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581
UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancer
Published 2025-01-01“…The effects of immune cell markers on prognosis were analyzed via univariate Cox regression, least absolute shrinkage and selection operator (LASSO) and gene set variation analysis (GSVA) of bulk sequencing data from The Cancer Genome Atlas (TCGA)-HGSOC cohort. Finally, the effects of key markers on HGSOC cells were evaluated via Cell Counting Kit-8 (CCK-8), Transwell, colony formation, wound healing, immunofluorescence and in vivo tumor growth assays. …”
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582
Screening and validation of tsRNAs associated with lung adenocarcinoma
Published 2025-01-01“…The effects of tsRNAs expression levels on the prognosis of lung adenocarcinoma patients were analyzed based on the Cancer Genome Atlas (TCGA) database (TCGA-LUAD). The target genes were predicted based on TRFtarget2.0 and tRFTar databases. …”
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583
Analysing DNA methylation and transcriptomic signatures to predict prostate cancer recurrence risk
Published 2025-02-01“…This study employs a machine learning approach to identify DNA methylation and RNA expression biomarkers predictive of PCa recurrence using datasets from The Cancer Genome Atlas (TCGA). We analyzed 49,133 genes, identifying 684 differentially methylated genes (DMGs) and 691 differentially expressed genes (DEGs) between recurrence and non-recurrence groups. …”
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584
Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma
Published 2021-01-01“…The transcriptome profiling and clinical data of melanoma were downloaded from The Cancer Genome Atlas database, and their matched normal samples were obtained from the Genotype-Tissue Expression database. …”
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585
Feasibility of implementing family-integrated newborn care for hospitalised preterm and low birthweight infants in newborn care units of Ethiopia: a mixed-methods design
Published 2025-01-01“…Despite the WHO’s call for family engagement in newborn care, evidence of the feasibility of implementation remains scarce.Design An observational feasibility study employing a mixed-methods design comprising a quantitative cross-sectional survey among 157 healthcare providers (HCPs) and a qualitative Participatory Rural Appraisal.Setting The study was conducted in 30 neonatal care units (NCUs) of hospitals in Tigray, Northern Ethiopia.Participants HCPs who were on duty in NCUs during the data collection period were included in the study.Analysis Descriptive statistics were obtained for the quantitative data using STATA V.16, while qualitative data were coded and analysed using a framework analysis approach with qualitative data analysis software (Atlas.ti V.9).Results In total, 157 HCPs were enrolled with a mean (SD) age of 32 (±6.8) years. …”
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586
Mapping Drug-Resistant Tuberculosis Treatment Outcomes in Hunan Province, China
Published 2024-12-01“…Sociodemographic, economic, healthcare, and environmental variables were obtained from various sources, including the WorldClim database, the Malaria Atlas Project, and the Hunan Bureau of Statistics. …”
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587
Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis
Published 2025-01-01“…Using genomic and clinical data from The Cancer Genome Atlas, we identified specific cell components linked to tumor characteristics and genetics. …”
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588
RETRACTED ARTICLE: NR3C2 affects the proliferation and invasiveness of colon cancer cells through the Wnt/β-Catenin signaling pathway
Published 2024-09-01“…Method mRNA (messenger RNA) data and clinical records pertaining to colon cancer were retrieved from The Cancer Genome Atlas (TCGA) database. The analysis of NR3C2 expression discrepancies between normal colon and tumor tissues was conducted using R software. …”
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589
Comprehensive Analysis of Competing Endogenous RNA Network Focusing on Long Noncoding RNA Involved in Cirrhotic Hepatocellular Carcinoma
Published 2021-01-01“…The lncRNA, miRNA, and mRNA expression datasets were obtained from Gene Expression Omnibus and The Cancer Genome Atlas. Based on miRanda and TargetScan, the HCC-specific ceRNA network was constructed to illustrate the coexpression regulatory relationship of lncRNAs, miRNAs, and mRNAs. …”
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590
Seven Immune-Related Genes’ Prognostic Value and Correlation with Treatment Outcome in Head and Neck Squamous Cell Carcinoma
Published 2023-01-01“…Finally, the hub gene’s differential mRNA expression levels were evaluated by means of the Gene Expression Profiling Interactive Analysis (GEPIA), and the Human Protein Atlas (HPA) was utilized for the validation of their translational levels. …”
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591
Identification and Verification of Novel Biomarkers Involving Rheumatoid Arthritis with Multimachine Learning Algorithms: An In Silicon and In Vivo Study
Published 2024-01-01“…We retrieved RA-related and pan-cancer information datasets from the Gene Expression Omnibus and The Cancer Genome Atlas databases, respectively. Six gene expression profiles and corresponding clinical information of GSE12021, GSE29746, GSE55235, GSE55457, GSE77298, and GSE89408 were adopted to perform differential expression gene analysis, enrichment, and immune component difference analyses of RA. …”
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592
Prognostic models of immune-related cell death and stress unveil mechanisms driving macrophage phenotypic evolution in colorectal cancer
Published 2025-01-01“…Furthermore, we performed enrichment analyses and deconvolution algorithms to elucidate the complex interactions between immune cell infiltration and the processes of PCD and stress within a substantial array of transcriptomic data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus data base (GEO) related to CRC. …”
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593
The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution
Published 2024-03-01“…As part of the European Reference Genome Atlas pilot effort to generate reference genomes for European biodiversity, we present the taxonomic description and chromosome-level genome assembly of a newly described species of Nematomorpha (Gordionus montsenyensis Schmidt-Rhaesa & Fernández sp. nov.). …”
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594
Studies on the Removal of Cadmium Toxic Metal Ions by Natural Clays from Aqueous Solution by Adsorption Process
Published 2021-01-01“…The aim of this study is the valorization of the Moroccan clays (QC-MC and QC-MT) from the Middle Atlas region as adsorbents for the treatment of water contaminated by cadmium Cd (II) ions. …”
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595
Identification of Five m6A-Related lncRNA Genes as Prognostic Markers for Endometrial Cancer Based on TCGA Database
Published 2022-01-01“…Gene expression and clinical data were extracted from The Cancer Genome Atlas. Coexpression analysis was performed to identify m6A-related lncRNAs, which were entered into univariate Cox regression models for evaluating the prognosis of UCEC. …”
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596
Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia
Published 2025-02-01“…Methods We systematically first screened the prognostic value of HOXA cluster genes methylation in AML from The Cancer Genome Atlas (TCGA) datasets. Afterwards, the candidate prognosis-related gene HOXA9 were selected for clinical relevance analysis and were further validated in another independent cohort from our research center. …”
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597
Chromosome-level reference genome assembly for the mountain hare (Lepus timidus)
Published 2025-01-01“…Following the previously published brown hare reference genome assembly, the mountain hare is the second Finnish pilot species for the European Reference Genome Atlas (ERGA) initiative, a collaborative effort to generate reference genomes for European biodiversity. …”
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598
Eficacia del sistema de retroalimentación en tiempo real en la práctica profesional de estudiantes de educación física
Published 2025-01-01“…Con el objetivo de conocer la percepción de los estudiantes sobre la eficacia del sistema de retroalimentación se aplicó una entrevista semiestructurada con cuatro preguntas, cuyo análisis se llevó con el software Atlas.ti 24. Resultados: Se generaron cuatro grupos de códigos que muestran: a) el valor de la retroalimentación en tiempo real; b) la importancia de la comunicación para mejorar la praxis pedagógica; c) las tensiones generadas por el Sistema de retroalimentación en la práctica; y d) el reconocimiento de aspectos positivos y áreas de mejora para la implementación del sistema de retroalimentación. …”
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599
Identification and validation of prognostic biomarkers in ccRCC: immune-stromal score and survival prediction
Published 2025-01-01“…Methods Data from the Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) were subjected to analysis to compute immune and stromal scores utilizing the ESTIMATE algorithm. …”
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600
Genetic and neurochemical profiles underlying cortical morphometric vulnerability to Parkinson’s disease
Published 2025-02-01“…Then we performed gene-category enrichment and spatial correlation analyses to evaluate the specific correspondence between cortical alteration in PD and genetic expression from the Allen Human Brain Atlas and normative neurotransmitter atlases from Neuromaps. …”
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