. …”
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Cellular Anti-Inflammatory and Antioxidant Activities of Bamboo Sasa albomarginata Leaf Extract and Its Constituent Coumaric Acid Methyl Ester by Shiori Kojima, Masatoshi Hakamata, Toshimichi Asanuma, Rie Suzuki, Jun-ichi Tsuruda, Takeshi Nonoyama, Yinzhi Lin, Hitomi Fukatsu, Naoki Koide, Kazuo Umezawa

“…The extract possesses anti-inflammatory activity on the mouse atopic dermatitis model. To elucidate the mechanism of in vivo activity, we have studied the cellular anti-inflammatory and antioxidant activities of the extract and its constituents. …”
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Using fecal microbiota transplantation for animal health (review) by H. Yu. Drobot, S. K. Shebeko, A. M. Ermakov

“…Interestingly, the technique has been successfully used to treat canine atopic dermatitis and monitor age-related changes in fish, thus, confirming the universal nature of this procedure. …”
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Ethanol Extract of Ampelopsis brevipedunculata Rhizomes Suppresses IgE-Mediated Mast Cell Activation and Anaphylaxis by Ji-Yeong Park, Min-Jong Kim, Young-Ae Choi, Seung Woong Lee, Soyoung Lee, Yong Hyun Jang, Sang-Hyun Kim

“…More than 20% of the world’s population suffers from allergic diseases, including allergic asthma, rhinitis, and atopic dermatitis that severely reduce the patient’s quality of life. …”
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Incidence of Keratoconus and Its Association with Systemic Comorbid Conditions: A Nationwide Cohort Study from South Korea by Jong Youn Moon, Jesang Lee, Yoon Hyung Park, Eun-Cheol Park, Si Hyung Lee

“…Adjusted logistic regression analysis after propensity score matching revealed significant associations between keratoconus and allergic rhinitis (odds ratio (OR): 1.86; 95% confidence interval (CI): 1.63–2.13; p<0.001), asthma (OR: 1.20; 95% CI: 1.06–1.36; p<0.001), atopic dermatitis (OR: 1.33; 95% CI: 1.13–1.56; p<0.001), and diabetes mellitus (DM) (OR: 1.35; 95% CI: 1.15–1.58; p<0.001). …”
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A Comprehensive Review on the Beneficial Roles of Vitamin D in Skin Health as a Bio-Functional Ingredient in Nutricosmetic, Cosmeceutical, and Cosmetic Applications by Sofia Neonilli A. Papadopoulou, Elena A. Anastasiou, Theodora Adamantidi, Anna Ofrydopoulou, Sophia Letsiou, Alexandros Tsoupras

“…Further research upon vitamin D has exhibited its notable role against skin diseases, such as psoriasis, atopic dermatitis, vitiligo, acne, and rosacea. In this article, a critical review of the most relevant and significant information regarding the relationship between vitamin D and skin health is thoroughly conducted, while emphasis is given to its potential uses and benefits in several cosmetic applications. …”
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Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives by Jia Wu, Yan Wang, Yuqing Wang, Jiawei Ribaudo, Shu Li, Shunyan Hu, Maolin Tang, Yongliang Chen, Yan Long

“…Recently, studies have underscored the pivotal role of EVs in allergic conditions, including asthma, allergic rhinitis, and atopic dermatitis. In this review, we provide a comprehensive overview of recent advances in the separation and characterization of EVs, their roles in allergic diseases, and their diagnostic value as biomarkers. …”
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Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses by Ryutaro Oba, Motomichi Isomura, Akira Igarashi, Kinya Nagata

“…To evaluate the clinical usefulness of these EVs, we measured the serum levels in patients with inflammatory diseases, including Epstein-Barr virus (EBV, n=13) infection, atopic dermatitis (AD, n=10), rheumatoid arthritis (RA, n=20), and osteoarthritis (OA, n=20) and compared the levels with those of healthy adults (n=20). …”
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Global, regional, and national epidemiology of allergic diseases in children from 1990 to 2021: findings from the Global Burden of Disease Study 2021 by Jun Zheng, Yi-jing Jin, Cheng-hai Wang, Chu Feng, Xin-yuan Lai, Shu-qing Hua, Jia-hui Tai

“…Abstract Background Asthma and atopic dermatitis (AD) represent significant global health challenges in children. …”
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Lysosphingolipids in ceramide-deficient skin lipid models by Georgios Paraskevopoulos, Lukáš Opálka, Andrej Kováčik, Anna Paraskevopoulou, Eleni Panoutsopoulou, Irene Sagrafena, Petra Pullmannová, Robert Čáp, Kateřina Vávrová

“…Ceramides are key components of the skin's permeability barrier. In atopic dermatitis, pathological hydrolysis of ceramide precursors - glucosylceramides and sphingomyelin - into lysosphingolipids, specifically glucosylsphingosine (GS) and sphingosine-phosphorylcholine (SPC), and free fatty acids (FFAs) has been proposed to contribute to impaired skin barrier function. …”
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The assessment of the facial skin microbiota in patients with seborrheic dermatitis and metabolic syndrome by Kristina Yu. Molodykh, Elena R. Araviiskaia, Evgeny V. Sokolovskiy, Lyudmila A. Kraeva

“…Currently, the attention of dermatologists is often directed to the study of changes in bacterial colonization of the skin, as one of the important links in the pathogenesis of skin diseases, including psoriasis, atopic dermatitis, acne, and seborrheic dermatitis. In recent years, data have emerged indicating a direct link between changes in the composition of the skin microbiota and obesity, as well as related diseases, primarily type 2 diabetes mellitus. …”
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