Editorial: Impact of the innate and adaptive immune system in driving type 1 inflammatory skin disease by Mark Mellett, Judit Danis, Barbara Meier-Schiesser

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Methodological Guidelines of the Scientific Community for Human Microbiome Research (CHMR) and the Russian Gastroenterology Association (RGA) on the Use of Probiotics, Prebiotics,... by V. T. Ivashkin, A. V. Gorelov, D. I. Abdulganieva, O. P. Alekseeva, S. A. Alekseenko, A. Yu. Baranovsky, I. N. Zakharova, O. Yu. Zolnikova, K. V. Ivashkin, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammaev, S. V. Nikolaeva, E. A. Poluektova, A. S. Trukhmanov, D. V. Usenko, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, I. V. Berezhnaya, T. L. Lapina, R. V. Maslennikov, N. G. Sugian, A. I. Ulyanin

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Penerapan Euclidean Probability dalam Mendiagnosis Atopik Dermatis by Puji Sari Ramadhan

“…The system that will be formed is by transferring all forms of information and knowledge about Atopic Dermatitis into the diagnosis application using Euclidean Probability analysis. …”
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Biological and psychosocial factors associated with the persistence of pruritus symptoms: protocol for a prospective, exploratory observational study in Germany (individual project... by Sonja Ständer, Stefan W Schneider, Gudrun Schneider, Stefan Kahnert, Manuel Pedro Pereira, Christian Mess, Volker Huck, Konstantin Agelopoulos, Gina Frank

“…Here we aim to identify psychosocial and biological factors and their interactions which might be associated with the persistence of CP with and without immunologic/inflammatory origin, that is, atopic dermatitis and pruritus on non-inflamed skin. We expect that psychosocial factors relevant to the persistence of symptoms such as fatigue and pain may also show associations to CP.Methods and analysis In this prospective, exploratory observational study situated in Germany, three cohorts of 40 patients each with acute exacerbation of atopic dermatitis and chronic atopic dermatitis and 40 CP patients with unaffected skin will be recruited for a comprehensive translational investigation including pruritus-specific and the shared psychosocial assessments of the RU SOMACROSS. …”
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BIOSKIN: A Protocol for the Copenhagen Translational Skin Immunology Biobank and Research Programme by Lone Skov, Jeanne Duus Johansen, Marianne Bengtson Løvendorf

“…Introduction Psoriasis, atopic dermatitis and contact dermatitis are common chronic inflammatory skin diseases that have a significant impact on individuals and society.Methods and analysis The Copenhagen Translational Skin Immunology Biobank and Research Programme (BIOSKIN) is a translational biobank and research study that aims to prospectively collect high-quality biological samples and clinical data from 3000 patients with psoriasis, atopic dermatitis and contact dermatitis over a minimum period of 5 years. …”
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Efficacy and Safety of Immunotherapy with Interferon-Gamma in the Management of Chronic Sulfur Mustard-Induced Cutaneous Complications: Comparison with Topical Betamethasone 1% by Yunes Panahi, Amirhossein Sahebkar, Seyyed Masoud Davoudi, Mojtaba Amiri, Fatemeh Beiraghdar

“…Extent and intensity of cutaneous complications was evaluated using scoring atopic dermatitis (SCORAD) index, and quality of life using dermatology life quality index (DLQI) at baseline and at the end of trial. …”
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Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology by Elena Carmona-Rocha, Lluís Rusiñol, Lluís Puig

“…Phosphodiesterase-4 (PDE4) is involved in the synthesis of inflammatory cytokines that mediate several chronic inflammatory disorders, including psoriasis and atopic dermatitis. In recent years, the therapeutic armamentarium in dermatology has expanded with the introduction of PDE4 inhibitors, both in oral and topical formulations. …”
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Faktor Risiko dan Faktor Pencetus yang Mempengaruhi Kejadian Asma pada Anak di RSUP Dr. M. Djamil Padang by Isnaniyah Usman, Eva Chundrayetti, Oea Khairsyaf

“…The result of the research showed that the risk factors and inducer that affect asthma in children are a weather change (65.91%), dust (63.64%), gender (52.80%), food (43.19%), urticaria in children ( 38.64%), rhinitis in children (34.09%), atopic dermatitis in women (31.82%), atopic dermatitis in children (29.55%), activity (27.27%), rhinitis in the mother ( 22.72%), asthma in women (22.72%), urticaria on the father (20.45%), birth weight <2500 g (15.91%) and nutritional status (obesity) 2.28%. …”
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Allergic conditions and risk of rheumatoid arthritis: a Swedish case–control study by Johan Askling, Lars Klareskog, Lars Alfredsson, Marie Holmqvist, Helga Westerlind, Cynthia S Crowson, Vanessa L Kronzer

“…However, some allergic conditions, notably animal dander allergy, atopic dermatitis and allergic rhinitis, were associated with an increased risk for RA.…”
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Regulation of Dendritic Cell Function in Inflammation by André Said, Günther Weindl

“…We also highlight the functional characteristics of human DC subsets in inflammatory skin environments and skin diseases including psoriasis and atopic dermatitis. Understanding the complex immunoregulatory role of distinct DC subsets in inflamed human skin will be a key element in developing novel strategies in anti-inflammatory therapy.…”
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Post-Genomics and Skin Inflammation by Daniela Braconi, Giulia Bernardini, Annalisa Santucci

“…Atopic dermatitis and psoriasis are two chronic skin inflammatory diseases that have so far received a greater attention within the scientific community through different post-genomic approaches; on the contrary, acne, which is undoubtedly one of the most common skin disorders involving inflammatory processes, seems to be still quite neglected under the post-genomic point of view. …”
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Cutaneous Effects of Notch Inhibitor Therapy: A Report of Two Cases by Claire J. Wiggins, Susan Y. Chon

“…Healthy skin differentiation and homeostasis are reliant on normal Notch expression, and disruption of this signaling has been implicated in dermatological conditions such as hidradenitis suppurativa, psoriasis, atopic dermatitis, and lichen planus. Here, we describe two cases of patients with cutaneous side effects from Notch inhibitor treatment for adenoid cyst carcinoma (ACC) and review the role of Notch signaling in skin disease. …”
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A year in review: new treatments and expanded indications in dermatology in 2024 by Lauren N. McGrath, Lila G. McGrath, John R. Edminister

“…These therapies treat conditions such as atopic dermatitis, hidradenitis suppurativa, prurigo nodularis, molluscum contagiosum, and alopecia areata, among others. …”
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Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus by Nathalie Wurtz, Issam Hasni, Audrey Bancod, Bernard La Scola

“…Ionised active water S-100® has been proposed as an original solution for use in dermocosmetics and for the treatment of wounds such as burns and atopic dermatitis. Among the mechanisms of action that are not completely understood, an antimicrobial activity would appear to be important. …”
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Amarogentin Displays Immunomodulatory Effects in Human Mast Cells and Keratinocytes by Ute Wölfle, Birgit Haarhaus, Christoph M. Schempp

“…The aim of this study was to assess whether bitter compounds display immunomodulatory effects on these immunocompetent cells in the skin, so that they might be a target in chronic inflammatory diseases such as atopic dermatitis and psoriasis. Here, we investigated the impact of amarogentin on substance P-induced release of histamine and TNF-α from the human mast cell line LAD-2. …”
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Analysis of cyt0kine gene expression in stimulated T cells of small children by semi-quantitative PCR by H. Koning, M. R. M. Baert, R. de Groot, H. J. Neijens, H. F. J. Savelkoul

“…This can be performed on T cells purified from blood samples of up to 5 ml in volume from children aged 0–4 years with allergic asthma and atopic dermatitis. This procedure includes multiple sampling of PCR products to determine the linear phase of the PCR; inter-experiment correction using a helper T-cell clone, expressing both IL-4 and IFN-γ; interpatient correction by comparing the expression of a housekeeping gene (HPRT); and finally the development of specific software to analyse densitometric data obtained by scanning photographs of agarose gels, separating PCR products. …”
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Molecular detection of pore-forming leuko toxin in methicillin resistant Staphylococcus aureus isolated from skin infection by Sara A. Al-Ghazal, Huda H. Al-Hassnawi

“…Materials and Methods: All 100 isolates of S. aureus were obtained from clinical samples (burn, wound, impetigo, boil, acne, abuses, folliculated, infected atopic dermatitis, and secondary infection), and 24 of these had been confirmed as MRSA. …”
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Immune Dysfunction in Tourette Syndrome by Ishraga Elamin, Mark J. Edwards, Davide Martino

“…Finally, TS patients could be prone to allergic illnesses (asthma, atopic dermatitis, rhinitis, conjunctivitis), but more work is needed in this area.…”
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Primary Cutaneous CD30+ Anaplastic Large T Cell Lymphoma in a Patient Treated with Cyclosporine for Actinic Reticuloid by T. Gambichler, N. Patsinakidis, L. Susok, M. H. Segert, M. Doerler

“…The association between cyclosporine treatment and development of C-ALCL and other CD30+ lymphoproliferative disorders has previously been reported in patients with atopic dermatitis, psoriasis, and transplant patients. …”
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Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response by Guo Liu, Feng Liu

“…However, excessive Th2 immune response leads to the pathogenesis of Th2 inflammation diseases, including asthma, allergic rhinitis, and atopic dermatitis. Emerging evidence suggest a critical role of the transcription factor Bach2 in regulating Th2 immune responses. …”
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